Interactions of oximino-substituted boronic acids and β-lactams with the cmy-2-derived extended-spectrum cephalosporinases cmy- 30 and cmy-42

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 2, 2013, Pages 968-976

  Kotsakis, Stathis D ^a,d   Caselli, Emilia ^a,b   Tzouvelekis, Leonidas S ^a,c   Petinaki, Efi ^d   Prati, Fabio ^b   Miriagou, Vivi ^a  

^a HELLENIC PASTEUR INSTITUTE   (Greece)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^d UNIVERSITY OF THESSALY   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

BORONIC ACID TRANSITION STATE INHIBITOR; CEPHALOSPORINASE; EXTENDED SPECTRUM CEPHALOSPORINASE CMY 30; EXTENDED SPECTRUM CEPHALOSPORINASE CMY 42; HYDROLASE INHIBITOR; OXIMINO BETA LACTAM; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DYNAMICS; ENZYME INHIBITION; ENZYME STABILITY; PRIORITY JOURNAL; THERMOSTABILITY;

AMINO ACID SUBSTITUTION; BETA-LACTAMASES; BETA-LACTAMS; BORONIC ACIDS; CEPHALOSPORIN RESISTANCE; CEPHALOSPORINASE; CEPHALOSPORINS; CITROBACTER FREUNDII; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MOLECULAR DYNAMICS SIMULATION; PROTEIN STRUCTURE, TERTIARY;

EID: 84872846092     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01620-12     Document Type: Article

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