메뉴 건너뛰기




Volumn 27, Issue 1, 2013, Pages 61-73

Granulocyte Colony-Stimulating Factor Receptor Signaling. Implications for G-CSF Responses and Leukemic Progression in Severe Congenital Neutropenia.

Author keywords

G CSF; G CSF receptor; Leukemia; Severe congenital neutropenia; Signal transduction

Indexed keywords

BORTEZOMIB; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; LEUKOCYTE ELASTASE; PROTEIN TYROSINE PHOSPHATASE 1B; REACTIVE OXYGEN METABOLITE; STAT5 PROTEIN;

EID: 84872715743     PISSN: 08898588     EISSN: 15581977     Source Type: Journal    
DOI: 10.1016/j.hoc.2012.10.002     Document Type: Review
Times cited : (22)

References (85)
  • 1
    • 0025885415 scopus 로고
    • Granulocyte colony-stimulating factor and its receptor
    • Demetri G.D., Griffin J.D. Granulocyte colony-stimulating factor and its receptor. Blood 1991, 78(11):2791-2808.
    • (1991) Blood , vol.78 , Issue.11 , pp. 2791-2808
    • Demetri, G.D.1    Griffin, J.D.2
  • 2
    • 0030640257 scopus 로고    scopus 로고
    • CSF-deficient mice-what have they taught us?
    • [discussion: 7]
    • Lieschke G.J. CSF-deficient mice-what have they taught us?. Ciba Found Symp 1997, 204:60-74. [discussion: 7].
    • (1997) Ciba Found Symp , vol.204 , pp. 60-74
    • Lieschke, G.J.1
  • 3
    • 0028000668 scopus 로고
    • Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization
    • Lieschke G.J., Grail D., Hodgson G., et al. Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization. Blood 1994, 84(6):1737-1746.
    • (1994) Blood , vol.84 , Issue.6 , pp. 1737-1746
    • Lieschke, G.J.1    Grail, D.2    Hodgson, G.3
  • 4
    • 0030292823 scopus 로고    scopus 로고
    • Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice
    • Liu F., Wu H.Y., Wesselschmidt R., et al. Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice. Immunity 1996, 5(5):491-501.
    • (1996) Immunity , vol.5 , Issue.5 , pp. 491-501
    • Liu, F.1    Wu, H.Y.2    Wesselschmidt, R.3
  • 5
    • 0025162844 scopus 로고
    • Structural design and molecular evolution of a cytokine receptor superfamily
    • Bazan J.F. Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci U S A 1990, 87(18):6934-6938.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , Issue.18 , pp. 6934-6938
    • Bazan, J.F.1
  • 6
    • 33744473092 scopus 로고    scopus 로고
    • The interaction of G-CSF with its receptor
    • Layton J.E., Hall N.E. The interaction of G-CSF with its receptor. Front Biosci 2006, 11:3181-3189.
    • (2006) Front Biosci , vol.11 , pp. 3181-3189
    • Layton, J.E.1    Hall, N.E.2
  • 7
    • 34249828162 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor and its receptor in normal myeloid cell development, leukemia and related blood cell disorders
    • Touw I.P., van de Geijn G.J. Granulocyte colony-stimulating factor and its receptor in normal myeloid cell development, leukemia and related blood cell disorders. Front Biosci 2007, 12:800-815.
    • (2007) Front Biosci , vol.12 , pp. 800-815
    • Touw, I.P.1    van de Geijn, G.J.2
  • 8
    • 33749510883 scopus 로고    scopus 로고
    • LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
    • Skokowa J., Cario G., Uenalan M., et al. LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia. Nat Med 2006, 12(10):1191-1197.
    • (2006) Nat Med , vol.12 , Issue.10 , pp. 1191-1197
    • Skokowa, J.1    Cario, G.2    Uenalan, M.3
  • 9
    • 59649125761 scopus 로고    scopus 로고
    • NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway
    • Skokowa J., Lan D., Thakur B.K., et al. NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway. Nat Med 2009, 15(2):151-158.
    • (2009) Nat Med , vol.15 , Issue.2 , pp. 151-158
    • Skokowa, J.1    Lan, D.2    Thakur, B.K.3
  • 10
    • 0033557171 scopus 로고    scopus 로고
    • Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene
    • Hermans M.H., Antonissen C., Ward A.C., et al. Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene. J Exp Med 1999, 189(4):683-692.
    • (1999) J Exp Med , vol.189 , Issue.4 , pp. 683-692
    • Hermans, M.H.1    Antonissen, C.2    Ward, A.C.3
  • 11
    • 0036338213 scopus 로고    scopus 로고
    • STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation
    • Lee C.K., Raz R., Gimeno R., et al. STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation. Immunity 2002, 17(1):63-72.
