-
1
-
-
0037468688
-
Opioids and chronic neuropathic pain
-
Foley K.M. Opioids and chronic neuropathic pain. N Engl J Med 348 (2003) 1279-1281
-
(2003)
N Engl J Med
, vol.348
, pp. 1279-1281
-
-
Foley, K.M.1
-
2
-
-
20644431597
-
Efficacy and safety of opioid agonists in the treatment of neuropathic pain of nonmalignant origin: systematic review and meta-analysis of randomized controlled trials
-
Eisenberg E., McNicol E.D., and Carr D.B. Efficacy and safety of opioid agonists in the treatment of neuropathic pain of nonmalignant origin: systematic review and meta-analysis of randomized controlled trials. JAMA 293 (2005) 3043-3052
-
(2005)
JAMA
, vol.293
, pp. 3043-3052
-
-
Eisenberg, E.1
McNicol, E.D.2
Carr, D.B.3
-
3
-
-
33947709329
-
Chronic neuropathic pain: mechanisms, drug targets and measurement
-
Finnerup N.B., Sindrup S.H., and Jensen T.S. Chronic neuropathic pain: mechanisms, drug targets and measurement. Fundam Clin Pharmacol 21 (2007) 129-136
-
(2007)
Fundam Clin Pharmacol
, vol.21
, pp. 129-136
-
-
Finnerup, N.B.1
Sindrup, S.H.2
Jensen, T.S.3
-
4
-
-
28744459284
-
Chronic pain in individuals with spinal cord injury: a survey and longitudinal study
-
Jensen M.P., Hoffman A.J., and Cardenas D.D. Chronic pain in individuals with spinal cord injury: a survey and longitudinal study. Spinal Cord 43 (2005) 704-712
-
(2005)
Spinal Cord
, vol.43
, pp. 704-712
-
-
Jensen, M.P.1
Hoffman, A.J.2
Cardenas, D.D.3
-
5
-
-
67651028391
-
Interaction of the cannabinoid and opioid systems in the modulation of nociception
-
Welch S.P. Interaction of the cannabinoid and opioid systems in the modulation of nociception. Int Rev Psychiatry 21 (2009) 143-151
-
(2009)
Int Rev Psychiatry
, vol.21
, pp. 143-151
-
-
Welch, S.P.1
-
6
-
-
0029417155
-
Recent advances in molecular recognition and signal transduction of active peptides: receptors for opioid peptides
-
Kieffer B.L. Recent advances in molecular recognition and signal transduction of active peptides: receptors for opioid peptides. Cell Mol Neurobiol 15 (1995) 615-635
-
(1995)
Cell Mol Neurobiol
, vol.15
, pp. 615-635
-
-
Kieffer, B.L.1
-
7
-
-
18444376760
-
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
-
Howlett A.C., Barth F., Bonner T.I., Cabral G., Casellas P., Devane W.A., Felder C.C., Herkenham M., Mackie K., Martin B.R., et al. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev 54 (2002) 161-202
-
(2002)
Pharmacol Rev
, vol.54
, pp. 161-202
-
-
Howlett, A.C.1
Barth, F.2
Bonner, T.I.3
Cabral, G.4
Casellas, P.5
Devane, W.A.6
Felder, C.C.7
Herkenham, M.8
Mackie, K.9
Martin, B.R.10
-
8
-
-
0343718836
-
Pharmacological and biochemical interactions between opioids and cannabinoids
-
Manzanares J., Corchero J., Romero J., Fernandez-Ruiz J.J., Ramos J.A., and Fuentes J.A. Pharmacological and biochemical interactions between opioids and cannabinoids. Trends Pharmacol Sci 20 (1999) 287-294
-
(1999)
Trends Pharmacol Sci
, vol.20
, pp. 287-294
-
-
Manzanares, J.1
Corchero, J.2
Romero, J.3
Fernandez-Ruiz, J.J.4
Ramos, J.A.5
Fuentes, J.A.6
-
9
-
-
0346099153
-
Synergistic interactions between cannabinoid and opioid analgesics
-
Cichewicz D.L. Synergistic interactions between cannabinoid and opioid analgesics. Life Sci 74 (2004) 1317-1324
-
(2004)
Life Sci
, vol.74
, pp. 1317-1324
-
-
Cichewicz, D.L.1
-
10
-
-
0033586332
-
Pre- and postsynaptic distribution of cannabinoid and mu opioid receptors in rat spinal cord
-
Hohmann A.G., Briley E.M., and Herkenham M. Pre- and postsynaptic distribution of cannabinoid and mu opioid receptors in rat spinal cord. Brain Res 822 (1999) 17-25
-
(1999)
Brain Res
, vol.822
, pp. 17-25
-
-
Hohmann, A.G.1
Briley, E.M.2
Herkenham, M.3
-
11
-
-
0035807990
-
CB1-cannabinoid and mu-opioid receptor co-localization on postsynaptic target in the rat dorsal horn
-
1R and MOR on individual neurons within the dorsal horn the spinal cord, by immunoelectron microscopy.
