Oxidative stress contributes to endothelial dysfunction in mouse models of hereditary hemorrhagic telangiectasia

Oxidative Medicine and Cellular Longevity

Volumn , Issue , 2012, Pages

  Jerkic, Mirjana ^a,b,c   Sotov, Valentin ^a,c   Letarte, Michelle ^a,b,c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMYCIN; APOCYNIN; ENDOGLIN; ENDOTHELIAL DYSFUNCTION; MOUSE MODELS; MUTANT MICE; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; RECEPTOR-LIKE KINASE; SYNTHASES; TRANSFORMING GROWTH FACTORS;

ENDOTHELIAL CELLS; ENZYME INHIBITION; TISSUE;

MAMMALS;

APOCYNIN; CITRININ; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROGEN PEROXIDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ACTIVIN RECEPTOR 1; ACVRL1 PROTEIN, MOUSE; ENDOGLIN PROTEIN, MOUSE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; RENDU OSLER WEBER DISEASE; VASCULAR ENDOTHELIUM; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; DISEASE MODEL; DRUG EFFECT; ENZYMOLOGY; HETEROZYGOTE; HUMAN; METABOLISM; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY;

MUS;

ACTIVIN RECEPTORS, TYPE I; ANIMALS; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; HETEROZYGOTE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MITOCHONDRIA; MODELS, BIOLOGICAL; NADP; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TELANGIECTASIA, HEREDITARY HEMORRHAGIC;

MLCS; MLOWN;

EID: 84872769668     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2012/686972     Document Type: Article

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