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Volumn 5, Issue 3, 2013, Pages 1005-1009

Embelin-induced MCF-7 breast cancer cell apoptosis and blockade of MCF-7 cells in the G2/M phase via the mitochondrial pathway

Author keywords

Apoptosis; Breast cancer MCF 7 cell; Embelin; Mitochondria; XIAP

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; EMBELIN; PROTEIN BAX; PROTEIN BCL 2;

EID: 84872705918     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2012.1084     Document Type: Article
Times cited : (28)

References (25)
  • 1
    • 85007758538 scopus 로고    scopus 로고
    • ABC of breast diseases. Breast cancer-epidemiology, risk factors, and genetics
    • McPherson K, Steel CM and Dixon JM: ABC of breast diseases. Breast cancer-epidemiology, risk factors, and genetics. BMJ 321: 624-628, 2000.
    • (2000) BMJ , vol.321 , pp. 624-628
    • McPherson, K.1    Steel, C.M.2    Dixon, J.M.3
  • 2
    • 84863688143 scopus 로고    scopus 로고
    • The global breast cancer burden
    • Benson JR and Jatoi I: The global breast cancer burden. Future Oncol 8: 697-702, 2012.
    • (2012) Future Oncol , vol.8 , pp. 697-702
    • Benson, J.R.1    Jatoi, I.2
  • 3
    • 80053279974 scopus 로고    scopus 로고
    • Incidence of breast cancer in the United States: Current and future trends
    • Anderson WF, Katki HA and Rosenberg PS: Incidence of breast cancer in the United States: current and future trends. J Natl Cancer Inst 103: 1397-1402, 2011.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 1397-1402
    • Anderson, W.F.1    Katki, H.A.2    Rosenberg, P.S.3
  • 4
    • 78649673612 scopus 로고    scopus 로고
    • Embelin suppresses osteoclastogenesis induced by receptor activator of NF-κB ligand and tumor cells invitro through inhibition of the NF-κB cell signaling pathway
    • Reuter S, Prasad S, Phromnoi K, Kannappan R, Yadav VR and AggarwalBB: Embelin suppresses osteoclastogenesis induced by receptor activator of NF-κB ligand and tumor cells invitro through inhibition of the NF-κB cell signaling pathway. Mol Cancer Res 8: 1425-1436, 2010.
    • (2010) Mol Cancer Res , vol.8 , pp. 1425-1436
    • Reuter, S.1    Prasad, S.2    Phromnoi, K.3    Kannappan, R.4    Yadav, V.R.5    Aggarwal, B.B.6
  • 5
    • 84655175089 scopus 로고    scopus 로고
    • Embelin induces apoptosis through down-regulation of XIAP in human leukemia cells
    • Hu R, Zhu K, Li Y, Yao K, Zhang R, Wang H, Yang W and Liu Z: Embelin induces apoptosis through down-regulation of XIAP in human leukemia cells. Med Oncol 28: 1584-1588, 2011.
    • (2011) Med Oncol , vol.28 , pp. 1584-1588
    • Hu, R.1    Zhu, K.2    Li, Y.3    Yao, K.4    Zhang, R.5    Wang, H.6    Yang, W.7    Liu, Z.8
  • 6
    • 2342448582 scopus 로고    scopus 로고
    • Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database
    • Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, RollerPP, Wang R, Fang X, Guo R, Zhang M, Lippman ME, Yang D and Wang S: Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database. J Med Chem 47: 2430-2440, 2004.
    • (2004) J Med Chem , vol.47 , pp. 2430-2440
    • Nikolovska-Coleska, Z.1    Xu, L.2    Hu, Z.3    Tomita, Y.4    Li, P.5    Roller, P.P.6    Wang, R.7    Fang, X.8    Guo, R.9    Zhang, M.10    Lippman, M.E.11    Yang, D.12    Wang, S.13
  • 7
    • 33947651075 scopus 로고    scopus 로고