-
1R and MOR on individual neurons within the dorsal horn the spinal cord, by immunoelectron microscopy.
-
(2001)
Neuroreport
, vol.12
, pp. 3689-3692
-
-
Salio, C.1
Fischer, J.2
Franzoni, M.F.3
Mackie, K.4
Kaneko, T.5
Conrath, M.6
-
12
-
-
20444399468
-
Molecular and cellular basis of cannabinoid and opioid interactions
-
Vigano D., Rubino T., and Parolaro D. Molecular and cellular basis of cannabinoid and opioid interactions. Pharmacol Biochem Behav 81 (2005) 360-368
-
(2005)
Pharmacol Biochem Behav
, vol.81
, pp. 360-368
-
-
Vigano, D.1
Rubino, T.2
Parolaro, D.3
-
13
-
-
0036470141
-
Motivational effects of cannabinoids are mediated by mu-opioid and kappa-opioid receptors
-
Ghozland S., Matthes H.W., Simonin F., Filliol D., Kieffer B.L., and Maldonado R. Motivational effects of cannabinoids are mediated by mu-opioid and kappa-opioid receptors. J Neurosci 22 (2002) 1146-1154
-
(2002)
J Neurosci
, vol.22
, pp. 1146-1154
-
-
Ghozland, S.1
Matthes, H.W.2
Simonin, F.3
Filliol, D.4
Kieffer, B.L.5
Maldonado, R.6
-
14
-
-
0037232392
-
Cannabinoid withdrawal syndrome is reduced in double mu and delta opioid receptor knockout mice
-
Castane A., Robledo P., Matifas A., Kieffer B.L., and Maldonado R. Cannabinoid withdrawal syndrome is reduced in double mu and delta opioid receptor knockout mice. Eur J Neurosci 17 (2003) 155-159
-
(2003)
Eur J Neurosci
, vol.17
, pp. 155-159
-
-
Castane, A.1
Robledo, P.2
Matifas, A.3
Kieffer, B.L.4
Maldonado, R.5
-
15
-
-
0034095022
-
Reduction of stress-induced analgesia but not of exogenous opioid effects in mice lacking CB1 receptors
-
Valverde O., Ledent C., Beslot F., Parmentier M., and Roques B.P. Reduction of stress-induced analgesia but not of exogenous opioid effects in mice lacking CB1 receptors. Eur J Neurosci 12 (2000) 533-539
-
(2000)
Eur J Neurosci
, vol.12
, pp. 533-539
-
-
Valverde, O.1
Ledent, C.2
Beslot, F.3
Parmentier, M.4
Roques, B.P.5
-
16
-
-
0033955624
-
Dynorphin B and spinal analgesia: induction of antinociception by the cannabinoids CP55,940, Delta(9)-THC and anandamide
-
Houser S.J., Eads M., Embrey J.P., and Welch S.P. Dynorphin B and spinal analgesia: induction of antinociception by the cannabinoids CP55,940, Delta(9)-THC and anandamide. Brain Res 857 (2000) 337-342
-
(2000)
Brain Res
, vol.857
, pp. 337-342
-
-
Houser, S.J.1
Eads, M.2
Embrey, J.P.3
Welch, S.P.4
-
17
-
-
0345540636
-
Cannabinoid modulation of dynorphin A: correlation to cannabinoid-induced antinociception
-
Mason Jr. D.J., Lowe J., and Welch S.P. Cannabinoid modulation of dynorphin A: correlation to cannabinoid-induced antinociception. Eur J Pharmacol 378 (1999) 237-248
-
(1999)
Eur J Pharmacol
, vol.378
, pp. 237-248
-
-
Mason Jr., D.J.1
Lowe, J.2
Welch, S.P.3
-
18
-
-
8244238393
-
Involvement of dynorphin B in the antinociceptive effects of the cannabinoid CP55,940 in the spinal cord
-
Pugh Jr. G., Mason Jr. D.J., Combs V., and Welch S.P. Involvement of dynorphin B in the antinociceptive effects of the cannabinoid CP55,940 in the spinal cord. J Pharmacol Exp Ther 281 (1997) 730-737
-
(1997)
J Pharmacol Exp Ther
, vol.281
, pp. 730-737
-
-
Pugh Jr., G.1
Mason Jr., D.J.2
Combs, V.3
Welch, S.P.4
-
19
-
-
0028261433
-
Interactions between delta 9-tetrahydrocannabinol and kappa opioids in mice
-
Smith P.B., Welch S.P., and Martin B.R. Interactions between delta 9-tetrahydrocannabinol and kappa opioids in mice. J Pharmacol Exp Ther 268 (1994) 1381-1387
-
(1994)
J Pharmacol Exp Ther
, vol.268
, pp. 1381-1387
-
-
Smith, P.B.1
Welch, S.P.2
Martin, B.R.3
-
20
-
-
0032004188
-
Inhibition of opioid-degrading enzymes potentiates delta9-tetrahydrocannabinol-induced antinociception in mice
-
Reche I., Ruiz-Gayo M., and Fuentes J.A. Inhibition of opioid-degrading enzymes potentiates delta9-tetrahydrocannabinol-induced antinociception in mice. Neuropharmacology 37 (1998) 215-222
