메뉴 건너뛰기




Volumn 91, Issue 1, 2013, Pages 31-37

Oxidative stress and cancer pain

Author keywords

Bone; Cancer; Glutamate; Oxidative stress; Pain; Sulfasalazine; System x C

Indexed keywords

CYSTINE; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 5; GLUTAMIC ACID; IONOTROPIC RECEPTOR; MELOXICAM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; REACTIVE OXYGEN METABOLITE; SALAZOSULFAPYRIDINE;

EID: 84873589271     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2012-0298     Document Type: Review
Times cited : (9)

References (95)
  • 1
    • 23144433297 scopus 로고    scopus 로고
    • Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo
    • doi:10.1215/S1152851704000961. PMID:16053698
    • Arcella, A., Carpinelli, G., Battaglia, G., D'Onofrio, M., Santoro, F., Ngomba, R.T., et al. 2005. Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo. Neuro. Oncol. 7(3): 236-245. doi:10.1215/S1152851704000961. PMID:16053698.
    • (2005) Neuro. Oncol , vol.7 , Issue.3 , pp. 236-245
    • Arcella, A.1    Carpinelli, G.2    Battaglia, G.3    D'Onofrio, M.4    Santoro, F.5    Ngomba, R.T.6
  • 2
    • 8744226622 scopus 로고    scopus 로고
    • The role of glutathione in cancer
    • doi:10.1002/cbf.1149. PMID: 15386533
    • Balendiran, G.K., Dabur, R., and Fraser, D. 2004. The role of glutathione in cancer. Cell Biochem. Funct. 22(6): 343-352. doi:10.1002/cbf.1149. PMID: 15386533.
    • (2004) Cell Biochem. Funct , vol.22 , Issue.6 , pp. 343-352
    • Balendiran, G.K.1    Dabur, R.2    Fraser, D.3
  • 3
    • 40449094829 scopus 로고    scopus 로고
    • The cystine/cysteine cycle: A redox cycle regulating susceptibility versus resistance to cell death
    • doi:10.1038/sj.onc.1210796. PMID:17828297
    • Banjac, A., Perisic, T., Sato, H., Seiler, A., Bannai, S., Weiss, N., et al. 2008. The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death. Oncogene, 27(11): 1618-1628. doi:10.1038/sj.onc.1210796. PMID:17828297.
    • (2008) Oncogene , vol.27 , Issue.11 , pp. 1618-1628
    • Banjac, A.1    Perisic, T.2    Sato, H.3    Seiler, A.4    Bannai, S.5    Weiss, N.6
  • 4
    • 0024210681 scopus 로고
    • A novel function of glutamine in cell culture: Utilization of glutamine for the uptake of cystine in human fibroblasts
    • doi:10.1002/jcp.1041370221. PMID:2903864
    • Bannai, S., and Ishii, T. 1988. A novel function of glutamine in cell culture: utilization of glutamine for the uptake of cystine in human fibroblasts. J. Cell. Physiol. 137(2): 360-366. doi:10.1002/jcp.1041370221. PMID:2903864.
    • (1988) J. Cell. Physiol , vol.137 , Issue.2 , pp. 360-366
    • Bannai, S.1    Ishii, T.2
  • 5
    • 0018963749 scopus 로고
    • Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture
    • PMID:, 7358676
    • Bannai, S., and Kitamura, E. 1980. Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture. J. Biol. Chem. 255(6): 2372-2376. PMID:7358676.
    • (1980) J. Biol. Chem , vol.255 , Issue.6 , pp. 2372-2376
    • Bannai, S.1    Kitamura, E.2
  • 7
    • 33847793783 scopus 로고    scopus 로고
    • Glutamate receptors and pain
    • doi:10.1016/j.semcdb.2006.10.008. PMID: 17110139
    • Bleakman, D., Alt, A., and Nisenbaum, E.S. 2006. Glutamate receptors and pain. Semin. Cell Dev. Biol. 17(5): 592-604. doi:10.1016/j.semcdb.2006.10.008. PMID: 17110139.
    • (2006) Semin. Cell Dev. Biol , vol.17 , Issue.5 , pp. 592-604
    • Bleakman, D.1    Alt, A.2    Nisenbaum, E.S.3
  • 8
    • 79958097544 scopus 로고    scopus 로고
    • Breast cancer-induced bone remodeling, skeletal pain, and sprouting of sensory nerve fibers
    • doi:10.1016/j.jpain.2010.12.016. PMID:21497141
    • Bloom, A.P., Jimenez-Andrade, J.M., Taylor, R.N., Castaneda-Corral, G., Kaczmarska, M.J., Freeman, K.T., et al. 2011. Breast cancer-induced bone remodeling, skeletal pain, and sprouting of sensory nerve fibers. J. Pain, 12(6): 698-711. doi:10.1016/j.jpain.2010.12.016. PMID:21497141.
    • (2011) J. Pain , vol.12 , Issue.6 , pp. 698-711
    • Bloom, A.P.1    Jimenez-Andrade, J.M.2    Taylor, R.N.3    Castaneda-Corral, G.4    Kaczmarska, M.J.5    Freeman, K.T.6
  • 9
    • 0033428385 scopus 로고    scopus 로고
    • Effects of nonsteroidal anti-inflammatory drugs on renal function: Focus on cyclooxygenase-2-selective inhibition
    • ; discussion 70S-71S, doi:10.1016/S0002-9343(99)00369-1. PMID: 10628595
    • Brater, D.C. 1999. Effects of nonsteroidal anti-inflammatory drugs on renal function: focus on cyclooxygenase-2-selective inhibition. Am. J. Med. 107(6A): 65S-70S; discussion 70S-71S. doi:10.1016/S0002-9343(99)00369-1. PMID: 10628595.
    • (1999) Am. J. Med , vol.107 , Issue.6 A
    • Brater, D.C.1
  • 10
    • 80054006943 scopus 로고    scopus 로고
    • Glutamate release by primary brain tumors induces epileptic activity
    • doi:doi:10.1038/nm.2453. PMID: PMID:21909104
    • Buckingham, S.C., Campbell, S.L., Haas, B.R., Montana, V., Robel, S., Ogunrinu, T., et al. 2011. Glutamate release by primary brain tumors induces epileptic activity. Nat. Med. 17(10): 1269-1274. doi:doi:10.1038/nm.2453. PMID: PMID:21909104.
    • (2011) Nat. Med , vol.17 , Issue.10 , pp. 1269-1274
    • Buckingham, S.C.1    Campbell, S.L.2    Haas, B.R.3    Montana, V.4    Robel, S.5    Ogunrinu, T.6
  • 11
    • 33644625829 scopus 로고    scopus 로고
    • Ketamine attenuates glutamate-induced mechanical sensitization of the masseter muscle in human males
    • doi: 10.1007/s00221-005-0158-z. PMID:16292641
    • Cairns, B.E., Svensson, P., Wang, K., Castrillon, E., Hupfeld, S., Sessle, B. J.et al. 2006. Ketamine attenuates glutamate-induced mechanical sensitization of the masseter muscle in human males. Exp. Brain Res. 169(4): 467-472. doi: 10.1007/s00221-005-0158-z. PMID:16292641.
    • (2006) Exp. Brain Res , vol.169 , Issue.4 , pp. 467-472
    • Cairns, B.E.1    Svensson, P.2    Wang, K.3    Castrillon, E.4    Hupfeld, S.5    Sessle, B.J.6
  • 12
    • 0032813617 scopus 로고    scopus 로고
    • An international survey of cancer pain characteristics and syndromes. IASP Task Force on Cancer Pain. International Association for the Study of Pain
    • doi:10.1016/S0304, 3959(99)00073-1. PMID:10488677
    • Caraceni, A., and Portenoy, R.K. 1999. An international survey of cancer pain characteristics and syndromes. IASP Task Force on Cancer Pain. International Association for the Study of Pain. Pain, 82: 263-274. doi:10.1016/S03043959(99)00073-1. PMID:10488677.
