-
1
-
-
33645050104
-
Cytochrome P450s and other enzymes in drug metabolism and toxicity
-
Guengerich F. Cytochrome P450s and other enzymes in drug metabolism and toxicity. AAPS J 2006; 8:E101-E111.
-
(2006)
AAPS J
, vol.8
-
-
Guengerich, F.1
-
2
-
-
0035104516
-
20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids and blood pressure
-
McGiff JC, Quilley J. 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids and blood pressure. Hypertension 2001; 10:231-237.
-
(2001)
Hypertension
, vol.10
, pp. 231-237
-
-
McGiff, J.C.1
Quilley, J.2
-
3
-
-
0036080081
-
P450 metabolites of arachidonic acid in the control of cardiovascular function
-
Roman RJ. P450 metabolites of arachidonic acid in the control of cardiovascular function. Physiol Rev 2002; 82:131-185.
-
(2002)
Physiol Rev
, vol.82
, pp. 131-185
-
-
Roman, R.J.1
-
4
-
-
33745797993
-
Eicosanoids and renal vascular function in diseases
-
Imig JD. Eicosanoids and renal vascular function in diseases. Clin Sci 2006; 111:21-34.
-
(2006)
Clin Sci
, vol.111
, pp. 21-34
-
-
Imig, J.D.1
-
5
-
-
34548480936
-
Roles of the cytochrome P450 arachidonic acid monooxygenases in the control of systemic blood pressure and experimental hypertension
-
Capdevila JH, Falck JR, Imig JD. Roles of the cytochrome P450 arachidonic acid monooxygenases in the control of systemic blood pressure and experimental hypertension. Kidney Int 2007; 72:683-689.
-
(2007)
Kidney Int
, vol.72
, pp. 683-689
-
-
Capdevila, J.H.1
Falck, J.R.2
Imig, J.D.3
-
6
-
-
0027996820
-
Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet
-
Makita K, Takahashi K, Karara A, et al. Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet. J Clin Invest 1994; 94:2414-2420.
-
(1994)
J Clin Invest
, vol.94
, pp. 2414-2420
-
-
Makita, K.1
Takahashi, K.2
Karara, A.3
-
7
-
-
0034802185
-
Identification and localization of five CYP2Cs in murine extrahepatic tissues and their metabolism of arachidonic acid to regio-and stereoselective products
-
Tsao CC, Coulter SJ, Chien A, et al. Identification and localization of five CYP2Cs in murine extrahepatic tissues and their metabolism of arachidonic acid to regio-and stereoselective products. J Pharmacol Exp Ther 2001; 299:39-47.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 39-47
-
-
Tsao, C.C.1
Coulter, S.J.2
Chien, A.3
-
8
-
-
4243182600
-
CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products
-
DeLozier TC, Tsao CC, Coulter SJ, et al. CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products. J Pharmacol Exp Ther 2004; 310:845-854.
-
(2004)
J Pharmacol Exp Ther
, vol.310
, pp. 845-854
-
-
Delozier, T.C.1
Tsao, C.C.2
Coulter, S.J.3
-
9
-
-
33745197144
-
Salt sensitive hypertension is associated with a dysfunctional Cyp4a10 gene and kidney epithelial sodium channel
-
Nakagawa K, Holla VR, Wei Y, et al. Salt sensitive hypertension is associated with a dysfunctional Cyp4a10 gene and kidney epithelial sodium channel. J Clin Invest 2006; 116:1696-1702.
-
(2006)
J Clin Invest
, vol.116
, pp. 1696-1702
-
-
Nakagawa, K.1
Holla, V.R.2
Wei, Y.3
-
10
-
-
0029825785
-
CYP2J subfamily P450s in the lung: Expression, localization, and potential functional significance
-
Zeldin DC, Foley J, Ma J, et al. CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance. Mol Pharmacol 1996; 50:1111-1117.
-
(1996)
Mol Pharmacol
, vol.50
, pp. 1111-1117
-
-
Zeldin, D.C.1
Foley, J.2
Ma, J.3
-
11
-
-
0034635521
-
Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney
-
Lasker JM, Chen WB, Wolf I, et al. Formation of 20- hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. J Biol Chem 2000; 275:4118-4126.
