-
2
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr JFR, Wyllie AH, Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26:239-257.
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.R.1
Wyllie, A.H.2
Currie, A.R.3
-
3
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 1995;267:1456-1462.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
4
-
-
0042833078
-
Apoptosis-based drug screening and detection of selective toxicity to cancer cells
-
DOI 10.1097/00001813-200308000-00008
-
Frankfurt OS, Krishan A: Apoptosis-based drug screening and detection of selective toxicity to cancer cells. Anti-cancer Drugs 2003;14:555-561. (Pubitemid 37083161)
-
(2003)
Anti-Cancer Drugs
, vol.14
, Issue.7
, pp. 555-561
-
-
Frankfurt, O.S.1
Krishan, A.2
-
5
-
-
0036962164
-
Resveratrol induces apoptosis in thyroid cancer cell lines via a MAPK- and p53-dependent mechanism
-
DOI 10.1210/jc.87.3.1223
-
Shih A, Davis FB, Lin H-Y, Davis PJ: Resveratrol induces apoptosis in thyroid cancer cell line via a MAPK and p53 dependent mechanism. J Clin Endocrinol Metab 2002;87: 1223-1232. (Pubitemid 36121092)
-
(2002)
Journal of Clinical Endocrinology and Metabolism
, vol.87
, Issue.3
, pp. 1223-1232
-
-
Shih, A.1
Davis, F.B.2
Lin, H.-Y.3
Davis, P.J.4
-
7
-
-
0033602719
-
Differential effects on growth, cell cycle arrest, and induction of apoptosis by resveratrol in human prostate cancer cell lines
-
DOI 10.1006/excr.1999.4471
-
Hsieh TC, Wu JM: Differential effects on growth, cell cycle arrest, and induction of apoptosis by resveratrol in human prostate cancer cell lines. Exp Cell Res 1999;249:109-115. (Pubitemid 29394029)
-
(1999)
Experimental Cell Research
, vol.249
, Issue.1
, pp. 109-115
-
-
Hsieh, T.-C.1
Wu, J.M.2
-
8
-
-
0033152949
-
Resveratrol increases nitric oxide synthase, induces accumulation of p53 and 21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2
-
Hsieh TC, Juan G, Darzynkiewicz Z, Wu ZM: Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p 21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2. Cancer Res 1993;59:2596-2601.
-
(1993)
Cancer Res
, vol.59
, pp. 2596-2601
-
-
Hsieh, T.C.1
Juan, G.2
Darzynkiewicz, Z.3
Wu, Z.M.4
-
9
-
-
34548079498
-
Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein
-
DOI 10.1158/1535-7163.MCT-06-0705
-
Ng AP, Nin DS, Fong JH, Venkataraman D, Chen CS, Khan M: Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein. Mol Cancer Ther 2007;6:2240-2248. (Pubitemid 47294752)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.8
, pp. 2240-2248
-
-
Ng, A.P.P.1
Nin, D.S.2
Fong, J.H.3
Venkataraman, D.4
Chen, C.-S.5
Khan, M.6
-
10
-
-
1542357606
-
Apoptosis pathways in cancer and cancer therapy
-
Debatin KM: Apoptosis pathways in cancer and cancer therapy. Cancer Immunol Immunother 2004;53:153-159.
