Interleukin-1 promotes coagulation, which is necessary for protective immunity in the lung against streptococcus pneumoniae infection

Journal of Infectious Diseases

Volumn 207, Issue 1, 2013, Pages 50-60

  Yang, Hyungjun ^a,b   Ko, Hyun Jeong ^a,c   Yang, Jin Young ^a   Kim, Jae Jin ^a   Seo, Sang Uk ^a   Park, Seung Gu ^d   Choi, Sun Shim ^d   Seong, Je Kyung ^b,e   Kweon, Mi Na ^a  

^a International Vaccine Institute   (South Korea)

^b Seoul National University   (South Korea)

^c Kangwon National University   (South Korea)

^d Kangwon National University   (South Korea)

^e Seoul National University   (South Korea)

Author keywords

Coagulation; Fibrinogen; IL 1; Innate immunity; S. pneumoniae

Indexed keywords

CD11B ANTIGEN; CYTOKINE; FIBRINOGEN; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; STAT3 PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL TISSUE; ARTICLE; HOST RESISTANCE; IMMUNITY; INNATE IMMUNITY; LOWER RESPIRATORY TRACT; LUNG INFILTRATE; MORTALITY; MOUSE; NEUTROPHIL; NONHUMAN; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; RESPIRATORY SYSTEM; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; WILD TYPE;

ANIMALS; BLOOD COAGULATION; DISEASE SUSCEPTIBILITY; DOWN-REGULATION; FIBRINOGEN; IMMUNITY, INNATE; INTERLEUKIN-1; LUNG; MICE; MICE, INBRED C57BL; MUTATION; NEUTROPHILS; PNEUMONIA, PNEUMOCOCCAL; RECEPTORS, INTERLEUKIN-1; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SPECIFIC PATHOGEN-FREE ORGANISMS; STREPTOCOCCUS PNEUMONIAE; SURVIVAL ANALYSIS; THROMBIN;

EID: 84872967043     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jis651     Document Type: Article

References (47)

