Mutant SOD1-induced neuronal toxicity is mediated by increased mitochondrial superoxide levels

Journal of Neurochemistry

Volumn 102, Issue 3, 2007, Pages 609-618

  Zimmerman, Matthew C ^a   Oberley, Larry W ^a   Flanagan, Shawn W ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Familial amyotrophic lateral sclerosis; Free radicals; Manganese superoxide dismutase; Neuroblastoma; Neuronal toxicity

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; MANGANESE SUPEROXIDE DISMUTASE; SUPEROXIDE;

AMYOTROPHIC LATERAL SCLEROSIS; APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; BRAIN OXYGEN CONSUMPTION; CELL DEATH; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INDUCED MUTATION; NERVE CELL CULTURE; NEUROPROTECTION; NEUROTOXICITY; OXIDATIVE STRESS; PRIORITY JOURNAL;

AMYOTROPHIC LATERAL SCLEROSIS; ANTIOXIDANTS; CELL DEATH; CELL LINE, TUMOR; CENTRAL NERVOUS SYSTEM; CYTOPROTECTION; GENETIC VECTORS; HUMANS; INDICATORS AND REAGENTS; MITOCHONDRIA; MUTATION; NERVE DEGENERATION; NEURONS; OXIDATIVE STRESS; PHENANTHRIDINES; SUPEROXIDE DISMUTASE; SUPEROXIDES; TRANSFECTION; UP-REGULATION;

ADENOVIRIDAE;

EID: 34248171278     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04502.x     Document Type: Article

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