-
(2000)
J Biol Chem
, vol.275
, pp. 4118-4126
-
-
Lasker, J.M.1
Chen, W.B.2
Wolf, I.3
-
12
-
-
57349108805
-
Increased blood pressure in mice lacking cytochrome P450 2J5
-
Athirakul K, Bradbury JA, Graves JP, et al. Increased blood pressure in mice lacking cytochrome P450 2J5. FASEB J 2008; 22:4096-4108.
-
(2008)
FASEB J
, vol.22
, pp. 4096-4108
-
-
Athirakul, K.1
Bradbury, J.A.2
Graves, J.P.3
-
13
-
-
10344261424
-
Arachidonic acid inhibits epithelial Na channel via cytochrome P450 (CYP) epoxygenase-dependent metabolic pathways
-
Wei Y, Lin DH, Kemp R, et al. Arachidonic acid inhibits epithelial Na channel via cytochrome P450 (CYP) epoxygenase-dependent metabolic pathways. J Gen Physiol 2004; 124:719-727.
-
(2004)
J Gen Physiol
, vol.124
, pp. 719-727
-
-
Wei, Y.1
Lin, D.H.2
Kemp, R.3
-
14
-
-
77957860942
-
High potassium intake enhances the inhibitory effect of 11,12-EET on ENaC
-
Sun P, Lin DH, Yue P, et al. High potassium intake enhances the inhibitory effect of 11,12-EET on ENaC. J Am Soc Nephrol 2010; 21:1667-1677.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1667-1677
-
-
Sun, P.1
Lin, D.H.2
Yue, P.3
-
15
-
-
33845350002
-
Low Na intake suppresses expression of CYP2C23 and arachidonic acid-induced inhibition of ENaC
-
Sun P, Lin DH, Wang T, et al. Low Na intake suppresses expression of CYP2C23 and arachidonic acid-induced inhibition of ENaC. Am J Physiol Renal Physiol 2006; 291:1192-1200.
-
(2006)
Am J Physiol Renal Physiol
, vol.291
, pp. 1192-1200
-
-
Sun, P.1
Lin, D.H.2
Wang, T.3
-
16
-
-
80052410373
-
Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (EnaC)
-
Pavlov TS, Ilatovskaya DV, Levchenko V, et al. Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC). Am J Physiol Renal Physiol 2011; 301:F672-F681.
-
(2011)
Am J Physiol Renal Physiol
, vol.301
-
-
Pavlov, T.S.1
Ilatovskaya, D.V.2
Levchenko, V.3
-
17
-
-
0029975139
-
Sodium intake markedly alters renal interstitial fluid adenosine
-
Siragy HM, Linden J. Sodium intake markedly alters renal interstitial fluid adenosine. Hypertension 1996; 27:404-407.
-
(1996)
Hypertension
, vol.27
, pp. 404-407
-
-
Siragy, H.M.1
Linden, J.2
-
18
-
-
62149130775
-
Epoxyeicosatrienoic acid (EET) activates the Ca2\+-dependent big conductance K channel in the cortical collecting duct
-
Sun P, Liu W, Lin DH, et al. Epoxyeicosatrienoic acid (EET) activates the Ca2\+-dependent big conductance K channel in the cortical collecting duct. J Am Soc Nephrol 2009; 20:513-523.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 513-523
-
-
Sun, P.1
Liu, W.2
Lin, D.H.3
-
19
-
-
48249157878
-
Arachidonic acid inhibits basolateral K channels in the cortical collecting duct via cytochrome P-450 epoxygenasedependent metabolic pathways
-
Wang Z, Wei Y, Falck JR, et al. Arachidonic acid inhibits basolateral K channels in the cortical collecting duct via cytochrome P-450 epoxygenasedependent metabolic pathways. Am J Physiol Renal Physiol 2008; 294:F1441-F1447.
-
(2008)
Am J Physiol Renal Physiol
, vol.294
-
-
Wang, Z.1
Wei, Y.2
Falck, J.R.3
-
20
-
-
3142548950
-
Developmental regulation of expression of renal potassium secretory channels
-
Satlin LM. Developmental regulation of expression of renal potassium secretory channels. Curr Opin Nephrol Hypertens 2004; 13:445-450.