-
(1998)
Neuropharmacology
, vol.37
, pp. 215-222
-
-
Reche, I.1
Ruiz-Gayo, M.2
Fuentes, J.A.3
-
21
-
-
0030871674
-
delta-9-Tetrahydrocannabinol increases prodynorphin and proenkephalin gene expression in the spinal cord of the rat
-
PL39-43
-
Corchero J., Avila M.A., Fuentes J.A., and Manzanares J. delta-9-Tetrahydrocannabinol increases prodynorphin and proenkephalin gene expression in the spinal cord of the rat. Life Sci 61 (1997) PL39-43
-
(1997)
Life Sci
, vol.61
-
-
Corchero, J.1
Avila, M.A.2
Fuentes, J.A.3
Manzanares, J.4
-
22
-
-
0030901502
-
delta 9-Tetrahydrocannabinol increases proopiomelanocortin gene expression in the arcuate nucleus of the rat hypothalamus
-
Corchero J., Fuentes J.A., and Manzanares J. delta 9-Tetrahydrocannabinol increases proopiomelanocortin gene expression in the arcuate nucleus of the rat hypothalamus. Eur J Pharmacol 323 (1997) 193-195
-
(1997)
Eur J Pharmacol
, vol.323
, pp. 193-195
-
-
Corchero, J.1
Fuentes, J.A.2
Manzanares, J.3
-
23
-
-
0032579759
-
Chronic administration of cannabinoids regulates proenkephalin mRNA levels in selected regions of the rat brain
-
Manzanares J., Corchero J., Romero J., Fernandez-Ruiz J.J., Ramos J.A., and Fuentes J.A. Chronic administration of cannabinoids regulates proenkephalin mRNA levels in selected regions of the rat brain. Brain Res Mol Brain Res 55 (1998) 126-132
-
(1998)
Brain Res Mol Brain Res
, vol.55
, pp. 126-132
-
-
Manzanares, J.1
Corchero, J.2
Romero, J.3
Fernandez-Ruiz, J.J.4
Ramos, J.A.5
Fuentes, J.A.6
-
24
-
-
46449117148
-
The mu-opioid receptor agonist morphine, but not agonists at delta- or kappa-opioid receptors, induces peripheral antinociception mediated by cannabinoid receptors
-
1R with the selective antagonist AM251 abolishes the antinociceptive effects of morphine in a peripheral inflammatory pain model.
-
1R with the selective antagonist AM251 abolishes the antinociceptive effects of morphine in a peripheral inflammatory pain model.
-
(2008)
Br J Pharmacol
, vol.154
, pp. 1143-1149
-
-
da Fonseca Pacheco, D.1
Klein, A.2
de Castro Perez, A.3
da Fonseca Pacheco, C.M.4
de Francischi, J.N.5
Duarte, I.D.6
-
25
-
-
69249232082
-
Central antinociception induced by micro-opioid receptor agonist morphine, but not delta- or kappa-, is mediated by cannabinoid CB receptor
-
da Fonseca Pacheco D., Klein A., Perez A.C., da Fonseca Pacheco C.M., de Francischi J.N., Lopes Reis G.M., and Duarte I.D. Central antinociception induced by micro-opioid receptor agonist morphine, but not delta- or kappa-, is mediated by cannabinoid CB receptor. Br J Pharmacol 158 (2009) 225-231
-
(2009)
Br J Pharmacol
, vol.158
, pp. 225-231
-
-
da Fonseca Pacheco, D.1
Klein, A.2
Perez, A.C.3
da Fonseca Pacheco, C.M.4
de Francischi, J.N.5
Lopes Reis, G.M.6
Duarte, I.D.7
-
26
-
-
33845799619
-
Analgesic effects of fatty acid amide hydrolase inhibition in a rat model of neuropathic pain
-
Use of FAAH inhibitors to increase endocannabinoid levels in the spinal cord attenuates mechanical pain in an animal experiencing neuropathic pain. Interestingly, the authors demonstrate the role of opioid receptors (and endogenous opioid peptides by extension) in the antinociceptive effects of FAAH inhibitors as these effects can be blocked by naloxone.
-
Jhaveri M.D., Richardson D., Kendall D.A., Barrett D.A., and Chapman V. Analgesic effects of fatty acid amide hydrolase inhibition in a rat model of neuropathic pain. J Neurosci 26 (2006) 13318-13327. Use of FAAH inhibitors to increase endocannabinoid levels in the spinal cord attenuates mechanical pain in an animal experiencing neuropathic pain. Interestingly, the authors demonstrate the role of opioid receptors (and endogenous opioid peptides by extension) in the antinociceptive effects of FAAH inhibitors as these effects can be blocked by naloxone.
