Amino Acid Sequence Determinants of Extended Spectrum Cephalosporin Hydrolysis by the Class C P99 β-Lactamase

Journal of Biological Chemistry

Volumn 276, Issue 49, 2001, Pages 46568-46574

  Zhang, Zhen ^a   Yu, Yang ^a   Musser, James M ^b   Palzkill, Timothy ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BACTERIA; CHROMOSOMES; DNA SEQUENCES; ENZYMES; HYDROLYSIS; SUBSTITUTION REACTIONS;

SUSCEPTIBLE STRAINS;

BIOTECHNOLOGY;

BETA LACTAMASE; BETA LACTAMASE C P99; CEFALORIDINE; CEFTAZIDIME; CEPHALOSPORIN DERIVATIVE; CHLORAMPHENICOL; DNA; UNCLASSIFIED DRUG; BETA LACTAMASES; PRIMER DNA;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIBIOTIC RESISTANCE; ARTICLE; CATALYSIS; CODON; CONTROLLED STUDY; DRUG BINDING; DRUG MECHANISM; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENE MUTATION; GRAM NEGATIVE BACTERIUM; HYDROLYSIS; INFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRAIN IDENTIFICATION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS;

ANIMALIA; BACTERIA (MICROORGANISMS); NEGIBACTERIA;

AMINO ACID SEQUENCE; BASE SEQUENCE; BETA-LACTAMASES; BINDING SITES; CEPHALOSPORINS; DNA PRIMERS; HYDROLYSIS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0035824615     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102757200     Document Type: Article

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