Oxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression through reactive oxygen species generation and ERK1/2 activation in 3T3-L1 adipocytes

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1811, Issue 3, 2011, Pages 153-162

  Kuniyasu, Akihiko ^a   Tokunaga, Mariko ^a   Yamamoto, Takashi ^a   Inoue, Shoko ^a   Obama, Keiko ^a   Kawahara, Kohichi ^a   Nakayama, Hitoshi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Adipocytes; Extracellular signal regulated kinase; Lysophosphatidylcholine; Oxidized LDL; Plasminogen activator inhibitor 1; Reactive oxygen species

Indexed keywords

LYSOPHOSPHATIDYLCHOLINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHOLIPASE A2; PLASMINOGEN ACTIVATOR INHIBITOR 1; REACTIVE OXYGEN METABOLITE;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; DOSE RESPONSE; ENZYME ACTIVATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; ANTIBODIES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; LIPOPROTEINS, LDL; LYSOPHOSPHATIDYLCHOLINES; METABOLIC SYNDROME X; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 3; PLASMINOGEN ACTIVATOR INHIBITOR 1; REACTIVE OXYGEN SPECIES; TIME FACTORS;

EID: 78651256770     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2010.11.011     Document Type: Article

References (51)

1. D. Steinberg Low density lipoprotein oxidation and its pathobiological significance J. Biol. Chem. 272 1997 20963 20966
2. J. Galle, T. Hansen-Hagge, C. Wanner, and S. Seibold Impact of oxidized low density lipoprotein on vascular cells Atherosclerosis 185 2006 219 226
3. H. Esterbauer, J. Gebicki, H. Puhl, and G. Jurgens The role of lipid peroxidation and antioxidants in oxidative modification of LDL Free Radic. Biol. Med. 13 1992 341 390
4. J.A. Berliner, and J.W. Heinecke The role of oxidized lipoproteins in atherogenesis Free Radic. Biol. Med. 20 1996 707 727
5. V.N. Bochkov Inflammatory profile of oxidized phospholipids Thromb. Haemost. 97 2007 348 354
6. G. Schmitz, and K. Ruebsaamen Metabolism and atherogenic disease association of lysophosphatidylcholine Atherosclerosis 208 2010 10 18
7. E. Porreca, C. Di Febbo, V. Moretta, A. Angelini, M.D. Guglielmi, M. Di Nisio, and F. Cuccurullo Circulating leptin is associated with oxidized LDL in postmenopausal women Atherosclerosis 175 2004 139 143
8. T. Weinbrenner, H. Schroder, V. Escurriol, M. Fito, R. Elosua, J. Vila, J. Marrugat, and M.I. Covas Circulating oxidized LDL is associated with increased waist circumference independent of body mass index in men and women Am. J. Clin. Nutr. 83 2006 30 35
9. P. Holvoet, D.H. Lee, M. Steffes, M. Gross, and D.R. Jacobs Jr. Association between circulating oxidized low-density lipoprotein and incidence of the metabolic syndrome JAMA 299 2008 2287 2293
10. K.J. Moore, and M.W. Freeman Scavenger receptors in atherosclerosis: beyond lipid uptake Arterioscler. Thromb. Vasc. Biol. 26 2006 1702 1711
11. A. Kuniyasu, S. Hayashi, and H. Nakayama Adipocytes recognize and degrade oxidized low density lipoprotein through CD36 Biochem. Biophys. Res. Commun. 295 2002 319 323
12. Z. Zhao, M.C. de Beer, L. Cai, R. Asmis, F.C. de Beer, W.J. de Villiers, and D.R. van der Westhuyzen Low-density lipoprotein from apolipoprotein E-deficient mice induces macrophage lipid accumulation in a CD36 and scavenger receptor class A-dependent manner Arterioscler. Thromb. Vasc. Biol. 25 2005 168 173
13. A. Kuniyasu, N. Ohgami, S. Hayashi, A. Miyazaki, S. Horiuchi, and H. Nakayama CD36-mediated endocytic uptake of advanced glycation end products (AGE) in mouse 3T3-L1 and human subcutaneous adipocytes FEBS Lett. 537 2003 85 90
14. S. Galic, J.S. Oakhill, and G.R. Steinberg Adipose tissue as an endocrine organ Mol. Cell. Endocrinol. 316 2010 129 139
15. L.F. Van Gaal, I.L. Mertens, and C.E. De Block Mechanisms linking obesity with cardiovascular disease Nature 444 2006 875 880
