Normalization of NF-κB activity in dorsal root ganglia neurons cultured from diabetic rats reverses neuropathy-linked markers of cellular pathology

Experimental Neurology

Volumn 241, Issue 1, 2013, Pages 169-178

  Saleh, A ^a   Schapansky, J ^a,b   Smith, D R ^a,b   Young, N ^a,b   Odero, G L ^a   Aulston, B ^a,b   Fernyhough, P ^a,b   Glazner, G W ^a,b  

^a ST BONIFACE GENERAL HOSPITAL   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Axon regeneration; Calcium; Diabetic neuropathy; Lipid peroxidation; MnSOD; NF kappaB; Oxidative stress

Indexed keywords

CELL MARKER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MANGANESE SUPEROXIDE DISMUTASE; NEUROMODULIN; SHORT HAIRPIN RNA; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR REL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DIABETIC NEUROPATHY; INHIBITION KINETICS; LIPID PEROXIDATION; MALE; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NERVE SPROUTING; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SPINAL CORD NERVE CELL; SPINAL GANGLION;

ALDEHYDES; ANALYSIS OF VARIANCE; ANIMALS; AXONS; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DNA HELICASES; GANGLIA, SPINAL; GAP-43 PROTEIN; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN; MALE; NEOPLASM PROTEINS; NEURITES; NF-KAPPA B; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; SENSORY RECEPTOR CELLS; SUPEROXIDE DISMUTASE; TIME FACTORS; TRANSCRIPTION FACTOR RELA; TRANSFECTION;

EID: 84872843881     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2012.11.009     Document Type: Article

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