메뉴 건너뛰기




Volumn 33, Issue 2, 2013, Pages 378-386

Mitogen-activated protein kinase 14 is a novel negative regulatory switch for the vascular smooth muscle cell contractile gene program

Author keywords

differentiation; myocardin; p38 mitogen activated protein kinase; smooth muscle

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOCARDIN; SERUM RESPONSE FACTOR;

EID: 84872926889     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.300645     Document Type: Article
Times cited : (25)

References (67)
  • 1
    • 3042588831 scopus 로고    scopus 로고
    • Molecular regulation of vascular smooth muscle cell differentiation in development and disease
    • Owens GK, Kumar MS, Wamhoff BR. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev. 2004;84:767-801.
    • (2004) Physiol Rev. , vol.84 , pp. 767-801
    • Owens, G.K.1    Kumar, M.S.2    Wamhoff, B.R.3
  • 2
    • 79957655520 scopus 로고    scopus 로고
    • Can microRNAs control vascular smooth muscle phenotypic modulation and the response to injury?
    • Albinsson S, Sessa WC. Can microRNAs control vascular smooth muscle phenotypic modulation and the response to injury? Physiol Genomics. 2011;43:529-533.
    • (2011) Physiol Genomics. , vol.43 , pp. 529-533
    • Albinsson, S.1    Sessa, W.C.2
  • 3
    • 84857293493 scopus 로고    scopus 로고
    • Epigenetic control of smooth muscle cell differentiation and phenotypic switching in vascular development and disease
    • Alexander MR, Owens GK. Epigenetic control of smooth muscle cell differentiation and phenotypic switching in vascular development and disease. Annu Rev Physiol. 2012;74:13-40.
    • (2012) Annu Rev Physiol. , vol.74 , pp. 13-40
    • Alexander, M.R.1    Owens, G.K.2
  • 4
    • 0344392240 scopus 로고    scopus 로고
    • Transdifferentiation of mouse aortic smooth muscle cells to a macrophage-like state after cholesterol loading
    • Rong JX, Shapiro M, Trogan E, Fisher EA. Transdifferentiation of mouse aortic smooth muscle cells to a macrophage-like state after cholesterol loading. Proc Natl Acad Sci USA. 2003;100:13531-13536.
    • (2003) Proc Natl Acad Sci USA. , vol.100 , pp. 13531-13536
    • Rong, J.X.1    Shapiro, M.2    Trogan, E.3    Fisher, E.A.4
  • 8
  • 9
    • 43449095311 scopus 로고    scopus 로고
    • Stem cells and transplant arteriosclerosis
    • Xu Q. Stem cells and transplant arteriosclerosis. Circ Res. 2008;102:1011-1024.
    • (2008) Circ Res. , vol.102 , pp. 1011-1024
    • Xu, Q.1
  • 10
    • 0034283415 scopus 로고    scopus 로고
    • Retinoids: Versatile biological response modifers of vascular smooth muscle phenotype
    • Miano JM, Berk BC. Retinoids: versatile biological response modifers of vascular smooth muscle phenotype. Circ Res. 2000;87:355-362.
    • (2000) Circ Res. , vol.87 , pp. 355-362
    • Miano, J.M.1    Berk, B.C.2
  • 13
    • 27944445459 scopus 로고    scopus 로고
    • Myocardin enhances Smad3-mediated transforming growth factor-beta1 signaling in a CArG box-independent manner: Smad-binding element is an important cis element for SM22alpha transcription in vivo
    • Qiu P, Ritchie RP, Fu Z, Cao D, Cumming J, Miano JM, Wang DZ, Li HJ, Li L. Myocardin enhances Smad3-mediated transforming growth factor-beta1 signaling in a CArG box-independent manner: Smad-binding element is an important cis element for SM22alpha transcription in vivo. Circ Res. 2005;97:983-991.
    • (2005) Circ Res. , vol.97 , pp. 983-991
    • Qiu, P.1    Ritchie, R.P.2    Fu, Z.3    Cao, D.4    Cumming, J.5    Miano, J.M.6    Wang, D.Z.7    Li, H.J.8    Li, L.9
  • 14
    • 43149108372 scopus 로고    scopus 로고
    • Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation
    • Shang Y, Yoshida T, Amendt BA, Martin JF, Owens GK. Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation. J Cell Biol. 2008;181:461-473.
