-
1
-
-
77955917442
-
Oxidative stress in Alzheimer disease: A possibility for prevention
-
Bonda DJ, Wang X, Perry G, Nunomura A, Tabaton M, Zhu X, Smith MA: Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology 2010, 59:290-294.
-
(2010)
Neuropharmacology
, vol.59
, pp. 290-294
-
-
Bonda, D.J.1
Wang, X.2
Perry, G.3
Nunomura, A.4
Tabaton, M.5
Zhu, X.6
Smith, M.A.7
-
3
-
-
79955051063
-
Linking lipids to Alzheimer's disease: Cholesterol and beyond
-
Di Paolo G, Kim TW: Linking lipids to Alzheimer's disease: cholesterol and beyond. Nat Rev Neurosci 2011, 12:284-296.
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 284-296
-
-
Di Paolo, G.1
Kim, T.W.2
-
4
-
-
84863337843
-
Alzheimer mechanisms and therapeutic strategies
-
Huang Y, Mucke L: Alzheimer mechanisms and therapeutic strategies. Cell 2012, 148:1204-1222.
-
(2012)
Cell
, vol.148
, pp. 1204-1222
-
-
Huang, Y.1
Mucke, L.2
-
5
-
-
84859610500
-
Alzheimer's disease and the amyloid β-protein
-
Walsh DM, Teplow DB: Alzheimer's disease and the amyloid β-protein. Prog Mol Biol Transl Sci 2012, 107:101-124.
-
(2012)
Prog Mol Biol Transl Sci
, vol.107
, pp. 101-124
-
-
Walsh, D.M.1
Teplow, D.B.2
-
6
-
-
0013897667
-
Peroxisomes (microbodies and related particles)
-
De Duve C, Baudhuin P: Peroxisomes (microbodies and related particles). Physiol Rev 1966, 46:323-357.
-
(1966)
Physiol Rev
, vol.46
, pp. 323-357
-
-
De Duve, C.1
Baudhuin, P.2
-
7
-
-
33845326985
-
Peroxisomal betaoxidation, a metabolic pathway with multiple functions
-
Poirier Y, Antonenkov VD, Glumoff T, Hiltunen JK: Peroxisomal betaoxidation, a metabolic pathway with multiple functions. Biochim Biophys Acta 2006, 1763:1413-1426.
-
(2006)
Biochim Biophys Acta
, vol.1763
, pp. 1413-1426
-
-
Poirier, Y.1
Antonenkov, V.D.2
Glumoff, T.3
Hiltunen, J.K.4
-
8
-
-
33746366462
-
Biochemistry of mammalian peroxisomes revisited
-
Wanders RJ, Waterham HR: Biochemistry of mammalian peroxisomes revisited. Annu Rev Biochem 2006, 75:295-332.
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 295-332
-
-
Wanders, R.J.1
Waterham, H.R.2
-
9
-
-
0029589279
-
Reevaluation of the pathways for the biosynthesis of polyunsaturated fatty acids
-
Sprecher H, Luthria DL, Mohammed BS, Baykousheva SP: Reevaluation of the pathways for the biosynthesis of polyunsaturated fatty acids. J Lipid Res 1995, 36:2471-2477.
-
(1995)
J Lipid Res
, vol.36
, pp. 2471-2477
-
-
Sprecher, H.1
Luthria, D.L.2
Mohammed, B.S.3
Baykousheva, S.P.4
-
10
-
-
76349092667
-
Peroxisomes, lipid metabolism and lipotoxicity
-
Wanders RJ, Ferdinandusse S, Brites P, Kemp S: Peroxisomes, lipid metabolism and lipotoxicity. Biochim Biophys Acta 2010, 1801:272-280.
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 272-280
-
-
Wanders, R.J.1
Ferdinandusse, S.2
Brites, P.3
Kemp, S.4
-
11
-
-
47249146893
-
Calcium dynamics in the peroxisomal lumen of living cells
-
Drago I, Giacomello M, Pizzo P, Pozzan T: Calcium dynamics in the peroxisomal lumen of living cells. J Biol Chem 2008, 283:14384-14390.
-
(2008)
J Biol Chem
, vol.283
, pp. 14384-14390
-
-
Drago, I.1
Giacomello, M.2
Pizzo, P.3
Pozzan, T.4
-
12
-
-
47249099921
-
Peroxisomes as novel players in cell calcium homeostasis
-
Lasorsa FM, Pinton P, Palmieri L, Scarcia P, Rottensteiner H, Rizzuto R, Palmieri F: Peroxisomes as novel players in cell calcium homeostasis. J Biol Chem 2008, 283: 15300-15308.
-
(2008)
J Biol Chem
, vol.283
, pp. 15300-15308
-
-
Lasorsa, F.M.1
Pinton, P.2
Palmieri, L.3
Scarcia, P.4
Rottensteiner, H.5
Rizzuto, R.6
Palmieri, F.7
-
13
-
-
79751472085
-
Peroxisome metabolism and cellular aging
-
Titorenko VI, Terlecky SR: Peroxisome metabolism and cellular aging. Traffic 2011, 12:252-259.
-
(2011)
Traffic
, vol.12
, pp. 252-259
-
-
Titorenko, V.I.1
Terlecky, S.R.2
-
14
-
-
84859371637
-
Peroxisome morphology in pathology
-
Ribeiro D, Castro I, Fahimi HD, Schrader M: Peroxisome morphology in pathology. Histol Histopathol 2012, 27:661-676.
