Immunogenic peptides can be detected in whole gluten by transamidating highly susceptible glutamine residues: Implication in the search for gluten-free cereals

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 3, 2013, Pages 747-754

  Mamone, Gianfranco ^a   Camarca, Alessandra ^a,b   Fierro, Olga ^a   Sidney, John ^c   Mazzarella, Giuseppe ^a   Addeo, Francesco ^b   Auricchio, Salvatore ^b   Troncone, Riccardo ^b   Sette, Alessandro ^c   Gianfrani, Carmen ^a,b  

^a CNR   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

celiac disease; cereals; gluten epitopes; tissue transglutaminase

Indexed keywords

CELIAC DISEASE; CEREALS; GLUTEN EPITOPES; GLUTEN PEPTIDES; GLUTEN-FREE; IMMUNE ACTIVATION; IMMUNOGENICITY; INTESTINAL MUCOSA; MONODANSYLCADAVERINE; NANOSPRAY; PROTEIN EXTRACT; T CELLS; TANDEM MASS SPECTROMETRY; TISSUE TRANSGLUTAMINASE;

AMINO ACIDS; ANTIGENS; CELL CULTURE; CELL PROLIFERATION; MASS SPECTROMETRY; POLYPEPTIDES;

PEPTIDES;

EPITOPE; GLIADIN; GLUTAMINE; GLUTEN; GUANINE NUCLEOTIDE BINDING PROTEIN; PEPTIDE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2;

ADOLESCENT; ADULT; ANTIBODY PRODUCTION; ARTICLE; CELIAC DISEASE; CELL LINE; CHEMISTRY; GENETICS; HUMAN; IMMUNOLOGY; INTESTINE MUCOSA; MIDDLE AGED; T LYMPHOCYTE; TANDEM MASS SPECTROMETRY; WHEAT; YOUNG ADULT;

ADOLESCENT; ADULT; ANTIBODY FORMATION; CELIAC DISEASE; CELL LINE; EPITOPES, T-LYMPHOCYTE; GLIADIN; GLUTAMINE; GLUTENS; GTP-BINDING PROTEINS; HUMANS; INTESTINAL MUCOSA; MIDDLE AGED; PEPTIDES; T-LYMPHOCYTES; TANDEM MASS SPECTROMETRY; TRANSGLUTAMINASES; TRITICUM; YOUNG ADULT;

TRITICUM AESTIVUM;

EID: 84872868221     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf3040435     Document Type: Article

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