    • (2002) Immunity , vol.17 , Issue.1 , pp. 63-72
    • Lee, C.K.1    Raz, R.2    Gimeno, R.3
  • 12
    • 0033591347 scopus 로고    scopus 로고
    • Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells
    • Ward A.C., Smith L., de Koning J.P., et al. Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells. J Biol Chem 1999, 274(21):14956-14962.
    • (1999) J Biol Chem , vol.274 , Issue.21 , pp. 14956-14962
    • Ward, A.C.1    Smith, L.2    de Koning, J.P.3
  • 13
    • 0038784346 scopus 로고    scopus 로고
    • Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells
    • Hermans M.H., van de Geijn G.J., Antonissen C., et al. Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells. Blood 2003, 101(7):2584-2590.
    • (2003) Blood , vol.101 , Issue.7 , pp. 2584-2590
    • Hermans, M.H.1    van de Geijn, G.J.2    Antonissen, C.3
  • 14
    • 0036681955 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction
    • Hortner M., Nielsch U., Mayr L.M., et al. Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction. J Immunol 2002, 169(3):1219-1227.
    • (2002) J Immunol , vol.169 , Issue.3 , pp. 1219-1227
    • Hortner, M.1    Nielsch, U.2    Mayr, L.M.3
  • 15
    • 0030068525 scopus 로고    scopus 로고
    • Specific involvement of tyrosine 764 of human granulocyte colony-stimulating factor receptor in signal transduction mediated by p145/Shc/GRB2 or p90/GRB2 complexes
    • de Koning J.P., Schelen A.M., Dong F., et al. Specific involvement of tyrosine 764 of human granulocyte colony-stimulating factor receptor in signal transduction mediated by p145/Shc/GRB2 or p90/GRB2 complexes. Blood 1996, 87(1):132-140.
    • (1996) Blood , vol.87 , Issue.1 , pp. 132-140
    • de Koning, J.P.1    Schelen, A.M.2    Dong, F.3
  • 16
    • 0032521221 scopus 로고    scopus 로고
    • Proliferation signaling and activation of Shc, p21Ras, and Myc via tyrosine 764 of human granulocyte colony-stimulating factor receptor
    • de Koning J.P., Soede-Bobok A.A., Schelen A.M., et al. Proliferation signaling and activation of Shc, p21Ras, and Myc via tyrosine 764 of human granulocyte colony-stimulating factor receptor. Blood 1998, 91(6):1924-1933.
    • (1998) Blood , vol.91 , Issue.6 , pp. 1924-1933
    • de Koning, J.P.1    Soede-Bobok, A.A.2    Schelen, A.M.3
  • 17
    • 33846921639 scopus 로고    scopus 로고
    • The role of the granulocyte colony-stimulating factor receptor (G-CSF-R) in disease
    • Ward A.C. The role of the granulocyte colony-stimulating factor receptor (G-CSF-R) in disease. Front Biosci 2007, 12:608-618.
    • (2007) Front Biosci , vol.12 , pp. 608-618
    • Ward, A.C.1
  • 18
    • 84856830351 scopus 로고    scopus 로고
    • IFNgamma induces monopoiesis and inhibits neutrophil development during inflammation
    • de Bruin A.M., Libregts S.F., Valkhof M., et al. IFNgamma induces monopoiesis and inhibits neutrophil development during inflammation. Blood 2012, 119(6):1543-1554.
    • (2012) Blood , vol.119 , Issue.6 , pp. 1543-1554
    • de Bruin, A.M.1    Libregts, S.F.2    Valkhof, M.3
  • 19
    • 58249084744 scopus 로고    scopus 로고
    • The many causes of severe congenital neutropenia
    • Dale D.C., Link D.C. The many causes of severe congenital neutropenia. N Engl J Med 2009, 360(1):3-5.
    • (2009) N Engl J Med , vol.360 , Issue.1 , pp. 3-5
    • Dale, D.C.1    Link, D.C.2
  • 21
    • 33847395071 scopus 로고    scopus 로고
    • Neutrophil elastase in cyclic and severe congenital neutropenia
    • Horwitz M.S., Duan Z., Korkmaz B., et al. Neutrophil elastase in cyclic and severe congenital neutropenia. Blood 2007, 109(5):1817-1824.
    • (2007) Blood , vol.109 , Issue.5 , pp. 1817-1824
    • Horwitz, M.S.1    Duan, Z.2    Korkmaz, B.3
  • 22
    • 33845904894 scopus 로고    scopus 로고
    • HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease)
    • Klein C., Grudzien M., Appaswamy G., et al. HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease). Nat Genet 2007, 39(1):86-92.
    • (2007) Nat Genet , vol.39 , Issue.1 , pp. 86-92
    • Klein, C.1    Grudzien, M.2    Appaswamy, G.3
  • 23
    • 0036221569 scopus 로고    scopus 로고
    • Risk of myelodysplastic syndrome and acute myeloid leukemia in congenital neutropenias
    • Freedman M.H., Alter B.P. Risk of myelodysplastic syndrome and acute myeloid leukemia in congenital neutropenias. Semin Hematol 2002, 39(2):128-133.
