Heat shock transcription factor-1 suppresses apoptotic cell death and ROS generation in 3-nitropropionic acid-stimulated striatal cells

Molecular and Cellular Biochemistry

Volumn 375, Issue 1-2, 2013, Pages 59-67

  Choi, Yong Joon ^a   Om, Ji Yeon ^a   Kim, Nam Ho ^a   Chang, Ji Eun ^a   Park, Jun Ho ^a   Kim, Ji Young ^a   Lee, Hee Jae ^a   Kim, Sung Soo ^a   Chun, Wanjoo ^a  

^a Kangwon National University   (South Korea)

Author keywords

Heat shock protein 70 (HSP 70); Heat shock transcription factor 1 (HSF 1); Huntington's disease; Reactive oxygen species (ROS)

Indexed keywords

3 NITROPROPIONIC ACID; HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR 1; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; ATTENUATION; DOWN REGULATION; HUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN TARGETING;

ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE; CELL SURVIVAL; DNA-BINDING PROTEINS; GENE EXPRESSION; HSP70 HEAT-SHOCK PROTEINS; HUMANS; HUNTINGTON DISEASE; METHYLENE BLUE; MICE; NEOSTRIATUM; NITRO COMPOUNDS; POLY(ADP-RIBOSE) POLYMERASES; PROPIONATES; REACTIVE OXYGEN SPECIES; SUCCINATE DEHYDROGENASE; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 84873055636     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1528-z     Document Type: Article

References (33)