-
(2012)
Histol Histopathol
, vol.27
, pp. 661-676
-
-
Ribeiro, D.1
Castro, I.2
Fahimi, H.D.3
Schrader, M.4
-
15
-
-
84859397583
-
Potential roles of peroxisomes in Alzheimer's disease and in dementia of the Alzheimer's type
-
Lizard G, Rouaud O, Demarquoy J, Cherkaoui-Malki M, Iuliano L: Potential roles of peroxisomes in Alzheimer's disease and in dementia of the Alzheimer's type. J Alzheimers Dis 2012, 29:241-254.
-
(2012)
J Alzheimers Dis
, vol.29
, pp. 241-254
-
-
Lizard, G.1
Rouaud, O.2
Demarquoy, J.3
Cherkaoui-Malki, M.4
Iuliano, L.5
-
16
-
-
80054704470
-
Peroxisomal alterations in Alzheimer's disease
-
Kou J, Kovacs GG, Höftberger R, Kulik W, Brodde A, Forss-Petter S, Hönigschnabl S, Gleiss A, Brugger B, Wanders R, Just W, Budka H, Jungwirth S, Fischer P, Berger J: Peroxisomal alterations in Alzheimer's disease. Acta Neuropathol 2011, 122:271-283.
-
(2011)
Acta Neuropathol
, vol.122
, pp. 271-283
-
-
Kou, J.1
Kovacs, G.G.2
Höftberger, R.3
Kulik, W.4
Brodde, A.5
Forss-Petter, S.6
Hönigschnabl, S.7
Gleiss, A.8
Brugger, B.9
Wanders, R.10
Just, W.11
Budka, H.12
Jungwirth, S.13
Fischer, P.14
Berger, J.15
-
17
-
-
28844467909
-
Peroxisomal proliferation protects from beta-amyloid neurodegeneration
-
Santos MJ, Quintanilla RA, Toro A, Grandy R, Dinamarca MC, Godoy JA, Inestrosa NC: Peroxisomal proliferation protects from beta-amyloid neurodegeneration. J Biol Chem 2005, 280:41057-41068.
-
(2005)
J Biol Chem
, vol.280
, pp. 41057-41068
-
-
Santos, M.J.1
Quintanilla, R.A.2
Toro, A.3
Grandy, R.4
Dinamarca, M.C.5
Godoy, J.A.6
Inestrosa, N.C.7
-
18
-
-
74949133060
-
Early biochemical and morphological modifications in the brain of a transgenic mouse model of Alzheimer's disease: A role for peroxisomes
-
Cimini A, Moreno S, D'Amelio M, Cristiano L, D'Angelo B, Falone S, Benedetti E, Carrara P, Fanelli F, Cecconi F, Amicarelli F, Cerù MP: Early biochemical and morphological modifications in the brain of a transgenic mouse model of Alzheimer's disease: a role for peroxisomes. J Alzheimer Dis 2009, 18:935-952.
-
(2009)
J Alzheimer Dis
, vol.18
, pp. 935-952
-
-
Cimini, A.1
Moreno, S.2
D'Amelio, M.3
Cristiano, L.4
D'Angelo, B.5
Falone, S.6
Benedetti, E.7
Carrara, P.8
Fanelli, F.9
Cecconi, F.10
Amicarelli, F.11
Cerù, M.P.12
-
19
-
-
67149112260
-
Neuronal response of peroxisomal and peroxisome-related proteins to chronic and acute Abeta injury
-
Cimini A, Benedetti E, D'Angelo B, Cristiano L, Falone S, Di Loreto S, Amicarelli F, Cerù MP: Neuronal response of peroxisomal and peroxisome-related proteins to chronic and acute Abeta injury. Curr Alzheimer Res 2009, 6:238-251.
-
(2009)
Curr Alzheimer Res
, vol.6
, pp. 238-251
-
-
Cimini, A.1
Benedetti, E.2
D'Angelo, B.3
Cristiano, L.4
Falone, S.5
Di Loreto, S.6
Amicarelli, F.7
Cerù, M.P.8
-
20
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G: Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 1996, 274:99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
21
-
-
33645520634
-
Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer 's disease
-
Jacobsen JS, Wu CC, Redwine JM, Comery TA, Arias R, Bowlby M, Martone R, Morrison JH, Pangalos MN, Reinhart PH, Bloom FE: Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer 's disease. Proc Natl Acad Sci USA 2006, 103:5161-5166.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 5161-5166
-
-
Jacobsen, J.S.1
Wu, C.C.2
Redwine, J.M.3
Comery, T.A.4
Arias, R.5
Bowlby, M.6
Martone, R.7
Morrison, J.H.8
Pangalos, M.N.9
Reinhart, P.H.10
Bloom, F.E.11
-
22
-
-
78650659370
-
Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease
-
D'Amelio M, Cavallucci V, Middei S, Marchetti C, Pacioni S, Ferri A, Diamantini A, De Zio D, Carrara P, Battistini L, Moreno S, Bacci A, Ammassari-Teule M, Marie H, Cecconi F: Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease. Nat Neurosci 2011, 14:69-76.
-
(2011)
Nat Neurosci
, vol.14
, pp. 69-76
-
-
D'Amelio, M.1
Cavallucci, V.2
Middei, S.3
Marchetti, C.4
Pacioni, S.5
Ferri, A.6
Diamantini, A.7
De Zio, D.8
Carrara, P.9
Battistini, L.10
Moreno, S.11
Bacci, A.12
Ammassari-Teule, M.13
Marie, H.14
Cecconi, F.15
-
23
-
-
84860151537
-
Impaired short-term plasticity in mossy fiber synapses caused by mitochondrial dysfunction of dentate granule cells is the earliest synaptic deficit in a mouse model of Alzheimer's disease
-
Lee SH, Kim KR, Ryu SY, Son S, Hong HS, Mook-Jung I, Lee SH, Ho WK: Impaired short-term plasticity in mossy fiber synapses caused by mitochondrial dysfunction of dentate granule cells is the earliest synaptic deficit in a mouse model of Alzheimer's disease. J Neurosci 2012, 32:5953-5963.
