G-protein-coupled heteromers: Regulation in disease

Methods in Enzymology

Volumn 521, Issue , 2013, Pages 219-238

  Gomes, Ivone ^a   Gupta, Achla ^a   Devi, Lakshmi A ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

GPCR oligomer; Heterodimerization; Morphine tolerance; Opioid receptors; Subtractive immunization

Indexed keywords

ALCOHOL; CANNABINOID RECEPTOR; G PROTEIN COUPLED RECEPTOR; MONOCLONAL ANTIBODY; MORPHINE; OPIATE RECEPTOR;

ANALGESIA; ARTICLE; CELL MIGRATION; CLONE; CYTOLYSIS; DISEASE CONTROL; DRUG RECEPTOR BINDING; DRUG TOLERANCE; ENZYME LINKED IMMUNOSORBENT ASSAY; ETHANOL INDUCED LIVER FIBROSIS; HUMAN; HYBRIDOMA; IMMUNIZATION; IMMUNOFLUORESCENCE; LIVER FIBROSIS; NONHUMAN; PARKINSON DISEASE; PREECLAMPSIA; PRIORITY JOURNAL; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; SUPERNATANT; WESTERN BLOTTING;

EID: 84873041055     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/B978-0-12-391862-8.00012-0     Document Type: Chapter

References (48)