    • (2008) J Cell Biol. , vol.181 , pp. 461-473
    • Shang, Y.1    Yoshida, T.2    Amendt, B.A.3    Martin, J.F.4    Owens, G.K.5
  • 15
  • 16
    • 84866307430 scopus 로고    scopus 로고
    • Molecular pathways of notch signaling in vascular smooth muscle cells
    • Boucher J, Gridley T, Liaw L. Molecular pathways of notch signaling in vascular smooth muscle cells. Front Physiol. 2012;3:81.
    • (2012) Front Physiol. , vol.3 , pp. 81
    • Boucher, J.1    Gridley, T.2    Liaw, L.3
  • 17
    • 0024206625 scopus 로고
    • Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element
    • Norman C, Runswick M, Pollock R, Treisman R. Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element. Cell. 1988;55:989-1003.
    • (1988) Cell. , vol.55 , pp. 989-1003
    • Norman, C.1    Runswick, M.2    Pollock, R.3    Treisman, R.4
  • 18
    • 0037870478 scopus 로고    scopus 로고
    • Serum response factor: Toggling between disparate programs of gene expression
    • Miano JM. Serum response factor: toggling between disparate programs of gene expression. J Mol Cell Cardiol. 2003;35:577-593.
    • (2003) J Mol Cell Cardiol. , vol.35 , pp. 577-593
    • Miano, J.M.1
  • 19
    • 0035967868 scopus 로고    scopus 로고
    • Activation of cardiac gene expression by myo-cardin, a transcriptional cofactor for serum response factor
    • Wang D, Chang PS, Wang Z, Sutherland L, Richardson JA, Small E, Krieg PA, Olson EN. Activation of cardiac gene expression by myo-cardin, a transcriptional cofactor for serum response factor. Cell. 2001;105:851-862.
    • (2001) Cell. , vol.105 , pp. 851-862
    • Wang, D.1    Chang, P.S.2    Wang, Z.3    Sutherland, L.4    Richardson, J.A.5    Small, E.6    Krieg, P.A.7    Olson, E.N.8
  • 20
    • 0036773632 scopus 로고    scopus 로고
    • Myocardin: A component of a molecular switch for smooth muscle differentiation
    • Chen J, Kitchen CM, Streb JW, Miano JM. Myocardin: a component of a molecular switch for smooth muscle differentiation. J Mol Cell Cardiol. 2002;34:1345-1356.
    • (2002) J Mol Cell Cardiol. , vol.34 , pp. 1345-1356
    • Chen, J.1    Kitchen, C.M.2    Streb, J.W.3    Miano, J.M.4
  • 21
    • 0037379178 scopus 로고    scopus 로고
    • Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation
    • Du KL, Ip HS, Li J, Chen M, Dandre F, Yu W, Lu MM, Owens GK, Parmacek MS. Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation. Mol Cell Biol. 2003;23:2425-2437.
    • (2003) Mol Cell Biol. , vol.23 , pp. 2425-2437
    • Du, K.L.1    Ip, H.S.2    Li, J.3    Chen, M.4    Dandre, F.5    Yu, W.6    Lu, M.M.7    Owens, G.K.8    Parmacek, M.S.9
  • 23
    • 80052282066 scopus 로고    scopus 로고
    • Synergistic activation of cardiac genes by myocardin and Tbx5
    • Wang C, Cao D, Wang Q, Wang DZ. Synergistic activation of cardiac genes by myocardin and Tbx5. PLoS ONE. 2011;6:e24242.
    • (2011) PLoS ONE. , vol.6
    • Wang, C.1    Cao, D.2    Wang, Q.3    Wang, D.Z.4
  • 24
    • 0041422285 scopus 로고    scopus 로고
    • The serum response factor coactivator myocardin is required for vascular smooth muscle development
    • Li S, Wang DZ, Wang Z, Richardson JA, Olson EN. The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proc Natl Acad Sci USA. 2003;100:9366-9370.
