Dihydroptychantol A, a macrocyclic bisbibenzyl derivative, induces autophagy and following apoptosis associated with p53 pathway in human osteosarcoma U2OS cells

Toxicology and Applied Pharmacology

Volumn 251, Issue 2, 2011, Pages 146-154

  Li, Xia ^a,b   Wu, William K K ^c   Sun, Bin ^a   Cui, Min ^b   Liu, Shanshan ^b   Gao, Jian ^a   Lou, Hongxiang ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apoptosis; Autophagy; Dihydroptychantol A; P53; U2OS cells

Indexed keywords

3 METHYLADENINE; BIBENZYL DERIVATIVE; CYCLIN B1; DIHYDROPTYCHANTOL A; LC3 II; PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL NUCLEUS MEMBRANE; CELL PROTECTION; CELL STRAIN U2OS; CELL STRUCTURE; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; GENE TARGETING; HUMAN; HUMAN CELL; OSTEOSARCOMA; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

ASTERELLA;

EID: 79851515032     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.12.007     Document Type: Article

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