    • (2002) Semin Hematol , vol.39 , Issue.2 , pp. 128-133
    • Freedman, M.H.1    Alter, B.P.2
  • 24
    • 0011982978 scopus 로고    scopus 로고
    • Myelodysplasia syndrome and acute myeloid leukemia in patients with congenital neutropenia receiving G-CSF therapy
    • Freedman M.H., Bonilla M.A., Fier C., et al. Myelodysplasia syndrome and acute myeloid leukemia in patients with congenital neutropenia receiving G-CSF therapy. Blood 2000, 96(2):429-436.
    • (2000) Blood , vol.96 , Issue.2 , pp. 429-436
    • Freedman, M.H.1    Bonilla, M.A.2    Fier, C.3
  • 25
    • 0027269718 scopus 로고
    • A randomized controlled phase III trial of recombinant human granulocyte colony-stimulating factor (filgrastim) for treatment of severe chronic neutropenia
    • Dale D.C., Bonilla M.A., Davis M.W., et al. A randomized controlled phase III trial of recombinant human granulocyte colony-stimulating factor (filgrastim) for treatment of severe chronic neutropenia. Blood 1993, 81(10):2496-2502.
    • (1993) Blood , vol.81 , Issue.10 , pp. 2496-2502
    • Dale, D.C.1    Bonilla, M.A.2    Davis, M.W.3
  • 26
    • 12244255076 scopus 로고    scopus 로고
    • Severe chronic neutropenia: treatment and follow-up of patients in the Severe Chronic Neutropenia International Registry
    • Dale D.C., Cottle T.E., Fier C.J., et al. Severe chronic neutropenia: treatment and follow-up of patients in the Severe Chronic Neutropenia International Registry. Am J Hematol 2003, 72(2):82-93.
    • (2003) Am J Hematol , vol.72 , Issue.2 , pp. 82-93
    • Dale, D.C.1    Cottle, T.E.2    Fier, C.J.3
  • 27
    • 33745096897 scopus 로고    scopus 로고
    • The incidence of leukemia and mortality from sepsis in patients with severe congenital neutropenia receiving long-term G-CSF therapy
    • Rosenberg P.S., Alter B.P., Bolyard A.A., et al. The incidence of leukemia and mortality from sepsis in patients with severe congenital neutropenia receiving long-term G-CSF therapy. Blood 2006, 107(12):4628-4635.
    • (2006) Blood , vol.107 , Issue.12 , pp. 4628-4635
    • Rosenberg, P.S.1    Alter, B.P.2    Bolyard, A.A.3
  • 28
    • 58549087140 scopus 로고    scopus 로고
    • Clinical implications of ELA2-, HAX1-, and G-CSF-receptor (CSF3R) mutations in severe congenital neutropenia
    • Zeidler C., Germeshausen M., Klein C., et al. Clinical implications of ELA2-, HAX1-, and G-CSF-receptor (CSF3R) mutations in severe congenital neutropenia. Br J Haematol 2009, 144(4):459-467.
    • (2009) Br J Haematol , vol.144 , Issue.4 , pp. 459-467
    • Zeidler, C.1    Germeshausen, M.2    Klein, C.3
  • 29
    • 0029129034 scopus 로고
    • Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia
    • Dong F., Brynes R.K., Tidow N., et al. Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia. N Engl J Med 1995, 333(8):487-493.
    • (1995) N Engl J Med , vol.333 , Issue.8 , pp. 487-493
    • Dong, F.1    Brynes, R.K.2    Tidow, N.3
  • 30
    • 0028328265 scopus 로고
    • Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia
    • Dong F., Hoefsloot L.H., Schelen A.M., et al. Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia. Proc Natl Acad Sci U S A 1994, 91(10):4480-4484.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , Issue.10 , pp. 4480-4484
    • Dong, F.1    Hoefsloot, L.H.2    Schelen, A.M.3
  • 31
    • 16944361974 scopus 로고    scopus 로고
    • Mutations in the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia
    • Dong F., Dale D.C., Bonilla M.A., et al. Mutations in the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia. Leukemia 1997, 11(1):120-125.
    • (1997) Leukemia , vol.11 , Issue.1 , pp. 120-125
    • Dong, F.1    Dale, D.C.2    Bonilla, M.A.3
  • 32
    • 0030945921 scopus 로고    scopus 로고
    • Clinical relevance of point mutations in the cytoplasmic domain of the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia
    • Tidow N., Pilz C., Teichmann B., et al. Clinical relevance of point mutations in the cytoplasmic domain of the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia. Blood 1997, 89(7):2369-2375.
