메뉴 건너뛰기




Volumn 5, Issue , 2012, Pages 535-540

Effects of pitavastatin on plasminogen activator inhibitor-1 in hyperlipidemic patients

Author keywords

Adiponectin; Atherothrombosis; Hyperlipidemia; PAI 1; Pitavastatin

Indexed keywords

ADIPONECTIN; CD40 LIGAND; PADGEM PROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PRAVASTATIN; SOLUBLE CD40 LIGAND; SOLUBLE P SELECTIN; UNCLASSIFIED DRUG;

EID: 84873447434     PISSN: None     EISSN: 11787074     Source Type: Journal    
DOI: 10.2147/IJGM.S31346     Document Type: Article
Times cited : (8)

References (45)
  • 1
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ. Atherosclerosis. Nature. 2000;407:233-241.
    • (2000) Nature. , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 2
    • 0025325318 scopus 로고
    • Leukocyte and platelet function and eicosanoid production in subjects with hypercholesterolemia
    • Croft KD, Beilin LJ, Vandongen R, Rouse I, Masarei J. Leukocyte and platelet function and eicosanoid production in subjects with hypercholesterolemia. Atherosclerosis. 1990;83:101-109.
    • (1990) Atherosclerosis. , vol.83 , pp. 101-109
    • Croft, K.D.1    Beilin, L.J.2    Vandongen, R.3    Rouse, I.4    Masarei, J.5
  • 3
    • 0025769996 scopus 로고
    • Single risk factor intervention may be inadequate to inhibit atherosclerosis progression when hypertension and hypercholesterolemia co-exist
    • Chobanian AV. Single risk factor intervention may be inadequate to inhibit atherosclerosis progression when hypertension and hypercholesterolemia co-exist. Hypertension. 1991;18:130-131.
    • (1991) Hypertension. , vol.18 , pp. 130-131
    • Chobanian, A.V.1
  • 4
    • 0001208808 scopus 로고
    • Malondialdehyde alteration of low density lipoproteins leads to chelesterylester accumulation in macrophages
    • Fogelman A, Schechter I, Seager J, et al. Malondialdehyde alteration of low density lipoproteins leads to chelesterylester accumulation in macrophages. Proc Natl Acad Sci U S A. 1980;77:2214-2218.
    • (1980) Proc Natl Acad Sci U S A. , vol.77 , pp. 2214-2218
    • Fogelman, A.1    Schechter, I.2    Seager, J.3
  • 5
    • 0027979451 scopus 로고
    • Recent observations on the role of hemostatic determinants in the development of the atherosclerotic plaque
    • Rabbani LE, Loscalzo J. Recent observations on the role of hemostatic determinants in the development of the atherosclerotic plaque. Atherosclerosis. 1994;105:1-7.
    • (1994) Atherosclerosis. , vol.105 , pp. 1-7
    • Rabbani, L.E.1    Loscalzo, J.2
  • 6
    • 0242407768 scopus 로고    scopus 로고
    • Intramural plasminogen activator inhibitor type-1 and coronary atherosclerosis
    • Sobel BE, Taatjes DJ, Schneider DJ. Intramural plasminogen activator inhibitor type-1 and coronary atherosclerosis. Artherioscler Thromb Vasc Biol. 2003;23:1979-1989.
    • (2003) Artherioscler Thromb Vasc Biol. , vol.23 , pp. 1979-1989
    • Sobel, B.E.1    Taatjes, D.J.2    Schneider, D.J.3
  • 7
    • 67650065293 scopus 로고    scopus 로고
    • Involvement of NADPH oxidase in oxidized LDL-induced upregulation of heat shock factor-1 and plasminogen activator inhibitor-1in vascular endothelial cells
    • Zhao R, Ma X, Xie X, Shen GX. Involvement of NADPH oxidase in oxidized LDL-induced upregulation of heat shock factor-1 and plasminogen activator inhibitor-1in vascular endothelial cells. Am J Physiol Endocrino Metab. 2009;297:E104-E111.
    • (2009) Am J Physiol Endocrino Metab. , vol.297
    • Zhao, R.1    Ma, X.2    Xie, X.3    Shen, G.X.4
  • 8
    • 78651256770 scopus 로고    scopus 로고
    • Oxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression through reactive oxygen species generation and ERK1/2 activation in 3T3-L1 adipocytes
    • Kuniyasu A, Tokunaga M, Yamamoto T, et al. Oxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression through reactive oxygen species generation and ERK1/2 activation in 3T3-L1 adipocytes. Biochim Biophys Acta. 2011;1811:153-162.