1. S. AbdAlla, A. Abdel-Baset, H. Lother, A. el Massiery, and U. Quitterer Mesangial AT1/B2 receptor heterodimers contribute to angiotensin II hyperresponsiveness in experimental hypertension Journal of Molecular Neuroscience 26 2005 185 192
2. N.A. Balenga, C.M. Henstridge, J. Kargl, and M. Waldhoer Pharmacology, signaling and physiological relevance of the G protein-coupled receptor 55 Advances in Pharmacology 62 2011 251 277
3. K.A. Berg, M.P. Rowan, A. Gupta, T.A. Sanchez, M. Silva, and I. Gomes Allosteric interactions between delta and kappa opioid receptors in peripheral sensory neurons Molecular Pharmacology 81 2012 264 272
4. R.G. Bhushan, S.K. Sharma, Z. Xie, D.J. Daniels, and P.S. Portoghese A bivalent ligand (KDN-21) reveals spinal delta and kappa opioid receptors are organized as heterodimers that give rise to delta(1) and kappa(2) phenotypes. Selective targeting of delta-kappa heterodimers Journal of Medicinal Chemistry 47 2004 2969 2972
5. I. Bushlin, R. Rozenfeld, and L.A. Devi Cannabinoid-opioid interactions during neuropathic pain and analgesia Current Opinion in Pharmacology 10 2010 80 86
6. C. Chen, J. Li, G. Bot, I. Szabo, T.J. Rogers, and L.Y. Liu-Chen Heterodimerization and cross-desensitization between the mu-opioid receptor and the chemokine CCR5 receptor European Journal of Pharmacology 483 2004 175 186
7. D.L. Cichewicz Synergistic interactions between cannabinoid and opioid analgesics Life Sciences 74 2004 1317 1324
8. S. Cvejic, and L.A. Devi Dimerization of the delta opioid receptor: Implication for a role in receptor internalization Journal of Biological Chemistry 272 1997 26959 26964
9. F.M. Decaillot, R. Rozenfeld, A. Gupta, and L.A. Devi Cell surface targeting of mu-delta opioid receptor heterodimers by RTP4 Proceedings of the National Academy of Sciences of the United States of America 105 2008 16045 16050
10. N. Dietis, D.J. Rowbotham, and D.G. Lambert Opioid receptor subtypes: Fact or artifact? British Journal of Anaesthesia 107 2011 8 18
11. V. Di Marzo, F. Piscitelli, and R. Mechoulam Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes Handbook of Experimental Pharmacology 203 2011 75 104
12. M. Dziedzicka-Wasylewska, A. Faron-Gorecka, A. Gorecki, and M. Kusemider Mechanism of action of clozapine in the context of dopamine D1-D2 receptor hetero-dimerization - A working hypothesis Pharmacological Reports 60 2008 581 587
13. P.L. Ey, S.J. Prowse, and C.R. Jenkin Isolation of pure Igg1, Igg2a and Igg2b immunoglobulins from mouse serum using protein A-sepharose Immunochemistry 15 1978 429 436
14. A. Faron-Gorecka, A. Gorecki, M. Kusmider, Z. Wasylewski, and M. Dziedzicka-Wasylewska The role of D1-D2 receptor hetero-dimerization in the mechanism of action of clozapine European Neuropsychopharmacology 18 2008 682 691
15. K. Fuxe, S. Ferre, M. Canals, M. Torvinen, A. Terasmaa, and D. Marcellino Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function Journal of Molecular Neuroscience 26 2005 209 220
16. I. Gomes, A. Gupta, J. Filipovska, H.H. Szeto, J.E. Pintar, and L.A. Devi A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia Proceedings of the National Academy of Sciences of the United States of America 101 2004 5135 5139
17. I. Gomes, A.P. Ijzerman, K. Ye, E.L. Maillet, and L.A. Devi G protein-coupled receptor heteromerization: A role in allosteric modulation of ligand binding Molecular Pharmacology 79 2011 1044 1052
18. I. Gomes, B.A. Jordan, A. Gupta, N. Trapaidze, V. Nagy, and L.A. Devi Heterodimerization of mu and delta opioid receptors: A role in opiate synergy Journal of Neuroscience 20 2000 RC110
19. L. Gonzalez-Hernandez Mde, D. Godinez-Hernandez, R.A. Bobadilla-Lugo, and P. Lopez-Sanchez Angiotensin-II type 1 receptor (AT1R) and alpha-1D adrenoceptor form a heterodimer during pregnancy-induced hypertension Autonomic & Autacoid Pharmacology 30 2010 167 172
20. A. Gupta, J. Mulder, I. Gomes, R. Rozenfeld, I. Bushlin, and E. Ong Increased abundance of opioid receptor heteromers after chronic morphine administration Science Signal 3 2010 ra54
21. S.Q. He, Z.N. Zhang, J.S. Guan, H.R. Liu, B. Zhao, and H.B. Wang Facilitation of mu-opioid receptor activity by preventing delta-opioid receptor-mediated codegradation Neuron 69 2011 120 131
22. D. Hereld, and T. Jin Slamming the DOR on chemokine receptor signaling: Heterodimerization silences ligand-occupied CXCR4 and delta-opioid receptors European Journal of Immunology 38 2008 334 337
23. N.J. Hoogenraad, and C.J. Wraight The effect of pristane on ascites tumor formation and monoclonal antibody production Methods in Enzymology 121 1986 375 381
