메뉴 건너뛰기




Volumn 5, Issue 1, 2011, Pages 51-52

Will o' the wisp: CCN4 as a novel molecular target in osteoarthritis

Author keywords

Cartilage; CCN4; Osteoarthritis; WISP 1; Wnt

Indexed keywords

CCN PROTEIN; CCN4 PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 79953029383     PISSN: 18739601     EISSN: 1873961X     Source Type: Journal    
DOI: 10.1007/s12079-010-0110-2     Document Type: Conference Paper
Times cited : (7)

References (21)
  • 1
    • 64849101721 scopus 로고    scopus 로고
    • Topical therapy for osteoarthritis: Clinical and pharmacologic perspectives
    • 10.3810/pgm.2009.03.1986 19332972
    • R Altman RL Barkin 2009 Topical therapy for osteoarthritis: clinical and pharmacologic perspectives Postgrad Med 121 139 147 10.3810/pgm.2009.03.1986 19332972
    • (2009) Postgrad Med , vol.121 , pp. 139-147
    • Altman, R.1    Barkin, R.L.2
  • 3
    • 77951073232 scopus 로고    scopus 로고
    • To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy
    • 10.2174/138945010791011901 1:CAS:528:DC%2BC3cXmtFegsLg%3D 20199388
    • AB Blom PL van Lent PM van der Kraan WB van den Berg 2010 To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy Curr Drug Targets 11 620 629 10.2174/138945010791011901 1:CAS:528:DC%2BC3cXmtFegsLg%3D 20199388
    • (2010) Curr Drug Targets , vol.11 , pp. 620-629
    • Blom, A.B.1    Van Lent, P.L.2    Van Der Kraan, P.M.3    Van Den Berg, W.B.4
  • 4
    • 33847183465 scopus 로고    scopus 로고
    • Molecular targets in osteoarthritis: Metalloproteinases and their inhibitors
    • 10.2174/138945007779940098 1:CAS:528:DC%2BD2sXhs1ygsrw%3D 17305507
    • PS Burrage CE Brinckerhoff 2007 Molecular targets in osteoarthritis: metalloproteinases and their inhibitors Curr Drug Targets 8 293 303 10.2174/138945007779940098 1:CAS:528:DC%2BD2sXhs1ygsrw%3D 17305507
    • (2007) Curr Drug Targets , vol.8 , pp. 293-303
    • Burrage, P.S.1    Brinckerhoff, C.E.2
  • 5
    • 67349118137 scopus 로고    scopus 로고
    • Wnt 10b activates the CCN2 promoter in NIH 3T3 fibroblasts through the Smad response element
    • 10.1007/s12079-009-0049-3 19353303
    • S Chen A Leask 2009 Wnt 10b activates the CCN2 promoter in NIH 3T3 fibroblasts through the Smad response element J Cell Commun Signal 3 57 59 10.1007/s12079-009-0049-3 19353303
    • (2009) J Cell Commun Signal , vol.3 , pp. 57-59
    • Chen, S.1    Leask, A.2
  • 6
    • 9444299108 scopus 로고    scopus 로고
    • CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin
    • DOI 10.1091/mbc.E04-06-0490
    • Y Chen DJ Abraham X Shi-Wen JD Pearson CM Black KM Lyons A Leask 2004 CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin Mol Biol Cell 15 5635 5646 10.1091/mbc.E04-06-0490 1:CAS:528:DC%2BD2cXhtVGlsLbI 15371538 (Pubitemid 39564754)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.12 , pp. 5635-5646
    • Chen, Y.1    Abraham, D.J.2    Shi-Wen, X.3    Pearson, J.D.4    Black, C.M.5    Lyons, K.M.6    Leask, A.7
  • 7
    • 55849119491 scopus 로고    scopus 로고
    • The gene expression profile induced by Wnt 3a in NIH 3 T3 fibroblasts
    • 10.1007/s12079-007-0015-x 18600477
    • S Chen S McLean DE Carter A Leask 2007 The gene expression profile induced by Wnt 3a in NIH 3 T3 fibroblasts J Cell Commun Signal 1 175 183 10.1007/s12079-007-0015-x 18600477
    • (2007) J Cell Commun Signal , vol.1 , pp. 175-183
    • Chen, S.1    McLean, S.2    Carter, D.E.3    Leask, A.4
  • 8
    • 0034304209 scopus 로고    scopus 로고
    • The increasing impact of arthritis on Public Health
    • MJ Elders 2000 The increasing impact of arthritis on Public Health J Rheumatol 27 6 8
    • (2000) J Rheumatol , vol.27 , pp. 6-8
    • Elders, M.J.1
  • 10
    • 33646821004 scopus 로고    scopus 로고
    • 1 binding domain in module 4 of connective tissue growth factor (CCN2/CTGF) promotes adhesion and migration of activated pancreatic stellate cells
    • DOI 10.1136/gut.2005.079178
    • R Gao DR Brigstock 2006 A novel integrin alpha5beta1 binding domain in module 4 of connective tissue growth factor (CCN2/CTGF) promotes adhesion and migration of activated pancreatic stellate cells Gut 55 856 862 10.1136/gut.2005.079178 1:CAS:528:DC%2BD28XlvVOhtL4%3D 16361307 (Pubitemid 43764558)
    • (2006) Gut , vol.55 , Issue.6 , pp. 856-862
    • Gao, R.1    Brigstock, D.R.2
  • 11