-
(2012)
J Neurosci
, vol.32
, pp. 5953-5963
-
-
Lee, S.H.1
Kim, K.R.2
Ryu, S.Y.3
Son, S.4
Hong, H.S.5
Mook-Jung, I.6
Lee, S.H.7
Ho, W.K.8
-
24
-
-
34247611481
-
Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment
-
Scheff SW, Price DA, Schmitt FA, DeKosky ST, Mufson EJ: Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology 2007, 68:1501-1508.
-
(2007)
Neurology
, vol.68
, pp. 1501-1508
-
-
Scheff, S.W.1
Price, D.A.2
Schmitt, F.A.3
DeKosky, S.T.4
Mufson, E.J.5
-
26
-
-
80053583204
-
New insights into the role of PPARs
-
Montagner A, Rando G, Degueurce G, Leuenberger N, Michalik L, Wahli W: New insights into the role of PPARs. Prostaglandins Leukot Essent Fatty Acids 2011, 85:235-243.
-
(2011)
Prostaglandins Leukot Essent Fatty Acids
, vol.85
, pp. 235-243
-
-
Montagner, A.1
Rando, G.2
Degueurce, G.3
Leuenberger, N.4
Michalik, L.5
Wahli, W.6
-
27
-
-
0025132245
-
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
-
Issemann I, Green S: Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 1990, 347:645-650.
-
(1990)
Nature
, vol.347
, pp. 645-650
-
-
Issemann, I.1
Green, S.2
-
28
-
-
41249085808
-
Molecular mechanism of PPAR in the regulation of age-related inflammation
-
Chung JH, Seo AY, Chung SW, Kim MK, Leeuwenburgh C, Yu BP, Chung HY: Molecular mechanism of PPAR in the regulation of age-related inflammation. Ageing Res Rev 2008, 7:126-136.
-
(2008)
Ageing Res Rev
, vol.7
, pp. 126-136
-
-
Chung, J.H.1
Seo, A.Y.2
Chung, S.W.3
Kim, M.K.4
Leeuwenburgh, C.5
Yu, B.P.6
Chung, H.Y.7
-
29
-
-
66049114500
-
Fat-induced satiety factor oleoylethanolamide enhances memory consolidation
-
Campolongo P, Roozendaal B, Trezza V, Cuomo V, Astarita G, Fu J, McGaugh JL, Piomelli D: Fat-induced satiety factor oleoylethanolamide enhances memory consolidation. PNAS 2009, 106:8027-8031.
-
(2009)
PNAS
, vol.106
, pp. 8027-8031
-
-
Campolongo, P.1
Roozendaal, B.2
Trezza, V.3
Cuomo, V.4
Astarita, G.5
Fu, J.6
McGaugh, J.L.7
Piomelli, D.8
-
30
-
-
64649093836
-
Biogenesis of peroxisomes and mitochondria: Linked by division
-
Delille HK, Alves R, Schrader M: Biogenesis of peroxisomes and mitochondria: linked by division. Histochem Cell Biol 2009, 131:441-446.
-
(2009)
Histochem Cell Biol
, vol.131
, pp. 441-446
-
-
Delille, H.K.1
Alves, R.2
Schrader, M.3
-
31
-
-
78650575544
-
Transcriptional coactivator PGC-1alpha promotes peroxisomal remodeling and biogenesis
-
Bagattin A, Hugendubler L, Mueller E: Transcriptional coactivator PGC-1alpha promotes peroxisomal remodeling and biogenesis. Proc Natl Acad Sci USA 2010, 107:20376-20381.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20376-20381
-
-
Bagattin, A.1
Hugendubler, L.2
Mueller, E.3
-
32
-
-
33744519453
-
Functional domains and dynamic assembly of the Peroxin Pex14p, the entry site of matrix proteins
-
Itoh R, Fujiki Y: Functional domains and dynamic assembly of the Peroxin Pex14p, the entry site of matrix proteins. J Biol Chem 2006, 281:10196-10205.
-
(2006)
J Biol Chem
, vol.281
, pp. 10196-10205
-
-
Itoh, R.1
Fujiki, Y.2
-
33
-
-
77649267086
-
The peroxisomal importomer constitutes a large and highly dynamic pore
-
Meinecke M, Cizmowski C, Schliebs W, Kruger V, Beck S, Wagner R, Erdmann R: The peroxisomal importomer constitutes a large and highly dynamic pore. Nat Cell Biol 2010, 12:273-277.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 273-277
-
-
Meinecke, M.1
Cizmowski, C.2
Schliebs, W.3
Kruger, V.4
Beck, S.5
Wagner, R.6
Erdmann, R.7
-
34
-
-
84859745968
-
Biochemically distinct vesicles from the endoplasmic reticulum fuse to form peroxisomes
-
van der Zand A, Gent J, Braakman I, Tabak HF: Biochemically distinct vesicles from the endoplasmic reticulum fuse to form peroxisomes. Cell 2012, 149:397-409.
-
(2012)
Cell
, vol.149
, pp. 397-409
-
-
Van Der Zand, A.1
Gent, J.2
Braakman, I.3
Tabak, H.F.4
-
35
-
-
35948979696
-
Differential expression of peroxisomal matrix and membrane proteins during postnatal development of mouse brain
-
Ahlemeyer B, Neubert I, Kovacs WJ, Baumgart-Vogt E: Differential expression of peroxisomal matrix and membrane proteins during postnatal development of mouse brain. J Comp Neurol 2007, 505:1-17.
