Changing single side-chains can greatly enhance the resistance of a membrane protein to irreversible inactivation

Journal of Molecular Biology

Volumn 290, Issue 2, 1999, Pages 559-564

  Lau, Francis W ^a   Nauli, Sehat ^a   Zhou, Yufeng ^a   Bowie, James U ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cysteine scanning mutagenesis; Diacylglycerol kinase; Protein denaturation; Protein engineering; Protein stability

Indexed keywords

CYSTEINE; DETERGENT; DIACYLGLYCEROL KINASE; MEMBRANE PROTEIN; MUTANT PROTEIN;

ARTICLE; ENZYME INACTIVATION; HALF LIFE TIME; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN STRUCTURE; THERMOSTABILITY;

NEGIBACTERIA;

EID: 0033538418     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.2905     Document Type: Article

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