메뉴 건너뛰기




Volumn 29, Issue 8, 2012, Pages 957-969

Over-expression of integrin-linked kinase correlates with aberrant expression of Snail, E-cadherin and N-cadherin in oral squamous cell carcinoma: Implications in tumor progression and metastasis

Author keywords

Epithelial mesenchymal transition; Integrin linked kinase; Metastasis; Oral squamous cell carcinoma; Progression; Snail

Indexed keywords

INTEGRIN LINKED KINASE; NERVE CELL ADHESION MOLECULE; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; CADHERIN; INTEGRIN-LINKED KINASE; PROTEIN SERINE THREONINE KINASE; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

EID: 84872859966     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-012-9485-1     Document Type: Article
Times cited : (53)

References (37)
  • 1
    • 31144467334 scopus 로고    scopus 로고
    • Oral medicine-update for the dental practitioner oral cancer
    • 16415822 10.1038/sj.bdj.4813117 1:STN:280:DC%2BD28%2FisFemsQ%3D%3D
    • Scully C, Felix DH (2006) Oral medicine-update for the dental practitioner oral cancer. Br Dent J 200:13-17
    • (2006) Br Dent J , vol.200 , pp. 13-17
    • Scully, C.1    Felix, D.H.2
  • 2
    • 24644480749 scopus 로고    scopus 로고
    • Molecular requirements for epithelial-mesenchymal transition during tumor progression
    • 16098727 10.1016/j.ceb.2005.08.001 1:CAS:528:DC%2BD2MXhtVWnsb7L
    • Huber MA, Kraut N, Beug H (2005) Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol 17:548-558
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 548-558
    • Huber, M.A.1    Kraut, N.2    Beug, H.3
  • 3
    • 33749024777 scopus 로고    scopus 로고
    • Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis
    • 16951136 10.1158/0008-5472.CAN-06-0410 1:CAS:528:DC%2BD28XovF2jtb8%3D
    • Christiansen JJ, Rajasekaran AK (2006) Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res 66:8319-8326
    • (2006) Cancer Res , vol.66 , pp. 8319-8326
    • Christiansen, J.J.1    Rajasekaran, A.K.2
  • 4
    • 22144461325 scopus 로고    scopus 로고
    • Transforming growth factor-β signaling during epithelial-mesenchymal transformation: Implications for embryogenesis and tumor metastasis
    • 15942189 10.1159/000084505 1:CAS:528:DC%2BD2MXkvVOnsr8%3D
    • Nawshad A, LaGamba D, Polad A et al (2005) Transforming growth factor-β signaling during epithelial-mesenchymal transformation: implications for embryogenesis and tumor metastasis. Cells Tissues Organs 179:11-23
    • (2005) Cells Tissues Organs , vol.179 , pp. 11-23
    • Nawshad, A.1    Lagamba, D.2    Polad, A.3
  • 5
    • 0031962084 scopus 로고    scopus 로고
    • Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity
    • 9417112 10.1074/jbc.273.1.528 1:CAS:528:DyaK1cXjvFCmtw%3D%3D
    • Wu C, Keightley SY, Leung-Hagesteijn C et al (1998) Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity. J Biol Chem 273:528-536
    • (1998) J Biol Chem , vol.273 , pp. 528-536
    • Wu, C.1    Keightley, S.Y.2    Leung-Hagesteijn, C.3
  • 6
    • 0035067120 scopus 로고    scopus 로고
    • Overexpression of the integrin-linked kinase mesenchymally transforms mammary epithelial cells
    • 11228156 1:CAS:528:DC%2BD3MXivVKitb4%3D