    • (2003) Proc Natl Acad Sci USA. , vol.100 , pp. 9366-9370
    • Li, S.1    Wang, D.Z.2    Wang, Z.3    Richardson, J.A.4    Olson, E.N.5
  • 25
    • 38849110886 scopus 로고    scopus 로고
    • Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice
    • Huang J, Cheng L, Li J, Chen M, Zhou D, Lu MM, Proweller A, Epstein JA, Parmacek MS. Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice. J Clin Invest. 2008;118:515-525.
    • (2008) J Clin Invest. , vol.118 , pp. 515-525
    • Huang, J.1    Cheng, L.2    Li, J.3    Chen, M.4    Zhou, D.5    Lu, M.M.6    Proweller, A.7    Epstein, J.A.8    Parmacek, M.S.9
  • 28
    • 85047690167 scopus 로고    scopus 로고
    • 5' CArG degeneracy in smooth muscle alpha-actin is required for injury-induced gene suppression in vivo
    • Hendrix JA, Wamhoff BR, McDonald OG, Sinha S, Yoshida T, Owens GK. 5' CArG degeneracy in smooth muscle alpha-actin is required for injury-induced gene suppression in vivo. J Clin Invest. 2005;115:418-427.
    • (2005) J Clin Invest. , vol.115 , pp. 418-427
    • Hendrix, J.A.1    Wamhoff, B.R.2    McDonald, O.G.3    Sinha, S.4    Yoshida, T.5    Owens, G.K.6
  • 29
    • 33751191871 scopus 로고    scopus 로고
    • Upregulation of intermediate-conductance Ca2+-activated K+ channel (IKCa1) mediates pheno-typic modulation of coronary smooth muscle
    • Tharp DL, Wamhoff BR, Turk JR, Bowles DK. Upregulation of intermediate-conductance Ca2+-activated K+ channel (IKCa1) mediates pheno-typic modulation of coronary smooth muscle. Am J Physiol Heart Circ Physiol. 2006;291:H2493-H2503.
    • (2006) Am J Physiol Heart Circ Physiol. , vol.291
    • Tharp, D.L.1    Wamhoff, B.R.2    Turk, J.R.3    Bowles, D.K.4
  • 31
    • 37849015440 scopus 로고    scopus 로고
    • RPEL motifs link the serum response factor cofactor MAL but not myocardin to Rho signaling via actin binding
    • Guettler S, Vartiainen MK, Miralles F, Larijani B, Treisman R. RPEL motifs link the serum response factor cofactor MAL but not myocardin to Rho signaling via actin binding. Mol Cell Biol. 2008;28:732-742.
    • (2008) Mol Cell Biol. , vol.28 , pp. 732-742
    • Guettler, S.1    Vartiainen, M.K.2    Miralles, F.3    Larijani, B.4    Treisman, R.5
  • 32
    • 0038737042 scopus 로고    scopus 로고
    • Actin dynamics control SRF activity by regulation of its coactivator MAL
    • Miralles F, Posern G, Zaromytidou AI, Treisman R. Actin dynamics control SRF activity by regulation of its coactivator MAL. Cell. 2003;113:329-342.
    • (2003) Cell. , vol.113 , pp. 329-342
    • Miralles, F.1    Posern, G.2    Zaromytidou, A.I.3    Treisman, R.4
  • 33
    • 77951582061 scopus 로고    scopus 로고
    • Linking actin dynamics and gene transcription to drive cellular motile functions
    • Olson EN, Nordheim A. Linking actin dynamics and gene transcription to drive cellular motile functions. Nat Rev Mol Cell Biol. 2010; 11:353-365.
    • (2010) Nat Rev Mol Cell Biol. , vol.11 , pp. 353-365
    • Olson, E.N.1    Nordheim, A.2
  • 34
    • 0035808389 scopus 로고    scopus 로고
    • Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization
    • Mack CP, Somlyo AV, Hautmann M, Somlyo AP, Owens GK. Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization. J Biol Chem. 2001;276:341-347.