    • (1997) Blood , vol.89 , Issue.7 , pp. 2369-2375
    • Tidow, N.1    Pilz, C.2    Teichmann, B.3
  • 33
    • 0027488081 scopus 로고
    • Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation
    • Dong F., van Buitenen C., Pouwels K., et al. Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation. Mol Cell Biol 1993, 13(12):7774-7781.
    • (1993) Mol Cell Biol , vol.13 , Issue.12 , pp. 7774-7781
    • Dong, F.1    van Buitenen, C.2    Pouwels, K.3
  • 34
    • 0027433327 scopus 로고
    • Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor
    • Fukunaga R., Ishizaka-Ikeda E., Nagata S. Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor. Cell 1993, 74(6):1079-1087.
    • (1993) Cell , vol.74 , Issue.6 , pp. 1079-1087
    • Fukunaga, R.1    Ishizaka-Ikeda, E.2    Nagata, S.3
  • 35
    • 0032126619 scopus 로고    scopus 로고
    • Perturbed granulopoiesis in mice with a targeted mutation in the granulocyte colony-stimulating factor receptor gene associated with severe chronic neutropenia
    • Hermans M.H., Ward A.C., Antonissen C., et al. Perturbed granulopoiesis in mice with a targeted mutation in the granulocyte colony-stimulating factor receptor gene associated with severe chronic neutropenia. Blood 1998, 92(1):32-39.
    • (1998) Blood , vol.92 , Issue.1 , pp. 32-39
    • Hermans, M.H.1    Ward, A.C.2    Antonissen, C.3
  • 36
    • 0032146530 scopus 로고    scopus 로고
    • Increased granulocyte colony-stimulating factor responsiveness but normal resting granulopoiesis in mice carrying a targeted granulocyte colony-stimulating factor receptor mutation derived from a patient with severe congenital neutropenia
    • McLemore M.L., Poursine-Laurent J., Link D.C. Increased granulocyte colony-stimulating factor responsiveness but normal resting granulopoiesis in mice carrying a targeted granulocyte colony-stimulating factor receptor mutation derived from a patient with severe congenital neutropenia. J Clin Invest 1998, 102(3):483-492.
    • (1998) J Clin Invest , vol.102 , Issue.3 , pp. 483-492
    • McLemore, M.L.1    Poursine-Laurent, J.2    Link, D.C.3
  • 37
    • 33344461473 scopus 로고    scopus 로고
    • G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth
    • Zhu Q.S., Xia L., Mills G.B., et al. G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth. Blood 2006, 107(5):1847-1856.
    • (2006) Blood , vol.107 , Issue.5 , pp. 1847-1856
    • Zhu, Q.S.1    Xia, L.2    Mills, G.B.3
  • 38
    • 40549121259 scopus 로고    scopus 로고
    • Csf3r mutations in mice confer a strong clonal HSC advantage via activation of Stat5
    • Liu F., Kunter G., Krem M.M., et al. Csf3r mutations in mice confer a strong clonal HSC advantage via activation of Stat5. J Clin Invest 2008, 118(3):946-955.
    • (2008) J Clin Invest , vol.118 , Issue.3 , pp. 946-955
    • Liu, F.1    Kunter, G.2    Krem, M.M.3
  • 39
    • 0942287735 scopus 로고    scopus 로고
    • Receptor activation and 2 distinct COOH-terminal motifs control G-CSF receptor distribution and internalization kinetics
    • Aarts L.H., Roovers O., Ward A.C., et al. Receptor activation and 2 distinct COOH-terminal motifs control G-CSF receptor distribution and internalization kinetics. Blood 2004, 103(2):571-579.
    • (2004) Blood , vol.103 , Issue.2 , pp. 571-579
    • Aarts, L.H.1    Roovers, O.2    Ward, A.C.3
  • 40
    • 0033555439 scopus 로고    scopus 로고
    • Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia
    • Ward A.C., van Aesch Y.M., Schelen A.M., et al. Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia. Blood 1999, 93(2):447-458.
    • (1999) Blood , vol.93 , Issue.2 , pp. 447-458
    • Ward, A.C.1    van Aesch, Y.M.2    Schelen, A.M.3
  • 41
    • 69249137477 scopus 로고    scopus 로고
    • Endocytosis and signalling: intertwining molecular networks
    • Sorkin A., von Zastrow M. Endocytosis and signalling: intertwining molecular networks. Nat Rev Mol Cell Biol 2009, 10(9):609-622.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , Issue.9 , pp. 609-622
    • Sorkin, A.1    von Zastrow, M.2
  • 42
    • 33644769212 scopus 로고    scopus 로고
    • Endocytosis conducts the cell signaling orchestra
    • Polo S., Di Fiore P.P. Endocytosis conducts the cell signaling orchestra. Cell 2006, 124(5):897-900.