    • Somasiri A, Howarth A, Goswami D et al (2001) Overexpression of the integrin-linked kinase mesenchymally transforms mammary epithelial cells. J Cell Sci 114:1125-1136
    • (2001) J Cell Sci , vol.114 , pp. 1125-1136
    • Somasiri, A.1    Howarth, A.2    Goswami, D.3
  • 7
    • 11144225205 scopus 로고    scopus 로고
    • Integrin-linked kinase: A cancer therapeutic target unique among its ILK
    • 15630415 10.1038/nrc1524 1:CAS:528:DC%2BD2MXlvVeh
    • Hannigan G, Troussard AA, Dedhar S (2005) Integrin-linked kinase: a cancer therapeutic target unique among its ILK. Nat Rev Cancer 5:51-63
    • (2005) Nat Rev Cancer , vol.5 , pp. 51-63
    • Hannigan, G.1    Troussard, A.A.2    Dedhar, S.3
  • 8
    • 78651273473 scopus 로고    scopus 로고
    • Expression of integrin-linked kinase in lung squamous cell carcinoma and adenocarcinoma: Correlation with E-cadherin expression, tumor microvessel density and clinical outcome
    • 21136077 10.1007/s00428-010-1016-3 1:CAS:528:DC%2BC3MXjtVaqsw%3D%3D
    • Yu J, Shi R, Zhang D et al (2011) Expression of integrin-linked kinase in lung squamous cell carcinoma and adenocarcinoma: correlation with E-cadherin expression, tumor microvessel density and clinical outcome. Virchows Arch 458:99-107
    • (2011) Virchows Arch , vol.458 , pp. 99-107
    • Yu, J.1    Shi, R.2    Zhang, D.3
  • 9
    • 0141891463 scopus 로고    scopus 로고
    • Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival
    • 14555513 1:CAS:528:DC%2BD3sXotVShsbo%3D
    • Dai DL, Makretsov N, Campos EI et al (2003) Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival. Clin Cancer Res 9:4409-4414
    • (2003) Clin Cancer Res , vol.9 , pp. 4409-4414
    • Dai, D.L.1    Makretsov, N.2    Campos, E.I.3
  • 10
    • 29744446515 scopus 로고    scopus 로고
    • ILK over-expression in human colon cancer progression correlates with activation of β-catenin, down-regulation of E-cadherin and activation of the Akt-FKHR pathway
    • 16278819 10.1002/path.1860 1:CAS:528:DC%2BD28XosVSktA%3D%3D
    • Bravou V, Klironomos G, Papadaki E et al (2006) ILK over-expression in human colon cancer progression correlates with activation of β-catenin, down-regulation of E-cadherin and activation of the Akt-FKHR pathway. J Pathol 208:91-99
    • (2006) J Pathol , vol.208 , pp. 91-99
    • Bravou, V.1    Klironomos, G.2    Papadaki, E.3
  • 11
    • 0037295608 scopus 로고    scopus 로고
    • Expression of integrin-linked kinase is closely correlated with invasion and metastasis of gastric carcinoma
    • 12596061 1:CAS:528:DC%2BD3sXjsFWjs7w%3D
    • Ito R, Oue N, Zhu X et al (2003) Expression of integrin-linked kinase is closely correlated with invasion and metastasis of gastric carcinoma. Virchows Arch 442:118-123
    • (2003) Virchows Arch , vol.442 , pp. 118-123
    • Ito, R.1    Oue, N.2    Zhu, X.3
  • 12
    • 79951803441 scopus 로고    scopus 로고
    • Integrin-linked kinase overexpression and its oncogenic role in promoting tumorigenicity of hepatocellular carcinoma
    • 21347395 10.1371/journal.pone.0016984 1:CAS:528:DC%2BC3MXitlyjtbs%3D
    • Chan J, Ko FC, Yeung YS et al (2011) Integrin-linked kinase overexpression and its oncogenic role in promoting tumorigenicity of hepatocellular carcinoma. PLoS ONE 6:e16984