1. Hollingshead SK, Briles DE. Streptococcus pneumoniae: new tools for an old pathogen. Curr Opin Microbiol 2001; 4:71-7.
2. van der Poll T, Opal SM. Pathogenesis, treatment, and prevention of pneumococcal pneumonia. Lancet 2009; 374:1543-56.
3. O'Brien KL, Walters MI, Sellman J, et al. Severe pneumococcal pneumonia in previously healthy children: the role of preceding influenza infection. Clin Infect Dis 2000; 30:784-9.
4. McCullers JA. Effect of antiviral treatment on the outcome of secondary bacterial pneumonia after influenza. J Infect Dis 2004; 190:519-26.
5. Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124:783-801.
6. Malley R, Henneke P, Morse SC, et al. Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection. Proc Natl Acad Sci U S A 2003; 100:1966-71.
7. Jones MR, Simms BT, Lupa MM, Kogan MS, Mizgerd JP. Lung NFkappaB activation and neutrophil recruitment require IL-1 and TNF receptor signaling during pneumococcal pneumonia. J Immunol 2005; 175:7530-5.
8. Loof TG, Morgelin M, Johansson L, et al. Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense. Blood 2011; 118:2589-98.
9. Tennent GA, Brennan SO, Stangou AJ, O'Grady J, Hawkins PN, Pepys MB. Human plasma fibrinogen is synthesized in the liver. Blood 2007; 109:1971-4.
10. Massberg S, Grahl L, von Bruehl ML, et al. Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases. Nat Med 2010; 16:887-96.
11. Glaccum MB, Stocking KL, Charrier K, et al. Phenotypic and functional characterization of mice that lack the type I receptor for IL-1. J Immunol 1997; 159:3364-71.
12. Park SM, Ko HJ, Shim DH, et al. MyD88 signaling is not essential for induction of antigen-specific B cell responses but is indispensable for protection against Streptococcus pneumoniae infection following oral vaccination with attenuated Salmonella expressing PspA antigen. J Immunol 2008; 181:6447-55.
13. Seo SU, Kwon HJ, Ko HJ, et al. Type I interferon signaling regulates Ly6Chi monocytes and neutrophils during acute viral pneumonia in mice. PLoS Pathog 2011; 7:e1001304.
14. Mijares LA, Wangdi T, Sokol C, Homer R, Medzhitov R, Kazmierczak BI. Airway epithelial MyD88 restores control of Pseudomonas aeruginosa murine infection via an IL-1-dependent pathway. J Immunol 2011; 186:7080-8.
15. Dockrell DH, Marriott HM, Prince LR, et al. Alveolar macrophage apoptosis contributes to pneumococcal clearance in a resolving model of pulmonary infection. J Immunol 2003; 171:5380-8.
16. Duan HO, Simpson-Haidaris PJ. Cell type-specific differential induction of the human gamma-fibrinogen promoter by interleukin-6. J Biol Chem 2006; 281:12451-7.
17. Yamamoto M, Yamazaki S, Uematsu S, et al. Regulation of Toll/IL-1- receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta. Nature 2004; 430:218-22.
18. Duan HO, Simpson-Haidaris PJ. Functional analysis of interleukin 6 response elements (IL-6REs) on the human gamma-fibrinogen promoter: binding of hepatic Stat3 correlates negatively with transactivation potential of type II IL-6REs. J Biol Chem 2003; 278:41270-81.
19. Lin L, Amin R, Gallicano GI, et al. The STAT3 inhibitor NSC 74859 is effective in hepatocellular cancers with disrupted TGF-beta signaling. Oncogene 2009; 28:961-72.
20. Fong Y, Lowry SF. Tumor necrosis factor in the pathophysiology of infection and sepsis. Clin Immunol Immunopathol 1990; 55:157-70.
21. Calbo E, Garau J. Of mice and men: innate immunity in pneumococcal pneumonia. Int J Antimicrob Agents 2010; 35:107-13.
22. Bergeron Y, Ouellet N, Deslauriers AM, Simard M, Olivier M, Bergeron MG. Cytokine kinetics and other host factors in response to pneumococcal pulmonary infection in mice. Infect Immun 1998; 66:912-22.
23. Dinarello CA. Immunological and inflammatory functions of the interleukin- 1 family. Annu Rev Immunol 2009; 27:519-50.
24. O'Neill LA. The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress. Immunol Rev 2008; 226:10-8.
25. Zwijnenburg PJ, van der Poll T, Florquin S, Roord JJ, Van Furth AM. IL-1 receptor type 1 gene-deficient mice demonstrate an impaired host defense against pneumococcal meningitis. J Immunol 2003; 170:4724-30.
26. Kafka D, Ling E, Feldman G, et al. Contribution of IL-1 to resistance to Streptococcus pneumoniae infection. Int Immunol 2008; 20:1139-46.
27. Brinkmann V, Reichard U, Goosmann C, et al. Neutrophil extracellular traps kill bacteria. Science 2004; 303:1532-5.
28. Stokes CA, Ismail S, Dick EP, et al. Role of interleukin-1 and MyD88- dependent signaling in rhinovirus infection. J Virol 2011; 85:7912-21.
29. Wajant H, Scheurich P. TNFR1-induced activation of the classical NF-kappaB pathway. FEBS J 2011; 278:862-76.
30. Rijneveld AW, Florquin S, Branger J, Speelman P, Van Deventer SJ, van der Poll T. TNF-alpha compensates for the impaired host defense of IL-1 type I receptor-deficient mice during pneumococcal pneumonia. J Immunol 2001; 167:5240-6.
31. Ray CA, Lasbury ME, Durant PJ, et al. Transforming growth factorbeta activation and signaling in the alveolar environment during Pneumocystis pneumonia. J Eukaryot Microbiol 2006; 53 (Suppl 1): S127-9.
32. Mahavadi P, Korfei M, Henneke I, et al. Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia. Am J Respir Crit Care Med 2010; 182:207-19.
33. Marriott HM, Dockrell DH. Streptococcus pneumoniae: the role of apoptosis in host defense and pathogenesis. Int J Biochem Cell Biol 2006; 38:1848-54.
34. Vasse M, Paysant J, Soria J, Collet JP, Vannier JP, Soria C. Regulation of fibrinogen biosynthesis by cytokines, consequences on the vascular risk. Haemostasis 1996; 26 (Suppl 4):331-9.
35. Haidaris PJ. Induction of fibrinogen biosynthesis and secretion from cultured pulmonary epithelial cells. Blood 1997; 89:873-82.
36. Simpson-Haidaris PJ, Courtney MA, Wright TW, Goss R, Harmsen AGigliotti F. Induction of fibrinogen expression in the lung epithelium during Pneumocystis carinii pneumonia. Infect Immun 1998; 66:4431-9.
37. Bode JG, Albrecht U, Haussinger D, Heinrich PC, Schaper F. Hepatic acute phase proteins: regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-kappaB-dependent signaling. Eur J Cell Biol 2012; 91:496-505.
38. Skovgaard K, Mortensen S, Boye M, Hedegaard J, Heegaard PM. Hepatic gene expression changes in pigs experimentally infected with the lung pathogen Actinobacillus pleuropneumoniae as analyzed with an innate immunity focused microarray. Innate Immun 2010; 16:343-53.
39. Duan J, Chung H, Troy E, Kasper DL. Microbial colonization drives expansion of IL-1 receptor 1-expressing and IL-17-producing gamma/ delta T cells. Cell Host Microbe 2010; 7:140-50.
40. Amara U, Rittirsch D, Flierl M, et al. Interaction between the coagulation and complement system. Adv Exp Med Biol 2008; 632:71-9.
41. McAdow M, Kim HK, Dedent AC, Hendrickx AP, Schneewind O, Missiakas DM. Preventing Staphylococcus aureus sepsis through the inhibition of its agglutination in blood. PLoS Pathog 2011; 7: e1002307.
42. Mullarky IK, Szaba FM, Berggren KN, et al. Infection-stimulated fibrin deposition controls hemorrhage and limits hepatic bacterial growth during listeriosis. Infect Immun 2005; 73:3888-95.
43. Johnson LL, Berggren KN, Szaba FM, Chen W, Smiley ST. Fibrinmediated protection against infection-stimulated immunopathology. J Exp Med 2003; 197:801-6.
44. Rijneveld AW, Weijer S, Bresser P, et al. Local activation of the tissue factor-factor VIIa pathway in patients with pneumonia and the effect of inhibition of this pathway in murine pneumococcal pneumonia. Crit Care Med 2006; 34:1725-30.
45. Jansen PM, Boermeester MA, Fischer E, et al. Contribution of interleukin- 1 to activation of coagulation and fibrinolysis, neutrophil degranulation, and the release of secretory-type phospholipase A2 in sepsis: studies in nonhuman primates after interleukin-1 alpha administration and during lethal bacteremia. Blood 1995; 86:1027-34.
46. Henderson C, Goldbach-Mansky R. Monogenic IL-1 mediated autoinflammatory and immunodeficiency syndromes: finding the right balance in response to danger signals. Clin Immunol 2010; 135:210-22.
47. Rijneveld AW, Florquin S, Speelman P, Edwards CK, Dinarello CA, van der Poll T. Interleukin-1 receptor antagonist transiently impairs antibacterial defense but not survival in murine pneumococcal pneumonia. Eur Cytokine Netw 2003; 14:242-5.