Three short perioperative infusions of n-3 PUFAs reduce systemic inflammation induced by cardiopulmonary bypass surgery: A randomized controlled trial

American Journal of Clinical Nutrition

Volumn 97, Issue 2, 2013, Pages 246-254

  Berger, Mette M ^a   Delodder, Frederik ^a   Liaudet, Lucas ^a   Tozzi, Piergiorgio ^a   Schlaepfer, Juerg ^a   Chiolero, René L ^a   Tappy, Luc ^b  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYHEMOGLOBIN; CREATININE; FATTY ACID; FISH OIL; GLUCOSE; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; LACTIC ACID; OMEGAVEN; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CORE TEMPERATURE; CORONARY ARTERY BYPASS SURGERY; CREATININE BLOOD LEVEL; FATTY ACID BLOOD LEVEL; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HEART MUSCLE BIOPSY; HUMAN; HUMAN TISSUE; INFLAMMATION; LACTATE BLOOD LEVEL; LIPID COMPOSITION; MALE; OUTCOME ASSESSMENT; PERIOPERATIVE PERIOD; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE; TRIACYLGLYCEROL BLOOD LEVEL;

AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOOD PLATELETS; CARDIOPULMONARY BYPASS; CELL MEMBRANE; COHORT STUDIES; DOUBLE-BLIND METHOD; FAT EMULSIONS, INTRAVENOUS; FATTY ACIDS, OMEGA-3; FISH OILS; FOLLOW-UP STUDIES; HEART ATRIA; HEART DISEASES; HOSPITALS, UNIVERSITY; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; PERIOPERATIVE CARE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 84873386507     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.112.046573     Document Type: Article

References (38)

