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Volumn 56, Issue 1, 2013, Pages 106-115

Dual effect of the heart-targeting cytokine cardiotrophin-1 on glucose transport in cardiomyocytes

Author keywords

Cardiomyocytes; Cardiotrophin 1; Glucose transport; Insulin resistance

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CARDIOTROPHIN 1; CELL PROTEIN; GLUCOSE; GLUCOSE TRANSPORTER 4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; OLIGOMYCIN; PROTEIN AS160; PROTEIN KINASE B; PYRUVATE DEHYDROGENASE; STAT5 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; UNCLASSIFIED DRUG;

EID: 84873189237     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.12.015     Document Type: Article
Times cited : (14)

References (54)
  • 1
    • 84875064627 scopus 로고    scopus 로고
    • Regulation and dysregulation of glucose transport in cardiomyocytes
    • Montessuit C. Regulation and dysregulation of glucose transport in cardiomyocytes. Biochim Biophys Acta 2013, 10.1016/j.bbamcr.2012.08.009.
    • (2013) Biochim Biophys Acta
    • Montessuit, C.1
  • 2
    • 0035912954 scopus 로고    scopus 로고
    • Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis
    • Tian R., Abel E.D. Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis. Circulation 2001, 103:2961-2966.
    • (2001) Circulation , vol.103 , pp. 2961-2966
    • Tian, R.1    Abel, E.D.2
  • 3
    • 78149279712 scopus 로고    scopus 로고
    • AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
    • Russell R.R., Li J., Coven D.L., Pypaert M., Zechner C., Palmeri M., et al. AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J Clin Invest 2004, 114:495-503.
    • (2004) J Clin Invest , vol.114 , pp. 495-503
    • Russell, R.R.1    Li, J.2    Coven, D.L.3    Pypaert, M.4    Zechner, C.5    Palmeri, M.6
  • 4
    • 79151478555 scopus 로고    scopus 로고
    • Type 2 diabetes as an inflammatory disease
    • Donath M.Y., Shoelson S.E. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol 2011, 11:98-107.
    • (2011) Nat Rev Immunol , vol.11 , pp. 98-107
    • Donath, M.Y.1    Shoelson, S.E.2
  • 6
    • 34250315274 scopus 로고    scopus 로고
    • Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis
    • Fischer P., Hilfiker-Kleiner D. Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis. Basic Res Cardiol 2007, 102:279-297.
    • (2007) Basic Res Cardiol , vol.102 , pp. 279-297
    • Fischer, P.1    Hilfiker-Kleiner, D.2
  • 7
    • 0035813098 scopus 로고    scopus 로고
    • The cytoprotective effects of the glycoprotein 130 receptor-coupled cytokine, cardiotrophin-1, require activation of NF-κB
    • Craig R., Wagner M., McCardle T., Craig A.G., Glembotski C.C. The cytoprotective effects of the glycoprotein 130 receptor-coupled cytokine, cardiotrophin-1, require activation of NF-κB. J Biol Chem 2001, 276:37621-37629.
    • (2001) J Biol Chem , vol.276 , pp. 37621-37629
    • Craig, R.1    Wagner, M.2    McCardle, T.3    Craig, A.G.4    Glembotski, C.C.5
  • 8
    • 33644823811 scopus 로고    scopus 로고
    • Leukaemia inhibitory factor stimulates glucose transport in isolated cardiomyocytes and induces insulin resistance after chronic exposure
    • Florholmen G., Thoresen G., Rustan A., Jensen J., Christensen G., Aas V. Leukaemia inhibitory factor stimulates glucose transport in isolated cardiomyocytes and induces insulin resistance after chronic exposure. Diabetologia 2006, 49:724-731.
