Spatial patterning of endothelium modulates cell morphology, adhesiveness and transcriptional signature

Biomaterials

Volumn 34, Issue 12, 2013, Pages 2928-2937

  Huang, Ngan F ^a,b   Lai, Edwina S ^c   Ribeiro, Alexandre J S ^c   Pan, Stephen ^a   Pruitt, Beth L ^c   Fuller, Gerald G ^c   Cooke, John P ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c Stanford University   (United States)

Author keywords

Cell morphology; Endothelium; Micropatterning; Monocyte; Nanotopography; Vascular graft

Indexed keywords

CELL MORPHOLOGY; ENDOTHELIUM; MICRO PATTERNING; MONOCYTE; NANOTOPOGRAPHIES; VASCULAR GRAFTS;

ADHESION; BLOOD VESSELS; BODY FLUIDS; ENDOTHELIAL CELLS; GENE EXPRESSION; GRAFTS; NANOTECHNOLOGY; SHEAR STRESS;

MORPHOLOGY;

CELL ADHESION MOLECULE; CHEMOKINE; DIMETICONE;

ARTICLE; CELL ADHESION; CELL FUNCTION; CELL STRUCTURE; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; ENDOTHELIUM CELL; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; MONOCYTE; MORPHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; SHEAR STRESS; THROMBOCYTE; THROMBOCYTE ADHESION;

CELL ADHESION; CELLS, CULTURED; COLLAGEN; ENDOTHELIUM, VASCULAR; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TRANSCRIPTION, GENETIC;

EID: 84873473274     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.01.017     Document Type: Article

References (53)