    • (2011) Biochim Biophys Acta. , vol.1811 , pp. 153-162
    • Kuniyasu, A.1    Tokunaga, M.2    Yamamoto, T.3
  • 9
    • 0031987937 scopus 로고    scopus 로고
    • Vascular cell-derived fibrinolytic regulators and atherothrombotic vascular disorders
    • Shen GX. Vascular cell-derived fibrinolytic regulators and atherothrombotic vascular disorders. Int J Mol Med. 1998;1:399-408.
    • (1998) Int J Mol Med. , vol.1 , pp. 399-408
    • Shen, G.X.1
  • 10
    • 0034641647 scopus 로고    scopus 로고
    • Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappa B signaling through a cAMP-dependent pathway
    • Ouchi N, Kihara S, Arita Y, et al. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappa B signaling through a cAMP-dependent pathway. Circulation. 2000;102:1296-1301.
    • (2000) Circulation. , vol.102 , pp. 1296-1301
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3
  • 11
    • 0033515761 scopus 로고    scopus 로고
    • Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
    • Arita Y, Kihara S, Ouchi N, et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun. 1999;257:79-83.
    • (1999) Biochem Biophys Res Commun. , vol.257 , pp. 79-83
    • Arita, Y.1    Kihara, S.2    Ouchi, N.3
  • 12
    • 0034096988 scopus 로고    scopus 로고
    • Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetes patients
    • Hotta K, Funahashi T, Arita Y, et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetes patients. Artherioscler Thromb Vasc Biol. 2000;20:1595-1599.
    • (2000) Artherioscler Thromb Vasc Biol. , vol.20 , pp. 1595-1599
    • Hotta, K.1    Funahashi, T.2    Arita, Y.3
  • 13
    • 0034999667 scopus 로고    scopus 로고
    • Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
    • Weyer C, Funahashi T, Tanaka S, et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab. 2001;86:1930-1935.
    • (2001) J Clin Endocrinol Metab. , vol.86 , pp. 1930-1935
    • Weyer, C.1    Funahashi, T.2    Tanaka, S.3
  • 14
    • 0242581695 scopus 로고    scopus 로고
    • Adiponectin stimulates production of nitric oxide in vascular endothelial cells
    • Chen H, Montagnani M, Funahashi T, Shimomura I, Quon MJ. Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J Biol Chem. 2003;278:45021-45026.
    • (2003) J Biol Chem. , vol.278 , pp. 45021-45026
    • Chen, H.1    Montagnani, M.2    Funahashi, T.3    Shimomura, I.4    Quon, M.J.5
  • 15
    • 0345117404 scopus 로고    scopus 로고
    • Globular adiponectin upregulates nitric oxide production in vascular endothelial cells
    • Hattori Y, Suzuki M, Hattori S, Kasai K. Globular adiponectin upregulates nitric oxide production in vascular endothelial cells. Diabetologia. 2003;46:1543-1549.
    • (2003) Diabetologia. , vol.46 , pp. 1543-1549
    • Hattori, Y.1    Suzuki, M.2    Hattori, S.3    Kasai, K.4
  • 16
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simbvastatin Survival Study Group
    • Scandinavian Simbvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 1994;344:1383-1389.
    • (1994) Lancet. , vol.344 , pp. 1383-1389
  • 17
    • 0032554676 scopus 로고    scopus 로고
    • Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS)
    • West of Scotland Coronary Prevention Group
    • West of Scotland Coronary Prevention Group. Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS). Circulation. 1998;97:1440-1445.
    • (1998) Circulation. , vol.97 , pp. 1440-1445
  • 18
    • 77956226709 scopus 로고    scopus 로고
    • Beneficial direct adipotropic actions of pitavastatin in vitro and their manifestations in obese mice
    • Ishihara Y, Ohmori K, Mizukawa M, et al. Beneficial direct adipotropic actions of pitavastatin in vitro and their manifestations in obese mice. Atherosclerosis. 2010;212:131-138.
    • (2010) Atherosclerosis. , vol.212 , pp. 131-138
    • Ishihara, Y.1    Ohmori, K.2    Mizukawa, M.3
  • 19
    • 0036015997 scopus 로고    scopus 로고
    • Long-term treatment with pitavastatin (NK-104), a new HMG-CoA reductase inhibitor, in patients with heterozygous familial hypercholesterolemia
    • Noji Y, Higashikata T, Inazu A, et al. Long-term treatment with pitavastatin (NK-104), a new HMG-CoA reductase inhibitor, in patients with heterozygous familial hypercholesterolemia. Atherosclerosis. 2002;163:157-164.