    • (2006) Cell , vol.124 , Issue.5 , pp. 897-900
    • Polo, S.1    Di Fiore, P.P.2
  • 43
    • 75749096347 scopus 로고    scopus 로고
    • The endocytic matrix
    • Scita G., Di Fiore P.P. The endocytic matrix. Nature 2010, 463(7280):464-473.
    • (2010) Nature , vol.463 , Issue.7280 , pp. 464-473
    • Scita, G.1    Di Fiore, P.P.2
  • 44
    • 63049107267 scopus 로고    scopus 로고
    • Systems biology of growth factor-induced receptor endocytosis
    • Zwang Y., Yarden Y. Systems biology of growth factor-induced receptor endocytosis. Traffic 2009, 10(4):349-363.
    • (2009) Traffic , vol.10 , Issue.4 , pp. 349-363
    • Zwang, Y.1    Yarden, Y.2
  • 45
    • 34247242299 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 3 controls lysosomal routing of G-CSF receptor
    • Irandoust M.I., Aarts L.H., Roovers O., et al. Suppressor of cytokine signaling 3 controls lysosomal routing of G-CSF receptor. EMBO J 2007, 26(7):1782-1793.
    • (2007) EMBO J , vol.26 , Issue.7 , pp. 1782-1793
    • Irandoust, M.I.1    Aarts, L.H.2    Roovers, O.3
  • 46
    • 67649888820 scopus 로고    scopus 로고
    • Site-specific ubiquitination determines lysosomal sorting and signal attenuation of the granulocyte colony-stimulating factor receptor
    • Wolfler A., Irandoust M., Meenhuis A., et al. Site-specific ubiquitination determines lysosomal sorting and signal attenuation of the granulocyte colony-stimulating factor receptor. Traffic 2009, 10(8):1168-1179.
    • (2009) Traffic , vol.10 , Issue.8 , pp. 1168-1179
    • Wolfler, A.1    Irandoust, M.2    Meenhuis, A.3
  • 47
    • 0032217156 scopus 로고    scopus 로고
    • C-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor
    • Levkowitz G., Waterman H., Zamir E., et al. c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor. Genes Dev 1998, 12(23):3663-3674.
    • (1998) Genes Dev , vol.12 , Issue.23 , pp. 3663-3674
    • Levkowitz, G.1    Waterman, H.2    Zamir, E.3
  • 48
    • 54249151578 scopus 로고    scopus 로고
    • Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
    • Umebayashi K., Stenmark H., Yoshimori T. Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation. Mol Biol Cell 2008, 19(8):3454-3462.
    • (2008) Mol Biol Cell , vol.19 , Issue.8 , pp. 3454-3462
    • Umebayashi, K.1    Stenmark, H.2    Yoshimori, T.3
  • 49
    • 22144453890 scopus 로고    scopus 로고
    • Ubiquitination of the common cytokine receptor gammac and regulation of expression by an ubiquitination/deubiquitination machinery
    • Gesbert F., Malarde V., Dautry-Varsat A. Ubiquitination of the common cytokine receptor gammac and regulation of expression by an ubiquitination/deubiquitination machinery. Biochem Biophys Res Commun 2005, 334(2):474-480.
    • (2005) Biochem Biophys Res Commun , vol.334 , Issue.2 , pp. 474-480
    • Gesbert, F.1    Malarde, V.2    Dautry-Varsat, A.3
  • 50
    • 77949525475 scopus 로고    scopus 로고
    • Ubiquitination and degradation of the thrombopoietin receptor c-Mpl
    • Saur S.J., Sangkhae V., Geddis A.E., et al. Ubiquitination and degradation of the thrombopoietin receptor c-Mpl. Blood 2010, 115(6):1254-1263.
    • (2010) Blood , vol.115 , Issue.6 , pp. 1254-1263
    • Saur, S.J.1    Sangkhae, V.2    Geddis, A.E.3
  • 51
    • 47949124200 scopus 로고    scopus 로고
    • C-Cbl-dependent monoubiquitination and lysosomal degradation of gp130
    • Tanaka Y., Tanaka N., Saeki Y., et al. c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130. Mol Cell Biol 2008, 28(15):4805-4818.
    • (2008) Mol Cell Biol , vol.28 , Issue.15 , pp. 4805-4818
    • Tanaka, Y.1    Tanaka, N.2    Saeki, Y.3
  • 52
    • 34250027624 scopus 로고    scopus 로고
    • Beta-Trcp mediates ubiquitination and degradation of the erythropoietin receptor and controls cell proliferation
    • Meyer L., Deau B., Forejtnikova H., et al. beta-Trcp mediates ubiquitination and degradation of the erythropoietin receptor and controls cell proliferation. Blood 2007, 109(12):5215-5222.