-
(2007)
J Comp Neurol
, vol.505
, pp. 1-17
-
-
Ahlemeyer, B.1
Neubert, I.2
Kovacs, W.J.3
Baumgart-Vogt, E.4
-
36
-
-
0028124996
-
Characterization of human peroxisomal membrane proteins
-
Santos MJ, Kawada ME, Espeel M, Figueroa C, Alvarez A, Hidalgo U, Metz C: Characterization of human peroxisomal membrane proteins. J Biol Chem 1994, 269:24890-24896.
-
(1994)
J Biol Chem
, vol.269
, pp. 24890-24896
-
-
Santos, M.J.1
Kawada, M.E.2
Espeel, M.3
Figueroa, C.4
Alvarez, A.5
Hidalgo, U.6
Metz, C.7
-
37
-
-
84864052256
-
Peroxisomal ABC transporters: Structure, function and role in disease
-
Morita M, Imanaka T: Peroxisomal ABC transporters: Structure, function and role in disease. Biochim Biophys Acta 2012, 1822: 1387-1396.
-
(2012)
Biochim Biophys Acta
, vol.1822
, pp. 1387-1396
-
-
Morita, M.1
Imanaka, T.2
-
38
-
-
0028841708
-
Immunocytochemical localization of catalase in the central nervous system of the rat
-
Moreno S, Mugnaini E, Cerù MP: Immunocytochemical localization of catalase in the central nervous system of the rat. J Histochem Cytochem 1995, 43:1253 -1267.
-
(1995)
J Histochem Cytochem
, vol.43
, pp. 1253-1267
-
-
Moreno, S.1
Mugnaini, E.2
Cerù, M.P.3
-
39
-
-
0030668208
-
Regional and ultrastructural immunolocalization of copper-zinc superoxide dismutase in rat central nervous system
-
Moreno S, Nardacci R, Cerù MP: Regional and ultrastructural immunolocalization of copper-zinc superoxide dismutase in rat central nervous system. J Histochem Cytochem 1997, 45:1611-1622.
-
(1997)
J Histochem Cytochem
, vol.45
, pp. 1611-1622
-
-
Moreno, S.1
Nardacci, R.2
Cerù, M.P.3
-
40
-
-
62449166389
-
PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia
-
Qin W, Haroutunian V, Katsel P, Cardozo CP, Ho L, Buxbaum JD, Pasinetti GM: PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia. Arch Neurol 2009, 66:352-361.
-
(2009)
Arch Neurol
, vol.66
, pp. 352-361
-
-
Qin, W.1
Haroutunian, V.2
Katsel, P.3
Cardozo, C.P.4
Ho, L.5
Buxbaum, J.D.6
Pasinetti, G.M.7
-
41
-
-
44949210283
-
Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model
-
Hirata-Fukae C, Li HF, Hoe HS, Gray AJ, Minami SS, Hamada K, Niikura T, Hua F, Tsukagoshi-Nagai H, Horikoshi-Sakuraba Y, Mughal M, Rebeck GW, LaFerla FM, Mattson MP, Iwata N, Saido TC, Klein WL, Duff KE, Aisen PS, Matsuoka Y: Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model. Brain Res 2008, 1216:92-103.
-
(2008)
Brain Res
, vol.1216
, pp. 92-103
-
-
Hirata-Fukae, C.1
Li, H.F.2
Hoe, H.S.3
Gray, A.J.4
Minami, S.S.5
Hamada, K.6
Niikura, T.7
Hua, F.8
Tsukagoshi-Nagai, H.9
Horikoshi-Sakuraba, Y.10
Mughal, M.11
Rebeck, G.W.12
LaFerla, F.M.13
Mattson, M.P.14
Iwata, N.15
Saido, T.C.16
Klein, W.L.17
Duff, K.E.18
Aisen, P.S.19
Matsuoka, Y.20
more..
-
42
-
-
77957088739
-
Estrogen therapy and Alzheimer's dementia
-
Craig MC, Murphy DG: Estrogen therapy and Alzheimer's dementia. Ann N Y Acad Sci 2010, 1205:245-253.
-
(2010)
Ann N Y Acad Sci
, vol.1205
, pp. 245-253
-
-
Craig, M.C.1
Murphy, D.G.2
-
43
-
-
80052962821
-
A pathophysiological framework of hippocampal dysfunction in ageing and disease
-
Small SA, Schobel SA, Buxton RB, Witter MP, Barnes CA: A pathophysiological framework of hippocampal dysfunction in ageing and disease. Nat Rev Neurosci 2011, 12:585-601.
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 585-601
-
-
Small, S.A.1
Schobel, S.A.2
Buxton, R.B.3
Witter, M.P.4
Barnes, C.A.5
-
44
-
-
79956071527
-
PEX14 is required for microtubule-based peroxisome motility in human cells
-
Bharti P, Schliebs W, Schievelbusch T, Neuhaus A, David C, Kock K, Herrmann C, Meyer HE, Wiese S, Warscheid B, Theiss C, Erdmann R: PEX14 is required for microtubule-based peroxisome motility in human cells. J Cell Sci 2011, 124:1759-1768.
-
(2011)
J Cell Sci
, vol.124
, pp. 1759-1768
-
-
Bharti, P.1
Schliebs, W.2
Schievelbusch, T.3
Neuhaus, A.4
David, C.5
Kock, K.6
Herrmann, C.7
Meyer, H.E.8
Wiese, S.9
Warscheid, B.10
Theiss, C.11
Erdmann, R.12
-
45
-
-
79955454688
-
Amyloid-Beta interaction with mitochondria
-
Pagani L, Eckert A: Amyloid-Beta interaction with mitochondria. Int J Alzheimers Dis 2011, 2011:1-12.
