Dietary antioxidants inhibit development of fatty streak lesions in the LDL receptor-deficient mouse

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 18, Issue 9, 1998, Pages 1506-1513

  Crawford, Richard S ^a   Kirk, Elizabeth A ^a   Rosenfeld, Michael E ^a   LeBoeuf, Renée C ^a   Chait, Alan ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Antioxidants; Atherosclerosis; Black tea; LDL

Indexed keywords

ANTIOXIDANT; LOW DENSITY LIPOPROTEIN RECEPTOR; PROBUCOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL ADHESION; CHOLESTEROL DIET; CONTROLLED STUDY; CYTOTOXICITY; DIETARY INTAKE; DRUG RECEPTOR BINDING; FOAM CELL; HYPERLIPIDEMIA; LIPID OXIDATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0031689195     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.18.9.1506     Document Type: Article

References (20)

1. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol: modifications of low density lipoprotein that increase its atherogenicity. N Engl J Med. 1989;320:916-924.
2. Berliner JA, Territo MC, Sevanian A, Romin S, Kim JA, Bamshad B, Esterson M, Fogelman AM. Minimally modified LDL stimulates monocyte endothelial interactions. J Clin Invest. 1990;85:1260-1266.
3. Morel DW, Hessler JR, Chisolm GM. Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid. J Lipid Res. 1983;24:1070-1076.
4. Henriksen T, Mahoney EM, Steinberg D. Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins. Proc Natl Acad Sci U S A. 1981;78:6499-6503.
5. Heinecke JW, Baker L, Rosen H, Chait A. Superoxide-mediated free radical modification of low density lipoprotein by arterial smooth muscle cells. J Clin Invest. 1986;77:757-761.
6. Hamilton TA, Ma GP, Chisolm GM. Oxidized low density lipoprotein suppresses the expression of tumor necrosis factor-alpha mRNA in stimulated murine peritoneal macrophages. J Immunol. 1990;144:2343-2350.
7. Maiden LT, Chait A, Raines EW, Ross R. The influence of oxidatively modified lipoproteins on expression of platelet-derived growth factor by human monocyte-derived macrophages. J Biol Chem. 1991;25:13901-13907.
8. Rajavashisth TB, Andalibi A, Territo MC, Berliner JA, Navab M, Fogelman AM, Lusis AJ. Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified LDL. Nature. 1990;344:254-257.
9. Carew TE, Schwenke DC, Steinberg D. Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that the antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic (WHHL) rabbit. Proc Natl Acad Sci U S A. 1987;84:7725-7729.
10. Chang MY, Sasahara M, Chait A, Raines EW, Ross R. Inhibition of hypercholesterolemia-induced atherosclerosis in the nonhuman primate by probucol, II: cellular composition and proliferation. Arterioscler Thromb Vasc Biol. 1995;15:1631-1640.
11. Bjoerkhem I, Henriksson-Freyschuss A, Breuer O, Diczfalusy U, Berglund L, Henriksson P. The antioxidant butylated hydroxytoluene protects against atherosclerosis. Arterioscler Thromb. 1991;11:15-22.
12. Tangirala RK, Casanada F, Miller E, Witztum JL, Steinberg D, Palinski W. Effect of the antioxidant N, N′-diphenyl-1,4-phenylenediamine (DPPD) on atherosclerosis in apo E-deficient mice. Arterioscler Thromb Vasc Biol. 1995;15:1625-1630.
13. Reaven PD, Khouw A, Beltz WF, Parthasarathy S, Witztum JL. Effect of dietary antioxidant combinations in humans: protection of LDL by vitamin E but not by β-carotene. Arterioscler Thromb. 1993;13:590-600.
14. Esterbauer H, Gebicki J, Puhl H, Jurgens G. The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radic Biol Med. 1992;13:341-390.
15. Williams RJ, Motteram JM, Sharp CH, Gallagher, PJ. Dietary vitamin E and the attenuation of early lesion development in modified Watanabe rabbits. Atherosclerosis. 1992;94:153-159.
16. Verlangieri AJ, Bush MJ. Effects of d- α-tocopherol supplementation on experimentally induced primate atherosclerosis. J Am Coll Nutr. 1992;11:131-138.
17. Kleinveld HA, Demacker PN, Stalenhoef AF. Comparative study on the effect of low-dose vitamin E and probucol on the susceptibility of LDL to oxidation and the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits. Arterioscler Thromb. 1994;14:1386-1391.
18. Willingham AK, Bolanos C, Bohannan E, Cenedella RJ. The effects of high levels of vitamin-E on the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit. J Nutr Biochem. 1993;4:651-654.
19. Shaish A, Daugherty A, O'Sullivan F, Schonfeld G, Heinecke JW. β-Carotene inhibits atherosclerosis in hypercholesterolemic rabbits. J Clin Invest. 1995;96:2075-2082.
20. Hertog MG, Feskens EJ, Hollman PC, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet. 1993;342:1007-1011.