1. Roger V.L., Go A.S., Lloyd-Jones D.M., Adams R.J., Berry J.D., Brown T.M., et al. Heart disease and stroke statistics: 2011 update. Circulation 2011, 123(4):e18-e209.
2. Vartanian K.B., Berny M.A., McCarty O.J.T., Hanson S.R., Hinds M.T. Cytoskeletal structure regulates endothelial cell immunogenicity independent of fluid shear stress. Am J Physiol Cell Physiol 2010, 298(2):C333-C341.
3. Businaro R., Tagliani A., Buttari B., Profumo E., Ippoliti F., Di Cristofano C., et al. Cellular and molecular players in the atherosclerotic plaque progression. Ann N Y Acad Sci 2012, 1262:134-141.
4. Gerszten R.E., Lim Y.C., Ding H.T., Snapp K., Kansas G., Dichek D.A., et al. Adhesion of monocytes to vascular cell adhesion molecule-1-transduced human endothelial cells: implications for atherogenesis. Circ Res 1998, 82(8):871-878.
5. Gawaz M., Neumann F.J., Dickfeld T., Koch W., Laugwitz K.L., Adelsberger H., et al. Activated platelets induce monocyte chemotactic protein-1 secretion and surface expression of intercellular adhesion molecule-1 on endothelial cells. Circulation 1998, 98(12):1164-1171.
6. Gerszten R.E., Garcia-Zepeda E.A., Lim Y.C., Yoshida M., Ding H.A., Gimbrone M.A., et al. Mcp-1 and il-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature 1999, 398(6729):718-723.
7. Cooke J.P. Flow, no, and atherogenesis. Proc Natl Acad Sci U S A 2003, 100(3):768-770.
8. Yim E.K.F., Reano R.M., Pang S.W., Yee A.F., Chen C.S., Leong K.W. Nanopattern-induced changes in morphology and motility of smooth muscle cells. Biomaterials 2005, 26:5405-5413.
9. Curtis A., Wilkinson C. Nanotechniques and approaches in biotechnology. Mater Today 2001, 4(3):22-28.
10. Flemming R.G., Murphy C.J., Abrams G.A., Goodman S.L., Nealey P.F. Effects of synthetic micro- and nano-structured surfaces on cell behavior. Biomaterials 1999, 20(6):573-588.
11. Wilkinson C.D.W. Nanostructures in biology. Microelectron Eng 1995, 27(1-4):61-65.
12. Dalby M.J., Gadegaard N., Riehle M.O., Wilkinson C.D., Curtis A.S. Investigating filopodia sensing using arrays of defined nano-pits down to 35 nm diameter in size. Int J Biochem Cell Biol 2004, 36(10):2005-2015.
13. Dalby M.J., Riehle M.O., Johnstone H., Affrossman S., Curtis A.S. Investigating the limits of filopodial sensing: a brief report using SEM to image the interaction between 10 nm high nano-topography and fibroblast filopodia. Cell Biol Int 2004, 28(3):229-236.
14. Dalby M.J., Yarwood S.J., Riehle M.O., Johnstone H.J., Affrossman S., Curtis A.S. Increasing fibroblast response to materials using nanotopography: morphological and genetic measurements of cell response to 13-nm-high polymer demixed islands. Exp Cell Res 2002, 276(1):1-9.
15. Wojciak-Stothard B., Curtis A., Monaghan W., Macdonald K., Wilkinson C. Guidance and activation of murine macrophages by nanometric scale topography. Exp Cell Res 1996, 223(2):426-435.
16. Wojciak-Stothard B., Curtis A.S., Monaghan W., McGrath M., Sommer I., Wilkinson C.D. Role of the cytoskeleton in the reaction of fibroblasts to multiple grooved substrata. Cell Motil Cytoskeleton 1995, 31(2):147-158.
17. Corey J.M., Feldman E.L. Substrate patterning: an emerging technology for the study of neuronal behavior. Exp Neurol 2003, 184(Suppl. 1):S89-S96.
18. Miller D.C., Thapa A., Haberstroh K.M., Webster T.J. Endothelial and vascular smooth muscle cell function on poly(lactic-co-glycolic acid) with nano-structured surface features. Biomaterials 2004, 25(1):53-61.
19. Thakar R.G., Ho F., Huang N.F., Liepmann D., Li S. Regulation of vascular smooth muscle cells by micropatterning. Biochem Biophys Res Commun 2003, 307(4):883-890.
20. Lauffenburger D.A., Horwitz A.F. Cell migration: a physically integrated molecular process. Cell 1996, 84(3):359-369.
21. Li S., Bhatia S., Hu Y.-L., Shiu Y.-T., Li Y.-S., Usami S., et al. Effects of morphological patterning on endothelial cell migration. Biorheology 2001, 38:101-108.
22. Liliensiek S.J., Wood J.A., Yong J., Auerbach R., Nealey P.F., Murphy C.J. Modulation of human vascular endothelial cell behaviors by nanotopographic cues. Biomaterials 2010, 31(20):5418-5426.
23. Junkin M., Wong P.K. Probing cell migration in confined environments by plasma lithography. Biomaterials 2011, 32(7):1848-1855.
24. Uttayarat P., Chen M., Li M., Allen F.D., Composto R.J., Lelkes P.I. Microtopography and flow modulate the direction of endothelial cell migration. Am J Physiol Heart Circ Physiol 2008, 294(2):H1027-H1035.
25. Zorlutuna P., Rong Z., Vadgama P., Hasirci V. Influence of nanopatterns on endothelial cell adhesion: enhanced cell retention under shear stress. Acta Biomater 2009, 5(7):2451-2459.
