1-Oxoeudesm-11(13)-eno-12,8a-lactone induces G 2/M arrest and apoptosis of human glioblastoma cells in vitro

Acta Pharmacologica Sinica

Volumn 34, Issue 2, 2013, Pages 271-281

  Liu, Shan Shan ^a,b   Wang, Yan Feng ^b   Ma, Li Sha ^a   Zheng, Bei Bei ^a   Li, Lin ^a   Xie, Wei Dong ^a   Li, Xia ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

1 oxoeudesm 11(13) eno 12,8a lactone; apoptosis; Aster himalaicus; cell cycle arrest; DNA damage; malignant glioma; p53; PFT

Indexed keywords

1 OXOEUDESM 11(13) ENO 12,8A LACTONE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR 1; HISTONE H2AX; MESSENGER RNA; PROTEIN P53; SESQUITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; G2 PHASE CELL CYCLE CHECKPOINT; GLIOBLASTOMA; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; ASTER PLANT; BRAIN NEOPLASMS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HUMANS; SESQUITERPENES, EUDESMANE; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84873531713     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2012.137     Document Type: Article

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