-
(2004)
Cancer Immunol Immunother
, vol.53
, pp. 153-159
-
-
Debatin, K.M.1
-
11
-
-
0036449793
-
Current status of the molecular mechanisms of anticancer drug-induced apoptosis: The contribution of molecular-level analysis to cancer chemotherapy
-
DOI 10.1007/s00280-002-0522-7
-
Kim R, Tanabe K, Uchida Y, Emi M, Inoue H, Toge T: Current status of the molecular mechanisms of anticancer drug induced apoptosis. The contribution of molecular-level analysis to cancer chemotherapy. Cancer Chemother Pharmacol 2002;50:343-352. (Pubitemid 35440522)
-
(2002)
Cancer Chemotherapy and Pharmacology
, vol.50
, Issue.5
, pp. 343-352
-
-
Kim, R.1
Tanabe, K.2
Uchida, Y.3
Emi, M.4
Inoue, H.5
Toge, T.6
-
14
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of mdM2
-
DOI 10.1126/science.1092472
-
Vassilev LT, Vu BT, Graves B, et al.: In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 2004;303:844-848. (Pubitemid 38174664)
-
(2004)
Science
, vol.303
, Issue.5659
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
Fotouhi, N.11
Liu, E.A.12
-
16
-
-
0032585793
-
Expression of mdm-20 oncoprotein in the primary and metastatic sites of mammary tumor (GI-101) implanted athymic nude mice
-
Rathinavelu P, Malave A, Raney SR, Hurst J, Roberson CT, Rathinavelu A: Expression of mdm-2 oncoprotein in the primary and metastatic sites of mammary tumor (GI-101) implanted athymic nude mice. Cancer Biochem Biophys 1999;17:133-146. (Pubitemid 29475253)
-
(1999)
Cancer Biochemistry Biophysics
, vol.17
, Issue.1-2
, pp. 133-146
-
-
Rathinavelu, P.1
Malave, A.2
Raney, S.R.3
Hurst, J.4
Roberson, C.T.5
Rathinavelu, A.6
-
18
-
-
0032520061
-
Short alternative splice transcripts of the mdm2 oncogene correlate to malignancy in human astrocytic neoplasms
-
Matsumoto R, Tada M, Nozaki M, Zhang CL, Sawamura Y, Abe H: Short alternative splice transcripts of the mdm2 oncogene correlate to malignancy in human astrocytic neoplasms. Cancer Res 1998;58:609-613. (Pubitemid 28099465)
-
(1998)
Cancer Research
, vol.58
, Issue.4
, pp. 609-613
-
-
Matsumoto, R.1
Tada, M.2
Nozaki, M.3
Zhang, C.-L.4
Sawamura, Y.5
Abe, H.6
-
19
-
-
0026095666
-
Defining protective responses to pathogens: Cytokine profiles in leprosy lesions
-
Yamamura M, Uyemura K, Deans RJ, Weinberg K, Rea TH: Defining protective responses to pathogens: cytokine profiles in leprosy lesions. Science 1991;254:277-279. (Pubitemid 21917340)
-
(1991)
Science
, vol.254
, Issue.5029
, pp. 277-279
-
-
Yamamura, M.1
Uyemura, K.2
Deans, R.J.3
Weinberg, K.4
Rea, T.H.5
Bloom, B.R.6
Modlin, R.L.7
-
20
-
-
84873626265
-
Induction of apoptosis by resveratrol in cancer cells during combination treatment with nutlin-3 and TGF-b
-
University of Miami Leonard M. Miller School of Medicine, Miami
-
Kaur K, Pervez FF, Jasani V, Bukhari N, Narasimhan M, Rathinavelu A: Induction of apoptosis by resveratrol in cancer cells during combination treatment with nutlin-3 and TGF-b. In: Miami Winter Symposium, 2006 Proceedings, University of Miami Leonard M. Miller School of Medicine, Miami, 2006.
