-
1
-
-
13844318259
-
The role of anticholinergics in chronic obstructive pulmonary disease
-
P.J. Barnes The role of anticholinergics in chronic obstructive pulmonary disease Am J Med 117 Suppl. 12A 2004 24S 32S
-
(2004)
Am J Med
, vol.117
, Issue.SUPPL. 12A
-
-
Barnes, P.J.1
-
2
-
-
65849427529
-
Glucocorticoid resistance in inflammatory diseases
-
P.J. Barnes, and I.M. Adcock Glucocorticoid resistance in inflammatory diseases Lancet 373 9678 2009 1905 1917
-
(2009)
Lancet
, vol.373
, Issue.9678
, pp. 1905-1917
-
-
Barnes, P.J.1
Adcock, I.M.2
-
3
-
-
39049170984
-
Global strategy for asthma management and prevention: GINA executive summary
-
E.D. Bateman, S.S. Hurd, P.J. Barnes, J. Bousquet, J.M. Drazen, and M. FitzGerald Global strategy for asthma management and prevention: GINA executive summary Eur Respir J 31 1 2008 143 178
-
(2008)
Eur Respir J
, vol.31
, Issue.1
, pp. 143-178
-
-
Bateman, E.D.1
Hurd, S.S.2
Barnes, P.J.3
Bousquet, J.4
Drazen, J.M.5
Fitzgerald, M.6
-
4
-
-
38449113726
-
Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: A comparison
-
I.S. Bos, R. Gosens, A.B. Zuidhof, D. Schaafsma, A.J. Halayko, and H. Meurs Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: a comparison Eur Respir J 30 4 2007 653 661
-
(2007)
Eur Respir J
, vol.30
, Issue.4
, pp. 653-661
-
-
Bos, I.S.1
Gosens, R.2
Zuidhof, A.B.3
Schaafsma, D.4
Halayko, A.J.5
Meurs, H.6
-
5
-
-
34447120838
-
Reducing cholinergic constriction: The major reversible mechanism in COPD
-
V. Brusasco Reducing cholinergic constriction: the major reversible mechanism in COPD Eur Respir Rev 15 99 2006 32 36
-
(2006)
Eur Respir Rev
, vol.15
, Issue.99
, pp. 32-36
-
-
Brusasco, V.1
-
6
-
-
34748819974
-
Tiotropium suppresses acetylcholine-induced release of chemotactic mediators in vitro
-
F. Bühling, N. Lieder, U.C. Kühlmann, N. Waldburg, and T. Welte Tiotropium suppresses acetylcholine-induced release of chemotactic mediators in vitro Respir Med 101 11 2007 2386 2394
-
(2007)
Respir Med
, vol.101
, Issue.11
, pp. 2386-2394
-
-
Bühling, F.1
Lieder, N.2
Kühlmann, U.C.3
Waldburg, N.4
Welte, T.5
-
7
-
-
67651014864
-
Preclinical evaluation of long-acting muscarinic antagonists: Comparison of tiotropium and investigational drugs
-
P. Casarosa, T. Bouyssou, S. Germeyer, A. Schnapp, F. Gantner, and M. Pieper Preclinical evaluation of long-acting muscarinic antagonists: comparison of tiotropium and investigational drugs J Pharmacol Exp Ther 330 2 2009 660 668
-
(2009)
J Pharmacol Exp Ther
, vol.330
, Issue.2
, pp. 660-668
-
-
Casarosa, P.1
Bouyssou, T.2
Germeyer, S.3
Schnapp, A.4
Gantner, F.5
Pieper, M.6
-
8
-
-
0001926599
-
History of anticholinergic tratment in airways diseases
-
N.J. Gross, Franklin Scientific Publications London
-