    • (2001) J Biol Chem. , vol.276 , pp. 341-347
    • MacK, C.P.1    Somlyo, A.V.2    Hautmann, M.3    Somlyo, A.P.4    Owens, G.K.5
  • 35
    • 33846991973 scopus 로고    scopus 로고
    • Smooth muscle cell-specifc transcription is regulated by nuclear localization of the myocardin-related transcription factors
    • Hinson JS, Medlin MD, Lockman K, Taylor JM, Mack CP. Smooth muscle cell-specifc transcription is regulated by nuclear localization of the myocardin-related transcription factors. Am J Physiol Heart Circ Physiol. 2007;292:H1170-H1180.
    • (2007) Am J Physiol Heart Circ Physiol. , vol.292
    • Hinson, J.S.1    Medlin, M.D.2    Lockman, K.3    Taylor, J.M.4    MacK, C.P.5
  • 36
    • 37549065952 scopus 로고    scopus 로고
    • Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors
    • Lagna G, Ku MM, Nguyen PH, Neuman NA, Davis BN, Hata A. Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors. J Biol Chem. 2007;282:37244-37255.
    • (2007) J Biol Chem. , vol.282 , pp. 37244-37255
    • Lagna, G.1    Ku, M.M.2    Nguyen, P.H.3    Neuman, N.A.4    Davis, B.N.5    Hata, A.6
  • 37
    • 5644293131 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors
    • Lockman K, Hinson JS, Medlin MD, Morris D, Taylor JM, Mack CP. Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors. J Biol Chem. 2004;279:42422-42430.
    • (2004) J Biol Chem. , vol.279 , pp. 42422-42430
    • Lockman, K.1    Hinson, J.S.2    Medlin, M.D.3    Morris, D.4    Taylor, J.M.5    MacK, C.P.6
  • 38
    • 53249101816 scopus 로고    scopus 로고
    • A Rho kinase/myocardin-related transcription factor-A-dependent mechanism underlies the sphingosylphosphorylcholine-induced differentiation of mes-enchymal stem cells into contractile smooth muscle cells
    • Jeon ES, Park WS, Lee MJ, Kim YM, Han J, Kim JH. A Rho kinase/myocardin-related transcription factor-A-dependent mechanism underlies the sphingosylphosphorylcholine-induced differentiation of mes-enchymal stem cells into contractile smooth muscle cells. Circ Res. 2008;103:635-642.
    • (2008) Circ Res. , vol.103 , pp. 635-642
    • Jeon, E.S.1    Park, W.S.2    Lee, M.J.3    Kim, Y.M.4    Han, J.5    Kim, J.H.6
  • 39
    • 0024344957 scopus 로고
    • Modulation of actin mRNAs in cultured vascular cells by matrix components and TGF-beta 1
    • Kocher O, Madri JA. Modulation of actin mRNAs in cultured vascular cells by matrix components and TGF-beta 1. In Vitro Cell Dev Biol. 1989;25:424-434.
    • (1989) Vitro Cell Dev Biol. , vol.25 , pp. 424-434
    • Kocher, O.1    Madri, J.A.2
  • 40
    • 0025773216 scopus 로고
    • Effects of transforming growth factor-beta 1 on human arterial smooth muscle cells in vitro
    • Björkerud S. Effects of transforming growth factor-beta 1 on human arterial smooth muscle cells in vitro. Arterioscler Thromb. 1991;11: 892-902.
    • (1991) Arterioscler Thromb. , vol.11 , pp. 892-902
    • Björkerud, S.1
  • 41
    • 0032482202 scopus 로고    scopus 로고
    • And hetero-typic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate
    • Hirschi KK, Rohovsky SA, D'Amore PA. PDGF, TGF-beta, and hetero-typic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate. J Cell Biol. 1998;141:805-814.
    • (1998) J Cell Biol. , vol.141 , pp. 805-814
    • Hirschi, K.K.1    Rohovsky, S.A.2    D'Amore, P.A.3    Tgf-Beta, P.4
  • 42
    • 0029897371 scopus 로고    scopus 로고
    • Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members
    • Shah NM, Groves AK, Anderson DJ. Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members. Cell. 1996;85:331-343.
    • (1996) Cell. , vol.85 , pp. 331-343
    • Shah, N.M.1    Groves, A.K.2    Anderson, D.J.3
  • 43
    • 0031730268 scopus 로고    scopus 로고
    • Transforming growth factor-beta dynamically regulates vascular smooth muscle differentiation in vivo
    • Grainger DJ, Metcalfe JC, Grace AA, Mosedale DE. Transforming growth factor-beta dynamically regulates vascular smooth muscle differentiation in vivo. J Cell Sci. 1998;111 (Pt 19):2977-2988.
