Rapid, complex adaptation of transmitted HIV-1 full-length genomes in subtype C-infected individuals with differing disease progression

AIDS

Volumn 27, Issue 4, 2013, Pages 507-518

  Abrahams, Melissa Rose ^a   Treurnicht, Florette K ^a   Ngandu, Nobubelo K ^a   Goodier, Sarah A ^a   Marais, Jinny C ^a   Bredell, Helba ^a   Thebus, Ruwayhida ^a   De Assis Rosa, Debra ^b   Mlisana, Koleka ^c,d   Seoighe, Cathal ^e   Karim, Salim Abdool ^c   Gray, Clive M ^b   Williamson, Carolyn ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

^c UNIVERSITY OF KWAZULU NATAL   (South Africa)

^d UNIVERSITY OF KWAZULU NATAL   (South Africa)

^e NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

acute infection; Africa; cytotoxic T lymphocytes; genome; HIV 1; progression

Indexed keywords

EPITOPE;

ADAPTATION; ARTICLE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CYTOTOXIC T LYMPHOCYTE; DISEASE COURSE; FEMALE; GENE AMPLIFICATION; GENE SEQUENCE; GLYCOSYLATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 SUBTYPE C; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMORAL IMMUNITY; INFECTION CONTROL; PRIORITY JOURNAL; REVERTANT; VIRAL GENETICS; VIRUS LOAD; VIRUS TRANSMISSION;

ADULT; AMINO ACID SEQUENCE; DISEASE PROGRESSION; EPITOPES; EVOLUTION, MOLECULAR; FEMALE; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; GENOME, VIRAL; HIV INFECTIONS; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; POL GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; SEQUENCE ANALYSIS, DNA; SOUTH AFRICA; T-LYMPHOCYTES, CYTOTOXIC; TIME FACTORS; VIRAL LOAD; VIREMIA;

EID: 84873402115     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e32835cab64     Document Type: Article

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