    • (2006) Diabetologia , vol.49 , pp. 724-731
    • Florholmen, G.1    Thoresen, G.2    Rustan, A.3    Jensen, J.4    Christensen, G.5    Aas, V.6
  • 12
    • 0019175175 scopus 로고
    • Culture of the terminally differentiated adult cardiac muscle cell: a light and scanning electron microscope study
    • Claycomb W., Palazzo M. Culture of the terminally differentiated adult cardiac muscle cell: a light and scanning electron microscope study. Dev Biol 1980, 80:466-482.
    • (1980) Dev Biol , vol.80 , pp. 466-482
    • Claycomb, W.1    Palazzo, M.2
  • 13
    • 0025291912 scopus 로고
    • Reexpression of α-smooth muscle actin isoform in cultured adult rat cardiomyocytes
    • Eppenberger-Eberhardt M., Flamme I., Kurer V., Eppenberger H.M. Reexpression of α-smooth muscle actin isoform in cultured adult rat cardiomyocytes. Dev Biol 1990, 139:269-278.
    • (1990) Dev Biol , vol.139 , pp. 269-278
    • Eppenberger-Eberhardt, M.1    Flamme, I.2    Kurer, V.3    Eppenberger, H.M.4
  • 14
    • 4644327146 scopus 로고    scopus 로고
    • Insulin resistance in adult cardiomyocytes undergoing dedifferentiation: role of GLUT4 expression and translocation
    • Rosenblatt-Velin N., Lerch R., Papageorgiou I., Montessuit C. Insulin resistance in adult cardiomyocytes undergoing dedifferentiation: role of GLUT4 expression and translocation. FASEB J 2004, 18:872-874.
    • (2004) FASEB J , vol.18 , pp. 872-874
    • Rosenblatt-Velin, N.1    Lerch, R.2    Papageorgiou, I.3    Montessuit, C.4
  • 15
    • 40849131138 scopus 로고    scopus 로고
    • Nuclear receptors agonists improve insulin responsiveness in cultured cardiomyocytes through enhanced signaling and preserved cytoskeletal architecture
    • Montessuit C., Papageorgiou I., Lerch R. Nuclear receptors agonists improve insulin responsiveness in cultured cardiomyocytes through enhanced signaling and preserved cytoskeletal architecture. Endocrinology 2008, 149:1064-1074.
    • (2008) Endocrinology , vol.149 , pp. 1064-1074
    • Montessuit, C.1    Papageorgiou, I.2    Lerch, R.3
  • 17
    • 0035827663 scopus 로고    scopus 로고
    • Insulin Induction of SOCS-2 and SOCS-3 mRNA Expression in C2C12 Skeletal Muscle Cells Is Mediated by Stat5
    • Sadowski C.L., Choi T.-S., Le M., Wheeler T.T., Wang L.-H., Sadowski H.B. Insulin Induction of SOCS-2 and SOCS-3 mRNA Expression in C2C12 Skeletal Muscle Cells Is Mediated by Stat5. J Biol Chem 2001, 276:20703-20710.
    • (2001) J Biol Chem , vol.276 , pp. 20703-20710
    • Sadowski, C.L.1    Choi, T.-S.2    Le, M.3    Wheeler, T.T.4    Wang, L.-H.5    Sadowski, H.B.6
  • 20
    • 0037853260 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes
    • Senn J.J., Klover P.J., Nowak I.A., Zimmers T.A., Koniaris L.G., Furlanetto R.W., et al. Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes. J Biol Chem 2003, 278:13740-13746.
    • (2003) J Biol Chem , vol.278 , pp. 13740-13746
    • Senn, J.J.1    Klover, P.J.2    Nowak, I.A.3    Zimmers, T.A.4    Koniaris, L.G.5    Furlanetto, R.W.6
  • 21
    • 37249093922 scopus 로고    scopus 로고
    • SOCS proteins causing trouble in insulin action
    • Lebrun P., Van Obberghen E. SOCS proteins causing trouble in insulin action. Acta Physiol 2008, 192:29-36.