    • (1999) Pain , vol.82 , pp. 263-274
    • Caraceni, A.1    Portenoy, R.K.2
  • 13
    • 2942637938 scopus 로고    scopus 로고
    • Breakthrough pain characteristics and syndromes in patients with cancer pain. An international survey
    • doi:10.1191/ 0269216304pm890oa. PMID:15198130
    • Caraceni, A., Martini, C., Zecca, E., Portenoy, R.K., Ashby, M.A., Hawson, G., et al. 2004. Breakthrough pain characteristics and syndromes in patients with cancer pain. An international survey. Palliat. Med. 18(3): 177-183. doi:10.1191/ 0269216304pm890oa. PMID:15198130.
    • (2004) Palliat. Med , vol.18 , Issue.3 , pp. 177-183
    • Caraceni, A.1    Martini, C.2    Zecca, E.3    Portenoy, R.K.4    Ashby, M.A.5    Hawson, G.6
  • 14
    • 0033608399 scopus 로고    scopus 로고
    • Inflammation-induced changes in peripheral glutamate receptor populations
    • doi:10. 1016/S0006-8993(98)01328-6. PMID:10023031
    • Carlton, S.M., and Coggeshall, R.E. 1999. Inflammation-induced changes in peripheral glutamate receptor populations. Brain Res. 820(1-2): 63-70. doi:10. 1016/S0006-8993(98)01328-6. PMID:10023031.
    • (1999) Brain Res , vol.820 , Issue.1-2 , pp. 63-70
    • Carlton, S.M.1    Coggeshall, R.E.2
  • 15
    • 0029052635 scopus 로고
    • Localization and activation of glutamate receptors in unmyelinated axons of rat glabrous skin
    • doi:10.1016/0304-3940(95)11889-5. PMID: 8545047
    • Carlton, S.M., Hargett, G.L., and Coggeshall, R.E. 1995. Localization and activation of glutamate receptors in unmyelinated axons of rat glabrous skin. Neurosci. Lett. 197(1): 25-28. doi:10.1016/0304-3940(95)11889-5. PMID: 8545047.
    • (1995) Neurosci. Lett , vol.197 , Issue.1 , pp. 25-28
    • Carlton, S.M.1    Hargett, G.L.2    Coggeshall, R.E.3
  • 16
    • 0035665602 scopus 로고    scopus 로고
    • Heteromeric amino acid transporters: Biochemistry, genetics, and physiology
    • PMID:, 11704550
    • Chillarón, J., Roca, R., Valencia, A., Zorzano, A., and Palacin, M. 2001. Heteromeric amino acid transporters: biochemistry, genetics, and physiology. Am. J. Physiol. Renal Physiol. 281(6): F995-F1018. PMID:11704550.
    • (2001) Am. J. Physiol. Renal Physiol , vol.281 , Issue.6
    • Chillarón, J.1    Roca, R.2    Valencia, A.3    Zorzano, A.4    Palacin, M.5
  • 17
    • 0025570260 scopus 로고
    • Uptake of glutamate and cysteine in C-6 glioma cells and in cultured astrocytes
    • doi:10.1111/j.14714159.1990.tb05800.x. PMID:1977889
    • Cho, Y., and Bannai, S. 1990. Uptake of glutamate and cysteine in C-6 glioma cells and in cultured astrocytes. J. Neurochem. 55(6): 2091-2097. doi:10.1111/j.14714159.1990.tb05800.x. PMID:1977889.
    • (1990) J. Neurochem , vol.55 , Issue.6 , pp. 2091-2097
    • Cho, Y.1    Bannai, S.2
  • 18
    • 23444449591 scopus 로고    scopus 로고
    • Inhibition of cystine uptake disrupts the growth of primary brain tumors
    • doi:10.1523/JNEUROSCI.5258-04.2005. PMID:16079392
    • Chung, W.J., Lyons, S.A., Nelson, G.M., Hamza, H., Gladson, C.L., Gillespie, G.Y., et al. 2005. Inhibition of cystine uptake disrupts the growth of primary brain tumors. J. Neurosci. 25(31): 7101-7110. doi:10.1523/JNEUROSCI.5258-04.2005. PMID:16079392.
    • (2005) J. Neurosci , vol.25 , Issue.31 , pp. 7101-7110
    • Chung, W.J.1    Lyons, S.A.2    Nelson, G.M.3    Hamza, H.4    Gladson, C.L.5    Gillespie, G.Y.6
  • 19
    • 33750726077 scopus 로고    scopus 로고
    • Clinical features of metastatic bone disease and risk of skeletal morbidity
    • 10.1158/1078-0432.CCR-06-0931
    • Coleman, R.E. 2006. Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin. Cancer Res. 12(20): 6243s-6249s. 10.1158/1078-0432.CCR-06-0931.
    • (2006) Clin. Cancer Res , vol.12 , Issue.20
    • Coleman, R.E.1
  • 20
    • 0023137823 scopus 로고
    • The clinical course of bone metastases from breast cancer
    • doi:10.1038/bjc.1987.13. PMID: 3814476
    • Coleman, R.E., and Rubens, R.D. 1987. The clinical course of bone metastases from breast cancer. Br. J. Cancer, 55(1): 61-66. doi:10.1038/bjc.1987.13. PMID: 3814476.
    • (1987) Br. J. Cancer , vol.55 , Issue.1 , pp. 61-66
    • Coleman, R.E.1    Rubens, R.D.2
  • 21
    • 84873607054 scopus 로고    scopus 로고
    • Glutamate signaling in healthy and diseased bone
    • doi:10.3389/fendo.2012.00089. PMID:22833735
    • Cowan, R.W., Seidlitz, E.P., and Singh, G. 2012. Glutamate signaling in healthy and diseased bone. Front. Endocrinol. (Lausanne), 3: 89. doi:10.3389/fendo.2012.00089. PMID:22833735.
    • (2012) Front. Endocrinol. (Lausanne) , vol.3 , pp. 89
    • Cowan, R.W.1    Seidlitz, E.P.2    Singh, G.3
  • 22
    • 84861014659 scopus 로고    scopus 로고
    • Characterization of a rat model of metastatic prostate cancer bone pain
    • PMID:21197325
    • De Ciantis, P., Yashpal, K., Henry, J.L., and Singh, G. 2010. Characterization of a rat model of metastatic prostate cancer bone pain. J. Pain Res. 3: 213-221. PMID:21197325.
    • (2010) J. Pain Res , vol.3 , pp. 213-221
    • de Ciantis, P.1    Yashpal, K.2    Henry, J.L.3    Singh, G.4
  • 23
  • 24
    • 33846628923 scopus 로고    scopus 로고
    • Sulfasalazine-induced cystine starvation: Potential use for prostate cancer therapy
    • doi:10.1002/pros.20508. PMID:17075799
    • Doxsee, D.W., Gout, P.W., Kurita, T., Lo, M., Buckley, A.R., Wang, Y., et al. 2007. Sulfasalazine-induced cystine starvation: potential use for prostate cancer therapy. Prostate, 67(2): 162-171. doi:10.1002/pros.20508. PMID:17075799.
