Glucose inhibits GABA release by pancreatic β-cells through an increase in GABA shunt activity

American Journal of Physiology - Endocrinology and Metabolism

Volumn 290, Issue 3, 2006, Pages

  Wang, Chen ^a   Kerckhofs, Karen ^a   Van De Casteele, Mark ^a   Smolders, Ilse ^b   Pipeleers, Daniel ^a   Ling, Zhidong ^a,c  

^a DIABETES RESEARCH CENTER   (Belgium)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c FREE UNIVERSITY OF BRUSSELS   (Belgium)

Author keywords

aminobutyric acid; aminobutyric acid transferase; Glutamine

Indexed keywords

2 OXOGLUTARIC ACID; 4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRIC ACID; GLUCOSE; GLUTAMATE DECARBOXYLASE; GLUTAMINE; INSULIN; MANNOHEPTULOSE; VIGABATRIN; ALPHA-KETOGLUTARIC ACID; ENZYME INHIBITOR;

4 AMINOBUTYRIC ACID RELEASE; 4 AMINOBUTYRIC ACID UPTAKE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATABOLISM; CELL FUNCTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; GABAERGIC TRANSMISSION; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; INSULIN RELEASE; MALE; MITOCHONDRION; NONHUMAN; PANCREAS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; METABOLISM; SECRETION; WISTAR RAT;

4-AMINOBUTYRATE TRANSAMINASE; ANIMALS; ENZYME INHIBITORS; GAMMA-AMINOBUTYRIC ACID; GLUCOSE; GLUTAMATE DECARBOXYLASE; GLUTAMINE; HUMANS; INSULIN-SECRETING CELLS; KETOGLUTARIC ACIDS; MALE; MANNOHEPTULOSE; RATS; RATS, WISTAR; VIGABATRIN;

EID: 33645065145     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00304.2005     Document Type: Article

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