    • (2008) Acta Physiol , vol.192 , pp. 29-36
    • Lebrun, P.1    Van Obberghen, E.2
  • 22
    • 43149095374 scopus 로고    scopus 로고
    • Discovery of chromone-based inhibitors of the transcription factor STAT5
    • Müller J., Sperl B., Reindl W., Kiessling A., Berg T. Discovery of chromone-based inhibitors of the transcription factor STAT5. Chembiochem 2008, 9:723-727.
    • (2008) Chembiochem , vol.9 , pp. 723-727
    • Müller, J.1    Sperl, B.2    Reindl, W.3    Kiessling, A.4    Berg, T.5
  • 23
    • 0036333737 scopus 로고    scopus 로고
    • Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B
    • Scheid M.P., Marignani P.A., Woodgett J.R. Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B. Mol Cell Biol 2002, 22:6247-6260.
    • (2002) Mol Cell Biol , vol.22 , pp. 6247-6260
    • Scheid, M.P.1    Marignani, P.A.2    Woodgett, J.R.3
  • 24
    • 0037151026 scopus 로고    scopus 로고
    • A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain
    • Kane S., Sano H., Liu S.C.H., Asara J.M., Lane W.S., Garner C.C., et al. A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain. J Biol Chem 2002, 277:22115-22118.
    • (2002) J Biol Chem , vol.277 , pp. 22115-22118
    • Kane, S.1    Sano, H.2    Liu, S.C.H.3    Asara, J.M.4    Lane, W.S.5    Garner, C.C.6
  • 25
    • 0037677096 scopus 로고    scopus 로고
    • Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation
    • Sano H., Kane S., Sano E., Miinea C.P., Asara J.M., Lane W.S., et al. Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation. J Biol Chem 2003, 278:14599-14602.
    • (2003) J Biol Chem , vol.278 , pp. 14599-14602
    • Sano, H.1    Kane, S.2    Sano, E.3    Miinea, C.P.4    Asara, J.M.5    Lane, W.S.6
  • 26
    • 33747039008 scopus 로고    scopus 로고
    • Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle
    • Kramer H.F., Witczak C.A., Fujii N., Jessen N., Taylor E.B., Arnolds D.E., et al. Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle. Diabetes 2006, 55:2067-2076.
    • (2006) Diabetes , vol.55 , pp. 2067-2076
    • Kramer, H.F.1    Witczak, C.A.2    Fujii, N.3    Jessen, N.4    Taylor, E.B.5    Arnolds, D.E.6
  • 27
    • 33847062845 scopus 로고    scopus 로고
    • The Rab GTPase-activating protein AS160 integrates Akt, protein kinase C, and AMP-activated protein kinase signals regulating GLUT4 traffic
    • Thong F.S.L., Bilan P.J., Klip A. The Rab GTPase-activating protein AS160 integrates Akt, protein kinase C, and AMP-activated protein kinase signals regulating GLUT4 traffic. Diabetes 2007, 56:414-423.
    • (2007) Diabetes , vol.56 , pp. 414-423
    • Thong, F.S.L.1    Bilan, P.J.2    Klip, A.3
  • 28
    • 34147152841 scopus 로고    scopus 로고
    • Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade
    • Sanders M.J., Grondin P.O., Hegarty B.D., Snowden M.A., Carling D. Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade. Biochem J 2007, 403:139-148.
    • (2007) Biochem J , vol.403 , pp. 139-148
    • Sanders, M.J.1    Grondin, P.O.2    Hegarty, B.D.3    Snowden, M.A.4    Carling, D.5
  • 29
    • 23044432463 scopus 로고    scopus 로고
    • Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase
    • Hawley S.A., Pan D.A., Mustard K.J., Ross L., Bain J., Edelman A.M., et al. Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab 2005, 2:9-19.