-
(2006)
J Neurosci
, vol.26
, pp. 13318-13327
-
-
Jhaveri, M.D.1
Richardson, D.2
Kendall, D.A.3
Barrett, D.A.4
Chapman, V.5
-
27
-
-
65549121665
-
Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation
-
Schlosburg J.E., Kinsey S.G., and Lichtman A.H. Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation. AAPS J 11 (2009) 39-44
-
(2009)
AAPS J
, vol.11
, pp. 39-44
-
-
Schlosburg, J.E.1
Kinsey, S.G.2
Lichtman, A.H.3
-
28
-
-
20044368975
-
CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids
-
2R can lead to beta-endorphin release from keratinocytes. This supports a role for endogenous opioid peptide release in the antinociceptive actions of cannabinoid receptor agonists.
-
2R can lead to beta-endorphin release from keratinocytes. This supports a role for endogenous opioid peptide release in the antinociceptive actions of cannabinoid receptor agonists.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3093-3098
-
-
Ibrahim, M.M.1
Porreca, F.2
Lai, J.3
Albrecht, P.J.4
Rice, F.L.5
Khodorova, A.6
Davar, G.7
Makriyannis, A.8
Vanderah, T.W.9
Mata, H.P.10
-
29
-
-
0028278083
-
Evidence for a bidirectional cross-tolerance between morphine and delta 9-tetrahydrocannabinol in mice
-
Thorat S.N., and Bhargava H.N. Evidence for a bidirectional cross-tolerance between morphine and delta 9-tetrahydrocannabinol in mice. Eur J Pharmacol 260 (1994) 5-13
-
(1994)
Eur J Pharmacol
, vol.260
, pp. 5-13
-
-
Thorat, S.N.1
Bhargava, H.N.2
-
30
-
-
0030779485
-
Modulation of rat brain cannabinoid receptors after chronic morphine treatment
-
Rubino T., Tizzoni L., Vigano D., Massi P., and Parolaro D. Modulation of rat brain cannabinoid receptors after chronic morphine treatment. Neuroreport 8 (1997) 3219-3223
-
(1997)
Neuroreport
, vol.8
, pp. 3219-3223
-
-
Rubino, T.1
Tizzoni, L.2
Vigano, D.3
Massi, P.4
Parolaro, D.5
-
31
-
-
26844459148
-
Molecular mechanisms involved in the asymmetric interaction between cannabinoid and opioid systems
-
Vigano D., Rubino T., Vaccani A., Bianchessi S., Marmorato P., Castiglioni C., and Parolaro D. Molecular mechanisms involved in the asymmetric interaction between cannabinoid and opioid systems. Psychopharmacology (Berl) 182 (2005) 527-536
-
(2005)
Psychopharmacology (Berl)
, vol.182
, pp. 527-536
-
-
Vigano, D.1
Rubino, T.2
Vaccani, A.3
Bianchessi, S.4
Marmorato, P.5
Castiglioni, C.6
Parolaro, D.7
-
32
-
-
0342979873
-
The CB1 cannabinoid receptor can sequester G-proteins, making them unavailable to couple to other receptors
-
Vasquez C., and Lewis D.L. The CB1 cannabinoid receptor can sequester G-proteins, making them unavailable to couple to other receptors. J Neurosci 19 (1999) 9271-9280
-
(1999)
J Neurosci
, vol.19
, pp. 9271-9280
-
-
Vasquez, C.1
Lewis, D.L.2
-
34
-
-
0242720430
-
Participation of the opioid system in cannabinoid-induced antinociception and emotional-like responses
-
Maldonado R., and Valverde O. Participation of the opioid system in cannabinoid-induced antinociception and emotional-like responses. Eur Neuropsychopharmacol 13 (2003) 401-410
-
(2003)
Eur Neuropsychopharmacol
, vol.13
, pp. 401-410
-
-
Maldonado, R.1
Valverde, O.2
-
35
-
-
0034671190
-
Cannabinoid withdrawal syndrome is reduced in pre-proenkephalin knock-out mice
-
Valverde O., Maldonado R., Valjent E., Zimmer A.M., and Zimmer A. Cannabinoid withdrawal syndrome is reduced in pre-proenkephalin knock-out mice. J Neurosci 20 (2000) 9284-9289
-
(2000)
J Neurosci
, vol.20
, pp. 9284-9289
-
-
Valverde, O.1
Maldonado, R.2
Valjent, E.3
Zimmer, A.M.4
Zimmer, A.5
-
36
-
-
17144401168
-
Synergistic and additive interactions of the cannabinoid agonist CP55,940 with mu opioid receptor and alpha2-adrenoceptor agonists in acute pain models in mice
-
Combinations of opioid and cannabinoid agonists can induce synergistic analgesia in an animal experiencing acute pain. The extension of these studies to models of chronic pain is essential for evaluating the potential of combining therapies for this disease state.
-
Tham S.M., Angus J.A., Tudor E.M., and Wright C.E. Synergistic and additive interactions of the cannabinoid agonist CP55,940 with mu opioid receptor and alpha2-adrenoceptor agonists in acute pain models in mice. Br J Pharmacol 144 (2005) 875-884. Combinations of opioid and cannabinoid agonists can induce synergistic analgesia in an animal experiencing acute pain. The extension of these studies to models of chronic pain is essential for evaluating the potential of combining therapies for this disease state.