-
(2011)
Int J Alzheimers Dis
, vol.2011
, pp. 1-12
-
-
Pagani, L.1
Eckert, A.2
-
46
-
-
70449435581
-
Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer's disease
-
Ferrer I: Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer's disease. J Bioenerg Biomembr 2009, 41:425-431.
-
(2009)
J Bioenerg Biomembr
, vol.41
, pp. 425-431
-
-
Ferrer, I.1
-
47
-
-
33847686377
-
Proteomic and functional alterations in brain mitochondria from Tg2576 mice occur before amyloid plaque deposition
-
Gillardon F, Rist W, Kussmaul L, Vogel J, Berg M, Danzer K, Kraut N, Hengerer B: Proteomic and functional alterations in brain mitochondria from Tg2576 mice occur before amyloid plaque deposition. Proteomics 2007, 7:605-616.
-
(2007)
Proteomics
, vol.7
, pp. 605-616
-
-
Gillardon, F.1
Rist, W.2
Kussmaul, L.3
Vogel, J.4
Berg, M.5
Danzer, K.6
Kraut, N.7
Hengerer, B.8
-
48
-
-
77956206298
-
A mitocentric view of Alzheimer's disease suggests multi-faceted treatments
-
Gibson GE, Shi Q: A mitocentric view of Alzheimer's disease suggests multi-faceted treatments. J Alzheimers Dis 2010, 2:S591-S607.
-
(2010)
J Alzheimers Dis
, vol.2
-
-
Gibson, G.E.1
Shi, Q.2
-
49
-
-
77955981090
-
Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models
-
Nicholson RM, Kusne Y, Nowak LA, LaFerla FM, Reiman EM, Valla J: Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models. Brain Res 2010, 1347:179-185.
-
(2010)
Brain Res
, vol.1347
, pp. 179-185
-
-
Nicholson, R.M.1
Kusne, Y.2
Nowak, L.A.3
LaFerla, F.M.4
Reiman, E.M.5
Valla, J.6
-
50
-
-
57649187117
-
Brain glucose hypometabolism and oxidative stress in preclinical Alzheimer's disease
-
Mosconi L, Pupi A, De Leon MJ: Brain glucose hypometabolism and oxidative stress in preclinical Alzheimer's disease. Ann N Y Acad Sci 2008, 1147:180-195.
-
(2008)
Ann N Y Acad Sci
, vol.1147
, pp. 180-195
-
-
Mosconi, L.1
Pupi, A.2
De Leon, M.J.3
-
51
-
-
81855164838
-
Shift in brain metabolism in late onset Alzheimer's disease: Implications for biomarkers and therapeutic interventions
-
Yao J, Rettberg JR, Klosinski LP, Cadenas E, Brinton RD: Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions. Mol Aspects Med 2011, 32:247-257.
-
(2011)
Mol Aspects Med
, vol.32
, pp. 247-257
-
-
Yao, J.1
Rettberg, J.R.2
Klosinski, L.P.3
Cadenas, E.4
Brinton, R.D.5
-
52
-
-
84861658605
-
Evidence of oxidative stress in very long chain fatty acid - treated oligodendrocytes and potentialization of ROS production using RNA interference-directed knockdown of ABCD1 and ACOX1 peroxisomal proteins
-
Baarine M, Andréoletti P, Athias A, Nury T, Zarrouk A, Ragot K, Vejux A, Riedinger JM, Kattan Z, Bessede G, Trompier D, Savary S, Cherkaoui-Malki M, Lizard G: Evidence of oxidative stress in very long chain fatty acid - treated oligodendrocytes and potentialization of ROS production using RNA interference-directed knockdown of ABCD1 and ACOX1 peroxisomal proteins. Neuroscience 2012, 213:1-18.
-
(2012)
Neuroscience
, vol.213
, pp. 1-18
-
-
Baarine, M.1
Andréoletti, P.2
Athias, A.3
Nury, T.4
Zarrouk, A.5
Ragot, K.6
Vejux, A.7
Riedinger, J.M.8
Kattan, Z.9
Bessede, G.10
Trompier, D.11
Savary, S.12
Cherkaoui-Malki, M.13
Lizard, G.14
-
53
-
-
84866159844
-
Induction of mitochondrial changes associated with oxidative stress on very long chain fatty acids (C22:0, C24:0, or C26:0)-treated human neuronal cells (SK-NB-E)
-
doi:10.1155/2012/623257
-
Zarrouk A, Vejux A, Nury T, El Hajj HI, Haddad M, Cherkaoui-Malki M, Riedinger JM, Hammami M, Lizard G: Induction of mitochondrial changes associated with oxidative stress on very long chain fatty acids (C22:0, C24:0, or C26:0)-treated human neuronal cells (SK-NB-E). Oxid Med Cell Longev 2012, doi:10.1155/2012/623257.
-
(2012)
Oxid Med Cell Longev
-
-
Zarrouk, A.1
Vejux, A.2
Nury, T.3
El Hajj, H.I.4
Haddad, M.5
Cherkaoui-Malki, M.6
Riedinger, J.M.7
Hammami, M.8
Lizard, G.9
-
54
-
-
33748422385
-
Differential regulation of the cynomolgus, human, and rat acyl-CoA oxidase promoters by PPARalpha
-
Kane CD, Francone OL, Stevens KA: Differential regulation of the cynomolgus, human, and rat acyl-CoA oxidase promoters by PPARalpha. Gene 2006, 380:84-94.