-
(2006)
Miami Winter Symposium, 2006 Proceedings
-
-
Kaur, K.1
Pervez, F.F.2
Jasani, V.3
Bukhari, N.4
Narasimhan, M.5
Rathinavelu, A.6
-
21
-
-
4143140856
-
Trans-3,4,5-Trihydroxystibene inhibits hypoxia-inducible factor 1α and vascular endothelial growth factor expression in human ovarian cancer cells
-
DOI 10.1158/1078-0432.CCR-03-0588
-
Cao ZJ, Xia C, Shi X, Jiang B-H: Trans-3,4,5-trihydroxystibene inhibits hypoxia-inducible factor-1 and vascular endothelial growth factor expression in human ovarian cancer cells. Clin Cancer Res 2004;10:5253-5263. (Pubitemid 39099800)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.15
, pp. 5253-5263
-
-
Cao, Z.1
Fang, J.2
Xia, C.3
Shi, X.4
Jiang, B.-H.5
-
22
-
-
0033168928
-
Cisplatin-induced apoptosis proceeds by caspase-3-dependent and - independent pathways in cisplatin-resistant and -sensitive human ovarian cancer cell lines
-
Henkels MH, Turchi JJ: Cisplatin induced apoptosis proceeds by caspase-3 dependent and independent pathways in cisplatin resistant and sensitive human ovarian cancer cell line. Cancer Res 1999;59:3077-3083. (Pubitemid 29316005)
-
(1999)
Cancer Research
, vol.59
, Issue.13
, pp. 3077-3083
-
-
Henkels, K.M.1
Turchi, J.J.2
-
23
-
-
0035874886
-
Resveratrol induces extensive apoptosis by depolarizing mitochondrial membranes and activating caspase-9 in acute lymphoblastic leukemia cells
-
Dörrie J, Gerauer H, Wachter Y, Zunino SJ: Resveratrol induces extensive apoptosis by depolarizing mitochondrial membranes and activating caspase-9 in acute lymphoblastic leukemia cells. Cancer Res 2001;61:4731-4739. (Pubitemid 32691883)
-
(2001)
Cancer Research
, vol.61
, Issue.12
, pp. 4731-4739
-
-
Dorrie, J.1
Gerauer, H.2
Wachter, Y.3
Zunino, S.J.4
-
24
-
-
34447625529
-
Effects of genistein on cell cycle and apoptosis of two murine melanoma cell lines
-
Hongzhong W, Yu Z, Chonghua L, Liping X, Guang C, Yan-cheng N, Rongqing Z: Effects of genistein on cell cycle and apoptosis of two murine melanoma cell lines. Tsinghua Sci Technol 2007;12:372-380.
-
(2007)
Tsinghua Sci Technol
, vol.12
, pp. 372-380
-
-
Hongzhong, W.1
Yu, Z.2
Chonghua, L.3
Liping, X.4
Guang, C.5
Yan-Cheng, N.6
Rongqing, Z.7
-
25
-
-
0028903933
-
Reduction in mito-chondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
-
Zamzami N, Marchetti P, Castedo M, et al.: Reduction in mito-chondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J Exp Med 1995;181:1661-1672.
-
(1995)
J Exp Med
, vol.181
, pp. 1661-1672
-
-
Zamzami, N.1
Marchetti, P.2
Castedo, M.3
-
26
-
-
0037879052
-
The mitochondrial membrane potential (dwm) in apoptosis; an update
-
DOI 10.1023/A:1022945107762
-
Ly JD, Grubb DR, Lawen A: The mitochondrial membrane potential (dwm) in apoptosis; an update. Apoptosis 2003;8:115-128. (Pubitemid 36553052)
-
(2003)
Apoptosis
, vol.8
, Issue.2
, pp. 115-128
-
-
Ly, J.D.1
Grubb, D.R.2
Lawen, A.3
-
27
-
-
9544246860
-
Mitochondrial permeability transition is a central coordinating event of apoptosis
-
Marchetti P, Castedo M, Susin SA, et al.: Mitochondrial permeability transition is a central coordinating event of apoptosis. J Exp Med 1996;184:1155-1160. (Pubitemid 26313572)
-
(1996)
Journal of Experimental Medicine
, vol.184
, Issue.3
, pp. 1155-1160
-
-
Marchetti, P.1
Castedo, M.2
Susin, S.A.3
Zamzami, N.4
Hirsch, T.5
Macho, A.6
Haeffner, A.7
Hirsch, F.8
Geuskens, M.9
Kroemer, G.10
-
28
-
-
0027374638
-