-
(2005)
Br J Pharmacol
, vol.144
, pp. 875-884
-
-
Tham, S.M.1
Angus, J.A.2
Tudor, E.M.3
Wright, C.E.4
-
37
-
-
0035087086
-
Changes in opioid and cannabinoid receptor protein following short-term combination treatment with delta(9)-tetrahydrocannabinol and morphine
-
Cichewicz D.L., Haller V.L., and Welch S.P. Changes in opioid and cannabinoid receptor protein following short-term combination treatment with delta(9)-tetrahydrocannabinol and morphine. J Pharmacol Exp Ther 297 (2001) 121-127
-
(2001)
J Pharmacol Exp Ther
, vol.297
, pp. 121-127
-
-
Cichewicz, D.L.1
Haller, V.L.2
Welch, S.P.3
-
38
-
-
1642299444
-
Loss of peripheral morphine analgesia contributes to the reduced effectiveness of systemic morphine in neuropathic pain
-
Rashid M.H., Inoue M., Toda K., and Ueda H. Loss of peripheral morphine analgesia contributes to the reduced effectiveness of systemic morphine in neuropathic pain. J Pharmacol Exp Ther 309 (2004) 380-387
-
(2004)
J Pharmacol Exp Ther
, vol.309
, pp. 380-387
-
-
Rashid, M.H.1
Inoue, M.2
Toda, K.3
Ueda, H.4
-
39
-
-
0141738711
-
Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behaviors in rats
-
Lim G., Sung B., Ji R.R., and Mao J. Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behaviors in rats. Pain 105 (2003) 275-283
-
(2003)
Pain
, vol.105
, pp. 275-283
-
-
Lim, G.1
Sung, B.2
Ji, R.R.3
Mao, J.4
-
40
-
-
33751244807
-
Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain
-
Mitrirattanakul S., Ramakul N., Guerrero A.V., Matsuka Y., Ono T., Iwase H., Mackie K., Faull K.F., and Spigelman I. Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain. Pain 126 (2006) 102-114
-
(2006)
Pain
, vol.126
, pp. 102-114
-
-
Mitrirattanakul, S.1
Ramakul, N.2
Guerrero, A.V.3
Matsuka, Y.4
Ono, T.5
Iwase, H.6
Mackie, K.7
Faull, K.F.8
Spigelman, I.9
-
41
-
-
18044379749
-
Behavioral, pharmacological and molecular characterization of the saphenous nerve partial ligation: a new model of neuropathic pain
-
Walczak J.S., Pichette V., Leblond F., Desbiens K., and Beaulieu P. Behavioral, pharmacological and molecular characterization of the saphenous nerve partial ligation: a new model of neuropathic pain. Neuroscience 132 (2005) 1093-1102
-
(2005)
Neuroscience
, vol.132
, pp. 1093-1102
-
-
Walczak, J.S.1
Pichette, V.2
Leblond, F.3
Desbiens, K.4
Beaulieu, P.5
-
42
-
-
0035831179
-
Cannabinoid CB(1) receptor upregulation in a rat model of chronic neuropathic pain
-
Siegling A., Hofmann H.A., Denzer D., Mauler F., and De Vry J. Cannabinoid CB(1) receptor upregulation in a rat model of chronic neuropathic pain. Eur J Pharmacol 415 (2001) R5-7
-
(2001)
Eur J Pharmacol
, vol.415
-
-
Siegling, A.1
Hofmann, H.A.2
Denzer, D.3
Mauler, F.4
De Vry, J.5
-
43
-
-
58749092289
-
Local peripheral opioid effects and expression of opioid genes in the spinal cord and dorsal root ganglia in neuropathic and inflammatory pain
-
Obara I., Parkitna J.R., Korostynski M., Makuch W., Kaminska D., Przewlocka B., and Przewlocki R. Local peripheral opioid effects and expression of opioid genes in the spinal cord and dorsal root ganglia in neuropathic and inflammatory pain. Pain 141 (2009) 283-291
-
(2009)
Pain
, vol.141
, pp. 283-291
-
-
Obara, I.1
Parkitna, J.R.2
Korostynski, M.3
Makuch, W.4
Kaminska, D.5
Przewlocka, B.6
Przewlocki, R.7
-
44
-
-
0030921750
-
Down-regulation of mu-opioid receptors in rat and monkey dorsal root ganglion neurons and spinal cord after peripheral axotomy
-
Zhang X., Bao L., Shi T.J., Ju G., Elde R., and Hokfelt T. Down-regulation of mu-opioid receptors in rat and monkey dorsal root ganglion neurons and spinal cord after peripheral axotomy. Neuroscience 82 (1998) 223-240
-
(1998)
Neuroscience
, vol.82
, pp. 223-240
-
-
Zhang, X.1
Bao, L.2
Shi, T.J.3
Ju, G.4
Elde, R.5
Hokfelt, T.6
-
45
-
-
6344291677
-
Rapid upregulation of mu opioid receptor mRNA in dorsal root ganglia in response to peripheral inflammation depends on neuronal conduction
-
Puehler W., Zollner C., Brack A., Shaqura M.A., Krause H., Schafer M., and Stein C. Rapid upregulation of mu opioid receptor mRNA in dorsal root ganglia in response to peripheral inflammation depends on neuronal conduction. Neuroscience 129 (2004) 473-479
