N-myc downstream-regulated gene 1 (NDRG1) a differentiation marker of human breast cancer

Pathology and Oncology Research

Volumn 17, Issue 3, 2011, Pages 525-533

  Fotovati, Abbas ^a,b,c   Abu Ali, Samah ^c   Kage, Masayoshi ^a,d   Shirouzu, Kazuo ^d   Yamana, Hideaki ^d   Kuwano, Michihiko ^e  

^a KURUME UNIVERSITY   (Japan)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c Laboratory of Biomedical Research   (Japan)

^d KURUME UNIVERSITY HOSPITAL   (Japan)

^e KYUSHU UNIVERSITY   (Japan)

Author keywords

Anticancer differentiation therapy; Breast cancer; Cancer biomarkers; Cap43; Differentiation; NDRG1

Indexed keywords

BETA CASEIN; BIOLOGICAL MARKER; BUTYRIC ACID; DIFFERENTIATION REGULATED GENE 1; MILK PROTEIN; MYC PROTEIN; N MYC DOWNSTREAM REGULATED GENE 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTIGENS, DIFFERENTIATION; BLOTTING, WESTERN; BREAST NEOPLASMS; CASEINS; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL LINE, TUMOR; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, NUDE; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 80052745976     PISSN: 12194956     EISSN: 15322807     Source Type: Journal    
DOI: 10.1007/s12253-010-9342-y     Document Type: Article

References (39)

