-
1
-
-
39749142228
-
The search for new cardiovascular biomarkers
-
Gerszten R E., Wang T J. The search for new cardiovascular biomarkers. Nature 2008 451 (7181) 949-952
-
(2008)
Nature
, vol.451
, Issue.7181
, pp. 949-952
-
-
Gerszten, R.E.1
Wang, T.J.2
-
2
-
-
0034019601
-
Lessons from sudden coronary death: A comprehensive morphological classification scheme for atherosclerotic lesions
-
Virmani R, Kolodgie F D., Burke A P., Farb A, Schwartz S M. Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2000 20 (5) 1262-1275
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, Issue.5
, pp. 1262-1275
-
-
Virmani, R.1
Kolodgie, F.D.2
Burke, A.P.3
Farb, A.4
Schwartz, S.M.5
-
3
-
-
0036853543
-
Atherogenesis in perspective: Hypercholesterolemia and inflammation as partners in crime
-
Steinberg D. Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime. Nat Med 2002 8 (11) 1211-1217
-
(2002)
Nat Med
, vol.8
, Issue.11
, pp. 1211-1217
-
-
Steinberg, D.1
-
4
-
-
33745571976
-
The immune response in atherosclerosis: A double-edged sword
-
Hansson G K., Libby P. The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol 2006 6 (7) 508-519
-
(2006)
Nat Rev Immunol
, vol.6
, Issue.7
, pp. 508-519
-
-
Hansson, G.K.1
Libby, P.2
-
5
-
-
4944266004
-
Genetic basis of atherosclerosis: Part II: Clinical implications
-
Lusis A J., Fogelman A M., Fonarow G C. Genetic basis of atherosclerosis: part II: clinical implications. Circulation 2004 110 (14) 2066-2071
-
(2004)
Circulation
, vol.110
, Issue.14
, pp. 2066-2071
-
-
Lusis, A.J.1
Fogelman, A.M.2
Fonarow, G.C.3
-
6
-
-
0029072762
-
Flow-mediated endothelial mechanotransduction
-
Davies P F. Flow-mediated endothelial mechanotransduction. Physiol Rev 1995 75 (3) 519-560
-
(1995)
Physiol Rev
, vol.75
, Issue.3
, pp. 519-560
-
-
Davies, P.F.1
-
7
-
-
58049213790
-
Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology
-
Davies P F. Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology. Nat Clin Pract Cardiovasc Med 2009 6 (1) 16-26
-
(2009)
Nat Clin Pract Cardiovasc Med
, vol.6
, Issue.1
, pp. 16-26
-
-
Davies, P.F.1
-
8
-
-
10744233033
-
Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta
-
Passerini A G., Polacek D C., Shi C et al. Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta. Proc Natl Acad Sci U S A 2004 101 (8) 2482-2487
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.8
, pp. 2482-2487
-
-
Passerini, A.G.1
Polacek, D.C.2
Shi, C.3
-
9
-
-
0034255365
-
The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation
-
Hajra L, Evans A I., Chen M, Hyduk S J., Collins T, Cybulsky M I. The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation. Proc Natl Acad Sci U S A 2000 97 (16) 9052-9057
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.16
, pp. 9052-9057
-
-
Hajra, L.1
Evans, A.I.2
Chen, M.3
Hyduk, S.J.4
Collins, T.5
Cybulsky, M.I.6
-
10
-
-
0000616560
-
Special communication: The critical role of mechanical forces in blood vessel development, physiology and pathology
-
Gimbrone M A. Jr, Anderson K R., Topper J N. et al. Special communication: the critical role of mechanical forces in blood vessel development, physiology and pathology. J Vasc Surg 1999 29 (6) 1104-1151
-
(1999)
J Vasc Surg
, vol.29
, Issue.6
, pp. 1104-1151
-
-
Gimbrone, Jr.M.A.1
Anderson, K.R.2
Topper, J.N.3
-
11
-
-
0033198129
-