    • (2007) Prostate , vol.67 , Issue.2 , pp. 162-171
    • Doxsee, D.W.1    Gout, P.W.2    Kurita, T.3    Lo, M.4    Buckley, A.R.5    Wang, Y.6
  • 25
    • 0035152963 scopus 로고    scopus 로고
    • Glutamate receptors and nociception: Implications for the drug treatment of pain
    • doi:10.2165/00023210200115010-00004. PMID:11465012
    • Fundytus, M.E. 2001. Glutamate receptors and nociception: implications for the drug treatment of pain. CNS Drugs, 15(1): 29-58. doi:10.2165/00023210200115010-00004. PMID:11465012.
    • (2001) CNS Drugs , vol.15 , Issue.1 , pp. 29-58
    • Fundytus, M.E.1
  • 26
    • 33744942376 scopus 로고    scopus 로고
    • Acid-mediated tumor invasion: A multidisciplinary study
    • doi:10.1158/0008-5472.CAN-05-4193. PMID:16707446
    • Gatenby, R.A., Gawlinski, E.T., Gmitro, A.F., Kaylor, B., and Gillies, R.J. 2006. Acid-mediated tumor invasion: a multidisciplinary study. Cancer Res. 66(10): 5216-5223. doi:10.1158/0008-5472.CAN-05-4193. PMID:16707446.
    • (2006) Cancer Res , vol.66 , Issue.10 , pp. 5216-5223
    • Gatenby, R.A.1    Gawlinski, E.T.2    Gmitro, A.F.3    Kaylor, B.4    Gillies, R.J.5
  • 27
    • 0012084452 scopus 로고
    • Free and bound glutamate in natural products
    • Edited by L. Filer, S. Garattini, M. Kare, W. Reynolds, and R. Wurtman New York: Raven Press
    • Giacometti, T. 1979. Free and bound glutamate in natural products. In Glutamic acid: advances in biochemistry and physiology. Edited by L. Filer, S. Garattini, M. Kare, W. Reynolds, and R. Wurtman New York: Raven Press. pp. 25-34.
    • (1979) Glutamic Acid: Advances In Biochemistry and Physiology , pp. 25-34
    • Giacometti, T.1
  • 28
    • 0034772516 scopus 로고    scopus 로고
    • Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c) cystine transporter: A new action for an old drug
    • doi: 10.1038/sj.leu.2402238. PMID:11587223
    • Gout, P.W., Buckley, A.R., Simms, C.R., and Bruchovsky, N. 2001. Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c) cystine transporter: a new action for an old drug. Leukemia, 15(10): 1633-1640. doi: 10.1038/sj.leu.2402238. PMID:11587223.
    • (2001) Leukemia , vol.15 , Issue.10 , pp. 1633-1640
    • Gout, P.W.1    Buckley, A.R.2    Simms, C.R.3    Bruchovsky, N.4
  • 29
    • 67349136816 scopus 로고    scopus 로고
    • The xccystine/glutamate antiporter as a potential therapeutic target for small-cell lung cancer: Use of sulfasalazine
    • doi:10.1007/s00280-008-0894-4. PMID:19104813
    • Guan, J., Lo, M., Dockery, P., Mahon, S., Karp, C.M., Buckley, A.R., et al. 2009. The xccystine/glutamate antiporter as a potential therapeutic target for small-cell lung cancer: use of sulfasalazine. Cancer Chemother. Pharmacol. 64(3): 463-472. doi:10.1007/s00280-008-0894-4. PMID:19104813.
    • (2009) Cancer Chemother. Pharmacol , vol.64 , Issue.3 , pp. 463-472
    • Guan, J.1    Lo, M.2    Dockery, P.3    Mahon, S.4    Karp, C.M.5    Buckley, A.R.6
  • 30
    • 33748165207 scopus 로고    scopus 로고
    • Similarities and differences in tumor growth, skeletal remodeling and pain in an osteolytic and osteoblastic model of bone cancer
    • doi:10.1097/01.ajp.0000210902.67849.e6. PMID:16926574
    • Halvorson, K.G., Sevcik, M.A., Ghilardi, J.R., Rosol, T.J., and Mantyh, P.W. 2006. Similarities and differences in tumor growth, skeletal remodeling and pain in an osteolytic and osteoblastic model of bone cancer. Clin. J. Pain, 22(7): 587-600. doi:10.1097/01.ajp.0000210902.67849.e6. PMID:16926574.
    • (2006) Clin. J. Pain , vol.22 , Issue.7 , pp. 587-600
    • Halvorson, K.G.1    Sevcik, M.A.2    Ghilardi, J.R.3    Rosol, T.J.4    Mantyh, P.W.5
  • 31
    • 0034655822 scopus 로고    scopus 로고
    • Herniated lumbar disc material as a source of free glutamate available to affect pain signals through the dorsal root ganglion
    • doi: 10.1097/00007632-200004150-00006. PMID:10767804
    • Harrington, J.F., Messier, A.A., Bereiter, D., Barnes, B., and Epstein, M.H. 2000. Herniated lumbar disc material as a source of free glutamate available to affect pain signals through the dorsal root ganglion. Spine, 25: 929-936. doi:10.1097/00007632-200004150-00006. PMID:10767804.
    • (2000) Spine , vol.25 , pp. 929-936
    • Harrington, J.F.1    Messier, A.A.2    Bereiter, D.3    Barnes, B.4    Epstein, M.H.5
  • 32
    • 0034130227 scopus 로고    scopus 로고
    • Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons
    • doi:10.1016/ S0306-4522(00)00110-X. PMID:10869852
    • Honore, P., Rogers, S.D., Schwei, M.J., Salak-Johnson, J.L., Luger, N.M., Sabino, M.C., et al. 2000. Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons. Neuroscience, 98(3): 585-598. doi:10.1016/ S0306-4522(00)00110-X. PMID:10869852.
    • (2000) Neuroscience , vol.98 , Issue.3 , pp. 585-598
    • Honore, P.1    Rogers, S.D.2    Schwei, M.J.3    Salak-Johnson, J.L.4    Luger, N.M.5    Sabino, M.C.6
  • 33
    • 23844486685 scopus 로고    scopus 로고
    • Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance
    • doi:10.1158/0008-5472.CAN-04-4267. PMID:16103098
    • Huang, Y., Dai, Z., Barbacioru, C., and Sadee, W. 2005. Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance. Cancer Res. 65(16): 7446-7454. doi:10.1158/0008-5472.CAN-04-4267. PMID:16103098.
    • (2005) Cancer Res , vol.65 , Issue.16 , pp. 7446-7454
    • Huang, Y.1    Dai, Z.2    Barbacioru, C.3    Sadee, W.4
  • 34
    • 0026698060 scopus 로고
    • Oxidized redox state of glutathione in the endoplasmic reticulum
    • doi: 10.1126/science.1523409. PMID:1523409
    • Hwang, C., Sinskey, A.J., and Lodish, H.F. 1992. Oxidized redox state of glutathione in the endoplasmic reticulum. Science, 257(5076): 1496-1502. doi:10.1126/science.1523409. PMID:1523409.
    • (1992) Science , vol.257 , Issue.5076 , pp. 1496-1502
    • Hwang, C.1    Sinskey, A.J.2    Lodish, H.F.3
  • 35
    • 79952857310 scopus 로고    scopus 로고
    • IARC, Available from
    • IARC. 2010. Globocan 2008. Available from http://globocan.iarc.fr/factsheets/populations/factsheet.asp?uno=900.
    • (2010) Globocan 2008
  • 36
    • 0023513624 scopus 로고
    • Regulation of glutathione levels in mouse spleen lymphocytes by transport of cysteine
    • doi:10.1002/jcp.1041330217. PMID:3680392
    • Ishii, T., Sugita, Y., and Bannai, S. 1987. Regulation of glutathione levels in mouse spleen lymphocytes by transport of cysteine. J. Cell. Physiol. 133(2): 330-336. doi:10.1002/jcp.1041330217. PMID:3680392.