    • (2007) Blood , vol.109 , Issue.12 , pp. 5215-5222
    • Meyer, L.1    Deau, B.2    Forejtnikova, H.3
  • 53
    • 0038711771 scopus 로고    scopus 로고
    • Erythropoietin receptors associate with a ubiquitin ligase, p33RUL, and require its activity for erythropoietin-induced proliferation
    • Friedman A.D., Nimbalkar D., Quelle F.W. Erythropoietin receptors associate with a ubiquitin ligase, p33RUL, and require its activity for erythropoietin-induced proliferation. J Biol Chem 2003, 278(29):26851-26861.
    • (2003) J Biol Chem , vol.278 , Issue.29 , pp. 26851-26861
    • Friedman, A.D.1    Nimbalkar, D.2    Quelle, F.W.3
  • 54
    • 0344440953 scopus 로고    scopus 로고
    • Regulation of cytokine signaling by SOCS family molecules
    • Fujimoto M., Naka T. Regulation of cytokine signaling by SOCS family molecules. Trends Immunol 2003, 24(12):659-666.
    • (2003) Trends Immunol , vol.24 , Issue.12 , pp. 659-666
    • Fujimoto, M.1    Naka, T.2
  • 55
    • 0036558025 scopus 로고    scopus 로고
    • The SOCS box: a tale of destruction and degradation
    • Kile B.T., Schulman B.A., Alexander W.S., et al. The SOCS box: a tale of destruction and degradation. Trends Biochem Sci 2002, 27(5):235-241.
    • (2002) Trends Biochem Sci , vol.27 , Issue.5 , pp. 235-241
    • Kile, B.T.1    Schulman, B.A.2    Alexander, W.S.3
  • 56
    • 0032803530 scopus 로고    scopus 로고
    • Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain
    • Sasaki A., Yasukawa H., Suzuki A., et al. Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain. Genes Cells 1999, 4(6):339-351.
    • (1999) Genes Cells , vol.4 , Issue.6 , pp. 339-351
    • Sasaki, A.1    Yasukawa, H.2    Suzuki, A.3
  • 57
    • 34249660614 scopus 로고    scopus 로고
    • SOCS proteins, cytokine signalling and immune regulation
    • Yoshimura A., Naka T., Kubo M. SOCS proteins, cytokine signalling and immune regulation. Nat Rev Immunol 2007, 7(6):454-465.
    • (2007) Nat Rev Immunol , vol.7 , Issue.6 , pp. 454-465
    • Yoshimura, A.1    Naka, T.2    Kubo, M.3
  • 58
    • 10644276385 scopus 로고    scopus 로고
    • VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases
    • Kamura T., Maenaka K., Kotoshiba S., et al. VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases. Genes Dev 2004, 18(24):3055-3065.
    • (2004) Genes Dev , vol.18 , Issue.24 , pp. 3055-3065
    • Kamura, T.1    Maenaka, K.2    Kotoshiba, S.3
  • 59
    • 34548834429 scopus 로고    scopus 로고
    • The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo
    • Boyle K., Egan P., Rakar S., et al. The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo. Blood 2007, 110(5):1466-1474.
    • (2007) Blood , vol.110 , Issue.5 , pp. 1466-1474
    • Boyle, K.1    Egan, P.2    Rakar, S.3
  • 60
    • 3042696495 scopus 로고    scopus 로고
    • Distinct activities of suppressor of cytokine signaling (SOCS) proteins and involvement of the SOCS box in controlling G-CSF signaling
    • van de Geijn G.J., Gits J., Touw I.P. Distinct activities of suppressor of cytokine signaling (SOCS) proteins and involvement of the SOCS box in controlling G-CSF signaling. J Leukoc Biol 2004, 76(1):237-244.
    • (2004) J Leukoc Biol , vol.76 , Issue.1 , pp. 237-244
    • van de Geijn, G.J.1    Gits, J.2    Touw, I.P.3
  • 61
    • 1642576123 scopus 로고    scopus 로고
    • DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes
    • Baek K.H., Kim M.S., Kim Y.S., et al. DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes. J Biol Chem 2004, 279(4):2368-2376.
    • (2004) J Biol Chem , vol.279 , Issue.4 , pp. 2368-2376
    • Baek, K.H.1    Kim, M.S.2    Kim, Y.S.3
  • 62
    • 0035437161 scopus 로고    scopus 로고
    • DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes
    • Baek K.H., Mondoux M.A., Jaster R., et al. DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes. Blood 2001, 98(3):636-642.
    • (2001) Blood , vol.98 , Issue.3 , pp. 636-642
    • Baek, K.H.1    Mondoux, M.A.2    Jaster, R.3
  • 63
    • 0031032943 scopus 로고    scopus 로고
    • DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes
    • Zhu Y., Lambert K., Corless C., et al. DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes. J Biol Chem 1997, 272(1):51-57.
    • (1997) J Biol Chem , vol.272 , Issue.1 , pp. 51-57
    • Zhu, Y.1    Lambert, K.2    Corless, C.3
  • 64
    • 0029783927 scopus 로고    scopus 로고
    • The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor
    • Zhu Y., Pless M., Inhorn R., et al. The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor. Mol Cell Biol 1996, 16(9):4808-4817.