    • (2002) Atherosclerosis. , vol.163 , pp. 157-164
    • Noji, Y.1    Higashikata, T.2    Inazu, A.3
  • 20
    • 0036231636 scopus 로고    scopus 로고
    • Clinical efficacy of pitavastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in patients with hyperlipidemia: Dose-finding study using the double-bind, three-group parallel comparison
    • Saito Y, Yamada N, Teramoto T, et al. Clinical efficacy of pitavastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in patients with hyperlipidemia: dose-finding study using the double-bind, three-group parallel comparison. Arzeimittelforschung. 2002;52:251-255.
    • (2002) Arzeimittelforschung. , vol.52 , pp. 251-255
    • Saito, Y.1    Yamada, N.2    Teramoto, T.3
  • 21
    • 1242336795 scopus 로고    scopus 로고
    • Pitavastatin downregulates expression of the macrophage type B scavenger receptor, CD36
    • Han J, Zhou X, Yokoyama T, et al. Pitavastatin downregulates expression of the macrophage type B scavenger receptor, CD36. Circulation. 2004;109:790-796.
    • (2004) Circulation. , vol.109 , pp. 790-796
    • Han, J.1    Zhou, X.2    Yokoyama, T.3
  • 22
    • 13244292570 scopus 로고    scopus 로고
    • Pitavastatin inhibits remnant lipoprotein-induced macrophage foam cell formation through apoB48 receptor-dependent mechanism
    • Kawakami A, Tani M, Chiba T, et al. Pitavastatin inhibits remnant lipoprotein-induced macrophage foam cell formation through apoB48 receptor-dependent mechanism. Artherioscler Thromb Vasc Biol. 2005;25:424-429.
    • (2005) Artherioscler Thromb Vasc Biol. , vol.25 , pp. 424-429
    • Kawakami, A.1    Tani, M.2    Chiba, T.3
  • 23
    • 14144256390 scopus 로고    scopus 로고
    • Pitavastatin at low dose activates endothelial nitric oxide synthase through PI3K-AKT pathway in endothelial cells
    • Wang J, Tokoro T, Matsui K, Higa S, Kitajima J. Pitavastatin at low dose activates endothelial nitric oxide synthase through PI3K-AKT pathway in endothelial cells. Life Scien. 2005;76:2257-2268.
    • (2005) Life Scien. , vol.76 , pp. 2257-2268
    • Wang, J.1    Tokoro, T.2    Matsui, K.3    Higa, S.4    Kitajima, J.5
  • 24
    • 0003175257 scopus 로고    scopus 로고
    • Investigating Committee of Guideline for Diagnosis and Treatment of Hyperlipidemia, Japan Atherosclerosis Society (JAS): Guideline for Diagnosis and Treatment of Hyperlipidemias in Adults
    • The Expert Committee on the Guideline for Diagnosis and Treatment of Hyperlipidemia
    • The Expert Committee on the Guideline for Diagnosis and Treatment of Hyperlipidemia. Investigating Committee of Guideline for Diagnosis and Treatment of Hyperlipidemia, Japan Atherosclerosis Society (JAS): Guideline for Diagnosis and Treatment of Hyperlipidemias in Adults. Doumyakukouka. 1997;25:1-34.
    • (1997) Doumyakukouka. , vol.25 , pp. 1-34
  • 25
    • 0012431804 scopus 로고    scopus 로고
    • Report of the expert commitee on the diagnosis and classification of diabetes mellitus
    • The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (ECDCDM)
    • The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (ECDCDM). Report of the expert commitee on the diagnosis and classification of diabetes mellitus. Diabetes Care. 2003; (26 Suppl 1):S5-S20.
    • (2003) Diabetes Care , Issue.26 SUPPL. 1
  • 26
    • 0035128766 scopus 로고    scopus 로고
    • Development and assessment of enzyme immunoassay for platelet-derived microparticles
    • Osumi K, Ozeki Y, Saito S, et al. Development and assessment of enzyme immunoassay for platelet-derived microparticles. Thromb Haemost. 2001;85:326-330.
    • (2001) Thromb Haemost. , vol.85 , pp. 326-330
    • Osumi, K.1    Ozeki, Y.2    Saito, S.3
  • 27
    • 0037340351 scopus 로고    scopus 로고
    • Enzyme immunoassay detection of platelet-derived microparticles and RANTES in acute coronary syndrome
    • Nomura S, Uehata S, Saito S, et al. Enzyme immunoassay detection of platelet-derived microparticles and RANTES in acute coronary syndrome. Thromb Haemost. 2003;89:506-512.
