The preferred substrates for transglutaminase 2 in a complex wheat gluten digest are peptide fragments harboring celiac disease T-cell epitopes

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  DØrum, Siri ^a   Arntzen, Magnus Ø ^a,b,c   Qiao, Shuo Wang ^a   Holm, Anders ^b   Koehler, Christian J ^a   Thiede, Bernd ^a   Sollid, Ludvig M ^a,b   Fleckenstein, Burkhard ^a,b  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLUTEN; HLA DQ ANTIGEN; PEPTIDE FRAGMENT; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; GLIADIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PEPTIDE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; RECOMBINANT PROTEIN;

ANTIGEN FUNCTION; ANTIGEN RECOGNITION; ANTIGEN SELECTION; ARTICLE; CELIAC DISEASE; CELLULAR IMMUNITY; CONTROLLED STUDY; DATA BASE; ENZYME SUBSTRATE; INFORMATION RETRIEVAL; LIQUID CHROMATOGRAPHY; PEPTIDE ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN ISOLATION; TANDEM MASS SPECTROMETRY; AMINO ACID SEQUENCE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; HUMAN; IMMUNOLOGY; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; NANOTECHNOLOGY; SYNTHESIS; WHEAT;

TRITICUM AESTIVUM;

AMINO ACID SEQUENCE; CELIAC DISEASE; CHROMATOGRAPHY, LIQUID; EPITOPES, T-LYMPHOCYTE; GLIADIN; GLUTENS; GTP-BINDING PROTEINS; HUMANS; MASS SPECTROMETRY; NANOTECHNOLOGY; PEPTIDE FRAGMENTS; PEPTIDES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TRANSGLUTAMINASES; TRITICUM;

EID: 78649512556     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014056     Document Type: Article

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