16. N. Rasouli, and P.A. Kern Adipocytokines and the metabolic complications of obesity J. Clin. Endocrinol. Metab. 93 2008 S64 S73
17. M.C. Alessi, M. Poggi, and I. Juhan-Vague Plasminogen activator inhibitor-1, adipose tissue and insulin resistance Curr. Opin. Lipidol. 18 2007 240 245
18. L.J. Ma, S.L. Mao, K.L. Taylor, T. Kanjanabuch, Y. Guan, Y. Zhang, N.J. Brown, L.L. Swift, O.P. McGuinness, D.H. Wasserman, D.E. Vaughan, and A.B. Fogo Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1 Diabetes 53 2004 336 346
19. M.C. Alessi, and I. Juhan-Vague PAI-1 and the metabolic syndrome: links, causes, and consequences Arterioscler. Thromb. Vasc. Biol. 26 2006 2200 2207
20. M.C. Alessi, F. Peiretti, P. Morange, M. Henry, G. Nalbone, and I. Juhan-Vague Production of plasminogen activator inhibitor 1 by human adipose tissue: possible link between visceral fat accumulation and vascular disease Diabetes 46 1997 860 867
21. I. Shimomura, T. Funahashi, M. Takahashi, K. Maeda, K. Kotani, T. Nakamura, S. Yamashita, M. Miura, Y. Fukuda, K. Takemura, K. Tokunaga, and Y. Matsuzawa Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity Nat. Med. 2 1996 800 803
22. P. Eriksson, S. Reynisdottir, F. Lonnqvist, V. Stemme, A. Hamsten, and P. Arner Adipose tissue secretion of plasminogen activator inhibitor-1 in non-obese and obese individuals Diabetologia 41 1998 65 71
23. F. Samad, K.T. Uysal, S.M. Wiesbrock, M. Pandey, G.S. Hotamisligil, and D.J. Loskutoff Tumor necrosis factor alpha is a key component in the obesity-linked elevation of plasminogen activator inhibitor 1 Proc. Natl. Acad. Sci. U.S.A. 96 1999 6902 6907
24. M. Pandey, G. Tuncman, G.S. Hotamisligil, and F. Samad Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1 Am. J. Pathol. 162 2003 933 941
25. F. Samad, K. Yamamoto, and D.J. Loskutoff Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-alpha and lipopolysaccharide J. Clin. Invest. 97 1996 37 46
26. S. Furukawa, T. Fujita, M. Shimabukuro, M. Iwaki, Y. Yamada, Y. Nakajima, O. Nakayama, M. Makishima, M. Matsuda, and I. Shimomura Increased oxidative stress in obesity and its impact on metabolic syndrome J. Clin. Invest. 114 2004 1752 1761
27. B. Chen, K.S. Lam, Y. Wang, D. Wu, M.C. Lam, J. Shen, L. Wong, R.L. Hoo, J. Zhang, and A. Xu Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes Biochem. Biophys. Res. Commun. 341 2006 549 556
28. M. Sakai, A. Miyazaki, H. Hakamata, T. Sasaki, S. Yui, M. Yamazaki, M. Shichiri, and S. Horiuchi Lysophosphatidylcholine plays an essential role in the mitogenic effect of oxidized low density lipoprotein on murine macrophages J. Biol. Chem. 269 1994 31430 31435
29. K. Kawahara, S. Oyadomari, T. Gotoh, S. Kohsaka, H. Nakayama, and M. Mori Induction of CHOP and apoptosis by nitric oxide in p53-deficient microglial cells FEBS Lett. 506 2001 135 139
30. Y. Unno, M. Sakai, Y. Sakamoto, A. Kuniyasu, H. Nakayama, R. Nagai, and S. Horiuchi Advanced glycation end products-modified proteins and oxidized LDL mediate down-regulation of leptin in mouse adipocytes via CD36 Biochem. Biophys. Res. Commun. 325 2004 151 156
31. A. Rudich, N. Kozlovsky, R. Potashnik, and N. Bashan Oxidant stress reduces insulin responsiveness in 3T3-L1 adipocytes Am. J. Physiol. 272 1997 E935 E940
32. E. Hamaguchi, T. Takamura, A. Shimizu, and Y. Nagai Tumor necrosis factor-alpha and troglitazone regulate plasminogen activator inhibitor type 1 production through extracellular signal-regulated kinase- and nuclear factor-κB-dependent pathways in cultured human umbilical vein endothelial cells J. Pharmacol. Exp. Ther. 307 2003 987 994
33. G.V. Sangle, R. Zhao, and G.X. Shen Transmembrane signaling pathway mediates oxidized low-density lipoprotein-induced expression of plasminogen activator inhibitor-1 in vascular endothelial cells Am. J. Physiol. Endocrinol. Metab. 295 2008 E1243 E1254
34. H.K. Hong, C.Y. Song, B.C. Kim, and H.S. Lee ERK contributes to the effects of Smad signaling on oxidized LDL-induced PAI-1 expression in human mesangial cells Transl. Res. 148 2006 171 179