26. Slater J.H., Frey W. Nanopatterning of fibronectin and the influence of integrin clustering on endothelial cell spreading and proliferation. J Biomed Mater Res A 2008, 87A(1):176-195.
27. Qin D., Xia Y., Whitesides G.M. Soft lithography for micro- and nanoscale patterning. Nat Protocol 2010, 5(3):491-502.
28. Hovis J.S., Boxer S.G. Patterning and composition arrays of supported lipid bilayers by microcontact printing. Langmuir 2001, 17(11):3400-3405.
29. Lai E.S., Huang N.F., Cooke J.P., Fuller G.G. Aligned nanofibrillar collagen regulates endothelial organization and migration. Regen Med 2012, 7(5):649-661.
30. Peng K., Broz P., Jones J., Joubert L.M., Monack D. Elevated aim2-mediated pyroptosis triggered by hypercytotoxic francisella mutant strains is attributed to increased intracellular bacteriolysis. Cell Microbiol 2011, 13(10):1586-1600.
31. Huang N.F., Patel S., Thakar R.G., Wu J., Hsiao B.S., Chu B., et al. Myotube assembly on nanofibrous and micropatterned polymers. Nano Lett 2006, 6(3):537-542.
32. Lopez M.E., Klein A.D., Hong J., Dimbil U.J., Scott M.P. Neuronal and epithelial cell rescue resolves chronic systemic inflammation in the lipid storage disorder Niemann-Pick C. Hum Mol Genet 2012, 21(13):2946-2960.
33. Huang N.F., Fleissner F., Sun J., Cooke J.P. Role of nitric oxide signaling in endothelial differentiation of embryonic stem cells. Stem Cells Dev 2010, 19(10):1617-1626.
34. Tusher V.G., Tibshirani R., Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 2001, 98(9):5116-5121.
35. Subramanian A., Tamayo P., Mootha V.K., Mukherjee S., Ebert B.L., Gillette M.A., et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 2005, 102(43):15545-15550.
36. Pamukcu B., Lip G.Y., Devitt A., Griffiths H., Shantsila E. The role of monocytes in atherosclerotic coronary artery disease. Ann Med 2010, 42(6):394-403.
37. Tedgui A., Mallat Z. Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rev 2006, 86(2):515-581.
38. Ke L., Meijering R.A.M., Hoogstra-Berends F., Mackovicova K., Vos M.J., Van Gelder I.C., et al. Hspb1, HspB6, HspB7 and HspB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytes. PLoS One 2011, 6(6):e20395.
39. Lui W.-O., Pourmand N., Patterson B.K., Fire A. Patterns of known and novel small RNAs in human cervical cancer. Cancer Res 2007, 67(13):6031-6043.
40. Bostjancic E., Zidar N., Glavac D. MicroRNA microarray expression profiling in human myocardial infarction. Dis Markers 2009, 27(6):255-268.
41. Jones J.A., Stroud R.E., O'Quinn E.C., Black L.E., Barth J.L., Elefteriades J.A., et al. Selective microRNA suppression in human thoracic aneurysms/clinical perspective. Circ Cardiovasc Genet 2011, 4(6):605-613.
42. Laufen T., Mayer M.P., Beisel C., Klostermeier D., Mogk A., Reinstein J., et al. Mechanism of regulation of Hsp70 chaperones by DnaJ cochaperones. Proc Natl Acad Sci U S A 1999, 96(10):5452-5457.
43. Kurisu J., Honma A., Miyajima H., Kondo S., Okumura M., Imaizumi K. MDG1/ERdj4, an ER-resident DnaJ family member, suppresses cell death induced by ER stress. Genes Cells 2003, 8(2):189-202.
44. Inoue H., Taba Y., Miwa Y., Yokota C., Miyagi M., Sasaguri T. Transcriptional and posttranscriptional regulation of cyclooxygenase-2 expression by fluid shear stress in vascular endothelial cells. Arterioscler Thromb Vasc Biol 2002, 22(9):1415-1420.
45. Topper J.N., Cai J., Falb D., Gimbrone M.A. Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci U S A 1996, 93(19):10417-10422.
46. Anselme K., Davidson P., Popa A.M., Giazzon M., Liley M., Ploux L. The interaction of cells and bacteria with surfaces structured at the nanometre scale. Acta Biomater 2010, 6(10):3824-3846.
47. Malek A.M., Izumo S. Mechanism of endothelial cell shape change and cytoskeletal remodeling in response to fluid shear stress. J Cell Sci 1996, 109(4):713-726.
48. Vartanian K.B., Kirkpatrick S.J., Hanson S.R., Hinds M.T. Endothelial cell cytoskeletal alignment independent of fluid shear stress on micropatterned surfaces. Biochem Biophys Res Commun 2008, 371(4):787-792.
49. Boudreau N.J., Jones P.L. Extracellular matrix and integrin signalling: the shape of things to come. Biochem J 1999, 339(Pt 3):481-488.
50. Vogel V. Mechanotransduction involving multimodular proteins: converting force into biochemical signals. Annu Rev Biophys Biomol Struct 2006, 35:459-488.
51. Chien S. Effects of disturbed flow on endothelial cells. Ann Biomed Eng 2008, 36(4):554-562.
52. Chiu J.-J., Usami S., Chien S. Vascular endothelial responses to altered shear stress: pathologic implications for atherosclerosis. Ann Med 2009, 41(1):19-28.
53. Davies P.F., Civelek M., Fang Y., Guerraty M.A., Passerini A.G. Endothelial heterogeneity associated with regional athero-susceptibility and adaptation to disturbed blood flow in vivo. Semin Thromb Hemost 2010, 36(3):265-275.