    • (2005) Cell Metab , vol.2 , pp. 9-19
    • Hawley, S.A.1    Pan, D.A.2    Mustard, K.J.3    Ross, L.4    Bain, J.5    Edelman, A.M.6
  • 31
    • 45149088263 scopus 로고    scopus 로고
    • 2+-dependent signaling pathways regulating FA uptake and oxidation in contracting rodent muscle
    • 2+-dependent signaling pathways regulating FA uptake and oxidation in contracting rodent muscle. J Appl Physiol 2008, 104:1366-1373.
    • (2008) J Appl Physiol , vol.104 , pp. 1366-1373
    • Raney, M.A.1    Turcotte, L.P.2
  • 32
    • 0037013222 scopus 로고    scopus 로고
    • STO-609, a specific inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase
    • Tokumitsu H., Inuzuka H., Ishikawa Y., Ikeda M., Saji I., Kobayashi R. STO-609, a specific inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase. J Biol Chem 2002, 277:15813-15818.
    • (2002) J Biol Chem , vol.277 , pp. 15813-15818
    • Tokumitsu, H.1    Inuzuka, H.2    Ishikawa, Y.3    Ikeda, M.4    Saji, I.5    Kobayashi, R.6
  • 34
    • 80054120475 scopus 로고    scopus 로고
    • HIF-1-mediated up-regulation of cardiotrophin-1 is involved in the survival response of cardiomyocytes to hypoxia
    • Robador P.A., San José G., Rodríguez C., Guadall A., Moreno M.U., Beaumont J., et al. HIF-1-mediated up-regulation of cardiotrophin-1 is involved in the survival response of cardiomyocytes to hypoxia. Cardiovasc Res 2011, 92:247-255.
    • (2011) Cardiovasc Res , vol.92 , pp. 247-255
    • Robador, P.A.1    San José, G.2    Rodríguez, C.3    Guadall, A.4    Moreno, M.U.5    Beaumont, J.6
  • 35
  • 36
    • 0034634297 scopus 로고    scopus 로고
    • Calmodulin kinases II and IV and calcineurin are involved in leukemia inhibitory factor-induced cardiac hypertrophy in rats
    • Kato T., Sano M., Miyoshi S., Sato T., Hakuno D., Ishida H., et al. Calmodulin kinases II and IV and calcineurin are involved in leukemia inhibitory factor-induced cardiac hypertrophy in rats. Circ Res 2000, 87:937-945.
    • (2000) Circ Res , vol.87 , pp. 937-945
    • Kato, T.1    Sano, M.2    Miyoshi, S.3    Sato, T.4    Hakuno, D.5    Ishida, H.6
  • 37
    • 84855702837 scopus 로고    scopus 로고
    • Glycoprotein 130 cytokine signal as a therapeutic target against cardiovascular diseases
    • Fujio Y., Maeda M., Mohri T., Obana M., Iwakura T., Hayama A., et al. Glycoprotein 130 cytokine signal as a therapeutic target against cardiovascular diseases. J Pharmacol Sci 2011, 117:213-222.
    • (2011) J Pharmacol Sci , vol.117 , pp. 213-222
    • Fujio, Y.1    Maeda, M.2    Mohri, T.3    Obana, M.4    Iwakura, T.5    Hayama, A.6
  • 38
    • 33750859187 scopus 로고    scopus 로고
    • Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase
    • Carey A.L., Steinberg G.R., Macaulay S.L., Thomas W.G., Holmes A.G., Ramm G., et al. Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase. Diabetes 2006, 55:2688-2697.
    • (2006) Diabetes , vol.55 , pp. 2688-2697
    • Carey, A.L.1    Steinberg, G.R.2    Macaulay, S.L.3    Thomas, W.G.4    Holmes, A.G.5    Ramm, G.6
  • 39
    • 64649092672 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor stimulates muscle glucose uptake by a PI3-kinase-dependent pathway that is impaired with obesity
    • Steinberg G.R., Watt M.J., Ernst M., Birnbaum M.J., Kemp B.E., Jørgensen S.B. Ciliary neurotrophic factor stimulates muscle glucose uptake by a PI3-kinase-dependent pathway that is impaired with obesity. Diabetes 2009, 58:829-839.
