Variation in the TLR10/TLR1/TLR6 locus is the major genetic determinant of interindividual difference in TLR1/2-mediated responses

Genes and Immunity

Volumn 14, Issue 1, 2013, Pages 52-57

  Mikacenic, C ^a   Reiner, A P ^a   Holden, T D ^a   Nickerson, D A ^a   Wurfel, M M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

genomics; innate immunity; polymorphism; TLR

Indexed keywords

BACTERIAL PROTEIN; GENOMIC DNA; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 6;

ADULT; AMINO ACID ANALYSIS; ARTICLE; BLOOD SAMPLING; CYTOKINE PRODUCTION; EX VIVO STUDY; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; CHROMOSOMES, HUMAN, PAIR 4; CYTOKINES; FEMALE; GENES, DOMINANT; GENOME-WIDE ASSOCIATION STUDY; HUMANS; IMMUNITY, INNATE; LIPOPEPTIDES; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, GENETIC; TOLL-LIKE RECEPTOR 1; TOLL-LIKE RECEPTOR 10; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 6; TOLL-LIKE RECEPTORS;

BACTERIA (MICROORGANISMS);

EID: 84872896393     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2012.53     Document Type: Article

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