The involvement of a Na +- and Cl --dependent transporter in the brain uptake of amantadine and rimantadine

Molecular Pharmaceutics

Volumn 9, Issue 4, 2012, Pages 883-893

  Kooijmans, Sander A A ^a   Senyschyn, Danielle ^a   Mezhiselvam, Muguntha M ^a   Morizzi, Julia ^a   Charman, Susan A ^a   Weksler, Babette ^b   Romero, Ignacio Andres ^c   Couraud, Pierre Olivier ^d,e   Nicolazzo, Joseph A ^a  

^a MONASH UNIVERSITY   (Australia)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c OPEN UNIVERSITY   (United Kingdom)

^d INSTITUT COCHIN   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

amantadine; amino acid transporter B 0,+; blood brain barrier; rimantadine

Indexed keywords

AMANTADINE; AMINO ACID TRANSPORTER; CATION; CHLORIDE ION; CHOLINE; CIMETIDINE; GLYCINE; QUININE; RIMANTADINE; SODIUM ION; TETRYLAMMONIUM;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; DRUG BINDING; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; DRUG UPTAKE; ENDOTHELIUM CELL; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IN VIVO STUDY; ION TRANSPORT; MALE; MEMBRANE DEPOLARIZATION; MICHAELIS MENTEN KINETICS; MOUSE; NONHUMAN; PLASMA PROTEIN BINDING; PRIORITY JOURNAL;

AMANTADINE; AMINO ACID TRANSPORT SYSTEMS; ANIMALS; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN; HUMANS; MICE; RIMANTADINE;

EID: 84859332881     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp2004127     Document Type: Article

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