Effects of steroidal aromatase inhibitors on sensitive and resistant breast cancer cells: Aromatase inhibition and autophagy

Journal of Steroid Biochemistry and Molecular Biology

Volumn 135, Issue 1, 2013, Pages 51-59

  Amaral, Cristina ^a,b   Varela, Carla ^c   Azevedo, Margarida ^a   Da Silva, Elisiário Tavares ^c   Roleira, Fernanda M F ^c   Chen, Shiuan ^d   Correia Da Silva, Georgina ^a,b   Teixeira, Natércia ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Aromatase inhibition; Autophagy; Endocrine resistance; Exemestane; Hormone dependent breast cancer; Steroidal aromatase inhibitors

Indexed keywords

3 METHYLADENINE; 3BETA HYDROXYANDROST 4 EN 17 ONE; 4ALPHA,5ALPHA EPOXYANDROSTAN 17 ONE; 5ALPHA ANDROST 2 EN 17 ONE; ANDROST 4 EN 17 ONE; ANDROSTENEDIONE; AROMATASE; AROMATASE INHIBITOR; ESTROGEN RECEPTOR; EXEMESTANE; PHOSPHATIDYLINOSITOL 3 KINASE; TAMOXIFEN; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; BREAST CANCER; CANCER CELL; CELL VIABILITY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; SYNTHESIS;

ADENINE; ANDROSTANES; AROMATASE INHIBITORS; AUTOPHAGY; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; ESTROGEN ANTAGONISTS; FEMALE; HUMANS; MCF-7 CELLS; NEOPLASMS, HORMONE-DEPENDENT; PHOSPHATIDYLINOSITOL 3-KINASES; RECEPTORS, ESTROGEN; TESTOSTERONE;

EID: 84873021507     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2012.12.017     Document Type: Article

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