1. Calder PC. n23 Fatty acids and cardiovascular disease: evidence explained and mechanisms explored. Clin Sci (Lond) 2004; 107: 1-11.
2. Kris-Etherton PM, Harris WS, Appel LJ. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002; 106: 2747-57.
3. Mori TA, Woodman RJ. The independent effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors in humans. Curr Opin Clin Nutr Metab Care 2006; 9: 95-104.
4. Kromhout D, Yasuda S, Geleijnse JM, Shimokawa H. Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work? Eur Heart J 2012; 33: 436-43.
5. Pepe S, McLennan PL. Cardiac membrane fatty acid composition modulates myocardial oxygen consumption and postischemic recovery of contractile function. Circulation 2002; 105: 2303-8.
6. Albert CM, Campos H, Stampfer MJ, Ridker PM, Manson JE, Willett WC, Ma J. Blood levels of long-chain n23 fatty acids and the risk of sudden death. N Engl J Med 2002; 346: 1113-8.
7. GISSI-Prevenzione Investigators (Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico). Dietary supplementation with n23 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Lancet 1999; 354: 447-55.
8. Macchia A, Levantesi G, Franzosi MG, Geraci E, Maggioni AP, Marfisi R, Nicolosi GL, Schweiger C, Tavazzi L, Tognoni G, et al. Left ventricular systolic dysfunction, total mortality, and sudden death in patients with myocardial infarction treated with n23 polyunsaturated fatty acids. Eur J Heart Fail 2005; 7: 904-9.
9. Rubens FD, Mesana T. The inflammatory response to cardiopulmonary bypass: a therapeutic overview. Perfusion 2004; 19(suppl 1):S5-12.
10. Larmann J, Theilmeier G. Inflammatory response to cardiac surgery: cardiopulmonary bypass versus non-cardiopulmonary bypass surgery. Best Pract Res Clin Anaesthesiol 2004; 18: 425-38.
11. Khabar KS, elBarbary MA, Khouqeer F, Devol E, al-Gain S, al-Halees Z. Circulating endotoxin and cytokines after cardiopulmonary bypass: differential correlation with duration of bypass and systemic inflammatory response/multiple organ dysfunction syndromes. Clin Immunol Immunopathol 1997; 85: 97-103.
12. Sablotzki A, Dehne MG, Friedrich I, Grond S, Zickmann B, Muhling J, Silber RE, Czeslick EG. Different expression of cytokines in survivors and non-survivors from MODS following cardiovascular surgery. Eur J Med Res 2003; 8: 71-6.
13. Regner KR, Connolly HM, Schaff HV, Albright RC. Acute renal failure after cardiac surgery for carcinoid heart disease: incidence, risk factors, and prognosis. Am J Kidney Dis 2005; 45: 826-32.
14. Asimakopoulos G, Smith PL, Ratnatunga CP, Taylor KM. Lung injury and acute respiratory distress syndrome after cardiopulmonary bypass. Ann Thorac Surg 1999; 68: 1107-15.
15. Charman A, Muriithi EW, Milne E, Wheatley DJ, Armstrong RA, Belcher PR. Fish oil before cardiac surgery: neutrophil activation is unaffected but myocardial damage is moderated. Prostaglandins Leukot Essent Fatty Acids 2005; 72: 257-65.
16. Calò L, Bianconi L, Colivicchi F, Lamberti F, Loricchio ML, de Ruvo E, Meo A, Pandozi C, Staibano M, Santini M. n23 Fatty acids for the prevention of atrial fibrillation after coronary artery bypass surgery: a randomized, controlled trial. J Am Coll Cardiol 2005; 45: 1723-8.
17. Pittet YK, Berger MM, Pluess TT, Voirol P, Revelly JP, Tappy L, Chiolero RL. Blunting the response to endotoxin in healthy subjects: effects of various doses of intravenous fish oil. Intensive Care Med 2010; 36: 289-95.
18. Pluess TT, Hayoz D, Berger MM, Tappy L, Revelly JP, Michaeli B, Carpentier YA, Chiolero RL. Intravenous fish oil blunts the physiological response to endotoxin in healthy subjects. Intensive Care Med 2007; 33: 789-97.
19. Petter AH, Chiolero RL, Cassina T, Chassot PG, Muller XM, Revelly JP. Automatic "respirator/weaning" with adaptive support ventilation: the effect on duration of endotracheal intubation and patient management. Anesth Analg 2003; 97: 1743-50.
20. Roques F, Nashef SA, Michel P, Gauducheau E, de Vincentiis C, Baudet E, Cortina J, David M, Faichney A, Gavrielle F, et al. Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patients. Eur J Cardiothorac Surg 1999; 15: 816-22, discussion 222-3.
21. Kajdacsy-Balla Amaral AC, Andrade FM, Moreno R, Artigas A, Cantraine F, Vincent JL. Use of the sequential organ failure assessment score as a severity score. Intensive Care Med 2005; 31: 243-9.
22. Simoens C, Richelle M, Rossle C, Derluyn M, Deckelbaum RJ, Carpentier YA. Manipulation of tissue fatty acid profile by intravenous lipids in dogs. Clin Nutr 1995; 14: 177-85.
23. Vincent JL, Moreno R, Takala J, Willatts S, De Mendonca A, Bruining H, Reinhart CK, Suter PM, Thijs LG. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 1996; 22: 707-10.
24. Delodder F, Joseph C, Maravic P, Szostek T, Schaller MD, Berger MM, Revelly JP, Eggimann P. Tight glucose control managed by ICU nurses induces extremely low rates of hypoglycaemia. Crit Care 2011; 15 (suppl 1):395.
25. Tappy L, Berger MM, Schwarz JM, Revelly JP, Chioléro R. Metabolic effects of parenteral nutrition enriched with n23 polyunsaturated fatty acids in critically ill patients. Clin Nutr 2006; 25: 588-95.
26. Clive Landis R, Murkin JM, Stump DA, Baker RA, Arrowsmith JE, De Somer F, Dain SL, Dobkowski WB, Ellis JE, Falter F, et al. Consensus statement: minimal criteria for reporting the systemic inflammatory response to cardiopulmonary bypass. Heart Surg Forum 2010; 13: E116-23.
27. Katan MB, Deslypere JP, van Birgelen AP, Penders M, Zegwaard M. Kinetics of the incorporation of dietary fatty acids into serum cholesteryl esters, erythrocyte membranes, and adipose tissue: an 18-month controlled study. J Lipid Res 1997; 38: 2012-22.
28. Vidgren HM, Agren JJ, Schwab U, Rissanen T, Hanninen O, Uusitupa MI. Incorporation of n23 fatty acids into plasma lipid fractions, and erythrocyte membranes and platelets during dietary supplementation with fish, fish oil, and docosahexaenoic acid-rich oil among healthy young men. Lipids 1997; 32: 697-705.
29. Brown AJ, Pang E, Roberts DC. Persistent changes in the fatty acid composition of erythrocyte membranes after moderate intake of n23 polyunsaturated fatty acids: study design implications. Am J Clin Nutr 1991; 54: 668-73.
30. Calder PC. The relationship between the fatty acid composition of immune cells and their function. Prostaglandins Leukot Essent Fatty Acids 2008; 79: 101-8.
31. Carpentier YA, Hacquebard M, Portois L, Dupont IE, Deckelbaum RJ, Malaisse WJ. Rapid cellular enrichment of eicosapentaenoate after a single intravenous injection of a novel medium-chain triacylglycerol: fish-oil emulsion in humans. Am J Clin Nutr 2010; 91: 875-82.
32. Mozaffarian D, Geelen A, Brouwer IA, Geleijnse JM, Zock PL, Katan MB. Effect of fish oil on heart rate in humans: a meta-analysis of randomized controlled trials. Circulation 2005; 112: 1945-52.
33. Liu T, Korantzopoulos P, Shehata M, Li G, Wang X, Kaul S. Prevention of atrial fibrillation with omega-3 fatty acids: a meta-analysis of randomised clinical trials. Heart 2011; 97: 1034-40.
34. Rusca M, Oddo M, Schaller MD, Liaudet L. Carboxyhemoglobin formation as an unexpected side effect of inhaled nitric oxide therapy in severe acute respiratory distress syndrome. Crit Care Med 2004; 32: 2537-9.
35. Owens EO. Endogenous carbon monoxide production in disease. Clin Biochem 2010; 43: 1183-8.
36. Schober P, Kalmanowicz M, Schwarte LA, Loer SA. Cardiopulmonary bypass increases endogenous carbon monoxide production. J Cardiothorac Vasc Anesth 2009; 23: 802-6.
37. Calder PC, Jensen GL, Koletzko BV, Singer P, Wanten GJ. Lipid emulsions in parenteral nutrition of intensive care patients: current thinking and future directions. Intensive Care Med 2010; 36: 735-49.
38. Kroes R, Schaefer EJ, Squire RA, Williams GM. A review of the safety of DHA45-oil. Food Chem Toxicol 2003; 41: 1433-46.