-
(2004)
Curr Opin Nephrol Hypertens
, vol.13
, pp. 445-450
-
-
Satlin, L.M.1
-
21
-
-
84864487205
-
Role of the adenosine2A receptor-epoxyeicosatrienoic acid pathway in the development of salt-sensitive hypertension
-
Carroll MA. Role of the adenosine2A receptor-epoxyeicosatrienoic acid pathway in the development of salt-sensitive hypertension. Prostaglandins Other Lipid Mediat 2012; 98:39-47.
-
(2012)
Prostaglandins Other Lipid Mediat
, vol.98
, pp. 39-47
-
-
Carroll, M.A.1
-
22
-
-
0034961040
-
Epoxygenase metabolites contribute to nitric oxide-independent afferent arteriolar vasodilation in response to bradykinin
-
Imig JD, Falck JR, Wei S, et al. Epoxygenase metabolites contribute to nitric oxide-independent afferent arteriolar vasodilation in response to bradykinin. J Vasc Res 2001; 38:247-255.
-
(2001)
J Vasc Res
, vol.38
, pp. 247-255
-
-
Imig, J.D.1
Falck, J.R.2
Wei, S.3
-
23
-
-
38949115541
-
Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2 \+-activated K\+ channels
-
Imig JD, Dimitropoulou C, Reddy DS, et al. Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2 \+-activated K\+ channels. Microcirculation 2008; 15:137-150.
-
(2008)
Microcirculation
, vol.15
, pp. 137-150
-
-
Imig, J.D.1
Dimitropoulou, C.2
Reddy, D.S.3
-
24
-
-
0035896535
-
Alternative splicing switches potassium channel sensitivity to protein phosphorylation
-
Tian L, Duncan RR, Hammond MSL, et al. Alternative splicing switches potassium channel sensitivity to protein phosphorylation. J Biol Chem 2001; 276:7717-7720.
-
(2001)
J Biol Chem
, vol.276
, pp. 7717-7720
-
-
Tian, L.1
Duncan, R.R.2
Hammond, M.S.L.3
-
25
-
-
84866359743
-
Palmitoylation and membrane association of the stress axis regulated insert (STREX) controls BK channel regulation by protein kinase C
-
Zhou X, Wulfsen I, Korth M, et al. Palmitoylation and membrane association of the stress axis regulated insert (STREX) controls BK channel regulation by protein kinase C. J Biol Chem 2012; 287:32161-32171.
-
(2012)
J Biol Chem
, vol.287
, pp. 32161-32171
-
-
Zhou, X.1
Wulfsen, I.2
Korth, M.3
-
26
-
-
0035942194
-
Alterations in the regulation of androgensensitive Cyp 4a monooxygenases cause hypertension
-
Holla VR, Adas F, Imig JD, et al. Alterations in the regulation of androgensensitive Cyp 4a monooxygenases cause hypertension. Proc Natl Acad Sci USA 2001; 98:5211-5216.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5211-5216
-
-
Holla, V.R.1
Adas, F.2
Imig, J.D.3
-
27
-
-
0033580922
-
Molecular cloning, enzymatic characterization, developmental expression, and cellular localization of a mouse cytochrome P450 highly expressed in kidney
-
Ma J, Qu W, Scarborough PE, et al. Molecular cloning, enzymatic characterization, developmental expression, and cellular localization of a mouse cytochrome P450 highly expressed in kidney. J Biol Chem 1999; 274:17777-17788.
-
(1999)
J Biol Chem
, vol.274
, pp. 17777-17788
-
-
Ma, J.1
Qu, W.2
Scarborough, P.E.3
-
28
-
-
84856251792
-
Cyp2c44 epoxygenase is essential for preventing the renal sodium absorption during increasing dietary potassium intake
-
Sun P, Antoun J, Lin DH, et al. Cyp2c44 epoxygenase is essential for preventing the renal sodium absorption during increasing dietary potassium intake. Hypertension 2012; 59:339-347.
-
(2012)
Hypertension
, vol.59
, pp. 339-347
-
-
Sun, P.1
Antoun, J.2
Lin, D.H.3
-
29
-
-
0141997292
-
Salt-sensitive hypertension after exposure to angiotensin is associated with inability to upregulate renal epoxygenases
-
Zhao X, Pollock DM, Zeldin DC, et al. Salt-sensitive hypertension after exposure to angiotensin is associated with inability to upregulate renal epoxygenases. Hypertension 2003; 42:775-780.
