Gastro-floating matrices designed for simultaneous improvement of floating and drug release capabilities: An in vitro case study of matrices loaded with ciprofloxacin hydrochloride

Journal of Drug Delivery Science and Technology

Volumn 21, Issue 3, 2011, Pages 279-281

  Shim, B H ^a   Kim, D K ^a   Ye, J S ^a   Lee, J ^a  

^a Chung Ang University   (South Korea)

Author keywords

Ciprofloxacin; Controlled release; Floating; Gastro retentive; Matrix

Indexed keywords

BICARBONATE; CIPROFLOXACIN; HYDROXYPROPYLMETHYLCELLULOSE; MAGNESIUM STEARATE; POLYOXYETHYLENE;

ARTICLE; CHEMICAL COMPOSITION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; FLOATING MATRIX TABLET; MATRIX TABLET; MOLECULAR WEIGHT; SUSTAINED DRUG RELEASE;

EID: 79959627568     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1773-2247(11)50038-3     Document Type: Article

References (12)

1. Singh B.N., Kim K.H. - Floating drug delivery systems: an approach to oral controlled drug delivery via gastric retention. - J. Control. Release, 63, 235-259, 2000.
2. Davis S.S. - Formulation strategies for absorption windows. - Drug Discov. Today, 10, 249-257, 2005.
3. Moes A.J. - Gastroretentive dosage forms. - Crit. Rev. Ther. Drug Carrier Syst., 10, 143-195, 1993.
4. Yang L., Eshraghi J., Fassihi R. - A new intragastric delivery system for the treatment of Helicobacter pilori associated gastric ulcer: in vitro evaluation. - J. Control. Release, 57, 215-222, 1999.
5. Sungthongjeen S., Sriamornsak P., Puttipipatkhachorn S. - Design and evaluation of floating multi-layer coated tablets based on gas formation.- Eur. J. Pharm. Biopharm., 69, 255-263, 2008.
6. Gambhire M.N., Ambade K.W., Kurmi S.D., Kadam V.J., Jadhav K.R. - Development and in vitro evaluation of an oral floating matrix tablet formulation of diltiazem hydrochloride. - AAPS PharmSciTech, 8, 166-174, 2007.
7. Patel D.M., Patel N.M., Pandya N.N., Jogan P.D. - Formulation and optimization of carbamazepine floating tablets. - Indian J. Pharm. Sci., 69, 763-767, 2007.
8. Sungthongjeen S., Paeratakul O., Limmatvapirat S., Puttipipatkhachorn S. - Preparation and in vitro evaluation of a multiple-unit floating drug delivery system based on gas formation technique. - Int. J. Pharm., 324, 136-143, 2006.
9. Colombo P., Conte U., Gazzaniga A., Maggi L., Sangalli M.E., Peppas N.A., La Manna A. - Drug release modulation by physical restrictions of matrix swelling. - Int. J. Pharm., 63, 43-48, 1990.
10. Staib A.H., Beermann D., Harder S., Fuhr U., Liermann D. - Absorption differences of ciprofloxacin along the human gastrointestinal tract determined using a remote-control drug delivery device (HF-capsule). - Am. J. Med., 87, 66S-69S, 1989.
11. Pillay V., Fassihi R. - Probing the dynamics of matrix hydration in the presence of electrolytes. - Drug Deliv., 8, 87-92, 2001. (Pubitemid 32494638)
12. Maggi L., Bruni R., Conte U. - High molecular weight polyethylene oxides (PEOs) as an alternative to HPMC in controlled release dosage forms. - Int. J. Pharm., 195, 229-238, 2000.