    • (1987) J. Cell. Physiol , vol.133 , Issue.2 , pp. 330-336
    • Ishii, T.1    Sugita, Y.2    Bannai, S.3
  • 37
    • 4344582137 scopus 로고    scopus 로고
    • Peripheral glutamate receptors contribute to mechanical hyperalgesia in a neuropathic painmodeloftherat
    • doi:10.1016/j.neuroscience. 2004.06.040. PMID:15450364
    • Jang, J.H., Kim, D.W., Sang Nam, T., Se Paik, K., and Leem, J.W. 2004. Peripheral glutamate receptors contribute to mechanical hyperalgesia in a neuropathic painmodeloftherat. Neuroscience,128(1):169-176. doi:10.1016/j.neuroscience. 2004.06.040. PMID:15450364.
    • (2004) Neuroscience , vol.128 , Issue.1 , pp. 169-176
    • Jang, J.H.1    Kim, D.W.2    Sang, N.T.3    Se Paik, K.4    Leem, J.W.5
  • 39
    • 80054988003 scopus 로고    scopus 로고
    • Preventive or late administration of anti-NGF therapy attenuates tumor-induced nerve sprouting, neuroma formation, and cancer pain
    • doi:10.1016/j.pain.2011.07.020. PMID:21907491
    • Jimenez-Andrade, J.M., Ghilardi, J.R., Castaneda-Corral, G., Kuskowski, M.A., and Mantyh, P.W. 2011. Preventive or late administration of anti-NGF therapy attenuates tumor-induced nerve sprouting, neuroma formation, and cancer pain. Pain, 152(11): 2564-2574. doi:10.1016/j.pain.2011.07.020. PMID:21907491.
    • (2011) Pain , vol.152 , Issue.11 , pp. 2564-2574
    • Jimenez-Andrade, J.M.1    Ghilardi, J.R.2    Castaneda-Corral, G.3    Kuskowski, M.A.4    Mantyh, P.W.5
  • 40
    • 33645468403 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus fusion-entry receptor: Cystine transporter xCT
    • 10.1126/science.1120878., 16574866
    • Kaleeba, J.A., and Berger, E.A. 2006. Kaposi's sarcoma-associated herpesvirus fusion-entry receptor: cystine transporter xCT. Science, 311(5769): 1921-1924. 10.1126/science.1120878. 16574866.
    • (2006) Science , vol.311 , Issue.5769 , pp. 1921-1924
    • Kaleeba, J.A.1    Berger, E.A.2
  • 41
    • 0026637624 scopus 로고
    • A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion
    • doi:10.1016/ 0306-4522(92)90278-A. PMID:1352866
    • Kato, S., Negishi, K., Mawatari, K., and Kuo, C.H. 1992. A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion. Neuroscience, 48(4): 903-914. doi:10.1016/ 0306-4522(92)90278-A. PMID:1352866.
    • (1992) Neuroscience , vol.48 , Issue.4 , pp. 903-914
    • Kato, S.1    Negishi, K.2    Mawatari, K.3    Kuo, C.H.4
  • 42
    • 49349104661 scopus 로고    scopus 로고
    • Blunted cystine-glutamate antiporter function in the nucleus accumbens promotes cocaine-induced drug seeking
    • doi:10.1016/j.neuroscience.2008.06.010. PMID:18601982
    • Kau, K.S., Madayag, A., Mantsch, J.R., Grier, M.D., Abdulhameed, O., and Baker, D.A. 2008. Blunted cystine-glutamate antiporter function in the nucleus accumbens promotes cocaine-induced drug seeking. Neuroscience, 155(2): 530-537. doi:10.1016/j.neuroscience.2008.06.010. PMID:18601982.
    • (2008) Neuroscience , vol.155 , Issue.2 , pp. 530-537
    • Kau, K.S.1    Madayag, A.2    Mantsch, J.R.3    Grier, M.D.4    Abdulhameed, O.5    Baker, D.A.6
  • 43
    • 0035815984 scopus 로고    scopus 로고
    • Human cystine/glutamate transporter: CDNA cloning and upregulation by oxidative stress in glioma cells
    • doi: 10.1016/S0005-2736(01)00338-8. PMID:11406111
    • Kim, J.Y., Kanai, Y., Chairoungdua, A., Cha, S.H., Matsuo, H., Kim, D. K. et al. 2001. Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells. Biochim. Biophys. Acta, 1512(2): 335-344. doi:10.1016/S0005-2736(01)00338-8. PMID:11406111.
    • (2001) Biochim. Biophys. Acta , vol.1512 , Issue.2 , pp. 335-344
    • Kim, J.Y.1    Kanai, Y.2    Chairoungdua, A.3    Cha, S.H.4    Matsuo, H.5    Kim, D.K.6
  • 44
    • 44449147036 scopus 로고    scopus 로고
    • Tumor cell metabolism: Cancer's Achilles' heel
    • doi:10.1016/j.ccr.2008.05.005. PMID: 18538731
    • Kroemer, G., and Pouyssegur, J. 2008. Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell, 13(6): 472-482. doi:10.1016/j.ccr.2008.05.005. PMID: 18538731.
    • (2008) Cancer Cell , vol.13 , Issue.6 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 45
    • 48349114983 scopus 로고    scopus 로고
    • The xccystine/glutamate antiporter: A mediator of pancreatic cancer growth with a role in drug resistance
    • doi:10.1038/sj.bjc.6604485. PMID: 18648370
    • Lo, M., Ling, V., Wang, Y.Z., and Gout, P.W. 2008. The xccystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance. Br. J. Cancer, 99(3): 464-472. doi:10.1038/sj.bjc.6604485. PMID: 18648370.
    • (2008) Br. J. Cancer , vol.99 , Issue.3 , pp. 464-472
    • Lo, M.1    Ling, V.2    Wang, Y.Z.3    Gout, P.W.4
  • 46
    • 47049130315 scopus 로고    scopus 로고
    • The Kyoto protocol of IASP Basic Pain Terminology
    • doi:10.1016/j.pain.2008.04.025. PMID:18583048
    • Loeser, J.D., and Treede, R.D. 2008. The Kyoto protocol of IASP Basic Pain Terminology. Pain, 137(3): 473-477. doi:10.1016/j.pain.2008.04.025. PMID:18583048.
    • (2008) Pain , vol.137 , Issue.3 , pp. 473-477
    • Loeser, J.D.1    Treede, R.D.2
  • 47
    • 0037008424 scopus 로고    scopus 로고
    • Origins of skeletal pain: Sensory and sympathetic innervation of the mouse femur
    • doi:10.1016/S0306-4522(02) 00165-3. PMID:12123694
    • Mach, D.B., Rogers, S.D., Sabino, M.C., Luger, N.M., Schwei, M.J., Pomonis, J.D., et al. 2002. Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur. Neuroscience, 113(1): 155-166. doi:10.1016/S0306-4522(02) 00165-3. PMID:12123694.
    • (2002) Neuroscience , vol.113 , Issue.1 , pp. 155-166
    • Mach, D.B.1    Rogers, S.D.2    Sabino, M.C.3    Luger, N.M.4    Schwei, M.J.5    Pomonis, J.D.6
  • 48
    • 78149280765 scopus 로고    scopus 로고
    • Blockade of nerve sprouting and neuroma formation markedly attenuates the development of late stage cancer pain
    • doi:10.1016/j.neuroscience.2010.08.056. PMID: 20851743
    • Mantyh, W.G., Jimenez-Andrade, J.M., Stake, J.I., Bloom, A.P., Kaczmarska, M.J., Taylor, R.N., et al. 2010. Blockade of nerve sprouting and neuroma formation markedly attenuates the development of late stage cancer pain. Neuroscience, 171(2): 588-598. doi:10.1016/j.neuroscience.2010.08.056. PMID: 20851743.