    • (2011) PLoS ONE , vol.6 , pp. 16984
    • Chan, J.1    Ko, F.C.2    Yeung, Y.S.3
  • 13
    • 82255175153 scopus 로고    scopus 로고
    • The importance of integrin-linked kinase in the regulation of bladder cancer invasion
    • 21351095 10.1002/ijc.26008 1:CAS:528:DC%2BC3MXhsFaru7vM
    • Matsui Y, Assi K, Ogawa O et al (2012) The importance of integrin-linked kinase in the regulation of bladder cancer invasion. Int J Cancer 130:521-531
    • (2012) Int J Cancer , vol.130 , pp. 521-531
    • Matsui, Y.1    Assi, K.2    Ogawa, O.3
  • 14
    • 79954520404 scopus 로고    scopus 로고
    • The mechanism of contribution of integrin linked kinase (ILK) to epithelial-mesenchymal transition (EMT)
    • 21035499 10.1016/j.advenzreg.2010.09.005 1:CAS:528:DC%2BC3MXos1Ojt7k%3D
    • Gil D, Ciołczyk-Wierzbicka D, Dulińska-Litewka J et al (2011) The mechanism of contribution of integrin linked kinase (ILK) to epithelial-mesenchymal transition (EMT). Adv Enzyme Regul 51:195-207
    • (2011) Adv Enzyme Regul , vol.51 , pp. 195-207
    • Gil, D.1    Ciołczyk-Wierzbicka, D.2    Dulińska-Litewka, J.3
  • 15
    • 54549091060 scopus 로고    scopus 로고
    • Integrin-linked kinase regulates E-cadherin expression through PARP-1
    • 18773488 10.1002/dvdy.21685 1:CAS:528:DC%2BD1cXhtlWrtLfE
    • McPhee TR, McDonald PC, Oloumi A et al (2008) Integrin-linked kinase regulates E-cadherin expression through PARP-1. Dev Dyn 237:2737-2747
    • (2008) Dev Dyn , vol.237 , pp. 2737-2747
    • McPhee, T.R.1    McDonald, P.C.2    Oloumi, A.3
  • 16
    • 84861594264 scopus 로고    scopus 로고
    • Cadherin switch from E- to N-cadherin in melanoma progression is regulated by the PI3K/PTEN pathway through twist and Snail
    • 10.1111/j.1365-2133.2012.10824.x 22332917
    • Hao L, Ha JR, Kuzel P et al (2012) Cadherin switch from E- to N-cadherin in melanoma progression is regulated by the PI3K/PTEN pathway through twist and Snail. Br J Dermatol. doi: 10.1111/j.1365-2133.2012.10824.x
    • (2012) Br J Dermatol
    • Hao, L.1    Ha, J.R.2    Kuzel, P.3
  • 17
    • 33846341810 scopus 로고    scopus 로고
    • Effects of the integrin-linked kinase inhibitor QLT0267 on squamous cell carcinoma of the head and neck
    • 17224516 10.1001/archotol.133.1.15
    • Younes MN, Yigitbasi OG, Yazici YD et al (2007) Effects of the integrin-linked kinase inhibitor QLT0267 on squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 133:15-23
    • (2007) Arch Otolaryngol Head Neck Surg , vol.133 , pp. 15-23
    • Younes, M.N.1    Yigitbasi, O.G.2    Yazici, Y.D.3
  • 19
    • 0026568566 scopus 로고
    • Malignancy grading of the deep invasive margins of oral squamous cell carcinomas has high prognostic value
    • 1517891 10.1002/path.1711660409 1:STN:280:DyaK38zovFWjsQ%3D%3D
    • Bryne M, Koppang HS, Lilleng R et al (1992) Malignancy grading of the deep invasive margins of oral squamous cell carcinomas has high prognostic value. J Pathol 166:375-381
    • (1992) J Pathol , vol.166 , pp. 375-381
    • Bryne, M.1    Koppang, H.S.2    Lilleng, R.3
  • 20
    • 53549115923 scopus 로고    scopus 로고
