Functional expression of a proton-coupled organic cation (H+/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood-brain barrier model

Fluids and Barriers of the CNS

Volumn 10, Issue 1, 2013, Pages

  Shimomura, Keita ^a   Okura, Takashi ^a   Kato, Sayaka ^a   Couraud, Pierre Olivier ^b,c,d   Schermann, Jean Michel ^c,e   Terasaki, Tetsuya ^f   Deguchi, Yoshiharu ^a  

^a TEIKYO UNIVERSITY   (Japan)

^b INSTITUT COCHIN   (France)

^c CNRS   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e INSERM   (France)

^f TOHOKU UNIVERSITY   (Japan)

Author keywords

Active transport; Diphenhydramine; HCMEC D3 cells; Human BBB model cell; Human blood brain barrier; Organic cation transporter; Oxycodone; Proton coupled organic cation antiporter; Pyrilamine; Real time PCR; Transport function

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; AMANTADINE; ANTIPORTER; MESSENGER RNA; OXYCODONE; PROTON COUPLED ORGANIC CATION ANTIPORTER; QUINIDINE; SODIUM; TETRYLAMMONIUM; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN PERFUSION; CELL TRANSPORT; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MEMBRANE POTENTIAL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION;

EID: 84873456457     PISSN: None     EISSN: 20458118     Source Type: Journal    
DOI: 10.1186/2045-8118-10-8     Document Type: Article

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