    • (2010) Neuroscience , vol.171 , Issue.2 , pp. 588-598
    • Mantyh, W.G.1    Jimenez-Andrade, J.M.2    Stake, J.I.3    Bloom, A.P.4    Kaczmarska, M.J.5    Taylor, R.N.6
  • 49
    • 55349114377 scopus 로고    scopus 로고
    • Time-dependent changes in striatal xCT protein expression in hemi-Parkinson rats
    • doi:10.1097/WNR. 0b013e328312181c. PMID:18806690
    • Massie, A., Schallier, A., Mertens, B., Vermoesen, K., Bannai, S., Sato, H., et al. 2008. Time-dependent changes in striatal xCT protein expression in hemi-Parkinson rats. Neuroreport, 19(16): 1589-1592. doi:10.1097/WNR. 0b013e328312181c. PMID:18806690.
    • (2008) Neuroreport , vol.19 , Issue.16 , pp. 1589-1592
    • Massie, A.1    Schallier, A.2    Mertens, B.3    Vermoesen, K.4    Bannai, S.5    Sato, H.6
  • 50
    • 0034064577 scopus 로고    scopus 로고
    • Excitatory amino acid profiles of synovial fluid from patients with arthritis
    • PMID:10743819
    • McNearney, T., Speegle, D., Lawand, N., Lisse, J., and Westlund, K.N. 2000. Excitatory amino acid profiles of synovial fluid from patients with arthritis. J. Rheumatol. 27(3): 739-745. PMID:10743819.
    • (2000) J. Rheumatol , vol.27 , Issue.3 , pp. 739-745
    • McNearney, T.1    Speegle, D.2    Lawand, N.3    Lisse, J.4    Westlund, K.N.5
  • 51
    • 0031056437 scopus 로고    scopus 로고
    • Malignant bone pain: Pathophysiology and treatment
    • doi:10.1016/S0304-3959(96)03267-8. PMID:9060007
    • Mercadante, S. 1997. Malignant bone pain: pathophysiology and treatment. Pain, 69(1-2): 1-18. doi:10.1016/S0304-3959(96)03267-8. PMID:9060007.
    • (1997) Pain , vol.69 , Issue.1-2 , pp. 1-18
    • Mercadante, S.1
  • 52
    • 0033561013 scopus 로고    scopus 로고
    • Pain treatment and outcomes for patients with advanced cancer who receive follow-up care at home
    • doi:10.1002/(SICI)1097-0142(19990415)85:81849::AID-CNCR273.0.CO;2-6. PMID:10223581
    • Mercadante, S. 1999. Pain treatment and outcomes for patients with advanced cancer who receive follow-up care at home. Cancer, 85(8): 1849-1858. doi:10.1002/(SICI)1097-0142(19990415)85:81849::AID-CNCR273.0.CO;2-6. PMID:10223581.
    • (1999) Cancer , vol.85 , Issue.8 , pp. 1849-1858
    • Mercadante, S.1
  • 53
    • 0034882106 scopus 로고    scopus 로고
    • Symptoms during cancer pain treatment following WHO-guidelines: A longitudinal follow-up study of symptom prevalence, severity and etiology
    • doi:10.1016/S0304-3959(01)00324-4. PMID:11514084
    • Meuser, T., Pietruck, C., Radbruch, L., Stute, P., Lehmann, K.A., and Grond, S. 2001. Symptoms during cancer pain treatment following WHO-guidelines: a longitudinal follow-up study of symptom prevalence, severity and etiology. Pain, 93(3): 247-257. doi:10.1016/S0304-3959(01)00324-4. PMID:11514084.
    • (2001) Pain , vol.93 , Issue.3 , pp. 247-257
    • Meuser, T.1    Pietruck, C.2    Radbruch, L.3    Stute, P.4    Lehmann, K.A.5    Grond, S.6
  • 54
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: Causes, consequences and therapeutic opportunities
    • doi:10.1038/nrc867. PMID: 12154351
    • Mundy, G.R. 2002. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat. Rev. Cancer, 2(8): 584-593. doi:10.1038/nrc867. PMID: 12154351.
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.8 , pp. 584-593
    • Mundy, G.R.1
  • 55
    • 0024678458 scopus 로고
    • Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress
    • doi:10.1016/08966273(89)90043-3. PMID:2576375
    • Murphy, T.H., Miyamoto, M., Sastre, A., Schnaar, R.L., and Coyle, J.T. 1989. Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron, 2(6): 1547-1558. doi:10.1016/08966273(89)90043-3. PMID:2576375.
    • (1989) Neuron , vol.2 , Issue.6 , pp. 1547-1558
    • Murphy, T.H.1    Miyamoto, M.2    Sastre, A.3    Schnaar, R.L.4    Coyle, J.T.5
  • 56
    • 33749536383 scopus 로고    scopus 로고
    • Osteoclasts play a part in pain due to the inflammation adjacent to bone
    • doi:10.1016/j.bone.2006.04.033. PMID:16769263
    • Nagae, M., Hiraga, T., Wakabayashi, H., Wang, L., Iwata, K., and Yoneda, T. 2006. Osteoclasts play a part in pain due to the inflammation adjacent to bone. Bone, 39(5): 1107-1115. doi:10.1016/j.bone.2006.04.033. PMID:16769263.
    • (2006) Bone , vol.39 , Issue.5 , pp. 1107-1115
    • Nagae, M.1    Hiraga, T.2    Wakabayashi, H.3    Wang, L.4    Iwata, K.5    Yoneda, T.6
  • 57
    • 0842311704 scopus 로고    scopus 로고
    • Suppression of cystine uptake by sulfasalazine inhibits proliferation of human mammary carcinoma cells
    • PMID: 14981898
    • Narang, V.S., Pauletti, G.M., Gout, P.W., Buckley, D.J., and Buckley, A.R. 2003. Suppression of cystine uptake by sulfasalazine inhibits proliferation of human mammary carcinoma cells. Anticancer Res. 23(6C): 4571-4579. PMID: 14981898.
    • (2003) Anticancer Res , vol.23 , Issue.6 C , pp. 4571-4579
    • Narang, V.S.1    Pauletti, G.M.2    Gout, P.W.3    Buckley, D.J.4    Buckley, A.R.5
  • 58
    • 0032536755 scopus 로고    scopus 로고
    • Formalin-induced release of excitatory amino acids in the skin of the rat hindpaw
    • doi:10.1016/S0006-8993(97)01568-0. PMID:9518591
    • Omote, K., Kawamata, T., Kawamata, M., and Namiki, A. 1998. Formalin-induced release of excitatory amino acids in the skin of the rat hindpaw. Brain Res. 787(1): 161-164. doi:10.1016/S0006-8993(97)01568-0. PMID:9518591.
    • (1998) Brain Res , vol.787 , Issue.1 , pp. 161-164
    • Omote, K.1    Kawamata, T.2    Kawamata, M.3    Namiki, A.4
  • 59
    • 0034659807 scopus 로고    scopus 로고
    • Pathophysiologic interactions in skeletal metastasis
    • doi:10.1002/ 1097-0142(20000615)88:122912::AID-CNCR63.0.CO;2-8. PMID:10898334
    • Orr, F.W., Lee, J., Duivenvoorden, W.C., and Singh, G. 2000. Pathophysiologic interactions in skeletal metastasis. Cancer, 88(12 Suppl.): 2912-2918. doi:10.1002/ 1097-0142(20000615)88:122912::AID-CNCR3.0.CO;2-8. PMID:10898334.
