Preclinical evaluation of long-acting muscarinic antagonists: Comparison of tiotropium and investigational drugs

Journal of Pharmacology and Experimental Therapeutics

Volumn 330, Issue 2, 2009, Pages 660-668

  Casarosa, Paola ^a,b   Bouyssou, Thierry ^a   Germeyer, Sabine ^a   Schnapp, Andreas ^a   Gantner, Florian ^a   Pieper, Michael ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b BI Pharma ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACLIDINIUM BROMIDE; ATROPINE; GLYCOPYRRONIUM BROMIDE; IPRATROPIUM BROMIDE; LONG ACTING DRUG; METHYLSCOPOLAMINE; MUSCARINIC M3 RECEPTOR; PIRENZEPINE; SCOPOLAMINE METHYL CHLORIDE; TIOTROPIUM BROMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHODILATATION; BRONCHOSPASM; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DOG; DOSE CALCULATION; DRUG EFFECT; DRUG HALF LIFE; DRUG POTENCY; DRUG RECEPTOR BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; RECEPTOR AFFINITY;

ANIMALS; BINDING SITES; BRONCHOCONSTRICTION; CHO CELLS; CRICETINAE; CRICETULUS; DELAYED-ACTION PREPARATIONS; DOGS; DRUG EVALUATION, PRECLINICAL; DRUGS, INVESTIGATIONAL; HUMANS; MALE; MUSCARINIC ANTAGONISTS; PROTEIN BINDING; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECEPTORS, MUSCARINIC; SCOPOLAMINE DERIVATIVES;

EID: 67651014864     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.152470     Document Type: Article

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