-
(2003)
Hypertension
, vol.42
, pp. 775-780
-
-
Zhao, X.1
Pollock, D.M.2
Zeldin, D.C.3
-
30
-
-
33644989494
-
Tumor necrosis factor {alpha} blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension
-
Elmarakby AA, Quigley JE, Pollock DM, et al. Tumor necrosis factor {alpha} blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension. Hypertension 2006; 47:557-562.
-
(2006)
Hypertension
, vol.47
, pp. 557-562
-
-
Elmarakby, A.A.1
Quigley, J.E.2
Pollock, D.M.3
-
31
-
-
0022517033
-
Mechanisms of aldosterone action in tight epithelia
-
Garty H. Mechanisms of aldosterone action in tight epithelia. J Membrane Biol 1986; 90:193-205.
-
(1986)
J Membrane Biol
, vol.90
, pp. 193-205
-
-
Garty, H.1
-
32
-
-
0019614751
-
Short-term effect of aldosterone on Na-K-ATPase in single nephron segments
-
Doucet A, Katz AI. Short-term effect of aldosterone on Na-K-ATPase in single nephron segments. Am J Physiol 1981; 241:273-278.
-
(1981)
Am J Physiol
, vol.241
, pp. 273-278
-
-
Doucet, A.1
Katz, A.I.2
-
33
-
-
0026586125
-
Regulation of apical membrane Na and K channels in rat renal collecting tubules by aldosterone
-
Palmer LG, Frindt G. Regulation of apical membrane Na and K channels in rat renal collecting tubules by aldosterone. Semin Nephrol 1992; 12:37-43.
-
(1992)
Semin Nephrol
, vol.12
, pp. 37-43
-
-
Palmer, L.G.1
Frindt, G.2
-
34
-
-
77957831701
-
Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertensioninduced renal injury in mice
-
Lee CR, Imig JD, Edin ML, et al. Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertensioninduced renal injury in mice. FASEB J 2010; 24:3770-3781.
-
(2010)
FASEB J
, vol.24
, pp. 3770-3781
-
-
Lee, C.R.1
Imig, J.D.2
Edin, M.L.3
-
35
-
-
0030923112
-
Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes
-
Wu S, Chen W, Murphy E, et al. Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes. J Biol Chem 1997; 272:12551-12559.
-
(1997)
J Biol Chem
, vol.272
, pp. 12551-12559
-
-
Wu, S.1
Chen, W.2
Murphy, E.3
-
36
-
-
76749111911
-
Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases
-
Zordoky BNM, El-Kadi AOS. Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases. Pharmacol Ther 2010; 125:446-463.
-
(2010)
Pharmacol Ther
, vol.125
, pp. 446-463
-
-
Zordoky, B.N.M.1
El-Kadi, A.O.S.2
-
37
-
-
84875214071
-
Epoxyeicosatrienoic acid pathway in human health and diseases
-
Epub ahead of print
-
Bellien J, Joannides R. Epoxyeicosatrienoic acid pathway in human health and diseases. J Cardiovasc Pharmacol 2012. [Epub ahead of print]
-
(2012)
J Cardiovasc Pharmacol
-
-
Bellien, J.1
Joannides, R.2
-
38
-
-
0034791777
-
Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid
-
Dai D, Zeldin DC, Blaisdell JA, et al. Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid. Pharmacogenetics 2001; 11:597-607.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 597-607
-
-
Dai, D.1
Zeldin, D.C.2
Blaisdell, J.A.3
-
39
-
-
85047278388
-
Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension
-
King LM, Gainer JV, David GL, et al. Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension. Pharmacogenet Genomics 2005; 15:7-13.
-
(2005)
Pharmacogenet Genomics
, vol.15
, pp. 7-13
-
-
King, L.M.1
Gainer, J.V.2
David, G.L.3
-
40
-
-
4444238679
-
CYP2C9 allele variants in Chinese hypertension patients and healthy controls
-
Yu BN, Luo CH, Wang D, et al. CYP2C9 allele variants in Chinese hypertension patients and healthy controls. Clin Chim Acta 2004; 348: 57-61.
-
(2004)
Clin Chim Acta
, vol.348
, pp. 57-61
-
-
Yu, B.N.1
Luo, C.H.2
Wang, D.3
|