Induction of fetal haemoglobin expression in erythroid cells - A model based on iron availability signalling

Medical Hypotheses

Volumn 65, Issue 5, 2005, Pages 932-936

  Delgado Canedo A ^a   Chies, J A B ^a   Nardi, N B ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ACLARUBICIN; CISPLATIN; CYTARABINE; DOXORUBICIN; HEMOGLOBIN F; HYDROXYUREA; IRON; ANTINEOPLASTIC ANTIBIOTIC; TUMOR PROTEIN;

ARTICLE; CELL ACTIVATION; CELL CYCLE; CELL DIFFERENTIATION; ERYTHROID CELL; GENE EXPRESSION; HEMOGLOBIN SYNTHESIS; HUMAN; HUMAN CELL; IRON TRANSPORT; LEUKEMIA CELL; METHODOLOGY; MODEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SICKLE CELL ANEMIA; SIGNAL TRANSDUCTION; THALASSEMIA; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL STRAIN K 562; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION REGULATION; METABOLISM;

ARA;

ACLARUBICIN; ANTIBIOTICS, ANTINEOPLASTIC; CELL DIFFERENTIATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; FETAL HEMOGLOBIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; K562 CELLS; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; SIGNAL TRANSDUCTION;

EID: 27244437936     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2005.02.046     Document Type: Article

References (28)

1. C.B. Lozzio, and B.B. Lozzio Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome Blood 45 3 1975 321 334
2. A.S. Tsiftsoglou, I.S. Pappas, and I.S. Vizirianakis Mechanisms involved in the induced differentiation of leukemia cells Pharmacol Ther 100 3 2003 257 290
3. F. Morceau, A. Aries, and R. Lahlil Evidence for distinct regulation processes in the aclacinomycin- and doxorubicin-mediated differentiation of human erythroleukemic cells Biochem Pharmacol 51 6 1996 839 845
4. R.B. Weiss The anthracyclines: will we ever find a better doxorubicin? Semin Oncol 19 6 1992 670 686
5. C. Mischiati, A. Sereni, and I. Lampronti Rapamycin-mediated induction of gamma-globin mRNA accumulation in human erythroid cells Br J Haematol 126 4 2004 612 621
6. C.M. Rodrigue, N. Arous, and D. Bachir Resveratrol, a natural dietary phytoalexin, possesses similar properties to hydroxyurea towards erythroid differentiation Br J Haematol 113 2 2001 500 507
7. I. Lampronti, N. Bianchi, M. Borgatti, E. Fibach, E. Prus, and R. Gambari Accumulation of gamma-globin mRNA in human erythroid cells treated with angelicin Eur J Haematol 71 3 2003 189 195
8. V.P. Cokic, R.D. Smith, and B.B. Beleslin-Cokic Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase J Clin Invest 111 2 2003 231 239
9. J. Haynes Jr., B.S. Baliga, B. Obiako, S. Ofori-Acquah, and B. Pace Zileuton induces hemoglobin F synthesis in erythroid progenitors: role of the l-arginine-nitric oxide signaling pathway Blood 103 10 2004 3945 3950
10. A. Inoue, Y. Kuroyanagi, K. Terui, P. Moi, and T. Ikuta Negative regulation of gamma-globin gene expression by cyclic AMP-dependent pathway in erythroid cells Exp Hematol 32 3 2004 244 253
11. N.T. Le, and D.R. Richardson The role of iron in cell cycle progression and the proliferation of neoplastic cells Biochim Biophys Acta 1603 1 2002 31 46 Review
12. M.E. Conrad, J.N. Umbreit, E.G. Moore, and D. Heiman Mobilferrin is an intermediate in iron transport between transferrin and hemoglobin in K562 cells J Clin Invest 98 6 1996 1449 1454
13. D.R. Richardson, and P. Ponka The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells Biochim Biophys Acta - Rev Biomembranes 1331 1 1997 1 40
14. M.W. Hentze, and L.C. Kuhn Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress Proc Natl Acad Sci USA 93 16 1996 8175 8182
15. K. Kokame, H. Kato, and T. Miyata Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes J Biol Chem 271 47 1996 29659 29665
16. 2+ compounds Cancer Res 58 10 1998 2182 2189
17. H. Park, M.A. Adams, P. Lachat, F. Bosman, S.C. Pang, and C.H. Graham Hypoxia induces the expression of a 43-kDa protein (PROXY-1) in normal and malignant cells Biochem Biophys Res Commun 276 1 2000 321 328
18. N.T. Le, and D.R. Richardson Iron chelators with high antiproliferative activity up-regulate the expression of a growth inhibitory and metastasis suppressor gene: a link between iron metabolism and proliferation Blood 104 9 2004 2967 2975
19. G. Minotti, P. Menna, E. Salvatorelli, G. Cairo, and L. Gianni Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity Pharmacol Rev 56 2 2004 185 229
20. C. Myers The role of iron in doxorubicin-induced cardiomyopathy Semin Oncol 25 4 Suppl. 10 1998 10 14
21. S. Kotamraju, C.R. Chitambar, S.V. Kalivendi, J. Joseph, and B. Kalyanaraman Transferrin receptor-dependent iron uptake is responsible for doxorubicin-mediated apoptosis in endothelial cells: role of oxidant-induced iron signaling in apoptosis J Biol Chem 277 19 2002 17179 17187
22. S. Nyholm, L. Thelander, and A. Graslund Reduction and loss of the iron center in the reaction of the small subunit of mouse ribonucleotide reductase with hydroxyurea Biochemistry 32 43 1993 11569 11574
23. A. Leardi, M. Caraglia, and C. Selleri Desferioxamine increases iron depletion and apoptosis induced by ara-C of human myeloid leukaemic cells Br J Haematol 102 3 1998 746 752
24. H. Zhuang, Y.S. Kim, R.C. Koehler, and S. Dore Potential mechanism by which resveratrol, a red wine constituent, protects neurons Ann N Y Acad Sci 993 2003 276 286
25. R. Mandal, R. Kalke, and X.F. Li Interaction of oxaliplatin, cisplatin, and carboplatin with hemoglobin and the resulting release of a heme group Chem Res Toxicol 17 10 2004 1391 1397
26. E. Leu, A. Krieger-Liszkay, C. Goussias, and E.M. Gross Polyphenolic allelochemicals from the aquatic angiosperm Myriophyllum spicatum inhibit photosystem II Plant Physiol 130 4 2002 2011 2018
27. P.R. Koduri Iron in sickle cell disease: a review why less is better Am J Hematol 73 1 2003 59 63
28. J.A. Chies, and N.B. Nardi Sickle cell disease: a chronic inflammatory condition Med Hypotheses 57 1 2001 46 50