1. Stephanou A, Isenberg DA, Nakajima K, Latchman DS (1999) Signal transducer and activator of transcription-1 and heat shock factor-1 interact and activate the transcription of the Hsp-70 and Hsp-90beta gene promoters. J Biol Chem 274(3):1723-1728
2. Santoro MG (2000) Heat shock factors and the control of the stress response. Biochem Pharmacol 59(1):55-63
3. Zhang L, Jiang H, Gao X, Zou Y, Liu M, Liang Y, Yu Y, Zhu W, Chen H, Ge J (2011) Heat shock transcription factor-1 inhibits H2O2-induced apoptosis via down-regulation of reactive oxygen species in cardiac myocytes. Mol Cell Biochem 347(1-2):21-28
4. Rinaldi Tosi ME, Bocanegra V, Manucha W, Gil Lorenzo A, Valles PG (2011) The Nrf2-Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO). Cell Stress Chaperones 16(1):57-68
5. Manucha W, Valles PG (2008) Cytoprotective role of nitric oxide associated with Hsp70 expression in neonatal obstructive nephropathy. Nitric Oxide 18(3):204-215
6. Holmberg CI, Illman SA, Kallio M, Mikhailov A, Sistonen L (2000) Formation of nuclear HSF1 granules varies depending on stress stimuli. Cell Stress Chaperones 5(3):219-228
7. Xia W, Vilaboa N, Martin JL, Mestril R, Guo Y, Voellmy R (1999) Modulation of tolerance by mutant heat shock transcription factors. Cell Stress Chaperones 4(1):8-18
8. Fujikake N, Nagai Y, Popiel HA, Okamoto Y, Yamaguchi M, Toda T (2008) Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones. J Biol Chem 283(38):26188-26197
9. Cummings CJ, Mancini MA, Antalffy B, DeFranco DB, Orr HT, Zoghbi HY (1998) Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1. Nat Genet 19(2):148-154
10. Kobayashi Y, Kume A, Li M, Doyu M, Hata M, Ohtsuka K, Sobue G (2000) Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with expanded polyglutamine tract. J Biol Chem 275(12):8772-8778
11. Wyttenbach A, Swartz J, Kita H, Thykjaer T, Carmichael J, Bradley J, Brown R, Maxwell M, Schapira A, Orntoft TF, Kato K, Rubinsztein DC (2001) Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Hum Mol Genet 10(17):1829-1845
12. Chen LJ, Su XW, Qiu PX, Huang YJ, Yan GM (2004) Thermal preconditioning protected cerebellar granule neurons of rats by modulating HSP70 expression. Acta Pharmacol Sin 25(4):458-461
13. Kabakov AE, Budagova KR, Bryantsev AL, Latchman DS (2003) Heat shock protein 70 or heat shock protein 27 overexpressed in human endothelial cells during posthypoxic reoxygenation can protect from delayed apoptosis. Cell Stress Chaperones 8(4):335-347
14. Brouillet E, Conde F, Beal MF, Hantraye P (1999) Replicating Huntington's disease phenotype in experimental animals. Prog Neurobiol 59(5):427-468
15. Dedeoglu A, Ferrante RJ, Andreassen OA, Dillmann WH, Beal MF (2002) Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid. Exp Neurol 176(1):262-265
16. Wang AM, Morishima Y, Clapp KM, Peng HM, Pratt WB, Gestwicki JE, Osawa Y, Lieberman AP (2010) Inhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation. J Biol Chem 285(21):15714-15723
17. Wyttenbach A (2004) Role of heat shock proteins during polyglutamine neurodegeneration: mechanisms and hypothesis. J Mol Neurosci 23(1-2):69-96
18. Muchowski PJ, Wacker JL (2005) Modulation of neurodegeneration by molecular chaperones. Nat Rev Neurosci 6(1):11-22
19. Choudhury S, Bae S, Ke Q, Lee JY, Kim J, Kang PM (2011) Mitochondria to nucleus translocation of AIF in mice lacking Hsp70 during ischemia/reperfusion. Basic Res Cardiol 106(3):397-407
20. Gurbuxani S, Schmitt E, Cande C, Parcellier A, Hammann A, Daugas E, Kouranti I, Spahr C, Pance A, Kroemer G, Garrido C (2003) Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor. Oncogene 22(43):6669-6678
21. Ravagnan L, Gurbuxani S, Susin SA, Maisse C, Daugas E, Zamzami N, Mak T, Jaattela M, Penninger JM, Garrido C, Kroemer G (2001) Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat Cell Biol 3(9):839-843
22. Mosser DD, Caron AW, Bourget L, Denis-Larose C, Massie B (1997) Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis. Mol Cell Biol 17(9):5317-5327
23. Ciocca DR, Clark GM, Tandon AK, Fuqua SA, Welch WJ, McGuire WL (1993) Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: prognostic implications. J Natl Cancer Inst 85(7):570-574
24. Dive C, Hickman JA (1991) Drug-target interactions: only the first step in the commitment to a programmed cell death? Br J Cancer 64(1):192-196
25. Seo JS, Park YM, Kim JI, Shim EH, Kim CW, Jang JJ, Kim SH, Lee WH (1996) T cell lymphoma in transgenic mice expressing the human Hsp70 gene. Biochem Biophys Res Commun 218(2):582-587
26. Wei YQ, Zhao X, Kariya Y, Teshigawara K, Uchida A (1995) Inhibition of proliferation and induction of apoptosis by abrogation of heat-shock protein (HSP) 70 expression in tumor cells. Cancer Immunol Immunother 40(2):73-78
27. Haldimann P, Muriset M, Vigh L, Goloubinoff P (2011) The novel hydroxylamine derivative NG-094 suppresses polyglutamine protein toxicity in Caenorhabditis elegans. J Biol Chem 286(21):18784-18794
28. Wacker JL, Huang SY, Steele AD, Aron R, Lotz GP, Nguyen Q, Giorgini F, Roberson ED, Lindquist S, Masliah E, Muchowski PJ (2009) Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease. J Neurosci 29(28):9104-9114
29. Kieran D, Kalmar B, Dick JR, Riddoch-Contreras J, Burnstock G, Greensmith L (2004) Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice. Nat Med 10(4):402-405
30. Yan LJ, Rajasekaran NS, Sathyanarayanan S, Benjamin IJ (2005) Mouse HSF1 disruption perturbs redox state and increases mitochondrial oxidative stress in kidney. Antioxid Redox Signal 7(3-4):465-471
31. Xiao X, Benjamin IJ (1999) Stress-response proteins in cardiovascular disease. Am J Hum Genet 64(3):685-690
32. Murapa P, Gandhapudi S, Skaggs HS, Sarge KD, Woodward JG (2007) Physiological fever temperature induces a protective stress response in T lymphocytes mediated by heat shock factor-1 (HSF1). J Immunol 179(12):8305-8312
33. Sarge KD, Murphy SP, Morimoto RI (1993) Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress. Mol Cell Biol 13(3):1392-1407