-
(2006)
Gene
, vol.380
, pp. 84-94
-
-
Kane, C.D.1
Francone, O.L.2
Stevens, K.A.3
-
55
-
-
79954531943
-
Peroxisome proliferator-activated receptor-α agonists protect cortical neurons from inflammatory mediators and improve peroxisomal function
-
Gray E, Ginty M, Kemp K, Scolding N, Wilkins A: Peroxisome proliferator-activated receptor-α agonists protect cortical neurons from inflammatory mediators and improve peroxisomal function. Eur J Neurosci 2011, 33:1421-1432.
-
(2011)
Eur J Neurosci
, vol.33
, pp. 1421-1432
-
-
Gray, E.1
Ginty, M.2
Kemp, K.3
Scolding, N.4
Wilkins, A.5
-
56
-
-
35748953472
-
Induction of endogenous uncoupling protein 3 suppresses mitochondrial oxidant emission during fatty acid-supported respiration
-
Anderson EJ, Yamazaki H, Neufer PD: Induction of endogenous uncoupling protein 3 suppresses mitochondrial oxidant emission during fatty acid-supported respiration. J Biol Chem 2007, 282:31257-31266.
-
(2007)
J Biol Chem
, vol.282
, pp. 31257-31266
-
-
Anderson, E.J.1
Yamazaki, H.2
Neufer, P.D.3
-
57
-
-
3042736860
-
Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: Up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease
-
Reddy PH, McWeeney S, Park BS, Manczak M, Gutala RV, Partovi D, Jung Y, Yau V, Searles R, Mori M, Quinn J: Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease. Hum Mol Genet 2004, 13:1225-1240.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1225-1240
-
-
Reddy, P.H.1
McWeeney, S.2
Park, B.S.3
Manczak, M.4
Gutala, R.V.5
Partovi, D.6
Jung, Y.7
Yau, V.8
Searles, R.9
Mori, M.10
Quinn, J.11
-
58
-
-
33646369421
-
Lack of glutathione peroxidase-1 exacerbates αβ-mediated neurotoxicity in cortical neurons
-
Crack PJ, Cimdins K, Ali U, Hertzog PJ, Iannello RC: Lack of glutathione peroxidase-1 exacerbates αβ-mediated neurotoxicity in cortical neurons. J Neural Transm 2006, 113: 645-657.
-
(2006)
J Neural Transm
, vol.113
, pp. 645-657
-
-
Crack, P.J.1
Cimdins, K.2
Ali, U.3
Hertzog, P.J.4
Iannello, R.C.5
-
59
-
-
0033813152
-
Overexpression of glutathione peroxidase increases the resistance of neuronal cells to Abeta-mediated neurotoxicity
-
Barkats M, Millecamps S, Abrioux P, Geoffroy MC, Mallet J: Overexpression of glutathione peroxidase increases the resistance of neuronal cells to Abeta-mediated neurotoxicity. J Neurochem 2000, 75:1438-1446.
-
(2000)
J Neurochem
, vol.75
, pp. 1438-1446
-
-
Barkats, M.1
Millecamps, S.2
Abrioux, P.3
Geoffroy, M.C.4
Mallet, J.5
-
60
-
-
80052000670
-
Glutathione peroxidase-1 in health and disease: From molecular mechanisms to therapeutic opportunities
-
Lubos E, Loscalzo J, Handy DE: Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal 2011, 15:1957-1997.
-
(2011)
Antioxid Redox Signal
, vol.15
, pp. 1957-1997
-
-
Lubos, E.1
Loscalzo, J.2
Handy, D.E.3
-
61
-
-
37249074786
-
Oxidative modification to cysteine sulfonic acid of Cys111 in human copper-zinc superoxide dismutase
-
Fujiwara N, Nakano M, Kato S, Yoshihara D, Ookawara T, Eguchi H, Taniguchi N, Suzuki K: Oxidative modification to cysteine sulfonic acid of Cys111 in human copper-zinc superoxide dismutase. J Biol Chem 2007, 282:35933-35944.
-
(2007)
J Biol Chem
, vol.282
, pp. 35933-35944
-
-
Fujiwara, N.1
Nakano, M.2
Kato, S.3
Yoshihara, D.4
Ookawara, T.5
Eguchi, H.6
Taniguchi, N.7
Suzuki, K.8
-
62
-
-
84455161651
-
SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer disease
-
Murakami K, Murata N, Noda Y, Tahara S, Kaneko T, Kinoshita N, Hatsuta H, Murayama S, Barnham KJ, Irie K, Shirasawa T, Shimizu T: SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer disease. J Biol Chem 2011, 286: 44557-44568.
-
(2011)
J Biol Chem
, vol.286
, pp. 44557-44568
-
-
Murakami, K.1
Murata, N.2
Noda, Y.3
Tahara, S.4
Kaneko, T.5
Kinoshita, N.6
Hatsuta, H.7
Murayama, S.8
Barnham, K.J.9
Irie, K.10
Shirasawa, T.11
Shimizu, T.12
-
63
-
-
84863229362
-
The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons
-
Nunomura A, Tamaoki T, Motohashi N, Nakamura M, McKeel DW Jr, Tabaton M, Lee HG, Smith MA, Perry G, Zhu X: The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons. J Neuropathol Exp Neurol 2012, 71:233-241.