    • Intratumoral lymphangiogenesis in oral squamous cell carcinoma and its clinicopathological significance
    • 19012622 10.1111/j.1600-0714.2008.00707.x 1:STN:280: DC%2BD1cjksVGktg%3D%3D
    • Zhao D, Pan J, Li XQ et al (2008) Intratumoral lymphangiogenesis in oral squamous cell carcinoma and its clinicopathological significance. J Oral Pathol Med 37:616-625
    • (2008) J Oral Pathol Med , vol.37 , pp. 616-625
    • Zhao, D.1    Pan, J.2    Li, X.Q.3
  • 21
    • 80053203964 scopus 로고    scopus 로고
    • Intratumoral c-Met expression is associated with vascular endothelial growth factor C expression, lymphangiogenesis, and lymph node metastasis in oral squamous cell carcinoma: Implications for use as a prognostic marker
    • 21531000 10.1016/j.humpath.2010.03.012 1:CAS:528:DC%2BC3MXht1ensrbK
    • Zhao D, Wang SH, Feng Y et al (2011) Intratumoral c-Met expression is associated with vascular endothelial growth factor C expression, lymphangiogenesis, and lymph node metastasis in oral squamous cell carcinoma: implications for use as a prognostic marker. Hum Pathol 42:1514-1523
    • (2011) Hum Pathol , vol.42 , pp. 1514-1523
    • Zhao, D.1    Wang, S.H.2    Feng, Y.3
  • 22
    • 77951707634 scopus 로고    scopus 로고
    • ILK expression in human basal cell carcinoma correlates with epithelial-mesenchymal transition markers and tumour invasion
    • 20546345 10.1111/j.1365-2559.2010.03556.x
    • Papanikolaou S, Bravou V, Gyftopoulos K et al (2010) ILK expression in human basal cell carcinoma correlates with epithelial-mesenchymal transition markers and tumour invasion. Histopathology 56:799-809
    • (2010) Histopathology , vol.56 , pp. 799-809
    • Papanikolaou, S.1    Bravou, V.2    Gyftopoulos, K.3
  • 23
    • 38149007268 scopus 로고    scopus 로고
    • Molecular pathogenesis of oral squamous cell carcinoma: Implications for therapy
    • 10.1177/154405910808700217 1:CAS:528:DC%2BC3cXotFartbg%3D
    • Choi S, Myers JN (2008) Molecular pathogenesis of oral squamous cell carcinoma: implications for therapy. J Dent Res 87:191
    • (2008) J Dent Res , vol.87 , pp. 191
    • Choi, S.1    Myers, J.N.2
  • 24
    • 34347336432 scopus 로고    scopus 로고
    • The role of epithelial-mesenchymal transition in oral squamous cell carcinoma and oral submucous fibrosis
    • 17537414 10.1016/j.cca.2007.04.014
    • Yanjia H, Xinchun J (2007) The role of epithelial-mesenchymal transition in oral squamous cell carcinoma and oral submucous fibrosis. Clin Chim Acta 383:51-56
    • (2007) Clin Chim Acta , vol.383 , pp. 51-56
    • Yanjia, H.1    Xinchun, J.2
  • 25
    • 77956533018 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in oral squamous cell carcinoma triggered by transforming growth factor-beta1 is Snail family-dependent and correlates with matrix metalloproteinase-2 and -9 expressions
    • 20664935 1:CAS:528:DC%2BC3cXhtFSkt73K
    • Qiao B, Johnson NW, Gao J (2010) Epithelial-mesenchymal transition in oral squamous cell carcinoma triggered by transforming growth factor-beta1 is Snail family-dependent and correlates with matrix metalloproteinase-2 and -9 expressions. Int J Oncol 37:663-668
    • (2010) Int J Oncol , vol.37 , pp. 663-668
    • Qiao, B.1    Johnson, N.W.2    Gao, J.3