24. A.C. Howlett, F. Barth, T.I. Bonner, G. Cabral, P. Casellas, and W.A. Devane International Union of Pharmacology. XXVII. Classification of cannabinoid receptors Pharmacological Reviews 54 2002 161 202
25. B.A. Jordan, and L.A. Devi G-protein-coupled receptor heterodimerization modulates receptor function Nature 399 1999 697 700
26. B.A. Jordan, I. Gomes, C. Rios, J. Filipovska, and L.A. Devi Functional interactions between mu opioid and alpha 2A-adrenergic receptors Molecular Pharmacology 64 2003 1317 1324
27. B.A. Jordan, N. Trapaidze, I. Gomes, R. Nivarthi, and L.A. Devi Oligomerization of opioid receptors with beta 2-adrenergic receptors: A role in trafficking and mitogen-activated protein kinase activation Proceedings of the National Academy of Sciences of the United States of America 98 2001 343 348
28. N. Kabli, N. Martin, T. Fan, T. Nguyen, A. Hasbi, and G. Balboni Agonists at the delta-opioid receptor modify the binding of micro-receptor agonists to the micro-delta receptor hetero-oligomer British Journal of Pharmacology 161 2010 1122 1136
29. G. Kohler, and C. Milstein Continuous cultures of fused cells secreting antibody of predefined specificity Nature 256 1975 495 497
30. B.A. Levac, B.F. O'Dowd, and S.R. George Oligomerization of opioid receptors: Generation of novel signaling units Current Opinion in Pharmacology 2 2002 76 81
31. R. Maggio, and M.J. Millan Dopamine D2-D3 receptor heteromers: Pharmacological properties and therapeutic significance Current Opinion in Pharmacology 10 2010 100 107
32. R. Maldonado, O. Valverde, and F. Berrendero Involvement of the endocannabinoid system in drug addiction Trends in Neurosciences 29 2006 225 232
33. J. Manzanares, J. Corchero, J. Romero, J.J. Fernandez-Ruiz, J.A. Ramos, and J.A. Fuentes Pharmacological and biochemical interactions between opioids and cannabinoids Trends in Pharmacological Sciences 20 1999 287 294
34. L. Pei, S. Li, M. Wang, M. Diwan, H. Anisman, and P.J. Fletcher Uncoupling the dopamine D1-D2 receptor complex exerts antidepressant-like effects Nature Medicine 16 2010 1393 1395
35. O.M. Pello, L. Martinez-Munoz, V. Parrillas, A. Serrano, J.M. Rodriguez-Frade, and M.J. Toro Ligand stabilization of CXCR4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation European Journal of Immunology 38 2008 537 549
36. M.L. Perreault, B.F. O'Dowd, and S.R. George Dopamine receptor homooligomers and heterooligomers in schizophrenia CNS Neuroscience and Therapeutics 17 2011 52 57
37. M. Pfeiffer, S. Kirscht, R. Stumm, T. Koch, D. Wu, and M. Laugsch Heterodimerization of substance P and mu-opioid receptors regulates receptor trafficking and resensitization Journal of Biological Chemistry 278 2003 51630 51637
38. M. Pfeiffer, T. Koch, H. Schroder, M. Laugsch, V. Hollt, and S. Schulz Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization Journal of Biological Chemistry 277 2002 19762 19772
39. C. Rios, I. Gomes, and L.A. Devi Interactions between delta opioid receptors and alpha-adrenoceptors Clinical and Experimental Pharmacology and Physiology 31 2004 833 836
40. C. Rios, I. Gomes, and L.A. Devi mu opioid and CB1 cannabinoid receptor interactions: Reciprocal inhibition of receptor signaling and neuritogenesis British Journal of Pharmacology 148 2006 387 395
41. R. Rozenfeld, I. Bushlin, I. Gomes, N. Tzavaras, A. Gupta, and S. Neves Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons PLoS One 7 2012 e29239
42. R. Rozenfeld, and L.A. Devi Receptor heterodimerization leads to a switch in signaling: Beta-arrestin2-mediated ERK activation by mu-delta opioid receptor heterodimers The FASEB Journal 21 2007 2455 2465
43. R. Rozenfeld, A. Gupta, K. Gagnidze, M.P. Lim, I. Gomes, and D. Lee-Ramos AT1R-CBR heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II EMBO Journal 30 2011 2350 2363
44. R.A. Salata, I.J. Malhotra, R.K. Hampson, D.F. Ayers, C.S. Tomich, and F.M. Rottman Application of an immune-tolerizing procedure to generate monoclonal antibodies specific to an alternate protein isoform of bovine growth hormone Analytical Biochemistry 207 1992 142 149
45. M. Shulman, C.D. Wilde, and G. Kohler A better cell line for making hybridomas secreting specific antibodies Nature 276 1978 269 270
46. H.M. Sleister, and A.G. Rao Strategies to generate antibodies capable of distinguishing between proteins with > 90% amino acid identity Journal of Immunological Methods 252 2001 121 129
47. H.M. Sleister, and A.G. Rao Subtractive immunization: A tool for the generation of discriminatory antibodies to proteins of similar sequence Journal of Immunological Methods 261 2002 213 220
48. D. Vigano, T. Rubino, and D. Parolaro Molecular and cellular basis of cannabinoid and opioid interactions Pharmacology, Biochemistry, and Behavior 81 2005 360 368