A spatial approach to transcriptional profiling: Mechanotransduction and the focal origin of atherosclerosis
-
Davies P F., Polacek D C., Handen J S., Helmke B P., DePaola N. A spatial approach to transcriptional profiling: mechanotransduction and the focal origin of atherosclerosis. Trends Biotechnol 1999 17 (9) 347-351
-
(1999)
Trends Biotechnol
, vol.17
, Issue.9
, pp. 347-351
-
-
Davies, P.F.1
Polacek, D.C.2
Handen, J.S.3
Helmke, B.P.4
Depaola, N.5
-
12
-
-
12644260471
-
Vascular MADs: Two novel MAD-related genes selectively inducible by flow in human vascular endothelium
-
Topper J N., Cai J, Qiu Y et al. Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium. Proc Natl Acad Sci U S A 1997 94 (17) 9314-9319
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, Issue.17
, pp. 9314-9319
-
-
Topper, J.N.1
Cai, J.2
Qiu, Y.3
-
13
-
-
0027931392
-
Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells
-
Nagel T, Resnick N, Atkinson W J., Dewey C F. Jr, Gimbrone M A. Jr. Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells. J Clin Invest 1994 94 (2) 885-891
-
(1994)
J Clin Invest
, vol.94
, Issue.2
, pp. 885-891
-
-
Nagel, T.1
Resnick, N.2
Atkinson, W.J.3
Dewey, Jr.C.F.4
Gimbrone, Jr.M.A.5
-
14
-
-
0347486631
-
DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress
-
Chen B P., Li Y S., Zhao Y et al. DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress. Physiol Genomics 2001 7 (1) 55-63
-
(2001)
Physiol Genomics
, vol.7
, Issue.1
, pp. 55-63
-
-
Chen, B.P.1
Li, Y.S.2
Zhao, Y.3
-
15
-
-
0033026830
-
Spatial regulation of gap junction connexin 43 in endothelial cells exposed to controlled disturbed flows in vitro
-
DePaola N, Davies P F., Pritchard W F. et al. Spatial regulation of gap junction connexin 43 in endothelial cells exposed to controlled disturbed flows in vitro. Proc Natl Acad Sci U S A 1999 96 3154-3159
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3154-3159
-
-
Depaola, N.1
Davies, P.F.2
Pritchard, W.F.3
-
16
-
-
0035836653
-
Biomechanical activation of vascular endothelium as a determinant of its functional phenotype
-
Garcia-Cardeña G, Comander J, Anderson K R., Blackman B R., Gimbrone M A. Jr. Biomechanical activation of vascular endothelium as a determinant of its functional phenotype. Proc Natl Acad Sci U S A 2001 98 (8) 4478-4485
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.8
, pp. 4478-4485
-
-
Garcia-Cardeña, G.1
Comander, J.2
Anderson, K.R.3
Blackman, B.R.4
Gimbrone, Jr.M.A.5
-
17
-
-
0037180745
-
Gene expression profile of human endothelial cells exposed to sustained fluid shear stress
-
Wasserman S M., Mehraban F, Komuves L G. et al. Gene expression profile of human endothelial cells exposed to sustained fluid shear stress. Physiol Genomics 2002 12 (1) 13-23
-
(2002)
Physiol Genomics
, vol.12
, Issue.1
, pp. 13-23
-
-
Wasserman, S.M.1
Mehraban, F.2
Komuves, L.G.3
-
18
-
-
0036721376
-
Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2)
-
Dekker R J., van Soest S, Fontijn R D. et al. Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2). Blood 2002 100 (5) 1689-1698
-
(2002)
Blood
, vol.100
, Issue.5
, pp. 1689-1698
-
-
Dekker, R.J.1
Van Soest, S.2
Fontijn, R.D.3
-
19
-
-
24744449131
-
Endothelial protein kinase C isoform identity and differential activity of PKCzeta in an athero-susceptible region of porcine aorta
-