K.R. Chapman History of anticholinergic tratment in airways diseases N.J. Gross, Anticholinergic therapy in obstructive airways disease 1993 Franklin Scientific Publications London 9 18
-
(1993)
Anticholinergic Therapy in Obstructive Airways Disease
, pp. 9-18
-
-
Chapman, K.R.1
-
9
-
-
79953646222
-
Aclidinium inhibits cholinergic and tobacco smoke-induced MUC5AC in human airways
-
J. Cortijo, M. Mata, J. Milara, E. Donet, A. Gavaldà, and M. Miralpeix Aclidinium inhibits cholinergic and tobacco smoke-induced MUC5AC in human airways Eur Respir J 37 2 2011 244 254
-
(2011)
Eur Respir J
, vol.37
, Issue.2
, pp. 244-254
-
-
Cortijo, J.1
Mata, M.2
Milara, J.3
Donet, E.4
Gavaldà, A.5
Miralpeix, M.6
-
10
-
-
78049265848
-
Aclidinium bromide abrogates allergen-induced hyperresponsiveness and reduces eosinophilia in murine model of airway inflammation
-
G. Damera, M. Jiang, H. Zhao, H.W. Fogle, W.F. Jester, and J. Freire Aclidinium bromide abrogates allergen-induced hyperresponsiveness and reduces eosinophilia in murine model of airway inflammation Eur J Pharmacol 649 1-3 2010 349 353
-
(2010)
Eur J Pharmacol
, vol.649
, Issue.13
, pp. 349-353
-
-
Damera, G.1
Jiang, M.2
Zhao, H.3
Fogle, H.W.4
Jester, W.F.5
Freire, J.6
-
11
-
-
55949136832
-
Effect of tiotropium on cough reflex sensitivity in acute viral cough
-
P.V. Dicpinigaitis, L. Spinner, G. Santhyadka, and A. Negassa Effect of tiotropium on cough reflex sensitivity in acute viral cough Lung 186 6 2008 369 374
-
(2008)
Lung
, vol.186
, Issue.6
, pp. 369-374
-
-
Dicpinigaitis, P.V.1
Spinner, L.2
Santhyadka, G.3
Negassa, A.4
-
12
-
-
0027446311
-
Ba 679 BR, a novel long-acting anticholinergic bronchodilator
-
B. Disse, R. Reichl, G. Speck, W. Traunecker, K.L. Ludwig Rominger, and R. Hammer Ba 679 BR, a novel long-acting anticholinergic bronchodilator Life Sci 52 5-6 1993 537 544
-
(1993)
Life Sci
, vol.52
, Issue.56
, pp. 537-544
-
-
Disse, B.1
Reichl, R.2
Speck, G.3
Traunecker, W.4
Ludwig Rominger, K.L.5
Hammer, R.6
-
13
-
-
78649735324
-
Airway mucus function and dysfunction
-
J.V. Fahy, and B.F. Dickey Airway mucus function and dysfunction N Engl J Med 363 23 2010 2233 2247
-
(2010)
N Engl J Med
, vol.363
, Issue.23
, pp. 2233-2247
-
-
Fahy, J.V.1
Dickey, B.F.2
-
14
-
-
18644380685
-
Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling
-
R. Gosens, I.S. Bos, J. Zaagsma, and H. Meurs Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling Am J Respir Crit Care Med 171 10 2005 1096 1102
-
(2005)
Am J Respir Crit Care Med
, vol.171
, Issue.10
, pp. 1096-1102
-
-
Gosens, R.1
Bos, I.S.2
Zaagsma, J.3
Meurs, H.4
-
15
-
-
0037470635
-
Introduction: The non-neuronal cholinergic system in humans
-
S.A. Grando, K. Kawashima, and I. Wessler Introduction: the non-neuronal cholinergic system in humans Life Sci 72 18-19 2003 2009 2012
-
(2003)
Life Sci
, vol.72
, Issue.1819
, pp. 2009-2012
-
-