35. N. Watanabe, J.W. Zmijewski, W. Takabe, M. Umezu-Goto, C. Le Goffe, A. Sekine, A. Landar, A. Watanabe, J. Aoki, H. Arai, T. Kodama, M.P. Murphy, R. Kalyanaraman, V.M. Darley-Usmar, and N. Noguchi Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells Am. J. Pathol. 168 2006 1737 1748
36. K. Yea, J. Kim, J.H. Yoon, T. Kwon, J.H. Kim, B.D. Lee, H.J. Lee, S.J. Lee, J.I. Kim, T.G. Lee, M.C. Baek, H.S. Park, K.S. Park, M. Ohba, P.G. Suh, and S.H. Ryu Lysophosphatidylcholine activates adipocyte glucose uptake and lowers blood glucose levels in murine models of diabetes J. Biol. Chem. 284 2009 33833 33840
37. M. Kamigaki, S. Sakaue, I. Tsujino, H. Ohira, D. Ikeda, N. Itoh, S. Ishimaru, Y. Ohtsuka, and M. Nishimura Oxidative stress provokes atherogenic changes in adipokine gene expression in 3T3-L1 adipocytes Biochem. Biophys. Res. Commun. 339 2006 624 632
38. Y. Uchida, K. Ohba, T. Yoshioka, K. Irie, T. Muraki, and Y. Maru Cellular carbonyl stress enhances the expression of plasminogen activator inhibitor-1 in rat white adipocytes via reactive oxygen species-dependent pathway J. Biol. Chem. 279 2004 4075 4083
39. R. Zhao, X. Ma, X. Xie, and G.X. Shen Involvement of NADPH oxidase in oxidized LDL-induced upregulation of heat shock factor-1 and plasminogen activator inhibitor-1 in vascular endothelial cells Am. J. Physiol. Endocrinol. Metab. 297 2009 E104 E111
40. J. Sun, Y. Xu, Z. Dai, and Y. Sun Intermittent high glucose stimulate MCP-l, IL-18, and PAI-1, but inhibit adiponectin expression and secretion in adipocytes dependent of ROS Cell. Biochem. Biophys. 55 2009 173 180
41. B. Chen, J. Wei, W. Wang, G. Cui, Y. Zhao, X. Zhu, M. Zhu, W. Guo, and J. Yu Identification of signaling pathways involved in aberrant production of adipokines in adipocytes undergoing oxidative stress Arch. Med. Res. 40 2009 241 248
42. P.C. Chui, H.P. Guan, M. Lehrke, and M.A. Lazar PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1 J. Clin. Invest. 115 2005 2244 2256
43. T. Yamakawa, S. Eguchi, Y. Yamakawa, E.D. Motley, K. Numaguchi, H. Utsunomiya, and T. Inagami Lysophosphatidylcholine stimulates MAP kinase activity in rat vascular smooth muscle cells Hypertension 31 1998 248 253
44. D. Bastelica, P. Morange, B. Berthet, H. Borghi, O. Lacroix, M. Grino, I. Juhan-Vague, and M.C. Alessi Stromal cells are the main plasminogen activator inhibitor-1-producing cells in human fat: evidence of differences between visceral and subcutaneous deposits Arterioscler. Thromb. Vasc. Biol. 22 2002 173 178
45. B.M. De Taeye, T. Novitskaya, L. Gleaves, J.W. Covington, and D.E. Vaughan Bone marrow plasminogen activator inhibitor-1 influences the development of obesity J. Biol. Chem. 281 2006 32796 32805
46. B. Scazzocchio, R. Vari, M. D'Archivio, C. Santangelo, C. Filesi, C. Giovannini, and R. Masella Oxidized LDL impair adipocyte response to insulin by activating serine/threonine kinases J. Lipid Res. 50 2009 832 845
47. C. Maziere, P. Morliere, R. Santus, V. Marcheux, C. Louandre, M.A. Conte, and J.C. Maziere Inhibition of insulin signaling by oxidized low density lipoprotein. Protective effect of the antioxidant Vitamin E Atherosclerosis 175 2004 23 30
48. S.P. Weisberg, D. McCann, M. Desai, M. Rosenbaum, R.L. Leibel, and A.W. Ferrante Jr. Obesity is associated with macrophage accumulation in adipose tissue J. Clin. Invest. 112 2003 1796 1808
49. H. Xu, G.T. Barnes, Q. Yang, G. Tan, D. Yang, C.J. Chou, J. Sole, A. Nichols, J.S. Ross, L.A. Tartaglia, and H. Chen Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance J. Clin. Invest. 112 2003 1821 1830
50. + effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity Nat. Med. 15 2009 914 920
51. G.M. Chisolm 3rd, S.L. Hazen, P.L. Fox, and M.K. Cathcart The oxidation of lipoproteins by monocytes-macrophages. Biochemical and biological mechanisms J. Biol. Chem. 274 1999 25959 25962