Magid R, Davies P F. Endothelial protein kinase C isoform identity and differential activity of PKCzeta in an athero-susceptible region of porcine aorta. Circ Res 2005 97 (5) 443-449
-
(2005)
Circ Res
, vol.97
, Issue.5
, pp. 443-449
-
-
Magid, R.1
Davies, P.F.2
-
20
-
-
0037417983
-
Beneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress
-
de Nigris F, Lerman L O., Ignarro S W. et al. Beneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress. Proc Natl Acad Sci U S A 2003 100 (3) 1420-1425
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.3
, pp. 1420-1425
-
-
De Nigris, F.1
Lerman, L.O.2
Ignarro, S.W.3
-
21
-
-
17644380642
-
Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves
-
Simmons C A., Grant G R., Manduchi E, Davies P F. Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves. Circ Res 2005 96 (7) 792-799
-
(2005)
Circ Res
, vol.96
, Issue.7
, pp. 792-799
-
-
Simmons, C.A.1
Grant, G.R.2
Manduchi, E.3
Davies, P.F.4
-
22
-
-
21144439016
-
Regional determinants of arterial endothelial phenotype dominate the impact of gender or short-term exposure to a high-fat diet
-
Passerini A G., Shi C, Francesco N M. et al. Regional determinants of arterial endothelial phenotype dominate the impact of gender or short-term exposure to a high-fat diet. Biochem Biophys Res Commun 2005 332 (1) 142-148
-
(2005)
Biochem Biophys Res Commun
, vol.332
, Issue.1
, pp. 142-148
-
-
Passerini, A.G.1
Shi, C.2
Francesco, N.M.3
-
23
-
-
84928851765
-
-
Hemodynamics in the determination of the endothelial phenotype and flow mechanotransduction In: Aird WC Cambridge, United Kingdom Cambridge University Press
-
Davies P F. Hemodynamics in the determination of the endothelial phenotype and flow mechanotransduction In: Aird WC Endothelial Biomedicine; A Comprehensive Treatise. Cambridge, United Kingdom Cambridge University Press 2007 230-245
-
(2007)
Endothelial Biomedicine; A Comprehensive Treatise
, pp. 230-245
-
-
Davies, P.F.1
-
24
-
-
70149098183
-
Chronic endoplasmic reticulum stress activates unfolded protein response in arterial endothelium in regions of susceptibility to atherosclerosis
-
Civelek M, Manduchi E, Riley R J., Stoeckert C J. Jr, Davies P F. Chronic endoplasmic reticulum stress activates unfolded protein response in arterial endothelium in regions of susceptibility to atherosclerosis. Circ Res 2009 105 (5) 453-461
-
(2009)
Circ Res
, vol.105
, Issue.5
, pp. 453-461
-
-
Civelek, M.1
Manduchi, E.2
Riley, R.J.3
Stoeckert, Jr.C.J.4
Davies, P.F.5
-
25
-
-
75149144852
-
Hypercholesterolemia induces side-specific phenotypic changes and peroxisome proliferator-activated pathway activation in swine aortic valve endothelium
-
Guerraty M A., Grant G R., Karanian J W., Chiesa O A., Pritchard W P., Davies P F. Hypercholesterolemia induces side-specific phenotypic changes and peroxisome proliferator-activated pathway activation in swine aortic valve endothelium. Arterioscler Thromb Vasc Biol 2010 30 (2) 225-231
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, Issue.2
, pp. 225-231
-
-
Guerraty, M.A.1
Grant, G.R.2
Karanian, J.W.3
Chiesa, O.A.4
Pritchard, W.P.5
Davies, P.F.6
-
26
-
-
73549089464
-
Pre-lesional arterial endothelial phemotypes in hypercholesterolemia: Universal ABCA1 upregulation contrasts with region-specific gene expression in vivo
-