    • Free radical scavenging reactions and antioxidant activity of embelin: Biochemical and pulse radiolytic studies
    • Joshi R, Kamat JP and Mukherjee T: Free radical scavenging reactions and antioxidant activity of embelin: biochemical and pulse radiolytic studies. Chem Biol Interact 167: 125-134, 2007.
    • (2007) Chem Biol Interact , vol.167 , pp. 125-134
    • Joshi, R.1    Kamat, J.P.2    Mukherjee, T.3
  • 8
    • 33745907263 scopus 로고    scopus 로고
    • Effects of administration of Embelin and Curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during N-nitrosodiethylamine/Phenobarbital-induced hepatocarcinogenesis in Wistar rats
    • Sreepriya M and Bali G: Effects of administration of Embelin and Curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during N-nitrosodiethylamine/Phenobarbital-induced hepatocarcinogenesis in Wistar rats. Mol Cell Biochem 284: 49-55, 2006.
    • (2006) Mol Cell Biochem , vol.284 , pp. 49-55
    • Sreepriya, M.1    Bali, G.2
  • 9
    • 79961108124 scopus 로고    scopus 로고
    • Synthesis and evaluation of analgesic and anti-inflammatory activities of most active free radical scavenging derivatives of embelin-A structure-activity relationship
    • Mahendran S, Badami S, Ravi S, Thippeswamy BS and VeerapurVP: Synthesis and evaluation of analgesic and anti-inflammatory activities of most active free radical scavenging derivatives of embelin-A structure-activity relationship. Chem Pharm Bull 59: 913-919, 2011.
    • (2011) Chem Pharm Bull , vol.59 , pp. 913-919
    • Mahendran, S.1    Badami, S.2    Ravi, S.3    Thippeswamy, B.S.4    Veerapur, V.P.5
  • 11
    • 68149132860 scopus 로고    scopus 로고
    • Micellar delivery of bicalutamide and embelin for treating prostate cancer
    • Danquah M, Li F, Duke CB III, Miller DD and MahatoRI: Micellar delivery of bicalutamide and embelin for treating prostate cancer. Pharm Res 26: 2081-2092, 2009.
    • (2009) Pharm Res , vol.26 , pp. 2081-2092
    • Danquah, M.1    Li, F.2    Duke III, C.B.3    Miller, D.D.4    Mahato, R.I.5
  • 12
    • 66349089835 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis
    • Dai Y, Qiao L, Chan KW, Yang M, Ye J, Ma J, Zou B, Gu Q, Wang J, Pang R, Lan HY and Wong BC: Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis. Cancer Res 69: 4776-4783, 2009.
    • (2009) Cancer Res , vol.69 , pp. 4776-4783
    • Dai, Y.1    Qiao, L.2    Chan, K.W.3    Yang, M.4    Ye, J.5    Ma, J.6    Zou, B.7    Gu, Q.8    Wang, J.9    Pang, R.10    Lan, H.Y.11    Wong, B.C.12
  • 13
    • 38349155799 scopus 로고    scopus 로고
    • Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression
    • Aird KM, Ding X, Baras A, Wei J, Morse MA, Clay T, LyerlyHK and Devi GR: Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression. Mol Cancer Ther 7: 38-47, 2008.
    • (2008) Mol Cancer Ther , vol.7 , pp. 38-47
    • Aird, K.M.1    Ding, X.2    Baras, A.3    Wei, J.4    Morse, M.A.5    Clay, T.6    Lyerly, H.K.7    Devi, G.R.8
  • 15
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH and Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26: 239-257, 1972.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 16
    • 55949128465 scopus 로고    scopus 로고
    • Anoikis: A necessary death program for anchorage-dependent cells
    • Chiarugi P and Giannoni E: Anoikis: a necessary death program for anchorage-dependent cells. Biochem Pharmacol 76: 1352-1364, 2008.
