Eomesodermin of Atlantic Salmon: An Important Regulator of Cytolytic Gene and Interferon Gamma Expression in Spleen Lymphocytes

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Kumari, Jaya ^a   Bøgwald, Jarl ^a   Dalmo, Roy A ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; COMPLEMENTARY DNA; EOMESODERMIN; GAMMA INTERFERON; GRANZYME A; INTERFERON REGULATORY FACTOR; OCTAMER TRANSCRIPTION FACTOR 1; SMAD PROTEIN; SMALL INTERFERING RNA; STAT PROTEIN; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR FOXO; TRANSCRIPTION FACTOR SP1;

AEROMONAS SALMONICIDA; ARTICLE; ATLANTIC SALMON; BINDING SITE; BRAIN; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOLYSIS; DNA DETERMINATION; GENE CONTROL; GENE LOCATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INFECTIOUS PANCREATIC NECROSIS VIRUS; KIDNEY; LYMPHOCYTE; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARY; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROVOCATION TEST; QUANTITATIVE STUDY; SPLEEN; SPLEEN CELL; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; UBIQUITINATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CLONING, MOLECULAR; CONSENSUS SEQUENCE; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION; GRANZYMES; HUMANS; INTERFERON-GAMMA; LYMPHOCYTES; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PROMOTER REGIONS, GENETIC; SALMO SALAR; SPLEEN; T-BOX DOMAIN PROTEINS;

EID: 84873578379     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055893     Document Type: Article

References (37)

