Hepatic Cyp2d and Cyp26a1 mRNAs and activities are increased during mouse pregnancys

Drug Metabolism and Disposition

Volumn 41, Issue 2, 2013, Pages 312-319

  Topletz, Ariel R ^a   Le, Huong N ^a   Lee, Nora ^a   Chapman, John D ^a   Kelly, Edward J ^a   Wang, Joanne ^a   Isoherranen, Nina ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 26A1; CYTOCHROME P450 2D; CYTOCHROME P450 2D11; CYTOCHROME P450 2D22; CYTOCHROME P450 2D26; CYTOCHROME P450 2D40; DEXTROMETHORPHAN; DEXTRORPHAN; DNA; MESSENGER RNA; RETINOIC ACID; RETINOIC ACID RECEPTOR BETA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CLEARANCE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DNA SEQUENCE; DRUG METABOLISM; ENERGY BALANCE; ENZYME ACTIVITY; ENZYME ANALYSIS; FEMALE; GENE EXPRESSION; GESTATION PERIOD; LIVER HOMOGENATE; LIVER METABOLISM; MOLECULAR PROBE; MOUSE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROMOTER REGION; RETINOIC ACID RESPONSIVE ELEMENT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; BINDING SITES; CYTOCHROME P-450 ENZYME SYSTEM; DEXTROMETHORPHAN; DEXTRORPHAN; ENZYME INDUCTION; FEMALE; HYDROXYLATION; LIVER; MICE; MODELS, ANIMAL; PREGNANCY; RECEPTORS, RETINOIC ACID; RESPONSE ELEMENTS; RNA, MESSENGER; SUBSTRATE SPECIFICITY; TRETINOIN;

EID: 84872739905     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.112.049379     Document Type: Article

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