    • (2003) Thromb Haemost. , vol.89 , pp. 506-512
    • Nomura, S.1    Uehata, S.2    Saito, S.3
  • 28
    • 0025734531 scopus 로고
    • Increased plasma plasminogen activator inhibitor 1 levels: A possible link between insulin resistance and atherothrombosis
    • Juhan-Vague I, Alessi MC, Vague P. Increased plasma plasminogen activator inhibitor 1 levels: a possible link between insulin resistance and atherothrombosis. Diabetologia. 1991;34:457-462.
    • (1991) Diabetologia. , vol.34 , pp. 457-462
    • Juhan-Vague, I.1    Alessi, M.C.2    Vague, P.3
  • 29
    • 0030685740 scopus 로고    scopus 로고
    • Inhibitory role of plasminogen activator inhibitor-1in arterial healing and neointima formation: A gene targeting and gene transfer study in mice
    • Carmelier P, Moons L, Lijnen R, et al. Inhibitory role of plasminogen activator inhibitor-1in arterial healing and neointima formation: a gene targeting and gene transfer study in mice. Circulation. 1997;96:3180-3191.
    • (1997) Circulation. , vol.96 , pp. 3180-3191
    • Carmelier, P.1    Moons, L.2    Lijnen, R.3
  • 30
    • 30644477115 scopus 로고    scopus 로고
    • Effects of oxidized and glycated low-density lipoprotections on transcription and secretion of plasminogen activator inhibitor-1in vascular endothelial cells
    • Ma GM, Halayko AJ, Stelmack GL, et al. Effects of oxidized and glycated low-density lipoprotections on transcription and secretion of plasminogen activator inhibitor-1in vascular endothelial cells. Cardiovasc Pathol. 2006;15:3-10.
    • (2006) Cardiovasc Pathol. , vol.15 , pp. 3-10
    • Ma, G.M.1    Halayko, A.J.2    Stelmack, G.L.3
  • 31
    • 0033373547 scopus 로고    scopus 로고
    • Oxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression in vascular smooth muscle cells
    • Dichtl W, Stiko A, Eriksson P, et al. Oxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression in vascular smooth muscle cells. Artherioscler Thromb Vasc Biol. 1999;19:3025-3032.
    • (1999) Artherioscler Thromb Vasc Biol. , vol.19 , pp. 3025-3032
    • Dichtl, W.1    Stiko, A.2    Eriksson, P.3
  • 32
    • 0037195054 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 promotes formation of endothelial microparticles with procoagulant potential
    • Brodsky SV, Malinowski K, Golightly M, Jesty J, Goligorsly MS. Plasminogen activator inhibitor-1 promotes formation of endothelial microparticles with procoagulant potential. Circulation. 2002;106: 2372-2378.
    • (2002) Circulation. , vol.106 , pp. 2372-2378
    • Brodsky, S.V.1    Malinowski, K.2    Golightly, M.3    Jesty, J.4    Goligorsly, M.S.5
  • 33
    • 34250172420 scopus 로고    scopus 로고
    • Low serum adiponectin is associated with high circulating oxidized low-density lipoprotein in patients with type 2 diabetes mellitus and coronary artery disease
    • Lautamäki R, Rönnemaa T, Huupponen R, et al. Low serum adiponectin is associated with high circulating oxidized low-density lipoprotein in patients with type 2 diabetes mellitus and coronary artery disease. Metabolism. 2007;56:881-886.
    • (2007) Metabolism. , vol.56 , pp. 881-886
    • Lautamäki, R.1    Rönnemaa, T.2    Huupponen, R.3
  • 34
    • 0035957040 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macropages
    • Ouchi N, Kihara S, Arita Y, et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macropages. Circulation. 2001;103:1057-1063.
    • (2001) Circulation. , vol.103 , pp. 1057-1063
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3
  • 35
    • 0034014647 scopus 로고    scopus 로고
    • An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls
    • Okamoto Y, Arita Y, Nishida M, et al. An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls. Horm Metab Res. 2000;32:47-50.
    • (2000) Horm Metab Res. , vol.32 , pp. 47-50
    • Okamoto, Y.1    Arita, Y.2    Nishida, M.3
  • 36
    • 0038637251 scopus 로고    scopus 로고
    • Hypoadiponectinemia is closely linked to endothelial dysfunction in man
    • Shimabukuro M, Higa N, Asahi T, et al. Hypoadiponectinemia is closely linked to endothelial dysfunction in man. J Clin Endocrinol Metab. 2003;88:3236-3240.