    • (2000) Cancer , vol.88 , Issue.12 SUPPL. , pp. 2912-2918
    • Orr, F.W.1    Lee, J.2    Duivenvoorden, W.C.3    Singh, G.4
  • 60
    • 39849097748 scopus 로고    scopus 로고
    • Redox regulation in the extracellular environment
    • doi:10.1253/circj.72.1. PMID: 18159092
    • Ottaviano, F.G., Handy, D.E., and Loscalzo, J. 2008. Redox regulation in the extracellular environment. Circ. J. 72(1): 1-16. doi:10.1253/circj.72.1. PMID: 18159092.
    • (2008) Circ. J , vol.72 , Issue.1 , pp. 1-16
    • Ottaviano, F.G.1    Handy, D.E.2    Loscalzo, J.3
  • 61
  • 62
    • 0032703983 scopus 로고    scopus 로고
    • Barriers to effective cancer pain management: A review of the literature
    • doi: 10.1016/S0885-3924(99)00097-4. PMID:10584460
    • Pargeon, K.L., and Hailey, B.J. 1999. Barriers to effective cancer pain management: a review of the literature. J. Pain Symptom Manage. 18(5): 358-368. doi:10.1016/S0885-3924(99)00097-4. PMID:10584460.
    • (1999) J. Pain Symptom Manage , vol.18 , Issue.5 , pp. 358-368
    • Pargeon, K.L.1    Hailey, B.J.2
  • 63
    • 0347480436 scopus 로고    scopus 로고
    • Differentiation of substrate and non-substrate inhibitors of transport system xc(-): An obligate exchanger of L-glutamate and L-cystine
    • doi:10.1016/j.neuropharm.2003.08.006. PMID:14680765
    • Patel, S.A., Warren, B.A., Rhoderick, J.F., and Bridges, R.J. 2004. Differentiation of substrate and non-substrate inhibitors of transport system xc(-): an obligate exchanger of L-glutamate and L-cystine. Neuropharmacology, 46(2): 273-284. doi:10.1016/j.neuropharm.2003.08.006. PMID:14680765.
    • (2004) Neuropharmacology , vol.46 , Issue.2 , pp. 273-284
    • Patel, S.A.1    Warren, B.A.2    Rhoderick, J.F.3    Bridges, R.J.4
  • 64
    • 72049130253 scopus 로고    scopus 로고
    • Isoxazole analogues bind the system xctransporter: Structure-activity relationship and pharmacophore model
    • doi:10.1016/j.bmc.2009.11.001. PMID:19932968
    • Patel, S.A., Rajale, T., O'Brien, E., Burkhart, D.J., Nelson, J.K., Twamley, B., et al. 2010. Isoxazole analogues bind the system xctransporter: structure-activity relationship and pharmacophore model. Bioorg. Med. Chem. 18(1): 202-213. doi:10.1016/j.bmc.2009.11.001. PMID:19932968.
    • (2010) Bioorg. Med. Chem , vol.18 , Issue.1 , pp. 202-213
    • Patel, S.A.1    Rajale, T.2    O'Brien, E.3    Burkhart, D.J.4    Nelson, J.K.5    Twamley, B.6
  • 65
    • 0033961684 scopus 로고    scopus 로고
    • Carrier-mediated delivery of metabotrophic glutamate receptor ligands to the central nervous system: Structural tolerance and potential of the L-system amino acid transporter at the blood-brain barrier
    • doi:10. 1097/00004647-200001000-00021. PMID:10616805
    • Reichel, A., Begley, D.J., and Abbott, N.J. 2000. Carrier-mediated delivery of metabotrophic glutamate receptor ligands to the central nervous system: structural tolerance and potential of the L-system amino acid transporter at the blood-brain barrier. J. Cereb. Blood Flow Metab. 20(1): 168-174. doi:10. 1097/00004647-200001000-00021. PMID:10616805.
    • (2000) J. Cereb. Blood Flow Metab , vol.20 , Issue.1 , pp. 168-174
    • Reichel, A.1    Begley, D.J.2    Abbott, N.J.3
  • 66
    • 4143071413 scopus 로고    scopus 로고
    • In vitro and in vivo activity of the nuclear factor-kappaB inhibitor sulfasalazine in human glioblastomas
    • doi: 10.1158/1078-0432.CCR-03-0392. PMID:15328202
    • Robe, P.A., Bentires-Alj, M., Bonif, M., Rogister, B., Deprez, M., Haddada, H., et al. 2004. In vitro and in vivo activity of the nuclear factor-kappaB inhibitor sulfasalazine in human glioblastomas. Clin. Cancer Res. 10(16): 5595-5603. doi:10.1158/1078-0432.CCR-03-0392. PMID:15328202.
    • (2004) Clin. Cancer Res , vol.10 , Issue.16 , pp. 5595-5603
    • Robe, P.A.1    Bentires-Alj, M.2    Bonif, M.3    Rogister, B.4    Deprez, M.5    Haddada, H.6
  • 67
    • 9244234464 scopus 로고    scopus 로고
    • Increase in muscle nociceptive substances and anaerobic metabolism in patients with trapezius myalgia: Microdialysis in rest and during exercise
    • doi:10.1016/j.pain.2004.09.017. PMID:15561388
    • Rosendal, L., Larsson, B., Kristiansen, J., Peolsson, M., Sogaard, K., Kjaer, M., et al. 2004. Increase in muscle nociceptive substances and anaerobic metabolism in patients with trapezius myalgia: microdialysis in rest and during exercise. Pain, 112(3): 324-334. doi:10.1016/j.pain.2004.09.017. PMID:15561388.
    • (2004) Pain , vol.112 , Issue.3 , pp. 324-334
    • Rosendal, L.1    Larsson, B.2    Kristiansen, J.3    Peolsson, M.4    Sogaard, K.5    Kjaer, M.6
  • 68
    • 0242417086 scopus 로고    scopus 로고
    • Bone histology at autopsy and matched bone scintigraphy findings in patients with hormone refractory prostate cancer: The effect of bisphosphonate therapy on bone scintigraphy results
    • doi:10.1023/A:1022627421000. PMID:12705638
    • Roudier, M.P., Vesselle, H., True, L.D., Higano, C.S., Ott, S.M., King, S.H., et al. 2003. Bone histology at autopsy and matched bone scintigraphy findings in patients with hormone refractory prostate cancer: the effect of bisphosphonate therapy on bone scintigraphy results. Clin. Exp. Metastasis, 20(2), 171-180. doi:10.1023/A:1022627421000. PMID:12705638.
    • (2003) Clin. Exp. Metastasis , vol.20 , Issue.2 , pp. 171-180
    • Roudier, M.P.1    Vesselle, H.2    True, L.D.3    Higano, C.S.4    Ott, S.M.5    King, S.H.6
  • 69
    • 0035933192 scopus 로고    scopus 로고
    • Glutamate antagonists limit tumor growth
    • doi:10.1073/pnas. 091113598. PMID:11331750
    • Rzeski, W., Turski, L., and Ikonomidou, C. 2001. Glutamate antagonists limit tumor growth. Proc. Natl. Acad. Sci. U.S.A. 98(11): 6372-6377. doi:10.1073/pnas. 091113598. PMID:11331750.
    • (2001) Proc. Natl. Acad. Sci. U.S.A , vol.98 , Issue.11 , pp. 6372-6377
    • Rzeski, W.1    Turski, L.2    Ikonomidou, C.3
  • 70
    • 15544366136 scopus 로고    scopus 로고
    • Pathophysiology of bone cancer pain
    • PMID:15724942
    • Sabino, M.A., and Mantyh, P.W. 2005. Pathophysiology of bone cancer pain. J. Support. Oncol. 3(1): 15-24. PMID:15724942.