1. D Zhou K Salnikow M Costa 1998 Cap43, a novel gene specifically induced by ni2+ compounds Cancer Res 58 10 2182 2189 9605764 1:CAS:528: DyaK1cXjt12ht70%3D (Pubitemid 28232906)
2. N van Belzen WN Dinjens MP Diesveld NA Groen AC van der Made Y Nozawa R Vlietstra J Trapman FT Bosman 1997 A novel gene which is up-regulated during colon epithelial cell differentiation and down-regulated in colorectal neoplasms Lab Invest 77 1 85 92 9251681 (Pubitemid 27328362)
3. A Shimono T Okuda H Kondoh 1999 N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cdnas between wild type and n-myc mutant Mech Dev 83 1-2 39 52 10381566 10.1016/S0925-4773(99) 00025-8 1:CAS:528:DyaK1MXjs1Shtro%3D (Pubitemid 29302080)
4. SK Kurdistani P Arizti CL Reimer MM Sugrue SA Aaronson SW Lee 1998 Inhibition of tumor cell growth by rtp/rit42 and its responsiveness to p53 and DNA damage Cancer Res 58 19 4439 4444 9766676 1:CAS:528:DyaK1cXmsVyqtrk%3D (Pubitemid 28450049)
5. K Salnikow T Kluz M Costa 1999 Role of ca(2+) in the regulation of nickel-inducible cap43 gene expression Toxicol Appl Pharmacol 160 2 127 132 10527911 10.1006/taap.1999.8759 1:CAS:528:DyaK1MXms1ymsL8%3D (Pubitemid 29498396)
6. K Masuda M Ono M Okamoto W Morikawa M Otsubo T Migita M Tsuneyoshi H Okuda T Shuin S Naito M Kuwano 2003 Downregulation of cap43 gene by von hippel-lindau tumor suppressor protein in human renal cancer cells Int J Cancer 105 6 803 810 12767066 10.1002/ijc.11152 1:CAS:528:DC%2BD3sXltVSisLg%3D (Pubitemid 36706104)
7. H Park MA Adams P Lachat F Bosman SC Pang CH Graham 2000 Hypoxia induces the expression of a 43-kda protein (proxy-1) in normal and malignant cells Biochem Biophys Res Commun 276 1 321 328 11006124 10.1006/bbrc.2000.3475 1:CAS:528:DC%2BD3cXmslKnurY%3D
8. A Nishie K Masuda M Otsubo T Migita M Tsuneyoshi K Kohno T Shuin S Naito M Ono M Kuwano 2001 High expression of the cap43 gene in infiltrating macrophages of human renal cell carcinomas Clin Cancer Res 7 7 2145 2151 11448934 1:CAS:528:DC%2BD3MXlslaksro%3D (Pubitemid 32994855)
9. H Okuda S Hirai Y Takaki M Kamada M Baba N Sakai T Kishida S Kaneko M Yao S Ohno T Shuin 1999 Direct interaction of the beta-domain of vhl tumor suppressor protein with the regulatory domain of atypical pkc isotypes Biochem Biophys Res Commun 263 2 491 497 10491320 10.1006/bbrc.1999.1347 1:CAS:528:DyaK1MXlvFansb0%3D (Pubitemid 29467223)
10. P Lachat P Shaw S Gebhard N van Belzen P Chaubert FT Bosman 2002 Expression of ndrg1, a differentiation-related gene, in human tissues Histochem Cell Biol 118 5 399 408 12432451 10.1007/s00418-002-0460-9 1:CAS:528: DC%2BD38Xos1eltLk%3D (Pubitemid 35352125)
11. Y Wakisaka A Furuta K Masuda W Morikawa M Kuwano T Iwaki 2003 Cellular distribution of ndrg1 protein in the rat kidney and brain during normal postnatal development J Histochem Cytochem 51 11 1515 1525 14566023 10.1177/002215540305101111 1:CAS:528:DC%2BD3sXpsVCit7g%3D (Pubitemid 37444539)
12. T Okuda Y Higashi K Kokame C Tanaka H Kondoh T Miyata 2004 Ndrg1-deficient mice exhibit a progressive demyelinating disorder of peripheral nerves Mol Cell Biol 24 9 3949 3956 15082788 10.1128/MCB.24.9.3949-3956.2004 1:CAS:528:DC%2BD2cXjsVyrsLY%3D (Pubitemid 38496172)
13. K Hirata K Masuda W Morikawa JW He A Kuraoka M Kuwano M Kawabuchi 2004 N-myc downstream-regulated gene 1 expression in injured sciatic nerves Glia 47 4 325 334 15293230 10.1002/glia.20037 (Pubitemid 39295416)
14. RJ Guan HL Ford Y Fu Y Li LM Shaw AB Pardee 2000 Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer Cancer Res 60 3 749 755 10676663 1:CAS:528:DC%2BD3cXht1Gmur0%3D (Pubitemid 30094577)
15. S Bandyopadhyay SK Pai SC Gross S Hirota S Hosobe K Miura K Saito T Commes S Hayashi M Watabe K Watabe 2003 The drg-1 gene suppresses tumor metastasis in prostate cancer Cancer Res 63 8 1731 1736 12702552 1:CAS:528:DC%2BD3sXivFygu7Y%3D (Pubitemid 36460828)
16. S Bandyopadhyay SK Pai S Hirota S Hosobe Y Takano K Saito D Piquemal T Commes M Watabe SC Gross Y Wang S Ran K Watabe 2004 Role of the putative tumor metastasis suppressor gene drg-1 in breast cancer progression Oncogene 23 33 5675 5681 15184886 10.1038/sj.onc.1207734 1:CAS:528:DC%2BD2cXlvVehs7Y%3D (Pubitemid 39093045)
17. A Fotovati T Fujii M Yamaguchi M Kage K Shirouzu S Oie Y Basaki M Ono H Yamana M Kuwano 2006 17beta-estradiol induces down-regulation of cap43/ndrg1/drg-1, a putative differentiation-related and metastasis suppressor gene, in human breast cancer cells Clin Cancer Res 12 10 3010 3018 16707596 10.1158/1078-0432.CCR-05-1962 1:CAS:528:DC%2BD28Xks1CitrY%3D (Pubitemid 43837345)
18. Ozpolat B (2009) Resistance to differentiation therapy. In: Mehta K and Siddik ZH (eds) Drug resistance in cancer cells, 1st edn. Springer, New York
19. M Leszczyniecka T Roberts P Dent S Grant PB Fisher 2001 Differentiation therapy of human cancer: Basic science and clinical applications Pharmacol Ther 90 2-3 105 156 11578655 10.1016/S0163-7258(01)00132-2 1:CAS:528: DC%2BD3MXntV2htbY%3D (Pubitemid 32926714)
20. TR Breitman SE Selonick SJ Collins 1980 Induction of differentiation of the human promyelocytic leukemia cell line (hl-60) by retinoic acid Proc Natl Acad Sci U S A 77 5 2936 2940 6930676 10.1073/pnas.77.5.2936 1:CAS:528:DyaL3cXktlOjs7s%3D (Pubitemid 10049852)