    • (2003) J Clin Endocrinol Metab. , vol.88 , pp. 3236-3240
    • Shimabukuro, M.1    Higa, N.2    Asahi, T.3
  • 37
    • 0033826581 scopus 로고    scopus 로고
    • The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals
    • Kureishi Y, Luo Z, Shiojima I, et al. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nat Med. 2000;6:1004-1010.
    • (2000) Nat Med. , vol.6 , pp. 1004-1010
    • Kureishi, Y.1    Luo, Z.2    Shiojima, I.3
  • 38
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature. 2006;414:813-820.
    • (2006) Nature. , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 40
    • 3042672869 scopus 로고    scopus 로고
    • Simvastatin modulates angiotensin II signaling pathway by preventing Rac 1-mediated upregulation of p27
    • Zeng L, Xu H, Chew TL, et al. Simvastatin modulates angiotensin II signaling pathway by preventing Rac 1-mediated upregulation of p27. J Am Soc Nephrol. 2004;15:1711-1720.
    • (2004) J Am Soc Nephrol. , vol.15 , pp. 1711-1720
    • Zeng, L.1    Xu, H.2    Chew, T.L.3
  • 41
    • 38749088004 scopus 로고    scopus 로고
    • Differntial effect of atorvastatin and fenofibrate on plasma oxidized low-density lipoprotein, inflammation markers, and cell adhesion molecules in patients with type 2 diabetes mellitus
    • Hogue JC, Lamarche B, Tremblay AJ, et al. Differntial effect of atorvastatin and fenofibrate on plasma oxidized low-density lipoprotein, inflammation markers, and cell adhesion molecules in patients with type 2 diabetes mellitus. Metabolism. 2008;57:380-386.
    • (2008) Metabolism. , vol.57 , pp. 380-386
    • Hogue, J.C.1    Lamarche, B.2    Tremblay, A.J.3
  • 42
    • 36448983949 scopus 로고    scopus 로고
    • Lovastatin inhibits oxidized low-density lipoprotein-induced plasminogen activator inhibitor and transforming groth factor-β1 expression via a decrease in Ras/extracellular signal-regulated kinase activity in mesangial cells
    • Song CY, Kim BC, Lee HS. Lovastatin inhibits oxidized low-density lipoprotein-induced plasminogen activator inhibitor and transforming groth factor-β1 expression via a decrease in Ras/extracellular signal-regulated kinase activity in mesangial cells. Transl Res. 2008; 151:27-35.
    • (2008) Transl Res. , vol.151 , pp. 27-35
    • Song, C.Y.1    Kim, B.C.2    Lee, H.S.3
  • 43
    • 40649126121 scopus 로고    scopus 로고
    • Effects of pitavastatin on adiponectin in patients with hyperlipidemia
    • 2007-2008
    • Inami N, Nomura S, Shouzu A, et al. Effects of pitavastatin on adiponectin in patients with hyperlipidemia. Pathophysiol Haemost Thromb. 2007-2008;36:1-8.
    • Pathophysiol Haemost Thromb , vol.36 , pp. 1-8
    • Inami, N.1    Nomura, S.2    Shouzu, A.3
  • 44
    • 42949160571 scopus 로고    scopus 로고
    • Correlation between adiponectin and reduction of cell adhesion molecules after pitavastatin treatment in hyperlipidemic patients with type 2 diabetes mellitus
    • Nomura S, Shouzu A, Omoto S, et al. Correlation between adiponectin and reduction of cell adhesion molecules after pitavastatin treatment in hyperlipidemic patients with type 2 diabetes mellitus. Thromb Res. 2008;122:39-45.
    • (2008) Thromb Res. , vol.122 , pp. 39-45
    • Nomura, S.1    Shouzu, A.2    Omoto, S.3
  • 45
    • 7944237944 scopus 로고    scopus 로고
    • The role of fat tissue in the cholesterol lowering and the pleiotropic effects of statins-statins activate the generation of metabolically more capable adipocytes
    • Erol A. The role of fat tissue in the cholesterol lowering and the pleiotropic effects of statins-statins activate the generation of metabolically more capable adipocytes. Med Hypotheses. 2005;64:69-73.
    • (2005) Med Hypotheses. , vol.64 , pp. 69-73
    • Erol, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.