-
(2004)
Neuroscience
, vol.129
, pp. 473-479
-
-
Puehler, W.1
Zollner, C.2
Brack, A.3
Shaqura, M.A.4
Krause, H.5
Schafer, M.6
Stein, C.7
-
46
-
-
0026795683
-
Regulation of opioid binding sites in the superficial dorsal horn of the rat spinal cord following loose ligation of the sciatic nerve: comparison with sciatic nerve section and lumbar dorsal rhizotomy
-
Besse D., Lombard M.C., Perrot S., and Besson J.M. Regulation of opioid binding sites in the superficial dorsal horn of the rat spinal cord following loose ligation of the sciatic nerve: comparison with sciatic nerve section and lumbar dorsal rhizotomy. Neuroscience 50 (1992) 921-933
-
(1992)
Neuroscience
, vol.50
, pp. 921-933
-
-
Besse, D.1
Lombard, M.C.2
Perrot, S.3
Besson, J.M.4
-
47
-
-
0037439068
-
Suppression of the morphine-induced rewarding effect and G-protein activation in the lower midbrain following nerve injury in the mouse: involvement of G-protein-coupled receptor kinase 2
-
Ozaki S., Narita M., Narita M., Iino M., Miyoshi K., and Suzuki T. Suppression of the morphine-induced rewarding effect and G-protein activation in the lower midbrain following nerve injury in the mouse: involvement of G-protein-coupled receptor kinase 2. Neuroscience 116 (2003) 89-97
-
(2003)
Neuroscience
, vol.116
, pp. 89-97
-
-
Ozaki, S.1
Narita, M.2
Narita, M.3
Iino, M.4
Miyoshi, K.5
Suzuki, T.6
-
48
-
-
30344449474
-
Expression of opioid receptors and c-fos in CB1 knockout mice exposed to neuropathic pain
-
1R knockout animals during the development of neuropathic pain. While MOR mRNA is decreased in both wild-type and CB1R knockout animals, DOR and KOR mRNA are unchanged after partial sciatic nerve lesion in both genotypes.
-
1R knockout animals during the development of neuropathic pain. While MOR mRNA is decreased in both wild-type and CB1R knockout animals, DOR and KOR mRNA are unchanged after partial sciatic nerve lesion in both genotypes.
-
(2006)
Neuropharmacology
, vol.50
, pp. 123-132
-
-
Pol, O.1
Murtra, P.2
Caracuel, L.3
Valverde, O.4
Puig, M.M.5
Maldonado, R.6
-
49
-
-
0035282798
-
Pronociceptive actions of dynorphin maintain chronic neuropathic pain
-
Wang Z., Gardell L.R., Ossipov M.H., Vanderah T.W., Brennan M.B., Hochgeschwender U., Hruby V.J., Malan Jr. T.P., Lai J., and Porreca F. Pronociceptive actions of dynorphin maintain chronic neuropathic pain. J Neurosci 21 (2001) 1779-1786
-
(2001)
J Neurosci
, vol.21
, pp. 1779-1786
-
-
Wang, Z.1
Gardell, L.R.2
Ossipov, M.H.3
Vanderah, T.W.4
Brennan, M.B.5
Hochgeschwender, U.6
Hruby, V.J.7
Malan Jr., T.P.8
Lai, J.9
Porreca, F.10
-
50
-
-
0034703593
-
Association of kappa opioid receptor mRNA upregulation in dorsal root ganglia with mechanical allodynia in mice following nerve injury
-
Sung B., Loh H.H., and Wei L. Association of kappa opioid receptor mRNA upregulation in dorsal root ganglia with mechanical allodynia in mice following nerve injury. Neurosci Lett 291 (2000) 163-166
-
(2000)
Neurosci Lett
, vol.291
, pp. 163-166
-
-
Sung, B.1
Loh, H.H.2
Wei, L.3
-
51
-
-
3042592978
-
Compartment-specific localization of cannabinoid 1 (CB1) and mu-opioid receptors in rat nucleus accumbens
-
Pickel V.M., Chan J., Kash T.L., Rodriguez J.J., and MacKie K. Compartment-specific localization of cannabinoid 1 (CB1) and mu-opioid receptors in rat nucleus accumbens. Neuroscience 127 (2004) 101-112
-
(2004)
Neuroscience
, vol.127
, pp. 101-112
-
-
Pickel, V.M.1
Chan, J.2
Kash, T.L.3
Rodriguez, J.J.4
MacKie, K.5
-
52
-
-
0035112869
-
Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus
-
Rodriguez J.J., Mackie K., and Pickel V.M. Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus. J Neurosci 21 (2001) 823-833
-
(2001)
J Neurosci
, vol.21
, pp. 823-833
-
-
Rodriguez, J.J.1
Mackie, K.2
Pickel, V.M.3
-
53
-
-
33644540495
-
Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors
-
Kathmann M., Flau K., Redmer A., Trankle C., and Schlicker E. Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors. Naunyn Schmiedebergs Arch Pharmacol 372 (2006) 354-361