    • (2008) Biochem Pharmacol , vol.76 , pp. 1352-1364
    • Chiarugi, P.1    Giannoni, E.2
  • 17
    • 84863790379 scopus 로고    scopus 로고
    • XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells
    • Allensworth JL, Aird KM, Aldrich AJ, Batinic-Haberle I and DeviGR: XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells. Mol Cancer Ther 11: 1518-1527, 2012.
    • (2012) Mol Cancer Ther , vol.11 , pp. 1518-1527
    • Allensworth, J.L.1    Aird, K.M.2    Aldrich, A.J.3    Batinic-Haberle, I.4    Devi, G.R.5
  • 18
    • 80053481523 scopus 로고    scopus 로고
    • Activation of the δ-opioid receptor inhibits serum deprivation-induced apoptosis of human liver cells via the activation of PKC and the mitochondrial pathway
    • Tang B, Zhang Y, Liang R, Yuan P, Du J, Wang H and Wang L: Activation of the δ-opioid receptor inhibits serum deprivation-induced apoptosis of human liver cells via the activation of PKC and the mitochondrial pathway. Int J Mol Med 28: 1077-1085, 2011.
    • (2011) Int J Mol Med , vol.28 , pp. 1077-1085
    • Tang, B.1    Zhang, Y.2    Liang, R.3    Yuan, P.4    Du, J.5    Wang, H.6    Wang, L.7
  • 19
    • 0013198976 scopus 로고    scopus 로고
    • Mitochondria in cell death: Novel targets for neuroprotection and cardioprotection
    • Mattson MP and Kroemer G: Mitochondria in cell death: novel targets for neuroprotection and cardioprotection. Trends Mol Med 9: 196-205, 2003.
    • (2003) Trends Mol Med , vol.9 , pp. 196-205
    • Mattson, M.P.1    Kroemer, G.2
  • 20
    • 0242522206 scopus 로고    scopus 로고
    • Regulation of apoptosis by Bcl-2 family proteins
    • Burlacu A: Regulation of apoptosis by Bcl-2 family proteins. JCell Mol Med 7: 249-257, 2003.
    • (2003) JCell Mol Med , vol.7 , pp. 249-257
    • Burlacu, A.1
  • 21
    • 0034253592 scopus 로고    scopus 로고
    • BAX-dependent transport of cytochrome c reconstituted in pure liposomes
    • Saito M, Korsmeyer SJ and Schlesinger PH: BAX-dependent transport of cytochrome c reconstituted in pure liposomes. Nat Cell Biol 2: 553-555, 2000.
    • (2000) Nat Cell Biol , vol.2 , pp. 553-555
    • Saito, M.1    Korsmeyer, S.J.2    Schlesinger, P.H.3
  • 23
    • 84862113237 scopus 로고    scopus 로고
    • Apoptotic and non-apoptotic roles of caspases in neuronal physiology and pathophysiology
    • Hyman BT and Yuan J: Apoptotic and non-apoptotic roles of caspases in neuronal physiology and pathophysiology. Nat Rev Neurosci 13: 395-406, 2012.
    • (2012) Nat Rev Neurosci , vol.13 , pp. 395-406
    • Hyman, B.T.1    Yuan, J.2
  • 24
    • 8444220527 scopus 로고    scopus 로고
    • Molecular mechanisms of caspase regulation during apoptosis
    • Riedl SJ and Shi Y: Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 5: 897-907, 2004.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 897-907
    • Riedl, S.J.1    Shi, Y.2
  • 25
    • 33744484725 scopus 로고    scopus 로고
    • Inhibition of microvascular endothelial cell apoptosis by angiopoietin-1 and the involvement of cytochrome C
    • Shi LG, Zhang GP and Jin HM: Inhibition of microvascular endothelial cell apoptosis by angiopoietin-1 and the involvement of cytochrome C. Chin Med J (Engl) 119: 725-730, 2006.
    • (2006) Chin Med J (Engl) , vol.119 , pp. 725-730
    • Shi, L.G.1    Zhang, G.P.2    Jin, H.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.