1. Herrmann BG, (1992) Action of the Brachyury gene in mouse embryogenesis. Ciba Foundation symposium 165: 78-86.
2. Naiche LA, Harrelson Z, Kelly RG, Papaioannou VE, (2005) T-box genes in vertebrate development. Annu Rev Genet 39: 219-239.
3. Pearce EL, Mullen AC, Martins GA, Krawczyk CM, Hutchins AS, et al. (2003) Control of effector CD8+ T cell function by the transcription factor eomesodermin. Science 302: 1041-1043.
4. Russ AP, Wattler S, Colledge WH, Aparicio SA, Carlton MB, et al. (2000) Eomesodermin is required for mouse trophoblast development and mesoderm formation. Nature 404: 95-99.
5. Bruce AE, Howley C, Zhou Y, Vickers SL, Silver LM, et al. (2003) The maternally expressed zebrafish T-box gene eomesodermin regulates organizer formation. Development 130: 5503-5517.
6. Bruce AE, Howley C, Dixon Fox M, Ho RK, (2005) T-box gene eomesodermin and the homeobox-containing Mix/Bix gene mtx2 regulate epiboly movements in the zebrafish. Dev Dyn 233: 105-114.
7. Bjornson CR, Griffin K, Farr GH 3rd, Terashima A, Himeda C, et al (2005) Eomesodermin is a localized maternal determinant required for endoderm induction in zebrafish. Dev Cell 9: 523-533.
8. Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, et al. (2000) A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100: 655-669.
9. Narayanan S, Silva R, Peruzzi G, Alvarez Y, Simhadri VR, et al. (2010) Human Th1 cells that express CD300a are polyfunctional and after stimulation up-regulate the T-box transcription factor eomesodermin. PLoS ONE 5: e10636.
10. Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, et al. (2005) Effector and memory CD8 T cell fate coupled by T-bet and eomesodermin. Nat Immunol 6: 1236-1244.
11. He W, Hao J, Dong S, Gao Y, Tao J, et al. (2010) Naturally activated Vγ4 γδ T cells play a protective role in tumor immunity through expression of eomesodermin. J Immunol 185: 126-133.
12. Atreya I, Schimanski CC, Becker C, Wirtz S, Dornhoff H, et al. (2007) The T-box transcription factor eomesodermin controls CD8 T cell activity and lymph node metastasis in human colorectal cancer. Gut 56: 1572-1578.
13. Zhu Y, Ju S, Chen E, Dai S, Li C, et al. (2010) T-bet and eomesodermin are required for adaptive immunity against cancer. J Immunol 184: 101.27.
14. Glimcher LH, Townsend MJ, Sullivan BM, Lord GM, (2004) Recent developments in the transcriptional regulation of cytolytic effector cells. Nat Rev Immunol 4: 900-911.
15. Takizawa F, Araki K, Ito K, Moritomo T, Nakanishi T, (2007) Expression analysis of two eomesodermin homologues in zebrafish lymphoid tissues and cells. Mol Immunol 44: 2324-2331.
16. Finn RD, Tate J, Mistry J, Coggill PC, Sammut SJ, et al. (2008) The Pfam protein families database. Nuc Acids Res 36: D281-D288.
17. Campanella JJ, Bitincka L, Smalley J, (2003) MatGAT: an application that generates similarity/identity matrices using protein or DNA sequences. BMC Bioinformatics 4: 29.
18. Tamura K, Dudley J, Nei M, Kumar S, (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0. Mol Biol Evol 24: 1596-1599.
19. Cartharius K, Frech K, Grote K, Klocke B, Haltmeier M, et al. (2005) MatInspector and beyond: promoter analysis based on transcription factor binding sites. Bioinformatics 21: 2933-2942.
20. Kumari J, Bogwald J, Dalmo RA, (2009) Transcription factor GATA-3 in Atlantic salmon (Salmo salar): Molecular characterization, promoter activity and expression analysis. Mol Immunol 46: 3099-3107.
21. Ryan K, Garrett N, Bourillot P, Stennard F, Gurdon JB, (2000) The Xenopus eomesodermin promoter and its concentration-dependent response to activin. Mech Dev 94: 133-146.
22. Rao RR, Li Q, Gubbels Bupp MR, Shrikant PA, (2012) Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell Differentiation. Immunity 36: 374-387.
23. Sever-Chroneos Z, Bachurski CJ, Yan C, Whitsett JA, (1999) Regulation of mouse SP-B gene promoter by AP-1 family members. Am J Physiol 277: L79-L88.
24. Takimoto M, Quinn JP, Farina AR, Staudt LM, Levens D, (1989) fos/jun and octamer-binding protein interact with a common site in a negative element of the human c-myc gene. J Biol Chem 264: 8992-8999.
25. Kim MK, Lesoon-Wood LA, Weintraub BD, Chung JH, (1996) A soluble transcription factor, Oct-1, is also found in the insoluble nuclear matrix and possesses silencing activity in its alanine-rich domain. Mol Cell Biol 16: 4366-4377.
26. Wyllie DH, Kiss-Toth E, Visintin A, Smith SC, Boussouf S, et al. (2000) Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses. J Immunol 165: 7125-7132.
27. Stark GR, Kerr IM, Williams BR, Silverman RH, Schreiber RD, (1998) How cells respond to interferons. Annu Rev Biochem 67: 227-264.
28. Robertsen B, Bergan V, Røkenes T, Larsen R, Albuquerque A, (2003) Atlantic salmon interferon genes: cloning, sequence analysis, expression, and biological activity. J Interferon Cytokine Res 23: 601-612.
29. Bogdan C, Mattner J, Schleicher U, (2004) The role of type I interferons in non-viral infections. Immunol Rev 202: 32-48.
30. Klimpel GR, Infante AJ, Patterson J, Hess CB, Asuncion M, (1990) Virus-induced interferon alpha/beta (IFN-alpha/beta) production by T cells and by Th1 and Th2 helper T cell clones: a study of the immunoregulatory actions of IFN-gamma versus IFN-alpha/beta on functions of different T-cell populations. Cell Immunol 128: 603-618.
31. Zhu Y, Ju S, Chen E, Dai S, Li C, et al. (2010) T-bet and eomesodermin are required for T cell-mediated antitumor immune responses. J Immunol 185: 3174-3183.
32. Eshima K, Chiba S, Suzuki H, Kokubo K, Kobayashi H, et al. (2012) Ectopic expression of a T-box transcription factor, eomesodermin, renders CD4(+) Th cells cytotoxic by activating both perforin- and FasL-pathways. Immunol Lett 144: 7-15.
33. Pipkin ME, Rao A, Lichtenheld MG, (2010) The transcriptional control of the perforin locus. Immunol Rev 235: 55-72.
34. Toda H, Shibasaki Y, Koike T, Ohtani M, Takizawa F, et al. (2009) Alloantigen-specific killing is mediated by CD8-positive T cells in fish. Dev Comp Immunol 33: 646-652.
35. Zhou H, Stuge TB, Miller NW, Bengten E, Naftel JP, et al. (2001) Heterogeneity of Channel catfish CTL with respect to target recognition and cytotoxic mechanisms employed. J Immunol 167: 1325-1332.
36. Fischer U, Utke K, Ototake M, Dijkstra JM, Köllner B, (2003) Adaptive cell-mediated cytotoxicity against allogeneic targets by CD8-positive lymphocytes of rainbow trout (Oncorhynchus mykiss). Dev Comp Immunol 27: 323-337.
37. Utke K, Bergmann S, Lorenzen N, Köllner B, Ototake M, et al. (2007) Cell-mediated cytotoxicity in rainbow trout, Oncorhynchus mykiss, infected with viral haemorrhagic septicaemia virus. Fish Shellfish Immunol 22: 182-196.