-
(2006)
Naunyn Schmiedebergs Arch Pharmacol
, vol.372
, pp. 354-361
-
-
Kathmann, M.1
Flau, K.2
Redmer, A.3
Trankle, C.4
Schlicker, E.5
-
54
-
-
0023255735
-
Modulation of rat brain opioid receptors by cannabinoids
-
Vaysse P.J., Gardner E.L., and Zukin R.S. Modulation of rat brain opioid receptors by cannabinoids. J Pharmacol Exp Ther 241 (1987) 534-539
-
(1987)
J Pharmacol Exp Ther
, vol.241
, pp. 534-539
-
-
Vaysse, P.J.1
Gardner, E.L.2
Zukin, R.S.3
-
55
-
-
0032556059
-
Independence of, and interactions between, cannabinoid and opioid signal transduction pathways in N18TG2 cells
-
Shapira M., Gafni M., and Sarne Y. Independence of, and interactions between, cannabinoid and opioid signal transduction pathways in N18TG2 cells. Brain Res 806 (1998) 26-35
-
(1998)
Brain Res
, vol.806
, pp. 26-35
-
-
Shapira, M.1
Gafni, M.2
Sarne, Y.3
-
56
-
-
33745085564
-
mu opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis
-
First study to show direct, biophysical interactions between opioid and cannabinoid receptors, in cotransfected cells. The authors also find antagonistic interactions between the two receptor types in cotransfected cells and in native tissue exposed to increasing concentrations of an agonist to one receptor along with nonactivating concentrations of an agonist of the other receptor.
-
Rios C., Gomes I., and Devi L.A. mu opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis. Br J Pharmacol 148 (2006) 387-395. First study to show direct, biophysical interactions between opioid and cannabinoid receptors, in cotransfected cells. The authors also find antagonistic interactions between the two receptor types in cotransfected cells and in native tissue exposed to increasing concentrations of an agonist to one receptor along with nonactivating concentrations of an agonist of the other receptor.
-
(2006)
Br J Pharmacol
, vol.148
, pp. 387-395
-
-
Rios, C.1
Gomes, I.2
Devi, L.A.3
-
57
-
-
30044442319
-
Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series
-
Daniels D.J., Lenard N.R., Etienne C.L., Law P.Y., Roerig S.C., and Portoghese P.S. Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series. Proc Natl Acad Sci U S A 102 (2005) 19208-19213
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 19208-19213
-
-
Daniels, D.J.1
Lenard, N.R.2
Etienne, C.L.3
Law, P.Y.4
Roerig, S.C.5
Portoghese, P.S.6
-
58
-
-
30444447793
-
Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors
-
Peng X., Knapp B.I., Bidlack J.M., and Neumeyer J.L. Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors. J Med Chem 49 (2006) 256-262
-
(2006)
J Med Chem
, vol.49
, pp. 256-262
-
-
Peng, X.1
Knapp, B.I.2
Bidlack, J.M.3
Neumeyer, J.L.4
-
59
-
-
0030010349
-
Expression of mu- and kappa-, but not delta-, opioid receptor mRNAs is enhanced in the spinal dorsal horn of the arthritic rats
-
Maekawa K., Minami M., Masuda T., and Satoh M. Expression of mu- and kappa-, but not delta-, opioid receptor mRNAs is enhanced in the spinal dorsal horn of the arthritic rats. Pain 64 (1996) 365-371
-
(1996)
Pain
, vol.64
, pp. 365-371
-
-
Maekawa, K.1
Minami, M.2
Masuda, T.3
Satoh, M.4
-
60
-
-
0024268743
-
Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding
-
Iadarola M.J., Brady L.S., Draisci G., and Dubner R. Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding. Pain 35 (1988) 313-326
-
(1988)
Pain
, vol.35
, pp. 313-326
-
-
Iadarola, M.J.1
Brady, L.S.2
Draisci, G.3
Dubner, R.4
-
61
-
-
0024208582
-
Inflammation of the hind limb as a model of unilateral, localized pain: influence on multiple opioid systems in the spinal cord of the rat
-
Millan M.J., Czlonkowski A., Morris B., Stein C., Arendt R., Huber A., Hollt V., and Herz A. Inflammation of the hind limb as a model of unilateral, localized pain: influence on multiple opioid systems in the spinal cord of the rat. Pain 35 (1988) 299-312
-
(1988)
Pain
, vol.35
, pp. 299-312
-
-
Millan, M.J.1
Czlonkowski, A.2
Morris, B.3
Stein, C.4
Arendt, R.5
Huber, A.6
Hollt, V.7
Herz, A.8