  • 26
    • 42449134408 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition in head and neck squamous carcinoma: Association of Src activation with E-cadherin down-regulation, vimentin expression, and aggressive tumor features
    • 18327819 10.1002/cncr.23410 1:CAS:528:DC%2BD1cXmtFOlu7k%3D
    • Mandal M, Myers JN, Lippman SM et al (2008) Epithelial to mesenchymal transition in head and neck squamous carcinoma: association of Src activation with E-cadherin down-regulation, vimentin expression, and aggressive tumor features. Cancer 112:2088-2100
    • (2008) Cancer , vol.112 , pp. 2088-2100
    • Mandal, M.1    Myers, J.N.2    Lippman, S.M.3
  • 27
    • 0042978472 scopus 로고    scopus 로고
    • Expression of E-cadherin, alpha-catenin, and beta-catenin in the process of lymph node metastasis in oral squamous cell carcinoma
    • 12888830 10.1038/sj.bjc.6601124 1:CAS:528:DC%2BD3sXlsl2rsLk%3D
    • Tanaka N, Odajima T, Ogi K et al (2003) Expression of E-cadherin, alpha-catenin, and beta-catenin in the process of lymph node metastasis in oral squamous cell carcinoma. Br J Cancer 89:557-563
    • (2003) Br J Cancer , vol.89 , pp. 557-563
    • Tanaka, N.1    Odajima, T.2    Ogi, K.3
  • 28
    • 33847135187 scopus 로고    scopus 로고
    • Expression of E-cadherin, P-cadherin and N-cadherin in oral squamous cell carcinoma: Correlation with the clinicopathologic features and patient outcome
    • 17296306 10.1016/j.jcms.2006.11.004
    • Pyo SW, Hashimoto M, Kim YS et al (2007) Expression of E-cadherin, P-cadherin and N-cadherin in oral squamous cell carcinoma: correlation with the clinicopathologic features and patient outcome. J Craniomaxillofac Surg 35:1-9
    • (2007) J Craniomaxillofac Surg , vol.35 , pp. 1-9
    • Pyo, S.W.1    Hashimoto, M.2    Kim, Y.S.3
  • 29
    • 5444230567 scopus 로고    scopus 로고
    • Transcriptional regulation of cadherins during development and carcinogenesis
    • 15349812 10.1387/ijdb.041794hp 1:CAS:528:DC%2BD2cXhtVentLbL
    • Peinado H, Portillo P, Cano A (2004) Transcriptional regulation of cadherins during development and carcinogenesis. Int J Dev Biol 48:365-375
    • (2004) Int J Dev Biol , vol.48 , pp. 365-375
    • Peinado, H.1    Portillo, P.2    Cano, A.3
  • 30
    • 0037131409 scopus 로고    scopus 로고
    • Snail induction of epithelial-to-mesenchymal transition in tumor cells is accompanied by MUC-1 repression and ZEB1 expression
    • 12161443 10.1074/jbc.M206400200 1:CAS:528:DC%2BD38XnvVeisLc%3D
    • Guaita S, Puig I, Franci C et al (2002) Snail induction of epithelial-to-mesenchymal transition in tumor cells is accompanied by MUC-1 repression and ZEB1 expression. J Biol Chem 277:39209-39216
    • (2002) J Biol Chem , vol.277 , pp. 39209-39216
    • Guaita, S.1    Puig, I.2    Franci, C.3
  • 31
    • 0035215136 scopus 로고    scopus 로고
    • Reverse correlation of E-cadherin and Snail expression in oral squamous cell carcinoma cells in vitro
    • 11120485 10.1016/S1368-8375(00)00059-2 1:CAS:528:DC%2BD3cXovFKgsbY%3D
    • Yokoyama K, Kamata N, Hayashi E et al (2001) Reverse correlation of E-cadherin and Snail expression in oral squamous cell carcinoma cells in vitro. Oral Oncol 37:65-71