21. E Huberman MF Callaham 1979 Induction of terminal differentiation in human promyelocytic leukemia cells by tumor-promoting agents Proc Natl Acad Sci U S A 76 3 1293 1297 286311 10.1073/pnas.76.3.1293 1:CAS:528:DyaE1MXktVWju7c%3D (Pubitemid 9143726)
22. AA Lane BA Chabner 2009 Histone deacetylase inhibitors in cancer therapy J Clin Oncol 27 32 5459 5468 19826124 10.1200/JCO.2009.22.1291 1:CAS:528:DC%2BD1MXhsFKkt7vE
23. D Piquemal D Joulia P Balaguer A Basset J Marti T Commes 1999 Differential expression of the rtp/drg1/ndr1 gene product in proliferating and growth arrested cells Biochim Biophys Acta 1450 3 364 373 10395947 10.1016/S0167-4889(99)00056-7 1:CAS:528:DyaK1MXks1Cksr4%3D (Pubitemid 29295486)
24. A Munshi JF Kurland T Nishikawa T Tanaka ML Hobbs SL Tucker S Ismail C Stevens RE Meyn 2005 Histone deacetylase inhibitors radiosensitize human melanoma cells by suppressing DNA repair activity Clin Cancer Res 11 13 4912 4922 16000590 10.1158/1078-0432.CCR-04-2088 1:CAS:528:DC%2BD2MXlvVGgsb8%3D (Pubitemid 41557212)
25. SD Gore LJ Weng S Zhai WD Figg RC Donehower GJ Dover M Grever CA Griffin LB Grochow EK Rowinsky Y Zabalena AL Hawkins K Burks CB Miller 2001 Impact of the putative differentiating agent sodium phenylbutyrate on myelodysplastic syndromes and acute myeloid leukemia Clin Cancer Res 7 8 2330 2339 11489809 1:CAS:528:DC%2BD3MXmsVOmt70%3D (Pubitemid 32751632)
26. V Santini A Gozzini B Scappini A Grossi P Rossi Ferrini 2001 Searching for the magic bullet against cancer: the butyrate saga Leuk Lymphoma 42 3 275 289 11699392 10.3109/10428190109064584 1:CAS:528:DC%2BD3MXmtlSlt7o%3D (Pubitemid 32725584)
27. RP Warrell Jr LZ He V Richon E Calleja PP Pandolfi 1998 Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase J Natl Cancer Inst 90 21 1621 1625 9811311 10.1093/jnci/90.21.1621 1:CAS:528:DyaK1cXnsVCgt7k%3D (Pubitemid 28523436)
28. A Gozzini E Rovida P Dello Sbarba S Galimberti V Santini 2003 Butyrates, as a single drug, induce histone acetylation and granulocytic maturation: possible selectivity on core binding factor-acute myeloid leukemia blasts Cancer Res 63 24 8955 8961 14695213 1:CAS:528:DC%2BD3sXhtVSqtbnP (Pubitemid 38064076)
29. Y Maruyama M Ono A Kawahara T Yokoyama Y Basaki M Kage S Aoyagi H Kinoshita M Kuwano 2006 Tumor growth suppression in pancreatic cancer by a putative metastasis suppressor gene cap43/ndrg1/drg-1 through modulation of angiogenesis Cancer Res 66 12 6233 6242 16778198 10.1158/0008-5472.CAN-06-0183 1:CAS:528:DC%2BD28XlvVSkt7s%3D
30. J Russo D Mailo YF Hu G Balogh F Sheriff IH Russo 2005 Breast differentiation and its implication in cancer prevention Clin Cancer Res 11 2 Pt 2 931s 936s 15701889 1:CAS:528:DC%2BD2MXislWnsrk%3D (Pubitemid 40111108)
31. J Russo YF Hu ID Silva IH Russo 2001 Cancer risk related to mammary gland structure and development Microsc Res Tech 52 2 204 223 11169868 10.1002/1097-0029(20010115)52:2<204::AID-JEMT1006>3.0.CO;2-F 1:CAS:528:DC%2BD3MXhtlajurg%3D (Pubitemid 32107808)
32. RJ CG IH Russo 1993 Critical approach to the malignant transformation of human breast epithelial cells CRC Crit Rev Oncog 4 403 417
33. J Russo BA Gusterson AE Rogers IH Russo SR Wellings MJ van Zwieten 1990 Comparative study of human and rat mammary tumorigenesis Lab Invest 62 3 244 278 2107367 1:STN:280:DyaK3c7ovFOksw%3D%3D (Pubitemid 20124262)
34. H Kouros-Mehr SK Bechis EM Slorach LE Littlepage M Egeblad AJ Ewald SY Pai IC Ho Z Werb 2008 Gata-3 links tumor differentiation and dissemination in a luminal breast cancer model Cancer Cell 13 2 141 152 18242514 10.1016/j.ccr.2008.01.011 1:CAS:528:DC%2BD1cXitFWrs7Y%3D (Pubitemid 351163164)
35. N van Belzen WN Dinjens BH Eussen FT Bosman 1998 Expression of differentiation-related genes in colorectal cancer: possible implications for prognosis Histol Histopathol 13 4 1233 1242 9810514 (Pubitemid 28480378)
36. DW Visscher RJ Zarbo KA Greenawald JD Crissman 1990 Prognostic significance of morphological parameters and flow cytometric DNA analysis in carcinoma of the breast Pathol Annu 25 Pt 1 171 210 2153277
37. DL Page 1991 Prognosis and breast cancer. Recognition of lethal and favorable prognostic types Am J Surg Pathol 15 4 334 349 2006713 10.1097/00000478-199104000-00002 1:STN:280:DyaK3M7nsVWisA%3D%3D
38. MA Shah J Kortmansky M Motwani M Drobnjak M Gonen S Yi A Weyerbacher C Cordon-Cardo R Lefkowitz B Brenner E O'Reilly L Saltz W Tong DP Kelsen GK Schwartz 2005 A phase i clinical trial of the sequential combination of irinotecan followed by flavopiridol Clin Cancer Res 11 10 3836 3845 15897584 10.1158/1078-0432.CCR-04-2651 1:CAS:528:DC%2BD2MXktFyru7s%3D (Pubitemid 40685604)
39. Marcha JA, Boulaiz H, Peran M, Prados JC, Campos J, Gonzalez FJ, Rodríguez-Serrano F, Melguizo C, Velez C, Carrillo E, Hita F, Ortiz R, Martinez-Amat A, Caba O, Ventura C, Aránega A (2009) Cancer stem cells and differentiation therapy. In: Macrcha JA et al. (ed) Therapeutic potential of differentiation in cancer and normal stem cells, 1st edn. Nova Science Publishers Inc, New York