-
62
-
-
0025916299
-
Bilateral and differential changes in spinal mu, delta and kappa opioid binding in rats with a painful, unilateral neuropathy
-
Stevens C.W., Kajander K.C., Bennett G.J., and Seybold V.S. Bilateral and differential changes in spinal mu, delta and kappa opioid binding in rats with a painful, unilateral neuropathy. Pain 46 (1991) 315-326
-
(1991)
Pain
, vol.46
, pp. 315-326
-
-
Stevens, C.W.1
Kajander, K.C.2
Bennett, G.J.3
Seybold, V.S.4
-
63
-
-
34249659980
-
Spinal administration of a delta opioid receptor agonist attenuates hyperalgesia and allodynia in a rat model of neuropathic pain
-
Holdridge S.V., and Cahill C.M. Spinal administration of a delta opioid receptor agonist attenuates hyperalgesia and allodynia in a rat model of neuropathic pain. Eur J Pain 11 (2007) 685-693
-
(2007)
Eur J Pain
, vol.11
, pp. 685-693
-
-
Holdridge, S.V.1
Cahill, C.M.2
-
64
-
-
2342456415
-
Effects of peripheral nerve injury on delta opioid receptor (DOR) immunoreactivity in the rat spinal cord
-
Stone L.S., Vulchanova L., Riedl M.S., Williams F.G., Wilcox G.L., and Elde R. Effects of peripheral nerve injury on delta opioid receptor (DOR) immunoreactivity in the rat spinal cord. Neurosci Lett 361 (2004) 208-211
-
(2004)
Neurosci Lett
, vol.361
, pp. 208-211
-
-
Stone, L.S.1
Vulchanova, L.2
Riedl, M.S.3
Williams, F.G.4
Wilcox, G.L.5
Elde, R.6
-
65
-
-
53349163291
-
Influences of surgical decompression on the dorsal horn after chronic constriction injury: changes in peptidergic and delta-opioid receptor (+) nerve terminals
-
Tseng T.J., Chen C.C., Hsieh Y.L., and Hsieh S.T. Influences of surgical decompression on the dorsal horn after chronic constriction injury: changes in peptidergic and delta-opioid receptor (+) nerve terminals. Neuroscience 156 (2008) 758-768
-
(2008)
Neuroscience
, vol.156
, pp. 758-768
-
-
Tseng, T.J.1
Chen, C.C.2
Hsieh, Y.L.3
Hsieh, S.T.4
-
66
-
-
0030599014
-
Effects of peripheral nerve ligation on expression of mu-opioid receptor in sensory ganglion neurons: an immunohistochemical study in dorsal root and nodose ganglion neurons of the rat
-
Li J.L., Kaneko T., and Mizuno N. Effects of peripheral nerve ligation on expression of mu-opioid receptor in sensory ganglion neurons: an immunohistochemical study in dorsal root and nodose ganglion neurons of the rat. Neurosci Lett 214 (1996) 91-94
-
(1996)
Neurosci Lett
, vol.214
, pp. 91-94
-
-
Li, J.L.1
Kaneko, T.2
Mizuno, N.3
-
67
-
-
0037371427
-
Mu opioid receptors and analgesia at the site of a peripheral nerve injury
-
Truong W., Cheng C., Xu Q.G., Li X.Q., and Zochodne D.W. Mu opioid receptors and analgesia at the site of a peripheral nerve injury. Ann Neurol 53 (2003) 366-375
-
(2003)
Ann Neurol
, vol.53
, pp. 366-375
-
-
Truong, W.1
Cheng, C.2
Xu, Q.G.3
Li, X.Q.4
Zochodne, D.W.5
-
68
-
-
0032496689
-
Spinal opioid mu receptor expression in lumbar spinal cord of rats following nerve injury
-
Porreca F., Tang Q.B., Bian D., Riedl M., Elde R., and Lai J. Spinal opioid mu receptor expression in lumbar spinal cord of rats following nerve injury. Brain Res 795 (1998) 197-203
-
(1998)
Brain Res
, vol.795
, pp. 197-203
-
-
Porreca, F.1
Tang, Q.B.2
Bian, D.3
Riedl, M.4
Elde, R.5
Lai, J.6
-
69
-
-
0033064070
-
Effects of sciatic nerve injuries on delta-opioid receptor and substance P immunoreactivities in the superficial dorsal horn of the rat
-
Robertson B., Schulte G., Elde R., and Grant G. Effects of sciatic nerve injuries on delta-opioid receptor and substance P immunoreactivities in the superficial dorsal horn of the rat. Eur J Pain 3 (1999) 115-129
-
(1999)
Eur J Pain
, vol.3
, pp. 115-129
-
-
Robertson, B.1
Schulte, G.2
Elde, R.3
Grant, G.4
-
70
-
-
0038684167
-
Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models
-
Zhang J., Hoffert C., Vu H.K., Groblewski T., Ahmad S., and O'Donnell D. Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models. Eur J Neurosci 17 (2003) 2750-2754
-
(2003)
Eur J Neurosci
, vol.17
, pp. 2750-2754
-
-
Zhang, J.1
Hoffert, C.2
Vu, H.K.3
Groblewski, T.4
Ahmad, S.5
O'Donnell, D.6
|