    • (1996) Mol Cell Biol , vol.16 , Issue.9 , pp. 4808-4817
    • Zhu, Y.1    Pless, M.2    Inhorn, R.3
  • 65
    • 79951537425 scopus 로고    scopus 로고
    • The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor
    • Meenhuis A., Verwijmeren C., Roovers O., et al. The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor. Biochem J 2011, 434(2):343-351.
    • (2011) Biochem J , vol.434 , Issue.2 , pp. 343-351
    • Meenhuis, A.1    Verwijmeren, C.2    Roovers, O.3
  • 66
    • 59849094269 scopus 로고    scopus 로고
    • Janus kinases promote cell-surface expression and provoke autonomous signalling from routing-defective G-CSF receptors
    • Meenhuis A., Irandoust M., Wolfler A., et al. Janus kinases promote cell-surface expression and provoke autonomous signalling from routing-defective G-CSF receptors. Biochem J 2009, 417(3):737-746.
    • (2009) Biochem J , vol.417 , Issue.3 , pp. 737-746
    • Meenhuis, A.1    Irandoust, M.2    Wolfler, A.3
  • 67
    • 70349645650 scopus 로고    scopus 로고
    • G-CSF receptor (CSF3R) mutations in X-linked neutropenia evolving to acute myeloid leukemia or myelodysplasia
    • Beel K., Vandenberghe P. G-CSF receptor (CSF3R) mutations in X-linked neutropenia evolving to acute myeloid leukemia or myelodysplasia. Haematologica 2009, 94(10):1449-1452.
    • (2009) Haematologica , vol.94 , Issue.10 , pp. 1449-1452
    • Beel, K.1    Vandenberghe, P.2
  • 68
    • 0038752667 scopus 로고    scopus 로고
    • Haematopoietic lineage cell-specific protein 1 (HS1) promotes actin-related protein (Arp) 2/3 complex-mediated actin polymerization
    • Uruno T., Zhang P., Liu J., et al. Haematopoietic lineage cell-specific protein 1 (HS1) promotes actin-related protein (Arp) 2/3 complex-mediated actin polymerization. Biochem J 2003, 371(Pt 2):485-493.
    • (2003) Biochem J , vol.371 , Issue.PART 2 , pp. 485-493
    • Uruno, T.1    Zhang, P.2    Liu, J.3
  • 69
    • 0031047432 scopus 로고    scopus 로고
    • Increased G-CSF responsiveness of bone marrow cells from hematopoietic cell phosphatase deficient viable motheaten mice
    • Tapley P., Shevde N.K., Schweitzer P.A., et al. Increased G-CSF responsiveness of bone marrow cells from hematopoietic cell phosphatase deficient viable motheaten mice. Exp Hematol 1997, 25(2):122-131.
    • (1997) Exp Hematol , vol.25 , Issue.2 , pp. 122-131
    • Tapley, P.1    Shevde, N.K.2    Schweitzer, P.A.3
  • 70
    • 38349004658 scopus 로고    scopus 로고
    • The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway
    • Dance M., Montagner A., Salles J.P., et al. The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway. Cell Signal 2008, 20(3):453-459.
    • (2008) Cell Signal , vol.20 , Issue.3 , pp. 453-459
    • Dance, M.1    Montagner, A.2    Salles, J.P.3
  • 71
    • 0038771965 scopus 로고    scopus 로고
    • The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
    • Neel B.G., Gu H., Pao L. The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem Sci 2003, 28(6):284-293.
    • (2003) Trends Biochem Sci , vol.28 , Issue.6 , pp. 284-293
    • Neel, B.G.1    Gu, H.2    Pao, L.3
  • 72
    • 81355138441 scopus 로고    scopus 로고
    • Peroxiredoxin-controlled G-CSF signalling at the endoplasmic reticulum-early endosome interface
    • Palande K., Roovers O., Gits J., et al. Peroxiredoxin-controlled G-CSF signalling at the endoplasmic reticulum-early endosome interface. J Cell Sci 2011, 124(Pt 21):3695-3705.
    • (2011) J Cell Sci , vol.124 , Issue.PART 21 , pp. 3695-3705
    • Palande, K.1    Roovers, O.2    Gits, J.3
  • 73
    • 78049253878 scopus 로고    scopus 로고
    • In control at the ER: PTP1B and the down-regulation of RTKs by dephosphorylation and endocytosis
    • Stuible M., Tremblay M.L. In control at the ER: PTP1B and the down-regulation of RTKs by dephosphorylation and endocytosis. Trends Cell Biol 2010, 20:672-679.
    • (2010) Trends Cell Biol , vol.20 , pp. 672-679
    • Stuible, M.1    Tremblay, M.L.2
  • 74
    • 0026584285 scopus 로고
    • The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence
    • Frangioni J.V., Beahm P.H., Shifrin V., et al. The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence. Cell 1992, 68(3):545-560.