Grando, S.A.1
Kawashima, K.2
Wessler, I.3
-
16
-
-
33644763963
-
Anticholinergic agents in asthma and COPD
-
N.J. Gross Anticholinergic agents in asthma and COPD Eur J Pharmacol 533 1-3 2006 36 39
-
(2006)
Eur J Pharmacol
, vol.533
, Issue.13
, pp. 36-39
-
-
Gross, N.J.1
-
17
-
-
0024467177
-
Cholinergic bronchomotor tone in COPD
-
N.J. Gross, E. Co, and M.S. Skorodin Cholinergic bronchomotor tone in COPD Chest 96 5 1989 984 987
-
(1989)
Chest
, vol.96
, Issue.5
, pp. 984-987
-
-
Gross, N.J.1
Co, E.2
Skorodin, M.S.3
-
18
-
-
60849113110
-
Suitability of muscarinic acetylcholine receptor antibodies for immunohistochemistry evaluated on tissue sections of receptor gene-deficient mice
-
G. Jositsch, T. Papadakis, R.V. Haberberger, M. Wolff, J. Wess, and W. Kummer Suitability of muscarinic acetylcholine receptor antibodies for immunohistochemistry evaluated on tissue sections of receptor gene-deficient mice Naunyn Schmiedebergs Arch Pharmacol 379 4 2009 389 395
-
(2009)
Naunyn Schmiedebergs Arch Pharmacol
, vol.379
, Issue.4
, pp. 389-395
-
-
Jositsch, G.1
Papadakis, T.2
Haberberger, R.V.3
Wolff, M.4
Wess, J.5
Kummer, W.6
-
19
-
-
79961016525
-
Tiotropium improves lung function in patients with severe uncontrolled asthma: A randomized controlled trial
-
H.A. Kerstjens, B. Disse, W. Schröder-Babo, T.A. Bantje, and M. Gahlemann Tiotropium improves lung function in patients with severe uncontrolled asthma: a randomized controlled trial J Allergy Clin Immunol 128 2 2011 308 314
-
(2011)
J Allergy Clin Immunol
, vol.128
, Issue.2
, pp. 308-314
-
-
Kerstjens, H.A.1
Disse, B.2
Schröder-Babo, W.3
Bantje, T.A.4
Gahlemann, M.5
-
20
-
-
0026697298
-
Acetylcholine stimulates bronchial epithelial cells to release neutrophil and monocyte chemotactic activity
-
S. Koyama, S.I. Rennard, and R.A. Robbins Acetylcholine stimulates bronchial epithelial cells to release neutrophil and monocyte chemotactic activity Am J Physiol 262 4 Pt 1 1992 L466 L471
-
(1992)
Am J Physiol
, vol.262
, Issue.4 PART 1
-
-
Koyama, S.1
Rennard, S.I.2
Robbins, R.A.3
-
21
-
-
9644255930
-
Mechanisms of chronic cough
-
L.Y. Lee, and B.J. Undem Mechanisms of chronic cough Pulm Pharmacol Ther 17 6 2004 463 464
-
(2004)
Pulm Pharmacol Ther
, vol.17
, Issue.6
, pp. 463-464
-
-
Lee, L.Y.1
Undem, B.J.2
-
22
-
-
33845397124
-
Muscarinic receptors mediate stimulation of human lung fibroblast proliferation
-
S. Matthiesen, A. Bahulayan, S. Kempkens, S. Haag, M. Fuhrmann, and C. Stichnote Muscarinic receptors mediate stimulation of human lung fibroblast proliferation Am J Respir Cell Mol Biol 35 6 2006 621 627
-
(2006)
Am J Respir Cell Mol Biol
, vol.35
, Issue.6
, pp. 621-627
-
-
Matthiesen, S.1
Bahulayan, A.2
Kempkens, S.3
Haag, S.4
Fuhrmann, M.5
Stichnote, C.6
-
23
-
-
84857444788
-
Aclidinium inhibits human lung fibroblast to myofibroblast transition
