Diammonium Glycyrrhizinate Attenuates Aβ1-42-Induced Neuroinflammation and Regulates MAPK and NF-κB Pathways In Vitro and In Vivo

CNS Neuroscience and Therapeutics

Volumn 19, Issue 2, 2013, Pages 117-124

  Zhao, Hui ^a,b   Wang, Su Lei ^a   Qian, Lai ^b   Jin, Jia Li ^b   Li, Hui ^a   Xu, Yun ^a,b,c   Zhu, Xiao Lei ^a,b,c  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^c NANJING UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Beta amyloid; Diammonium glycyrrhizinate; Inflammation; MAPK; NF B pathway

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; CYTOKINE; DIAMMONIUM GLYCYRRHIZINATE; GLYCYRRHIZIC ACID DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATTENUATION; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFICACY; DRUG INHIBITION; ENZYME ACTIVATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MEMORY DISORDER; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AMYLOID BETA-PEPTIDES; ANIMALS; CELL LINE, TUMOR; GLYCYRRHIZIC ACID; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED ICR; NF-KAPPA B; PEPTIDE FRAGMENTS;

EID: 84872684830     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12043     Document Type: Article

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