Civelek M, Grant G R., Irolla C R. et al. Pre-lesional arterial endothelial phemotypes in hypercholesterolemia: universal ABCA1 upregulation contrasts with region-specific gene expression in vivo. Am J Physiol Heart Circ Physiol 2010 298 (1) H163-170
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
, Issue.1
-
-
Civelek, M.1
Grant, G.R.2
Irolla, C.R.3
-
27
-
-
0033597952
-
Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation
-
Iiyama K, Hajra L, Iiyama M et al. Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation. Circ Res 1999 85 (2) 199-207
-
(1999)
Circ Res
, vol.85
, Issue.2
, pp. 199-207
-
-
Iiyama, K.1
Hajra, L.2
Iiyama, M.3
-
28
-
-
52449111898
-
GRP78 upregulation by atheroprone shear stress via p38-, alpha2beta1-dependent mechanism in endothelial cells
-
Feaver R E., Hastings N E., Pryor A, Blackman B R. GRP78 upregulation by atheroprone shear stress via p38-, alpha2beta1-dependent mechanism in endothelial cells. Arterioscler Thromb Vasc Biol 2008 28 (8) 1534-1541
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, Issue.8
, pp. 1534-1541
-
-
Feaver, R.E.1
Hastings, N.E.2
Pryor, A.3
Blackman, B.R.4
-
29
-
-
66249117652
-
Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow
-
Zeng L, Zampetaki A, Margariti A et al. Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow. Proc Natl Acad Sci U S A 2009 106 (20) 8326-8331
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.20
, pp. 8326-8331
-
-
Zeng, L.1
Zampetaki, A.2
Margariti, A.3
-
30
-
-
0033562966
-
Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
-
Kaufman R J. Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev 1999 13 (10) 1211-1233
-
(1999)
Genes Dev
, vol.13
, Issue.10
, pp. 1211-1233
-
-
Kaufman, R.J.1
-
31
-
-
22244446505
-
The mammalian unfolded protein response
-
Schröder M, Kaufman R J. The mammalian unfolded protein response. Annu Rev Biochem 2005 74 739-789
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 739-789
-
-
Schröder, M.1
Kaufman, R.J.2
-
32
-
-
35348827324
-
That which does not kill me makes me stronger: Adapting to chronic ER stress
-
Rutkowski D T., Kaufman R J. That which does not kill me makes me stronger: adapting to chronic ER stress. Trends Biochem Sci 2007 32 (10) 469-476
-
(2007)
Trends Biochem Sci
, vol.32
, Issue.10
, pp. 469-476
-
-
Rutkowski, D.T.1
Kaufman, R.J.2
-
33
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
Cullinan S B., Zhang D, Hannink M, Arvisais E, Kaufman R J., Diehl J A. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol Cell Biol 2003 23 (20) 7198-7209
-
(2003)
Mol Cell Biol
, vol.23
, Issue.20
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
34
-
-
0017279002
-
Clustering of replicating cells in aortic endothelium
-
Schwartz S M., Benditt E P. Clustering of replicating cells in aortic endothelium. Proc Natl Acad Sci U S A 1976 73 (2) 651-653
-
(1976)
Proc Natl Acad Sci U S A
, vol.73
, Issue.2
, pp. 651-653
-
-
Schwartz, S.M.1
Benditt, E.P.2
-
35
-
-
0028824403
-
Ultrastructural studies on macromolecular permeability in relation to endothelial cell turnover
-
Chen Y L., Jan K M., Lin H S., Chien S. Ultrastructural studies on macromolecular permeability in relation to endothelial cell turnover. Atherosclerosis 1995 118 (1) 89-104
-
(1995)
Atherosclerosis
, vol.118
, Issue.1
, pp. 89-104
-
-
Chen, Y.L.1
Jan, K.M.2
Lin, H.S.3
Chien, S.4
-
36
-
-
35848957485
-
Endoplasmic reticulum stress and oxidative stress: A vicious cycle or a double-edged sword?