    • (1998) J Cell Sci. , vol.111 , Issue.PART 19 , pp. 2977-2988
    • Grainger, D.J.1    Metcalfe, J.C.2    Grace, A.A.3    Mosedale, D.E.4
  • 44
    • 24744446597 scopus 로고    scopus 로고
    • Transforming growth factor-beta1-induced expression of smooth muscle marker genes involves activation of PKN and p38 MAPK
    • Deaton RA, Su C, Valencia TG, Grant SR. Transforming growth factor-beta1-induced expression of smooth muscle marker genes involves activation of PKN and p38 MAPK. J Biol Chem. 2005;280: 31172-31181.
    • (2005) J Biol Chem. , vol.280 , pp. 31172-31181
    • Deaton, R.A.1    Su, C.2    Valencia, T.G.3    Grant, S.R.4
  • 45
    • 33744959772 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling enhances transdifferen-tiation of macrophages into smooth muscle-like cells
    • Ninomiya K, Takahashi A, Fujioka Y, Ishikawa Y, Yokoyama M. Transforming growth factor-beta signaling enhances transdifferen-tiation of macrophages into smooth muscle-like cells. Hypertens Res. 2006;29:269-276.
    • (2006) Hypertens Res. , vol.29 , pp. 269-276
    • Ninomiya, K.1    Takahashi, A.2    Fujioka, Y.3    Ishikawa, Y.4    Yokoyama, M.5
  • 46
    • 38349113170 scopus 로고    scopus 로고
    • Transforming growth factor-beta (TGF-1) down-regulates Notch3 in fbroblasts to promote smooth muscle gene expression
    • Kennard S, Liu H, Lilly B. Transforming growth factor-beta (TGF-1) down-regulates Notch3 in fbroblasts to promote smooth muscle gene expression. J Biol Chem. 2008;283:1324-1333.
    • (2008) J Biol Chem. , vol.283 , pp. 1324-1333
    • Kennard, S.1    Liu, H.2    Lilly, B.3
  • 47
    • 81155159182 scopus 로고    scopus 로고
    • Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells
    • Tang Y, Yang X, Friesel RE, Vary CP, Liaw L. Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells. J Vasc Res. 2011;48:485-494.
    • (2011) J Vasc Res. , vol.48 , pp. 485-494
    • Tang, Y.1    Yang, X.2    Friesel, R.E.3    Vary, C.P.4    Liaw, L.5
  • 48
    • 77952941222 scopus 로고    scopus 로고
    • Krüppel-like factor 4 promotes differentiation by transforming growth factor-beta receptor-mediated Smad and p38 MAPK signaling in vascular smooth muscle cells
    • Li HX, Han M, Bernier M, Zheng B, Sun SG, Su M, Zhang R, Fu JR, Wen JK. Krüppel-like factor 4 promotes differentiation by transforming growth factor-beta receptor-mediated Smad and p38 MAPK signaling in vascular smooth muscle cells. J Biol Chem. 2010;285:17846-17856.
    • (2010) J Biol Chem. , vol.285 , pp. 17846-17856
    • Li, H.X.1    Han, M.2    Bernier, M.3    Zheng, B.4    Sun, S.G.5    Su, M.6    Zhang, R.7    Fu, J.R.8    Wen, J.K.9
  • 51
    • 80051944105 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 (TGF-beta1) utilizes distinct pathways for the transcriptional activation of microRNA 143/145 in human coronary artery smooth muscle cells
    • Long X, Miano JM. Transforming growth factor-beta1 (TGF-beta1) utilizes distinct pathways for the transcriptional activation of microRNA 143/145 in human coronary artery smooth muscle cells. J Biol Chem. 2011;286:30119-30129.
    • (2011) J Biol Chem. , vol.286 , pp. 30119-30129
    • Long, X.1    Miano, J.M.2
  • 52
    • 34547154349 scopus 로고    scopus 로고
    • P38 MAP-kinases pathway regulation, function and role in human diseases
    • Cuenda A, Rousseau S. p38 MAP-kinases pathway regulation, function and role in human diseases. Biochim Biophys Acta. 2007;1773:1358-1375.