-
J. Milara, A. Serrano, T. Peiró, A. Gavaldà, M. Miralpeix, and E.J. Morcillo Aclidinium inhibits human lung fibroblast to myofibroblast transition Thorax 67 3 2011 229 237
-
(2011)
Thorax
, vol.67
, Issue.3
, pp. 229-237
-
-
Milara, J.1
Serrano, A.2
Peiró, T.3
Gavaldà, A.4
Miralpeix, M.5
Morcillo, E.J.6
-
24
-
-
0031001720
-
Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study
-
C.J. Murray, and A.D. Lopez Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study Lancet 349 9064 1997 1498 1504
-
(1997)
Lancet
, vol.349
, Issue.9064
, pp. 1498-1504
-
-
Murray, C.J.1
Lopez, A.D.2
-
25
-
-
77954357471
-
Effect of tiotropium bromide on airway inflammation and remodelling in a mouse model of asthma
-
S. Ohta, N. Oda, T. Yokoe, A. Tanaka, Y. Yamamoto, and Y. Watanabe Effect of tiotropium bromide on airway inflammation and remodelling in a mouse model of asthma Clin Exp Allergy 40 8 2010 1266 1275
-
(2010)
Clin Exp Allergy
, vol.40
, Issue.8
, pp. 1266-1275
-
-
Ohta, S.1
Oda, N.2
Yokoe, T.3
Tanaka, A.4
Yamamoto, Y.5
Watanabe, Y.6
-
26
-
-
33751111748
-
Synergistic effects of the anti-cholinergic R,R-glycopyrrolate with anti-inflammatory drugs
-
A. Pahl, A. Bauhofer, U. Petzold, P.J. Cnota, J. Maus, and K. Brune Synergistic effects of the anti-cholinergic R,R-glycopyrrolate with anti-inflammatory drugs Biochem Pharmacol 72 12 2006 1690 1696
-
(2006)
Biochem Pharmacol
, vol.72
, Issue.12
, pp. 1690-1696
-
-
Pahl, A.1
Bauhofer, A.2
Petzold, U.3
Cnota, P.J.4
Maus, J.5
Brune, K.6
-
27
-
-
80052940501
-
Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD
-
T. Pera, A. Zuidhof, J. Valadas, M. Smit, R.G. Schoemaker, and R. Gosens Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD Eur Respir J 38 4 2011 789 796
-
(2011)
Eur Respir J
, vol.38
, Issue.4
, pp. 789-796
-
-
Pera, T.1
Zuidhof, A.2
Valadas, J.3
Smit, M.4
Schoemaker, R.G.5
Gosens, R.6
-
28
-
-
77957768543
-
National Heart, Lung, and Blood Institute Asthma Clinical Research Network. Tiotropium bromide step-up therapy for adults with uncontrolled asthma
-
S.P. Peters, S.J. Kunselman, N. Icitovic, W.C. Moore, R. Pascual, and B.T. Ameredes National Heart, Lung, and Blood Institute Asthma Clinical Research Network. Tiotropium bromide step-up therapy for adults with uncontrolled asthma N Engl J Med 363 18 2010 1715 1726
-
(2010)
N Engl J Med
, vol.363
, Issue.18
, pp. 1715-1726
-
-
Peters, S.P.1
Kunselman, S.J.2
Icitovic, N.3
Moore, W.C.4
Pascual, R.5
Ameredes, B.T.6
-
29
-
-
34249338661
-
Acetylcholine-induced proliferation of fibroblasts and myofibroblasts in vitro is inhibited by tiotropium bromide
-
M.P. Pieper, N.I. Chaudhary, and J.E. Park Acetylcholine-induced proliferation of fibroblasts and myofibroblasts in vitro is inhibited by tiotropium bromide Life Sci 80 24-25 2007 2270 2273