    • (1992) Cell , vol.68 , Issue.3 , pp. 545-560
    • Frangioni, J.V.1    Beahm, P.H.2    Shifrin, V.3
  • 75
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
    • Bedard K., Krause K.H. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 2007, 87(1):245-313.
    • (2007) Physiol Rev , vol.87 , Issue.1 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 76
    • 46249108461 scopus 로고    scopus 로고
    • Regulation of ROS signal transduction by NADPH oxidase 4 localization
    • Chen K., Kirber M.T., Xiao H., et al. Regulation of ROS signal transduction by NADPH oxidase 4 localization. J Cell Biol 2008, 181(7):1129-1139.
    • (2008) J Cell Biol , vol.181 , Issue.7 , pp. 1129-1139
    • Chen, K.1    Kirber, M.T.2    Xiao, H.3
  • 77
    • 0035877633 scopus 로고    scopus 로고
    • Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade
    • Mahadev K., Zilbering A., Zhu L., et al. Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade. J Biol Chem 2001, 276(4):21938-21942.
    • (2001) J Biol Chem , vol.276 , Issue.4 , pp. 21938-21942
    • Mahadev, K.1    Zilbering, A.2    Zhu, L.3
  • 78
    • 4444233558 scopus 로고    scopus 로고
    • Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B
    • Meng T.C., Buckley D.A., Galic S., et al. Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. J Biol Chem 2004, 279(36):37716-37725.
    • (2004) J Biol Chem , vol.279 , Issue.36 , pp. 37716-37725
    • Meng, T.C.1    Buckley, D.A.2    Galic, S.3
  • 79
    • 84856940017 scopus 로고    scopus 로고
    • Peroxiredoxin functions as a peroxidase and a regulator and sensor of local peroxides
    • Rhee S.G., Woo H.A., Kil I.S., et al. Peroxiredoxin functions as a peroxidase and a regulator and sensor of local peroxides. J Biol Chem 2012, 287(7):4403-4410.
    • (2012) J Biol Chem , vol.287 , Issue.7 , pp. 4403-4410
    • Rhee, S.G.1    Woo, H.A.2    Kil, I.S.3
  • 80
    • 19644394554 scopus 로고    scopus 로고
    • Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II
    • Choi M.H., Lee I.K., Kim G.W., et al. Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II. Nature 2005, 435(7040):347-353.
    • (2005) Nature , vol.435 , Issue.7040 , pp. 347-353
    • Choi, M.H.1    Lee, I.K.2    Kim, G.W.3
  • 81
    • 76749102420 scopus 로고    scopus 로고
    • Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling
    • Woo H.A., Yim S.H., Shin D.H., et al. Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling. Cell 2010, 140(4):517-528.
    • (2010) Cell , vol.140 , Issue.4 , pp. 517-528
    • Woo, H.A.1    Yim, S.H.2    Shin, D.H.3
  • 82
    • 41649110016 scopus 로고    scopus 로고
    • Peroxiredoxin IV is an endoplasmic reticulum-localized enzyme forming oligomeric complexes in human cells
    • Tavender T.J., Sheppard A.M., Bulleid N.J. Peroxiredoxin IV is an endoplasmic reticulum-localized enzyme forming oligomeric complexes in human cells. Biochem J 2008, 411(1):191-199.
    • (2008) Biochem J , vol.411 , Issue.1 , pp. 191-199
    • Tavender, T.J.1    Sheppard, A.M.2    Bulleid, N.J.3
  • 83
    • 79251629982 scopus 로고    scopus 로고
    • The antioxidant protein peroxiredoxin 4 is epigenetically down regulated in acute promyelocytic leukemia
    • Palande K.K., Beekman R., van der Meeren L.E., et al. The antioxidant protein peroxiredoxin 4 is epigenetically down regulated in acute promyelocytic leukemia. PLoS One 2011, 6(1):e16340.
    • (2011) PLoS One , vol.6 , Issue.1
    • Palande, K.K.1    Beekman, R.2    van der Meeren, L.E.3
  • 84
    • 33845972945 scopus 로고    scopus 로고
    • Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: results of a long-term survey
    • Germeshausen M., Ballmaier M., Welte K. Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: results of a long-term survey. Blood 2007, 109(1):93-99.
    • (2007) Blood , vol.109 , Issue.1 , pp. 93-99
    • Germeshausen, M.1    Ballmaier, M.2    Welte, K.3
  • 85
    • 84861813715 scopus 로고    scopus 로고
    • Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia
    • Beekman R., Valkhof M.G., Sanders M.A., et al. Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia. Blood 2012, 119(22):5071-5077.
    • (2012) Blood , vol.119 , Issue.22 , pp. 5071-5077
    • Beekman, R.1    Valkhof, M.G.2    Sanders, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.