Predicting drug release from HPMC/lactose tablets

International Journal of Pharmaceutics

Volumn 441, Issue 1-2, 2013, Pages 826-834

  Siepmann, J ^a,b   Karrout, Y ^a,b   Gehrke, M ^a,b   Penz, F K ^c   Siepmann, F ^a,b  

^a UNIV LILLE   (France)

^b France   (France)

^c BG Excipients and Technology   (Germany)

Author keywords

Diffusion; Drug release mechanism; HPMC; Lactose; Mathematical modeling; Theophylline

Indexed keywords

HYDROCHLORIC ACID; HYDROXYPROPYLMETHYLCELLULOSE; LACTOSE; PHOSPHATE; POLYMER; THEOPHYLLINE;

ANALYTIC METHOD; ARTICLE; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG RELEASE; DRUG SOLUBILITY; MATHEMATICAL MODEL; MOLECULAR WEIGHT; PH; POLYMERIZATION; PREDICTION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; TABLET FORMULATION;

DIFFUSION; EXCIPIENTS; HYDROGEN-ION CONCENTRATION; LACTOSE; METHYLCELLULOSE; MODELS, THEORETICAL; REPRODUCIBILITY OF RESULTS; SOLUBILITY; TABLETS; THEOPHYLLINE;

EID: 84872823994     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.12.009     Document Type: Article

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