-
Malhotra J D., Kaufman R J. Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword? Antioxid Redox Signal 2007 9 (12) 2277-2293
-
(2007)
Antioxid Redox Signal
, vol.9
, Issue.12
, pp. 2277-2293
-
-
Malhotra, J.D.1
Kaufman, R.J.2
-
37
-
-
0842266604
-
Oxidative protein folding in eukaryotes: Mechanisms and consequences
-
Tu B P., Weissman J S. Oxidative protein folding in eukaryotes: mechanisms and consequences. J Cell Biol 2004 164 (3) 341-346
-
(2004)
J Cell Biol
, vol.164
, Issue.3
, pp. 341-346
-
-
Tu, B.P.1
Weissman, J.S.2
-
38
-
-
47949099916
-
From endoplasmic-reticulum stress to the inflammatory response
-
Zhang K, Kaufman R J. From endoplasmic-reticulum stress to the inflammatory response. Nature 2008 454 (7203) 455-462
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 455-462
-
-
Zhang, K.1
Kaufman, R.J.2
-
39
-
-
33750221963
-
The unfolded protein response is an important regulator of inflammatory genes in endothelial cells
-
Gargalovic P S., Gharavi N M., Clark M J. et al. The unfolded protein response is an important regulator of inflammatory genes in endothelial cells. Arterioscler Thromb Vasc Biol 2006 26 (11) 2490-2496
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, Issue.11
, pp. 2490-2496
-
-
Gargalovic, P.S.1
Gharavi, N.M.2
Clark, M.J.3
-
40
-
-
0028291843
-
Stimulation of transcription factors NF kappa B and AP1 in endothelial cells subjected to shear stress
-
Lan Q, Mercurius K O., Davies P F. Stimulation of transcription factors NF kappa B and AP1 in endothelial cells subjected to shear stress. Biochem Biophys Res Commun 1994 201 (2) 950-956
-
(1994)
Biochem Biophys Res Commun
, vol.201
, Issue.2
, pp. 950-956
-
-
Lan, Q.1
Mercurius, K.O.2
Davies, P.F.3
-
41
-
-
0028982830
-
Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress
-
Khachigian L M., Resnick N, Gimbrone M A. Jr, Collins T. Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress. J Clin Invest 1995 96 (2) 1169-1175
-
(1995)
J Clin Invest
, vol.96
, Issue.2
, pp. 1169-1175
-
-
Khachigian, L.M.1
Resnick, N.2
Gimbrone, Jr.M.A.3
Collins, T.4
-
42
-
-
0034746311
-
NF-kappaB: Pivotal mediator or innocent bystander in atherogenesis?
-
Collins T, Cybulsky M I. NF-kappaB: pivotal mediator or innocent bystander in atherogenesis? J Clin Invest 2001 107 (3) 255-264
-
(2001)
J Clin Invest
, vol.107
, Issue.3
, pp. 255-264
-
-
Collins, T.1
Cybulsky, M.I.2
-
43
-
-
34547684022
-
Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis
-
Volger O L., Fledderus J O., Kisters N et al. Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis. Am J Pathol 2007 171 (1) 326-337
-
(2007)
Am J Pathol
, vol.171
, Issue.1
, pp. 326-337
-
-
Volger, O.L.1
Fledderus, J.O.2
Kisters, N.3
-
44
-
-
33751069967
-
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
-
Rutkowski D T., Arnold S M., Miller C N. et al. Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. PLoS Biol 2006 4 (11) e374
-
(2006)
PLoS Biol
, vol.4
, Issue.11
-
-
Rutkowski, D.T.1
Arnold, S.M.2
Miller, C.N.3
-
45
-
-
0034723235
-
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
-
Urano F, Wang X, Bertolotti A et al. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 2000 287 (5453) 664-666
-
(2000)
Science
, vol.287
, Issue.5453
, pp. 664-666
-
-
Urano, F.1
Wang, X.2
Bertolotti, A.3
-
46
-
-
77953526401
-
-
Paper presented at: Annual Scientific Meeting of the Biomedical Engineering Society Pittsburgh, PA
-
Fang Y, Civelek M, Shi C, Manduchi E, Davies P F. MicroRNA 10a suppresses NF-kappa-B pathway that mediates athero-prone endothelial phenotype. Paper presented at: Annual Scientific Meeting of the Biomedical Engineering Society October 8, 2009 Pittsburgh, PA
-
(2009)
MicroRNA 10a Suppresses NF-kappa-B Pathway That Mediates Athero-prone Endothelial Phenotype
-
-
Fang, Y.1
Civelek, M.2
Shi, C.3
Manduchi, E.4
Davies, P.F.5
|