    • (2007) Biochim Biophys Acta. , vol.1773 , pp. 1358-1375
    • Cuenda, A.1    Rousseau, S.2
  • 53
    • 0031455727 scopus 로고    scopus 로고
    • Remodeling with neointima formation in the mouse carotid artery after cessation of blood fow
    • Kumar A, Lindner V. Remodeling with neointima formation in the mouse carotid artery after cessation of blood fow. Arterioscler Thromb Vasc Biol. 1997;17:2238-2244.
    • (1997) Arterioscler Thromb Vasc Biol. , vol.17 , pp. 2238-2244
    • Kumar, A.1    Lindner, V.2
  • 54
    • 0346122781 scopus 로고    scopus 로고
    • Flow-induced vascular remodeling in the mouse: A model for carotid intima-media thickening
    • Korshunov VA, Berk BC. Flow-induced vascular remodeling in the mouse: a model for carotid intima-media thickening. Arterioscler Thromb Vasc Biol. 2003;23:2185-2191.
    • (2003) Arterioscler Thromb Vasc Biol. , vol.23 , pp. 2185-2191
    • Korshunov, V.A.1    Berk, B.C.2
  • 55
    • 84856078064 scopus 로고    scopus 로고
    • Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cells
    • Nanda V, Miano JM. Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cells. J Biol Chem. 2012;287:2459-2467.
    • (2012) J Biol Chem. , vol.287 , pp. 2459-2467
    • Nanda, V.1    Miano, J.M.2
  • 56
    • 33745152386 scopus 로고    scopus 로고
    • The myocardin family of transcrip-tional coactivators: Versatile regulators of cell growth, migration, and myogenesis
    • Pipes GC, Creemers EE, Olson EN. The myocardin family of transcrip-tional coactivators: versatile regulators of cell growth, migration, and myogenesis. Genes Dev. 2006;20:1545-1556.
    • (2006) Genes Dev. , vol.20 , pp. 1545-1556
    • Pipes, G.C.1    Creemers, E.E.2    Olson, E.N.3
  • 58
    • 0027967951 scopus 로고
    • Smooth muscle myosin heavy chain exclusively marks the smooth muscle lineage during mouse embryogenesis
    • Miano JM, Cserjesi P, Ligon KL, Periasamy M, Olson EN. Smooth muscle myosin heavy chain exclusively marks the smooth muscle lineage during mouse embryogenesis. Circ Res. 1994;75:803-812.
    • (1994) Circ Res. , vol.75 , pp. 803-812
    • Miano, J.M.1    Cserjesi, P.2    Ligon, K.L.3    Periasamy, M.4    Olson, E.N.5
  • 59
    • 0037155202 scopus 로고    scopus 로고
    • Transforming growth factor-beta induction of smooth muscle cell phe-notpye requires transcriptional and post-transcriptional control of serum response factor
    • Hirschi KK, Lai L, Belaguli NS, Dean DA, Schwartz RJ, Zimmer WE. Transforming growth factor-beta induction of smooth muscle cell phe-notpye requires transcriptional and post-transcriptional control of serum response factor. J Biol Chem. 2002;277:6287-6295.
    • (2002) J Biol Chem. , vol.277 , pp. 6287-6295
    • Hirschi, K.K.1    Lai, L.2    Belaguli, N.S.3    Dean, D.A.4    Schwartz, R.J.5    Zimmer, W.E.6
  • 60
    • 79955379849 scopus 로고    scopus 로고
    • Smad3-mediated myo-cardin silencing: A novel mechanism governing the initiation of smooth muscle differentiation
    • Xie WB, Li Z, Miano JM, Long X, Chen SY. Smad3-mediated myo-cardin silencing: a novel mechanism governing the initiation of smooth muscle differentiation. J Biol Chem. 2011;286:15050-15057.