-
(2007)
Life Sci
, vol.80
, Issue.2425
, pp. 2270-2273
-
-
Pieper, M.P.1
Chaudhary, N.I.2
Park, J.E.3
-
30
-
-
37849014833
-
Effect of tiotropium on sputum and serum inflammatory markers and exacerbations in COPD
-
D.J. Powrie, T.M. Wilkinson, G.C. Donaldson, P. Jones, K. Scrine, and K. Viel Effect of tiotropium on sputum and serum inflammatory markers and exacerbations in COPD Eur Respir J 30 3 2007 472 478
-
(2007)
Eur Respir J
, vol.30
, Issue.3
, pp. 472-478
-
-
Powrie, D.J.1
Wilkinson, T.M.2
Donaldson, G.C.3
Jones, P.4
Scrine, K.5
Viel, K.6
-
31
-
-
26944437890
-
Muscarinic receptors, leukotriene B4 production and neutrophilic inflammation in COPD patients
-
M. Profita, R.D. Giorgi, A. Sala, A. Bonanno, L. Riccobono, and F. Mirabella Muscarinic receptors, leukotriene B4 production and neutrophilic inflammation in COPD patients Allergy 60 11 2005 1361 1369
-
(2005)
Allergy
, vol.60
, Issue.11
, pp. 1361-1369
-
-
Profita, M.1
Giorgi, R.D.2
Sala, A.3
Bonanno, A.4
Riccobono, L.5
Mirabella, F.6
-
32
-
-
34548660457
-
Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
-
K.F. Rabe, S. Hurd, A. Anzueto, P.J. Barnes, S.A. Buist, and P. Calverley Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary Am J Respir Crit Care Med 176 6 2007 532 555
-
(2007)
Am J Respir Crit Care Med
, vol.176
, Issue.6
, pp. 532-555
-
-
Rabe, K.F.1
Hurd, S.2
Anzueto, A.3
Barnes, P.J.4
Buist, S.A.5
Calverley, P.6
-
33
-
-
84865009540
-
Bronchodilators modulate inflammation in chronic obstructive pulmonary disease subjects
-
P. Santus, C. Buccellati, S. Centanni, F. Fumagalli, P. Busatto, and F. Blasi Bronchodilators modulate inflammation in chronic obstructive pulmonary disease subjects Pharmacol Res 66 4 2012 343 348
-
(2012)
Pharmacol Res
, vol.66
, Issue.4
, pp. 343-348
-
-
Santus, P.1
Buccellati, C.2
Centanni, S.3
Fumagalli, F.4
Busatto, P.5
Blasi, F.6
-
34
-
-
0028125006
-
Effect of Ba 679 BR, a novel long-acting anticholinergic agent, on cholinergic neurotransmission in guinea pig and human airways
-
T. Takahashi, M.G. Belvisi, H. Patel, J.K. Ward, S. Tadjkarimi, and M.H. Yacoub Effect of Ba 679 BR, a novel long-acting anticholinergic agent, on cholinergic neurotransmission in guinea pig and human airways Am J Respir Crit Care Med 150 6 Pt 1 1994 1640 1645
-
(1994)
Am J Respir Crit Care Med
, vol.150
, Issue.6 PART 1
, pp. 1640-1645
-
-
Takahashi, T.1
Belvisi, M.G.2
Patel, H.3
Ward, J.K.4
Tadjkarimi, S.5
Yacoub, M.H.6
-
35
-
-
53749102775
-
A 4-year trial of tiotropium in chronic obstructive pulmonary disease
-
D.P. Tashkin, B. Celli, S. Senn, D. Burkhart, S. Kesten, and S. Menjoge A 4-year trial of tiotropium in chronic obstructive pulmonary disease N Engl J Med 359 15 2008 1543 1554
-
(2008)
N Engl J Med
, vol.359
, Issue.15
, pp. 1543-1554
-
-
Tashkin, D.P.1
Celli, B.2
Senn, S.3