-
(2012)
J Neuropathol Exp Neurol
, vol.71
, pp. 233-241
-
-
Nunomura, A.1
Tamaoki, T.2
Motohashi, N.3
Nakamura, M.4
McKeel Jr., D.W.5
Tabaton, M.6
Lee, H.G.7
Smith, M.A.8
Perry, G.9
Zhu, X.10
-
64
-
-
77957256030
-
Role of by-products of lipid oxidation in Alzheimer's disease brain: A focus on acrolein
-
Singh M, Nam DT, Arseneault M, Ramassamy C: Role of by-products of lipid oxidation in Alzheimer's disease brain: a focus on acrolein. J Alzheimers Dis 2010, 21:741-756.
-
(2010)
J Alzheimers Dis
, vol.21
, pp. 741-756
-
-
Singh, M.1
Nam, D.T.2
Arseneault, M.3
Ramassamy, C.4
-
65
-
-
77953659232
-
Potential role of acrolein in neurodegeneration and in Alzheimer's disease
-
Dang TN, Arseneault M, Murthy V, Ramassamy C: Potential role of acrolein in neurodegeneration and in Alzheimer's disease. Curr Mol Pharmacol 2010, 3:66-78.
-
(2010)
Curr Mol Pharmacol
, vol.3
, pp. 66-78
-
-
Dang, T.N.1
Arseneault, M.2
Murthy, V.3
Ramassamy, C.4
-
66
-
-
84866935704
-
Inhibition of peroxisomal β-oxidation by thioridazine increases the amount of VLCFAs and Aβ generation in the rat brain
-
Shi R, Zhang Y, Shi Y, Shi S, Jiang L: Inhibition of peroxisomal β-oxidation by thioridazine increases the amount of VLCFAs and Aβ generation in the rat brain. Neurosci Lett 2012, 528:6-10.
-
(2012)
Neurosci Lett
, vol.528
, pp. 6-10
-
-
Shi, R.1
Zhang, Y.2
Shi, Y.3
Shi, S.4
Jiang, L.5
-
67
-
-
58849090439
-
Transcribe to survive: Transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease
-
Clark J, Simon DK: Transcribe to survive: transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease. Antioxid Redox Signal 2009, 11:509-528.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 509-528
-
-
Clark, J.1
Simon, D.K.2
-
68
-
-
84555200221
-
Mitochondria and PGC-1α in aging and Age-associated diseases
-
Wenz T: Mitochondria and PGC-1α in aging and Age-associated diseases. J Aging Res 2011, 2011:1-12.
-
(2011)
J Aging Res
, vol.2011
, pp. 1-12
-
-
Wenz, T.1
-
69
-
-
84863230675
-
Age-dependent and tissue-related glutathione redox status in a mouse model of Alzheimer's disease
-
Zhang C, Rodriguez C, Spaulding J, Aw TY, Feng J: Age-dependent and tissue-related glutathione redox status in a mouse model of Alzheimer's disease. J Alzheimers Dis 2012, 28:655-666.
-
(2012)
J Alzheimers Dis
, vol.28
, pp. 655-666
-
-
Zhang, C.1
Rodriguez, C.2
Spaulding, J.3
Aw, T.Y.4
Feng, J.5
-
70
-
-
38949123654
-
Lipid peroxidation and antioxidant enzyme activities in vascular and Alzheimer dementias
-
Casado A, Encarnación López-Fernández M, Concepción Casado M, de La Torre R: Lipid peroxidation and antioxidant enzyme activities in vascular and Alzheimer dementias. Neurochem Res 2008, 33:450-458.
-
(2008)
Neurochem Res
, vol.33
, pp. 450-458
-
-
Casado, A.1
Encarnación López-Fernández, M.2
Concepción Casado, M.3
De La Torre, R.4
-
71
-
-
69449096141
-
Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease
-
Massaad CA, Washington TM, Pautler RG, Klann E: Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 2009, 106:13576-13581.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 13576-13581
-
-
Massaad, C.A.1
Washington, T.M.2
Pautler, R.G.3
Klann, E.4
-
72
-
-
0032191725
-
Astrocyte changes in aging cerebral cortex and hippocampus: A quantitative immunohistochemical study
-
Amenta F, Bronzetti E, Sabbatini M, Vega JA: Astrocyte changes in aging cerebral cortex and hippocampus: a quantitative immunohistochemical study. Microsc Res Tech 1998, 43:29-33.
-
(1998)
Microsc Res Tech
, vol.43
, pp. 29-33
-
-
Amenta, F.1
Bronzetti, E.2
Sabbatini, M.3
Vega, J.A.4
-
74
-
-
79951707099
-
Astrocytes: Implications for neuroinflammatory pathogenesis of Alzheimer's disease
-
Li C, Zhao R, Gao K, Wei Z, Yin MY, Lau LT, Chui D, Hoi Yu AC: Astrocytes: implications for neuroinflammatory pathogenesis of Alzheimer's disease. Curr Alzheimer Res 2011, 8:67-80.
-
(2011)
Curr Alzheimer Res
, vol.8
, pp. 67-80
-
-
Li, C.1
Zhao, R.2
Gao, K.3
Wei, Z.4
Yin, M.Y.5
Lau, L.T.6
Chui, D.7
Hoi Yu, A.C.8
-
75
-
-
0018118471
-
Microperoxisomes in the central nervous system of the postnatal rat
-
Arnold G, Holtzman E: Microperoxisomes in the central nervous system of the postnatal rat. Brain Res 1978, 155:1-17.
-
(1978)
Brain Res
, vol.155
, pp. 1-17
-
-
Arnold, G.1
Holtzman, E.2
-
76
-
-
0027303991
-
Purification of peroxisomal fraction from rat brain
-
Cimini A, Moreno S, Giorgi M, Serafini B, Cerú MP: Purification of peroxisomal fraction from rat brain. Neurochem Int 1993, 23:249-260.