    • (2009) Diabetes , vol.58 , pp. 829-839
    • Steinberg, G.R.1    Watt, M.J.2    Ernst, M.3    Birnbaum, M.J.4    Kemp, B.E.5    Jørgensen, S.B.6
  • 40
    • 33646570554 scopus 로고    scopus 로고
    • CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK
    • Watt M.J., Dzamko N., Thomas W.G., Rose-John S., Ernst M., Carling D., et al. CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK. Nat Med 2006, 12:541-548.
    • (2006) Nat Med , vol.12 , pp. 541-548
    • Watt, M.J.1    Dzamko, N.2    Thomas, W.G.3    Rose-John, S.4    Ernst, M.5    Carling, D.6
  • 41
    • 0346098034 scopus 로고    scopus 로고
    • Threshold effects of glucose transporter-4 (GLUT4) deficiency on cardiac glucose uptake and development of hypertrophy
    • Kaczmarczyk S.J., Andrikopoulos S., Favaloro J., Domenighetti A.A., Dunn A., Ernst M., et al. Threshold effects of glucose transporter-4 (GLUT4) deficiency on cardiac glucose uptake and development of hypertrophy. J Mol Endocrinol 2003, 31:449-459.
    • (2003) J Mol Endocrinol , vol.31 , pp. 449-459
    • Kaczmarczyk, S.J.1    Andrikopoulos, S.2    Favaloro, J.3    Domenighetti, A.A.4    Dunn, A.5    Ernst, M.6
  • 42
    • 12344329352 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-3 provides a novel interface in the cross-talk between angiotensin II and insulin signaling systems
    • Calegari V.C., Alves M., Picardi P.K., Inoue R.Y., Franchini K.G., Saad M.J.A., et al. Suppressor of cytokine signaling-3 provides a novel interface in the cross-talk between angiotensin II and insulin signaling systems. Endocrinology 2005, 146:579-588.
    • (2005) Endocrinology , vol.146 , pp. 579-588
    • Calegari, V.C.1    Alves, M.2    Picardi, P.K.3    Inoue, R.Y.4    Franchini, K.G.5    Saad, M.J.A.6
  • 43
    • 84859453681 scopus 로고    scopus 로고
    • Differential regulation of stimulated glucose transport by free fatty acids and PPARα or δ agonists in cardiac myocytes
    • Asrih M., Lerch R., Papageorgiou I., Pellieux C., Montessuit C. Differential regulation of stimulated glucose transport by free fatty acids and PPARα or δ agonists in cardiac myocytes. Am J Physiol Endocrinol Metab 2012, 302:E872-E884.
    • (2012) Am J Physiol Endocrinol Metab , vol.302
    • Asrih, M.1    Lerch, R.2    Papageorgiou, I.3    Pellieux, C.4    Montessuit, C.5
  • 44
    • 33745684376 scopus 로고    scopus 로고
    • AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B
    • Bertrand L., Ginion A., Beauloye C., Hebert A.D., Guigas B., Hue L., et al. AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B. Am J Physiol Heart Circ Physiol 2006, 291:H239-H250.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Bertrand, L.1    Ginion, A.2    Beauloye, C.3    Hebert, A.D.4    Guigas, B.5    Hue, L.6
  • 45
    • 84856755004 scopus 로고    scopus 로고
    • Phosphorylation of the insulin receptor by AMP-activated protein kinase (AMPK) promotes ligand-independent activation of the insulin signalling pathway in rodent muscle
    • Chopra I., Li H.F., Wang H., Webster K.A. Phosphorylation of the insulin receptor by AMP-activated protein kinase (AMPK) promotes ligand-independent activation of the insulin signalling pathway in rodent muscle. Diabetologia 2012, 55:783-794.
