HPMC-matrices for controlled drug delivery: A new model combining diffusion, swelling, and dissolution mechanisms and predicting the release kinetics

Pharmaceutical Research

Volumn 16, Issue 11, 1999, Pages 1748-1756

  Siepmann, J ^a   Kranz, H ^a   Bodmeier, R ^a   Peppas, N A ^b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Controlled release; Diffusion; Hydroxypropyl methylcellulose (HPMC); Modeling; Polymer dissolution; Swelling

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; PROPRANOLOL;

ARTICLE; CONTROLLED DRUG RELEASE; DIFFUSION; DISSOLUTION; PRIORITY JOURNAL;

DELAYED-ACTION PREPARATIONS; DIFFUSION; LACTOSE; METHYLCELLULOSE; MODELS, CHEMICAL; OXAZINES; PROPRANOLOL; REPRODUCIBILITY OF RESULTS; SOLUBILITY; TIME FACTORS;

EID: 0032708697     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018914301328     Document Type: Article

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