-
(1993)
Neurochem Int
, vol.23
, pp. 249-260
-
-
Cimini, A.1
Moreno, S.2
Giorgi, M.3
Serafini, B.4
Cerú, M.P.5
-
77
-
-
0032538129
-
Presence of heterogeneous peroxisomal populations in the rat nervous tissue
-
Cimini A, Singh I, Farioli-Vecchioli S, Cristiano L, Cerú MP: Presence of heterogeneous peroxisomal populations in the rat nervous tissue. Biochim Biophys Acta 1998, 1425:13-26.
-
(1998)
Biochim Biophys Acta
, vol.1425
, pp. 13-26
-
-
Cimini, A.1
Singh, I.2
Farioli-Vecchioli, S.3
Cristiano, L.4
Cerú, M.P.5
-
78
-
-
79955100322
-
Oxidative stress and the aging brain: From theory to prevention
-
Brain aging: models, methods, and mechanisms. Edited by Riddle DR. Boca Raton (FL): CRC Press; Chapter 15
-
Gemma C, Vila J, Bachstetter A, Bickford PC: Oxidative stress and the aging brain: from theory to prevention. In Brain aging: models, methods, and mechanisms. Edited by Riddle DR. Boca Raton (FL): CRC Press; 2007:Chapter 15. Frontiers in Neuroscience.
-
(2007)
Frontiers in Neuroscience
-
-
Gemma, C.1
Vila, J.2
Bachstetter, A.3
Bickford, P.C.4
-
79
-
-
84867785427
-
Redox status and bioenergetics liaison in cancer and neurodegeneration
-
Filomeni G, Bolaños JP, Mastroberardino PG: Redox status and bioenergetics liaison in cancer and neurodegeneration. Int J Cell Bio 2012, 2012:659645.
-
(2012)
Int J Cell Bio
, vol.2012
, pp. 659645
-
-
Filomeni, G.1
Bolaños, J.P.2
Mastroberardino, P.G.3
-
80
-
-
51349168245
-
Activated microglia modulate astroglial enzymes involved in oxidative and inflammatory stress and increase the resistance of astrocytes to oxidative stress in vitro
-
Röhl C, Armbrust E, Kolbe K, Lucius R, Maser E, Venz S, Gülden M: Activated microglia modulate astroglial enzymes involved in oxidative and inflammatory stress and increase the resistance of astrocytes to oxidative stress in vitro. Glia 2008, 56:1114-1126.
-
(2008)
Glia
, vol.56
, pp. 1114-1126
-
-
Röhl, C.1
Armbrust, E.2
Kolbe, K.3
Lucius, R.4
Maser, E.5
Venz, S.6
Gülden, M.7
-
81
-
-
0034733705
-
Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc
-
Cuajungco MP, Goldstein LE, Nunomura A, Smith MA, Lim JT, Atwood CS, Huang X, Farrag YW, Perry G, Bush AI: Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc. J Biol Chem 2000, 275:19439-19442.
-
(2000)
J Biol Chem
, vol.275
, pp. 19439-19442
-
-
Cuajungco, M.P.1
Goldstein, L.E.2
Nunomura, A.3
Smith, M.A.4
Lim, J.T.5
Atwood, C.S.6
Huang, X.7
Farrag, Y.W.8
Perry, G.9
Bush, A.I.10
-
82
-
-
80052934408
-
RNA oxidation adducts 8-OHG and 8-OHA change with Aβ42 levels in late-stage Alzheimer 's disease
-
Weidner AM, Bradley MA, Beckett TL, Niedowicz DM, Dowling AL, Matveev SV, LeVine H 3rd, Lovell MA, Murphy MP: RNA oxidation adducts 8-OHG and 8-OHA change with Aβ42 levels in late-stage Alzheimer 's disease. PLoS One 2011, 6:1-6.
-
(2011)
PLoS One
, vol.6
, pp. 1-6
-
-
Weidner, A.M.1
Bradley, M.A.2
Beckett, T.L.3
Niedowicz, D.M.4
Dowling, A.L.5
Matveev, S.V.6
LeVine III, H.7
Lovell, M.A.8
Murphy, M.P.9
-
83
-
-
0033499883
-
Immunocytochemical localization of D-amino acid oxidase in rat brain
-
Moreno S, Nardacci R, Cimini A, Cerù MP: Immunocytochemical localization of D-amino acid oxidase in rat brain. J Neurocytol 1999, 28:169-185.
-
(1999)
J Neurocytol
, vol.28
, pp. 169-185
-
-
Moreno, S.1
Nardacci, R.2
Cimini, A.3
Cerù, M.P.4
-
84
-
-
0035175177
-
Immunocytochemical localization of acyl-CoA oxidase in the rat central nervous system
-
Farioli-Vecchioli S, Moreno S, Cerù MP: Immunocytochemical localization of acyl-CoA oxidase in the rat central nervous system. J Neurocytol 2001, 30:21-33.
-
(2001)
J Neurocytol
, vol.30
, pp. 21-33
-
-
Farioli-Vecchioli, S.1
Moreno, S.2
Cerù, M.P.3
-
85
-
-
84867463345
-
Alzheimer's drugs take a new tack
-
Callaway E: Alzheimer's drugs take a new tack. Nature 2012, 489:13-14.
-
(2012)
Nature
, vol.489
, pp. 13-14
-
-
Callaway, E.1
-
86
-
-
84866456583
-
Preventing Alzheimer's disease
-
Selkoe DJ: Preventing Alzheimer's disease. Science 2012, 337:1488-1492.
-
(2012)
Science
, vol.337
, pp. 1488-1492
-
-
Selkoe, D.J.1
-
87
-
-
0017184389
-
Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM: Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
|