    • (2011) J Biol Chem. , vol.286 , pp. 15050-15057
    • Xie, W.B.1    Li, Z.2    Miano, J.M.3    Long, X.4    Chen, S.Y.5
  • 61
    • 80051532504 scopus 로고    scopus 로고
    • Down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphoge-netic protein 4
    • Davis-Dusenbery BN, Chan MC, Reno KE, Weisman AS, Layne MD, Lagna G, Hata A. down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphoge-netic protein 4. J Biol Chem. 2011;286:28097-28110.
    • (2011) J Biol Chem. , vol.286 , pp. 28097-28110
    • Davis-Dusenbery, B.N.1    Chan, M.C.2    Reno, K.E.3    Weisman, A.S.4    Layne, M.D.5    Lagna, G.6    Hata, A.7
  • 62
    • 0033577854 scopus 로고    scopus 로고
    • Changes in the balance of phosphoinositide 3-kinase/protein kinase B (Akt) and the mitogen-activated protein kinases (ERK/p38MAPK) determine a phenotype of visceral and vascular smooth muscle cells
    • Hayashi K, Takahashi M, Kimura K, Nishida W, Saga H, Sobue K. Changes in the balance of phosphoinositide 3-kinase/protein kinase B (Akt) and the mitogen-activated protein kinases (ERK/p38MAPK) determine a phenotype of visceral and vascular smooth muscle cells. J Cell Biol. 1999;145:727-740.
    • (1999) J Cell Biol. , vol.145 , pp. 727-740
    • Hayashi, K.1    Takahashi, M.2    Kimura, K.3    Nishida, W.4    Saga, H.5    Sobue, K.6
  • 64
    • 0036714017 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-beta signaling by low molecular weight compounds interfering with ATP-or substrate-binding sites of the TGF beta type i receptor kinase
    • Yakymovych I, Engström U, Grimsby S, Heldin CH, Souchelnytskyi S. Inhibition of transforming growth factor-beta signaling by low molecular weight compounds interfering with ATP-or substrate-binding sites of the TGF beta type I receptor kinase. Biochemistry. 2002;41:11000-11007.
    • (2002) Biochemistry. , vol.41 , pp. 11000-11007
    • Yakymovych, I.1    Engström, U.2    Grimsby, S.3    Heldin, C.H.4    Souchelnytskyi, S.5
  • 65
    • 13244262989 scopus 로고    scopus 로고
    • Fluvastatin prevents vascular hyperplasia by inhibiting phenotype modulation and proliferation through extracellular signal-regulated kinase 1 and 2 and p38 mitogen-activated protein kinase inactivation in organ-cultured artery
    • Sakamoto K, Murata T, Chuma H, Hori M, Ozaki H. Fluvastatin prevents vascular hyperplasia by inhibiting phenotype modulation and proliferation through extracellular signal-regulated kinase 1 and 2 and p38 mitogen-activated protein kinase inactivation in organ-cultured artery. Arterioscler Thromb Vasc Biol. 2005;25:327-333.
    • (2005) Arterioscler Thromb Vasc Biol. , vol.25 , pp. 327-333
    • Sakamoto, K.1    Murata, T.2    Chuma, H.3    Hori, M.4    Ozaki, H.5
  • 66
    • 31944442346 scopus 로고    scopus 로고
    • A role for p38 mitogen-activated protein kinase and c-myc in endothelin-dependent rat aortic smooth muscle cell proliferation
    • Chen S, Qiong Y, Gardner DG. A role for p38 mitogen-activated protein kinase and c-myc in endothelin-dependent rat aortic smooth muscle cell proliferation. Hypertension. 2006;47:252-258.
    • (2006) Hypertension. , vol.47 , pp. 252-258
    • Chen, S.1    Qiong, Y.2    Gardner, D.G.3
  • 67
    • 50349083898 scopus 로고    scopus 로고
    • Requirement for p38 mitogen-activated protein kinase activity in neointima formation after vascular injury
    • Proctor BM, Jin X, Lupu TS, Muglia LJ, Semenkovich CF, Muslin AJ. Requirement for p38 mitogen-activated protein kinase activity in neointima formation after vascular injury. Circulation. 2008;118:658-666.
    • (2008) Circulation. , vol.118 , pp. 658-666
    • Proctor, B.M.1    Jin, X.2    Lupu, T.S.3    Muglia, L.J.4    Semenkovich, C.F.5    Muslin, A.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.