The Antioxidant Protein Peroxiredoxin 4 Is Epigenetically Down Regulated in Acute Promyelocytic Leukemia

PLoS ONE

Volumn 6, Issue 1, 2011, Pages

  Palande, Karishma K ^a   Beekman, Renee ^a   van der Meeren, Lotte E ^a   Berna Beverloo, H ^a   Valk, Peter J M ^a   Touw, Ivo P ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; HISTONE H3; METHYLATED HISTONE H3 LYSINE 24; METHYLATED HISTONE H3 LYSINE 27; PEROXIREDOXIN 4; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; ANTIOXIDANT; GRANULOCYTE COLONY STIMULATING FACTOR; HISTONE; LYSINE; PEROXIREDOXIN; PRDX4 PROTEIN, HUMAN;

ALLELE; ARTICLE; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE LOCUS; GENE MUTATION; GENE SILENCING; HISTONE CODE; HISTONE METHYLATION; HUMAN; HUMAN CELL; KARYOTYPING; MALE; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROMYELOCYTE; PROMYELOCYTIC LEUKEMIA; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; GENETIC EPIGENESIS; GENETICS; METABOLISM; METHYLATION;

ANTIOXIDANTS; DOWN-REGULATION; EPIGENESIS, GENETIC; GRANULOCYTE COLONY-STIMULATING FACTOR; HISTONES; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; LYSINE; METHYLATION; PEROXIREDOXINS; TRANSCRIPTION INITIATION SITE;

EID: 79251629982     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016340     Document Type: Article

References (26)

1. Touw IP, van de Geijn GJ (2007) Granulocyte colony-stimulating factor and its receptor in normal myeloid cell development, leukemia and related blood cell disorders. Front Biosci 12: 800-815.
2. Irandoust MI, Aarts LH, Roovers O, Gits J, Erkeland SJ, et al. (2007) Suppressor of cytokine signaling 3 controls lysosomal routing of G-CSF receptor. Embo J 26: 1782-1793.
3. Wölfler A, Irandoust M, Meenhuis A, Gits J, Roovers O, et al. (2009) Sitespecific ubiquitination determines lysosomal sorting and signal attenuation of the granulocyte colony-stimulating factor receptor. Traffic 10: 1168-1179.
4. Dong F, Brynes RK, Tidow N, Welte K, Löwenberg B, et al. (1995) Mutations in the Gene for the Granulocyte Colony-Stimulating-Factor Receptor in Patients with Acute Myeloid Leukemia Preceded by Severe Congenital Neutropenia. The New England Journal of Medicine 333: 487-493.
5. Freedman MH, Alter BP (2002) Risk of myelodysplastic syndrome and acute myeloid leukemia in congenital neutropenias. Semin Hematol 39: 128-133.
6. Germeshausen M, Ballmaier M, Welte K (2007) Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: Results of a long-term survey. Blood 109: 93-99.
7. Zhu QS, Xia L, Mills GB, Lowell CA, Touw IP, et al. (2006) G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth. Blood 107: 1847-1856.
8. Tonks NK (2006) Protein tyrosine phosphatases: from genes, to function, to disease. Nat Rev Mol Cell Biol 7: 833-846.
9. Tonks NK (2005) Redox redux: revisiting PTPs and the control of cell signaling. Cell Jun 3 121: 667-670.
10. Rhee SG, Chae HZ, Kim K (2005) Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. Free Radic Biol Med 38: 1543-1552.
11. Rhee SG, Kang SW, Jeong W, Chang TS, Yang KS, et al. (2005) Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins. Curr Opin Cell Biol 17: 183-189.
12. Zhang Y, Emmanuel N, Kamboj G, Chen J, Shurafa M, et al. (2004) PRDX4, a member of the peroxiredoxin family, is fused to AML1 (RUNX1) in an acute myeloid leukemia patient with a t(X;21)(p22;q22). Genes Chromosomes Cancer 40: 365-370.
13. Pébusque MJ, Lafage M, Lopez M, Mannoni P (1988) Preferential response of acute myeloid leukemias with translocation involving chromosome 17 to human recombinant granulocyte colony-stimulating factor. Blood 72: 257-265.
14. Verhaak RG, Valk PJ (2009) Genes predictive of outcome and novel molecular classification schemes in adult acute myeloid leukemia. Cancer Treat Res 145: 67-83.
15. Wang HQ, Du ZX, Liu BQ, Gao YY, Meng X, et al. (2009) TNF-related apoptosis-inducing ligand suppresses PRDX4 expression. FEBS Lett 583: 1511-1515.
16. Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M, et al. (2002) Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 295: 1079-1082.
17. Villa R, Pasini D, Gutierrez A, Morey L, Occhionorelli M, et al. (2007) Role of the polycomb repressive complex 2 in acute promyelocytic leukemia. Cancer Cell 11: 513-525.
18. Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, et al. (2002) Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298: 1039-1043.
19. Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, et al. (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125: 315-326.
20. Minucci S, Maccarana M, Cioce M, De Luca P, Gelmetti V, et al. (2000) Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation. Mol Cell 5: 811-820.
21. van Wageningen S, Breems-de Ridder MC, Nigten J, Nikoloski G, Erpelinck-Verschueren CAJ, et al. (2008) Gene transactivation without direct DNA binding defines a novel gain-of-function for PML-RAR. Blood 111: 1634-1643.
22. Jiang X, Tan J, Li J, Kivimäe S, Yang X, et al. (2008) DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. Cancer Cell 13: 529-541.
23. Tavender TJ, Sheppard AM, Bulleid NJ (2008) Peroxiredoxin IV is an endoplasmic reticulum-localized enzyme forming oligomeric complexes in human cells. Biochem J 411: 191-199.
24. Valk PJ, Verhaak RG, Beijen MA, Erpelinck CA, Barjesteh van Waalwijk van Doorn-Khosrovani S, et al. (2004) Prognostically useful gene-expression profiles in acute myeloid leukemia. N Engl J Med 350: 1617-1628.
25. von Bergh AR, van Drunen E, van Wering ER, van Zutven LJ, Hainmann I, et al. (2006) High incidence of t(7;12)(q36;p13) in infant AML but not in infant ALL, with a dismal outcome and ectopic expression of HLXB9. Genes Chromosomes Cancer 45: 731-739.
26. Vakoc CR, Sachdeva MM, Wang H, Blobel GA (2006) Profile of histone lysine methylation across transcribed mammalian chromatin. Mol Cell Biol 26: 9185-9195.