A rho kinase/myocardin-related transcription factor-a-dependent mechanism underlies the sphingosylphosphorylcholine-induced differentiation of mesenchymal stem cells into contractile smooth muscle cells

Circulation Research

Volumn 103, Issue 6, 2008, Pages 635-642

  Jeon, Eun Su ^a   Park, Won Sun ^b   Lee, Mi Jeong ^a   Kim, Young Mi ^a   Han, Jin ^b   Kim, Jae Ho ^a,c  

^a National University   (South Korea)

^b Inje University   (South Korea)

^c Pusan National University School of Medicine   (South Korea)

Author keywords

Differentiation; Mesenchymal stem cells; Rho kinase; Smooth muscle; Sphingosylphosphorylcholine

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CALCIUM CHANNEL; CALCIUM CHANNEL L TYPE; CARBACHOL; COLLAGEN GEL; IBERIOTOXIN; ION CHANNEL; MYOCARDIN; MYOCARDIN RELATED TRANSCRIPTION FACTOR A; NIFEDIPINE; POTASSIUM CHANNEL; POTASSIUM CHLORIDE; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SPHINGOSYLPHOSPHORYLCHOLINE; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; DRUG DERIVATIVE; MKL1 PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; PHOSPHORYLCHOLINE; SPHINGOSINE; SPHINGOSINE PHOSPHORYLCHOLINE; TRANSACTIVATOR PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CONDUCTANCE; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MEMBRANE DEPOLARIZATION; MESENCHYMAL STEM CELL; MICROSCOPY; MOLECULAR MECHANICS; MUSCLE CONTRACTILITY; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE FIBER; WESTERN BLOTTING; WHOLE CELL; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; ENZYMOLOGY; GENETICS; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY;

CELL DIFFERENTIATION; CELLS, CULTURED; DNA-BINDING PROTEINS; HUMANS; MESENCHYMAL STEM CELLS; MUSCLE CONTRACTION; MYOCYTES, SMOOTH MUSCLE; NUCLEAR PROTEINS; ONCOGENE PROTEINS, FUSION; PHOSPHORYLCHOLINE; RHO-ASSOCIATED KINASES; SPHINGOSINE; TRANS-ACTIVATORS;

EID: 53249101816     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.180885     Document Type: Article

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