    • (2001) Oral Oncol , vol.37 , pp. 65-71
    • Yokoyama, K.1    Kamata, N.2    Hayashi, E.3
  • 32
    • 84858753712 scopus 로고    scopus 로고
    • Snail as a novel marker for regional metastasis in head and neck squamous cell carcinoma
    • 21439681 10.1016/j.amjoto.2010.11.018 1:CAS:528:DC%2BC3MXhsFCqsb%2FK
    • Mendelsohn AH, Lai CK, Shintaku IP et al (2012) Snail as a novel marker for regional metastasis in head and neck squamous cell carcinoma. Am J Otolaryngol 33:6-13
    • (2012) Am J Otolaryngol , vol.33 , pp. 6-13
    • Mendelsohn, A.H.1    Lai, C.K.2    Shintaku, I.P.3
  • 33
    • 84861227408 scopus 로고    scopus 로고
    • Correlation of increased twist with lymph node metastasis in patients with oral squamous cell carcinoma
    • 10.1016/j.joms.2011.06.212 21864967
    • Wushou A, Pan HY, Liu W et al (2011) Correlation of increased twist with lymph node metastasis in patients with oral squamous cell carcinoma. J Oral Maxillofac Surg. doi: 10.1016/j.joms.2011.06.212
    • (2011) J Oral Maxillofac Surg
    • Wushou, A.1    Pan, H.Y.2    Liu, W.3
  • 34
    • 30844457289 scopus 로고    scopus 로고
    • Reduced E-cadherin expression is an indicator of unfavourable prognosis in oral squamous cell carcinoma
    • 16249116 10.1016/j.oraloncology.2005.07.010 1:CAS:528: DC%2BD28XmsFShtg%3D%3D
    • Diniz-Freitas M, García-Caballero T, Antúnez-López J et al (2006) Reduced E-cadherin expression is an indicator of unfavourable prognosis in oral squamous cell carcinoma. Oral Oncol 42:190-200
    • (2006) Oral Oncol , vol.42 , pp. 190-200
    • Diniz-Freitas, M.1    García-Caballero, T.2    Antúnez-López, J.3
  • 35
    • 29944447725 scopus 로고    scopus 로고
    • Decreased E-cadherin but not b-catenin expression is associated with vascular invasion and decreased survival in head and neck squamous carcinomas
    • 16399195 10.1016/j.otohns.2005.08.026
    • Kurtz KA, Hoffman HT, Zimmerman MB et al (2006) Decreased E-cadherin but not b-catenin expression is associated with vascular invasion and decreased survival in head and neck squamous carcinomas. Otolaryngol Head Neck Surg 134:142-146
    • (2006) Otolaryngol Head Neck Surg , vol.134 , pp. 142-146
    • Kurtz, K.A.1    Hoffman, H.T.2    Zimmerman, M.B.3
  • 36
    • 84855185108 scopus 로고    scopus 로고
    • Prognostic significance of N-Cadherin expression in oral squamous cell carcinoma
    • 22199283 1:CAS:528:DC%2BC38XhsFCls70%3D
    • Di Domenico M, Pierantoni GM, Feola A et al (2011) Prognostic significance of N-Cadherin expression in oral squamous cell carcinoma. Anticancer Res 31:4211-4218
    • (2011) Anticancer Res , vol.31 , pp. 4211-4218
    • Di Domenico, M.1    Pierantoni, G.M.2    Feola, A.3
  • 37
    • 4143127943 scopus 로고    scopus 로고
    • Overexpression of hyperactive integrin-linked kinase leads to increased cellular radiosensitivity
    • 15313908 10.1158/0008-5472.CAN-04-1056 1:CAS:528:DC%2BD2cXmslalu70%3D
    • Cordes N (2004) Overexpression of hyperactive integrin-linked kinase leads to increased cellular radiosensitivity. Cancer Res 64:5683-5692
    • (2004) Cancer Res , vol.64 , pp. 5683-5692
    • Cordes, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.