    • (2005) J. Support. Oncol , vol.3 , Issue.1 , pp. 15-24
    • Sabino, M.A.1    Mantyh, P.W.2
  • 72
    • 77950894917 scopus 로고    scopus 로고
    • A by-product of glutathione production in cancer cells may cause disruption in bone metabolic processes
    • Seidlitz, E.P., Sharma, M.K., and Singh, G. 2010a. A by-product of glutathione production in cancer cells may cause disruption in bone metabolic processes. Can. J. Physiol. Pharmacol. 88: 197-203.
    • (2010) Can. J. Physiol. Pharmacol , vol.88 , pp. 197-203
    • Seidlitz, E.P.1    Sharma, M.K.2    Singh, G.3
  • 73
    • 79952196613 scopus 로고    scopus 로고
    • Extracellular glutamate alters mature osteoclast and osteoblast functions
    • doi:10.1139/Y10-070. PMID:20921979
    • Seidlitz, E.P., Sharma, M.K., and Singh, G. 2010b. Extracellular glutamate alters mature osteoclast and osteoblast functions. Can. J. Physiol. Pharmacol. 88(9): 929-936. doi:10.1139/Y10-070. PMID:20921979.
    • (2010) Can. J. Physiol. Pharmacol , vol.88 , Issue.9 , pp. 929-936
    • Seidlitz, E.P.1    Sharma, M.K.2    Singh, G.3
  • 74
    • 72949097827 scopus 로고    scopus 로고
    • Cancer cells release glutamate via the cystine/glutamate antiporter
    • doi:10.1016/j.bbrc.2009.10.168. PMID:19896463
    • Sharma, M.K., Seidlitz, E.P., and Singh, G. 2010. Cancer cells release glutamate via the cystine/glutamate antiporter. Biochem. Biophys. Res. Commun. 391(1): 91-95. doi:10.1016/j.bbrc.2009.10.168. PMID:19896463.
    • (2010) Biochem. Biophys. Res. Commun , vol.391 , Issue.1 , pp. 91-95
    • Sharma, M.K.1    Seidlitz, E.P.2    Singh, G.3
  • 75
    • 80052916095 scopus 로고    scopus 로고
    • Inhibition of xc transporter-mediated cystine uptake by sulfasalazine analogs
    • doi:10.1016/j.bmcl.2011.07. 081. PMID:21889337
    • Shukla, K., Thomas, A.G., Ferraris, D.V., Hin, N., Sattler, R., Alt, J., et al. 2011. Inhibition of xc transporter-mediated cystine uptake by sulfasalazine analogs. Bioorg. Med. Chem. Lett. 21(20): 6184-6187. doi:10.1016/j.bmcl.2011.07. 081. PMID:21889337.
    • (2011) Bioorg. Med. Chem. Lett , vol.21 , Issue.20 , pp. 6184-6187
    • Shukla, K.1    Thomas, A.G.2    Ferraris, D.V.3    Hin, N.4    Sattler, R.5    Alt, J.6
  • 76
    • 51749088109 scopus 로고    scopus 로고
    • The role of glutamate in the regulation of bone mass and architecture
    • Skerry, T.M. 2008. The role of glutamate in the regulation of bone mass and architecture. J. Musculoskelet. Neuronal Interact. 8: 166-173.
    • (2008) J. Musculoskelet. Neuronal Interact , vol.8 , pp. 166-173
    • Skerry, T.M.1
  • 77
    • 0034097586 scopus 로고    scopus 로고
    • Metastatic breast cancer: Clinical course, prognosis and therapy related to the first site of metastasis
    • doi:10.1023/A: 1006308619659. PMID:10832597
    • Solomayer, E.F., Diel, I.J., Meyberg, G.C., Gollan, C., and Bastert, G. 2000. Metastatic breast cancer: clinical course, prognosis and therapy related to the first site of metastasis. Breast Cancer Res. Treat. 59(3): 271-278. doi:10.1023/A: 1006308619659. PMID:10832597.
    • (2000) Breast Cancer Res. Treat , vol.59 , Issue.3 , pp. 271-278
    • Solomayer, E.F.1    Diel, I.J.2    Meyberg, G.C.3    Gollan, C.4    Bastert, G.5
  • 78
    • 0021341544 scopus 로고
    • Transport of cystine in isolated rat hepatocytes in primary culture
    • PMID:6142043
    • Takada, A., and Bannai, S. 1984. Transport of cystine in isolated rat hepatocytes in primary culture. J. Biol. Chem. 259(4): 2441-2445. PMID:6142043.
    • (1984) J. Biol. Chem , vol.259 , Issue.4 , pp. 2441-2445
    • Takada, A.1    Bannai, S.2
  • 79
    • 0034800265 scopus 로고    scopus 로고
    • Glutamate release promotes growth of malignant gliomas
    • doi:10.1038/nm0901-1010. PMID:11533703
    • Takano, T., Lin, J.H., Arcuino, G., Gao, Q., Yang, J., and Nedergaard, M. 2001. Glutamate release promotes growth of malignant gliomas. Nat. Med. 7(9): 1010-1015. doi:10.1038/nm0901-1010. PMID:11533703.
    • (2001) Nat. Med , vol.7 , Issue.9 , pp. 1010-1015
    • Takano, T.1    Lin, J.H.2    Arcuino, G.3    Gao, Q.4    Yang, J.5    Nedergaard, M.6
  • 80
    • 79952115331 scopus 로고    scopus 로고
    • Glutamate preferentially suppresses osteoblastogenesis than adipogenesis through the cystine/glutamate antiporter in mesenchymal stem cells
    • doi:10.1002/jcp.22390. PMID: 20717926
    • Takarada-Iemata, M., Takarada, T., Nakamura, Y., Nakatani, E., Hori, O., and Yoneda, Y. 2011. Glutamate preferentially suppresses osteoblastogenesis than adipogenesis through the cystine/glutamate antiporter in mesenchymal stem cells. J. Cell. Physiol. 226: 652-665. doi:10.1002/jcp.22390. PMID: 20717926.
    • (2011) J. Cell. Physiol , vol.226 , pp. 652-665
    • Takarada-Iemata, M.1    Takarada, T.2    Nakamura, Y.3    Nakatani, E.4    Hori, O.5    Yoneda, Y.6
  • 81
    • 0033305222 scopus 로고    scopus 로고
    • Breast cancer cells interact with osteoblasts to support osteoclast formation
    • doi:10.1210/en.140.10.4451. PMID: 10499498
    • Thomas, R.J., Guise, T.A., Yin, J.J., Elliott, J., Horwood, N.J., Martin, T. J. et al. 1999. Breast cancer cells interact with osteoblasts to support osteoclast formation. Endocrinology, 140: 4451-4458. doi:10.1210/en.140.10.4451. PMID: 10499498.
    • (1999) Endocrinology , vol.140 , pp. 4451-4458
    • Thomas, R.J.1    Guise, T.A.2    Yin, J.J.3    Elliott, J.4    Horwood, N.J.5    Martin, T.J.6
  • 82
    • 1342281232 scopus 로고    scopus 로고
    • CATs and HATs: The SLC7 family of amino acid transporters
    • doi:10.1007/s00424-003-1086-z. PMID:14770310
    • Verrey, F., Closs, E.I., Wagner, C.A., Palacin, M., Endou, H., and Kanai, Y. 2004. CATs and HATs: the SLC7 family of amino acid transporters. Pflugers Arch. 447(5): 532-542. doi:10.1007/s00424-003-1086-z. PMID:14770310.