Burkhart, D.4
Kesten, S.5
Menjoge, S.6
-
36
-
-
0037180778
-
The inflammatory reflex
-
K.J. Tracey The inflammatory reflex Nature 420 6917 2002 853 859
-
(2002)
Nature
, vol.420
, Issue.6917
, pp. 853-859
-
-
Tracey, K.J.1
-
37
-
-
77954650588
-
Tiotropium as a first maintenance drug in COPD: Secondary analysis of the UPLIFT trial
-
T. Troosters, B. Celli, T. Lystig, S. Kesten, S. Mehra, and Uplift Investigators Tiotropium as a first maintenance drug in COPD: secondary analysis of the UPLIFT trial Eur Respir J 36 1 2010 65 73
-
(2010)
Eur Respir J
, vol.36
, Issue.1
, pp. 65-73
-
-
Troosters, T.1
Celli, B.2
Lystig, T.3
Kesten, S.4
Mehra, S.5
-
38
-
-
79953166862
-
Tiotropium versus salmeterol for the prevention of exacerbations of COPD
-
C. Vogelmeier, B. Hederer, T. Glaab, H. Schmidt, M.P. Rutten-van Mölken, and K.M. Beeh Tiotropium versus salmeterol for the prevention of exacerbations of COPD N Engl J Med 364 12 2011 1093 1103
-
(2011)
N Engl J Med
, vol.364
, Issue.12
, pp. 1093-1103
-
-
Vogelmeier, C.1
Hederer, B.2
Glaab, T.3
Schmidt, H.4
Rutten-Van Mölken, M.P.5
Beeh, K.M.6
-
39
-
-
0035683136
-
The Non-neuronal cholinergic system: An emerging drug target in the airways
-
I.K. Wessler, and C.J. Kirkpatrick The Non-neuronal cholinergic system: an emerging drug target in the airways Pulm Pharmacol Ther 14 6 2001 423 434
-
(2001)
Pulm Pharmacol Ther
, vol.14
, Issue.6
, pp. 423-434
-
-
Wessler, I.K.1
Kirkpatrick, C.J.2
-
40
-
-
0033033206
-
The cholinergic 'pitfall': Acetylcholine, a universal cell molecule in biological systems, including humans
-
I. Wessler, C.J. Kirkpatrick, and K. Racké The cholinergic 'pitfall': acetylcholine, a universal cell molecule in biological systems, including humans Clin Exp Pharmacol Physiol 26 3 1999 198 205
-
(1999)
Clin Exp Pharmacol Physiol
, vol.26
, Issue.3
, pp. 198-205
-
-
Wessler, I.1
Kirkpatrick, C.J.2
Racké, K.3
-
41
-
-
77953123408
-
Tiotropium bromide exerts anti-inflammatory activity in a cigarette smoke mouse model of COPD
-
L. Wollin, and M.P. Pieper Tiotropium bromide exerts anti-inflammatory activity in a cigarette smoke mouse model of COPD Pulm Pharmacol Ther 23 4 2010 345 354
-
(2010)
Pulm Pharmacol Ther
, vol.23
, Issue.4
, pp. 345-354
-
-
Wollin, L.1
Pieper, M.P.2
-
42
-
-
40549141106
-
Basic and clinical aspects of non-neuronal acetylcholine: Expression of non-neuronal acetylcholine in urothelium and its clinical significance
-
M. Yoshida, K. Masunaga, Y. Satoji, Y. Maeda, T. Nagata, and A. Inadome Basic and clinical aspects of non-neuronal acetylcholine: expression of non-neuronal acetylcholine in urothelium and its clinical significance J Pharmacol Sci 106 2 2008 193 198
-
(2008)
J Pharmacol Sci
, vol.106
, Issue.2
, pp. 193-198
-
-
Yoshida, M.1
Masunaga, K.2
Satoji, Y.3
Maeda, Y.4
Nagata, T.5
Inadome, A.6
|