    • (2012) Diabetologia , vol.55 , pp. 783-794
    • Chopra, I.1    Li, H.F.2    Wang, H.3    Webster, K.A.4
  • 46
    • 0345059046 scopus 로고    scopus 로고
    • A role for calcium/calmodulin kinase in insulin stimulated glucose transport
    • Wright D.C., Fick C.A., Olesen J.B., Lim K., Barnes B.R., Craig B.W. A role for calcium/calmodulin kinase in insulin stimulated glucose transport. Life Sci 2004, 74:815-825.
    • (2004) Life Sci , vol.74 , pp. 815-825
    • Wright, D.C.1    Fick, C.A.2    Olesen, J.B.3    Lim, K.4    Barnes, B.R.5    Craig, B.W.6
  • 48
  • 49
    • 4444381927 scopus 로고    scopus 로고
    • Regulation of glucose transporters expression in cardiac myocytes: p38 MAPK is a strong inductor of GLUT4
    • Montessuit C., Rosenblatt-Velin N., Papageorgiou I., Campos L., Pellieux C., Palma T., et al. Regulation of glucose transporters expression in cardiac myocytes: p38 MAPK is a strong inductor of GLUT4. Cardiovasc Res 2004, 64:94-104.
    • (2004) Cardiovasc Res , vol.64 , pp. 94-104
    • Montessuit, C.1    Rosenblatt-Velin, N.2    Papageorgiou, I.3    Campos, L.4    Pellieux, C.5    Palma, T.6
  • 50
    • 79957937929 scopus 로고    scopus 로고
    • Targeting fatty acid and carbohydrate oxidation - a novel therapeutic intervention in the ischemic and failing heart
    • Jaswal J.S., Keung W., Wang W., Ussher J.R., Lopaschuk G.D. Targeting fatty acid and carbohydrate oxidation - a novel therapeutic intervention in the ischemic and failing heart. Biochim Biophys Acta 2011, 1813:1333-1350.
    • (2011) Biochim Biophys Acta , vol.1813 , pp. 1333-1350
    • Jaswal, J.S.1    Keung, W.2    Wang, W.3    Ussher, J.R.4    Lopaschuk, G.D.5
  • 51
    • 68049093113 scopus 로고    scopus 로고
    • New insights into myocardial glucose metabolism: surviving under stress
    • Patterson B., Fields A.V., Shannon R.P. New insights into myocardial glucose metabolism: surviving under stress. Curr Opin Clin Nutr Metab Care 2009, 12:424-430.
    • (2009) Curr Opin Clin Nutr Metab Care , vol.12 , pp. 424-430
    • Patterson, B.1    Fields, A.V.2    Shannon, R.P.3
  • 53
    • 66049097308 scopus 로고    scopus 로고
    • Activation of a HIF1α-PPARγ axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy
    • Krishnan J., Suter M., Windak R., Krebs T., Felley A., Montessuit C., et al. Activation of a HIF1α-PPARγ axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy. Cell Metab 2009, 9:512-524.
    • (2009) Cell Metab , vol.9 , pp. 512-524
    • Krishnan, J.1    Suter, M.2    Windak, R.3    Krebs, T.4    Felley, A.5    Montessuit, C.6
  • 54
    • 0030846315 scopus 로고    scopus 로고
    • Effects of wortmannin on insulin- and ischemia-induced stimulation of GLUT4 translocation and FDG uptake in perfused rat hearts
    • Egert S., Nguyen N., Brosius F.C.I., Schwaiger M. Effects of wortmannin on insulin- and ischemia-induced stimulation of GLUT4 translocation and FDG uptake in perfused rat hearts. Cardiovasc Res 1997, 35:283-293.
    • (1997) Cardiovasc Res , vol.35 , pp. 283-293
    • Egert, S.1    Nguyen, N.2    Brosius, F.C.I.3    Schwaiger, M.4


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