Chronic metformin associated cardioprotection against infarction: Not just a glucose lowering phenomenon

Cardiovascular Drugs and Therapy

Volumn 27, Issue 1, 2013, Pages 5-16

  Whittington, Hannah J ^a   Hall, Andrew R ^a   McLaughlin, Catarina P ^a   Hausenloy, Derek J ^a   Yellon, Derek M ^a   Mocanu, Mihaela M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cardioprotection; Ischemia reperfusion injury; Metformin; PGC 1

Indexed keywords

ADENYLATE KINASE; METFORMIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG MECHANISM; HEART INFARCTION; HEART MITOCHONDRION; HEART PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; TREATMENT RESPONSE;

AGING; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; CARDIOTONIC AGENTS; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOGLYCEMIC AGENTS; MALE; METFORMIN; MICROSCOPY, ELECTRON; MITOCHONDRIA, HEART; MYOCARDIAL INFARCTION; MYOCARDIUM; PROTEIN KINASES; RATS; RATS, WISTAR; RNA-BINDING PROTEINS; TRANSCRIPTION FACTORS;

EID: 84873056313     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-012-6425-x     Document Type: Article

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