A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro- 1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1)
-
DOI 10.1006/bbrc.1993.2438
-
0- tetraethylbenzimidazolcarbocyanine iodide (JC-1). Biochem Biophys Res Commun 1993;197:40-45. (Pubitemid 23358874)
-
(1993)
Biochemical and Biophysical Research Communications
, vol.197
, Issue.1
, pp. 40-45
-
-
Cossarizza, A.1
Baccarani-Contri, M.2
Kalashnikova, G.3
Franceschi, C.4
-
29
-
-
27644505459
-
Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1
-
DOI 10.1073/pnas.0507900102
-
Hyun-Eui Kim, Fenghe Du, Min Fang, and Xiaodong Wang: Formation of apoptosome is initiated by cytochrome C-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1. Proc Natl Acad Sci 2005;102:17545-17550. (Pubitemid 41803534)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.49
, pp. 17545-17550
-
-
Kim, H.-E.1
Du, F.2
Fang, M.3
Wang, X.4
-
30
-
-
0030785790
-
The central executioner of apoptosis: Multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis
-
DOI 10.1084/jem.186.1.25
-
Susin S, Zamzami N, Castedo M, et al.: The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95-and ceramide-induced apoptosis. J Expt Med 1997;186:25-37. (Pubitemid 27304844)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.1
, pp. 25-37
-
-
Susin, S.A.1
Zamzami, N.2
Castedo, M.3
Daugas, E.4
Wang, H.-G.5
Geley, S.6
Fassy, F.7
Reed, J.C.8
Kroemer, G.9
-
31
-
-
0345862319
-
Nutraceuticals, apoptosis, and disease prevention
-
DOI 10.1016/j.nut.2003.09.017
-
Gosslau A, Chen KY: Nutraceuticals, apoptosis, and disease prevention. Nutrition 2004;20:95-102. (Pubitemid 38091587)
-
(2004)
Nutrition
, vol.20
, Issue.1
, pp. 95-102
-
-
Gosslau, A.1
Chen, K.Y.2
-
32
-
-
84864185309
-
Cy-totoxic effect of carvacrol on human cervical cancer cells
-
Mehdi SJ, Ahmad A, Irshad M, Manzoor N, Rizvi MMA: Cy-totoxic effect of carvacrol on human cervical cancer cells. Biol Med 2011;3:307-312.
-
(2011)
Biol Med
, vol.3
, pp. 307-312
-
-
Mehdi, S.J.1
Ahmad, A.2
Irshad, M.3
Manzoor, N.4
Rizvi, M.M.A.5
-
33
-
-
0029590161
-
MDM2 transformation in the absence of p53 and abrogation of the p107 G1 cell-cycle arrest
-
Dubs-Poterszman M.C, Tocque B, Wasylyk B: MDM2 transformation in the absence of p53 and abrogation of the p107 G1 cell-cycle arrest. Oncogene 1995;11:2445-2449. (Pubitemid 26008423)
-
(1995)
Oncogene
, vol.11
, Issue.11
, pp. 2445-2449
-
-
Dubs-Poterszman, M.-C.1
Tocque, B.2
Wasylyk, B.3
-
34
-
-
33751415080
-
P53-independent induction of rat hepatic Mdm2 following administration of phenobarbital and pregnenolone 16α-carbonitrile
-
DOI 10.1093/toxsci/kfl115
-
Nelson DM, Bhaskaran V, Foster WR, Lehman-Mc Keeman LD: p53 Independent induction of rat hepatic Mdm2 following administration of phenobarbital and pregnenolone 16 alpha-carbonitrile. Toxicol Sci 2006;94:272-280. (Pubitemid 44817143)
-
(2006)
Toxicological Sciences
, vol.94
, Issue.2
, pp. 272-280
-
-
Nelson, D.M.1
Bhaskaran, V.2
Foster, W.R.3
Lehman-McKeeman, L.D.4
-
35
-
-
0032417695
-
Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis
-
DOI 10.1073/pnas.95.26.15608
-
Jones, SN, Hancock AR, Vogel H, Donehower LA, Bradley A: Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis. Proc Natl Acad Sci USA 1998; 95:15608-15612. (Pubitemid 29018747)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.26
, pp. 15608-15612
-
-
Jones, S.N.1
Hancock, A.R.2
Vogel, H.3
Donehower, L.A.4
Bradley, A.5
|