    • (2004) Pflugers Arch , vol.447 , Issue.5 , pp. 532-542
    • Verrey, F.1    Closs, E.I.2    Wagner, C.A.3    Palacin, M.4    Endou, H.5    Kanai, Y.6
  • 83
    • 0032032469 scopus 로고    scopus 로고
    • Sulfasalazine: A potent and specific inhibitor of nuclear factor kappa B
    • doi:10.1172/JCI992. PMID:9486988
    • Wahl, C., Liptay, S., Adler, G., and Schmid, R.M. 1998. Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B. J. Clin. Invest. 101(5): 1163-1174. doi:10.1172/JCI992. PMID:9486988.
    • (1998) J. Clin. Invest , vol.101 , Issue.5 , pp. 1163-1174
    • Wahl, C.1    Liptay, S.2    Adler, G.3    Schmid, R.M.4
  • 84
    • 0038239858 scopus 로고    scopus 로고
    • Expression of the activity of cystine/glutamate exchange transporter, system x(c)(-), by xCT and rBAT
    • doi:10.1016/S0006-291X(03)00808-8. PMID:12763038
    • Wang, H., Tamba, M., Kimata, M., Sakamoto, K., Bannai, S., and Sato, H. 2003. Expression of the activity of cystine/glutamate exchange transporter, system x(c)(-), by xCT and rBAT. Biochem. Biophys. Res. Commun. 305(3): 611-618. doi:10.1016/S0006-291X(03)00808-8. PMID:12763038.
    • (2003) Biochem. Biophys. Res. Commun , vol.305 , Issue.3 , pp. 611-618
    • Wang, H.1    Tamba, M.2    Kimata, M.3    Sakamoto, K.4    Bannai, S.5    Sato, H.6
  • 85
    • 85006768050 scopus 로고
    • The metabolism of tumors in the body
    • doi:10.1085/jgp.8.6.519. PMID:19872213
    • Warburg, O., Wind, F., and Negelein, E. 1927. The metabolism of tumors in the body. J. Gen. Physiol. 8(6): 519-530. doi:10.1085/jgp.8.6.519. PMID:19872213.
    • (1927) J. Gen. Physiol , vol.8 , Issue.6 , pp. 519-530
    • Warburg, O.1    Wind, F.2    Negelein, E.3
  • 86
    • 0023178836 scopus 로고
    • Induction of cystine transport activity in mouse peritoneal macrophages
    • doi:10.1084/jem. 165.3.628. PMID:2880923
    • Watanabe, H., and Bannai, S. 1987. Induction of cystine transport activity in mouse peritoneal macrophages. J. Exp. Med. 165(3): 628-640. doi:10.1084/jem. 165.3.628. PMID:2880923.
    • (1987) J. Exp. Med , vol.165 , Issue.3 , pp. 628-640
    • Watanabe, H.1    Bannai, S.2
  • 87
    • 0003527864 scopus 로고    scopus 로고
    • WHO, 2nd ed. Geneva: World Health Organization
    • WHO. 1996. Cancer Pain Relief, 2nd ed. Geneva: World Health Organization.
    • (1996) Cancer Pain Relief
  • 88
    • 0033577982 scopus 로고    scopus 로고
    • Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs
    • doi: 10.1056/NEJM199906173402407. PMID:10369853
    • Wolfe, M.M., Lichtenstein, D.R., and Singh, G. 1999. Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs. N. Engl. J. Med. 340(24): 1888-1899. doi:10.1056/NEJM199906173402407. PMID:10369853.
    • (1999) N. Engl. J. Med , vol.340 , Issue.24 , pp. 1888-1899
    • Wolfe, M.M.1    Lichtenstein, D.R.2    Singh, G.3
  • 89
    • 1542376929 scopus 로고    scopus 로고
    • Glutathione metabolism and its implications for health
    • PMID: 14988435
    • Wu, G., Fang, Y.Z., Yang, S., Lupton, J.R., and Turner, N.D. 2004. Glutathione metabolism and its implications for health. J. Nutr. 134(3): 489-492. PMID: 14988435.
    • (2004) J. Nutr , vol.134 , Issue.3 , pp. 489-492
    • Wu, G.1    Fang, Y.Z.2    Yang, S.3    Lupton, J.R.4    Turner, N.D.5
  • 90
    • 38549167914 scopus 로고    scopus 로고
    • Factors affecting survival in breast cancer patients following bone metastasis
    • PMID: 18338493
    • Yavas, O., Hayran, M., and Ozisik, Y. 2007. Factors affecting survival in breast cancer patients following bone metastasis. Tumori, 93(6): 580-586. PMID: 18338493.
    • (2007) Tumori , vol.93 , Issue.6 , pp. 580-586
    • Yavas, O.1    Hayran, M.2    Ozisik, Y.3
  • 91
    • 0033198997 scopus 로고    scopus 로고
    • Glioma cells release excitotoxic concentrations of glutamate
    • PMID:10485487
    • Ye, Z.C., and Sontheimer, H. 1999. Glioma cells release excitotoxic concentrations of glutamate. Cancer Res. 59(17): 4383-4391. PMID:10485487.
    • (1999) Cancer Res , vol.59 , Issue.17 , pp. 4383-4391
    • Ye, Z.C.1    Sontheimer, H.2
  • 92
    • 0033573392 scopus 로고    scopus 로고
    • Compromised glutamate transport in human glioma cells: Reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystineglutamate exchange
    • PMID:10594060
    • Ye, Z.C., Rothstein, J.D., and Sontheimer, H. 1999. Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystineglutamate exchange. J. Neurosci. 19(24): 10767-10777. PMID:10594060.
    • (1999) J. Neurosci , vol.19 , Issue.24 , pp. 10767-10777
    • Ye, Z.C.1    Rothstein, J.D.2    Sontheimer, H.3
  • 93
    • 78650305975 scopus 로고    scopus 로고
    • Involvement of acidic microenvironment in the pathophysiology of cancer-associated bone pain
    • doi:10.1016/j.bone.2010. 07.009. PMID:20637323
    • Yoneda, T., Hata, K., Nakanishi, M., Nagae, M., Nagayama, T., Wakabayashi, H., et al. 2011. Involvement of acidic microenvironment in the pathophysiology of cancer-associated bone pain. Bone, 48(1): 100-105. doi:10.1016/j.bone.2010. 07.009. PMID:20637323.
    • (2011) Bone , vol.48 , Issue.1 , pp. 100-105
    • Yoneda, T.1    Hata, K.2    Nakanishi, M.3    Nagae, M.4    Nagayama, T.5    Wakabayashi, H.6
  • 94
    • 0028848482 scopus 로고
    • Validation of World Health Organization Guidelines for cancer pain relief: A 10-year prospective study
    • doi:10.1016/0304-3959(95)00017-M. PMID: 8577492
    • Zech, D.F., Grond, S., Lynch, J., Hertel, D., and Lehmann, K.A. 1995. Validation of World Health Organization Guidelines for cancer pain relief: a 10-year prospective study. Pain, 63(1): 65-76. doi:10.1016/0304-3959(95)00017-M. PMID: 8577492.
    • (1995) Pain , vol.63 , Issue.1 , pp. 65-76
    • Zech, D.F.1    Grond, S.2    Lynch, J.3    Hertel, D.4    Lehmann, K.A.5
  • 95
    • 9144229151 scopus 로고    scopus 로고
    • Molecular mechanism(s) for UV-B irradiation-induced glutathione depletion in cultured human keratinocytes
    • doi:10.1562/2004-02-26-RA-091.1. PMID: 15244506
    • Zhu, M., and Bowden, G.T. 2004. Molecular mechanism(s) for UV-B irradiation-induced glutathione depletion in cultured human keratinocytes. Photochem. Photobiol. 80(2): 191-196. doi:10.1562/2004-02-26-RA-091.1. PMID: 15244506.
    • (2004) Photochem. Photobiol , vol.80 , Issue.2 , pp. 191-196
    • Zhu, M.1    Bowden, G.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.