    • 32344444422 scopus 로고    scopus 로고
    • CT domain of CCN2/CTGF directly interacts with fibronectin and enhances cell adhesion of chondrocytes through integrin α5β1
    • DOI 10.1016/j.febslet.2006.01.061, PII S0014579306001141
    • M Hoshijima T Hattori M Inoue D Araki H Hanagata A Miyauchi M Takigawa 2006 CT domain of CCN2/CTGF directly interacts with fibronectin and enhances cell adhesion of chondrocytes through integrin alpha5beta1 FEBS Lett 580 1376 1382 10.1016/j.febslet.2006.01.061 1:CAS:528:DC%2BD28Xhs1Snt78%3D 16457822 (Pubitemid 43222004)
    • (2006) FEBS Letters , vol.580 , Issue.5 , pp. 1376-1382
    • Hoshijima, M.1    Hattori, T.2    Inoue, M.3    Araki, D.4    Hanagata, H.5    Miyauchi, A.6    Takigawa, M.7
  • 13
    • 38149052992 scopus 로고    scopus 로고
    • Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II
    • 10.1002/art.23176 18163497
    • RC Lawrence DT Felson CG Helmick LM Arnold H Choi RA Deyo, et al. 2008 Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II Arthritis Rheum 58 26 35 10.1002/art.23176 18163497
    • (2008) Arthritis Rheum , vol.58 , pp. 26-35
    • Lawrence, R.C.1    Felson, D.T.2    Helmick, C.G.3    Arnold, L.M.4    Choi, H.5    Deyo, R.A.6
  • 14
    • 77952429470 scopus 로고    scopus 로고
    • Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome
    • 10.1038/jid.2010.15 1:CAS:528:DC%2BC3cXlvFOjur0%3D 20182440
    • R Lemaire G Farina J Bayle M Dimarzio SA Pendergrass A Milano B Perbal ML Whitfield R Lafyatis 2010 Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome J Invest Dermatol 130 1514 1523 10.1038/jid.2010.15 1:CAS:528:DC%2BC3cXlvFOjur0%3D 20182440
    • (2010) J Invest Dermatol , vol.130 , pp. 1514-1523
    • Lemaire, R.1    Farina, G.2    Bayle, J.3    Dimarzio, M.4    Pendergrass, S.A.5    Milano, A.6    Perbal, B.7    Whitfield, M.L.8    Lafyatis, R.9
  • 16
    • 68849094898 scopus 로고    scopus 로고
    • Surgical options for patients with osteoarthritis of the knee
    • 10.1038/nrrheum.2009.88 19491912
    • J Lützner P Kasten KP Günther S Kirschner 2009 Surgical options for patients with osteoarthritis of the knee Nat Rev Rheumatol 5 309 316 10.1038/nrrheum.2009.88 19491912
    • (2009) Nat Rev Rheumatol , vol.5 , pp. 309-316
    • Lützner, J.1    Kasten, P.2    Günther, K.P.3    Kirschner, S.4
  • 17
    • 21244440341 scopus 로고    scopus 로고
    • Expression profiles and functional analyses of Wnt-related genes in human joint disorders
    • Y Nakamura M Nawata S Wakitani 2005 Expression profiles and functional analyses of Wnt-related genes in human joint disorders Am J Pathol 167 97 105 10.1016/S0002-9440(10)62957-4 1:CAS:528:DC%2BD2MXms1eitr4%3D 15972956 (Pubitemid 40884774)
    • (2005) American Journal of Pathology , vol.167 , Issue.1 , pp. 97-105
    • Nakamura, Y.1    Nawata, M.2    Wakitani, S.3
  • 18
    • 84856017089 scopus 로고    scopus 로고
    • New horizons in osteoarthritis
    • 10.4414/smw.2010.13098 1:STN:280:DC%2BC3cfltlygtw%3D%3D 20458653
    • F Oliviero R Ramonda L Punzi 2010 New horizons in osteoarthritis Swiss Med Wkly 140 w13098 10.4414/smw.2010.13098 1:STN:280:DC%2BC3cfltlygtw%3D%3D 20458653
    • (2010) Swiss Med Wkly , vol.140 , pp. 13098
    • Oliviero, F.1    Ramonda, R.2    Punzi, L.3
  • 19
    • 79953026603 scopus 로고    scopus 로고
    • WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity
    • Aug 3. [Epub ahead of print] 2010
    • Ono M, Inkson CA, Kilts TM, Young MF (2010) WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity. J Bone Miner Res. 2010 Aug 3. [Epub ahead of print]
    • (2010) J Bone Miner Res.
    • Ono, M.1    Inkson, C.A.2    Kilts, T.M.3    Young, M.F.4
  • 21
    • 33645816535 scopus 로고    scopus 로고
    • CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells
    • 10.1128/MCB.26.8.2955-2964.2006 1:CAS:528:DC%2BD28Xjs1SlsbY%3D 16581771
    • W Si Q Kang HH Luu JK Park Q Luo WX Song W Jiang X Luo X Li H Yin AG Montag RC Haydon TC He 2006 CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells Mol Cell Biol 26 2955 2964 10.1128/MCB.26.8.2955-2964. 2006 1:CAS:528:DC%2BD28Xjs1SlsbY%3D 16581771
    • (2006) Mol Cell Biol , vol.26 , pp. 2955-2964
    • Si, W.1    Kang, Q.2    Luu, H.H.3    Park, J.K.4    Luo, Q.5    Song, W.X.6    Jiang, W.7    Luo, X.8    Li, X.9    Yin, H.10    Montag, A.G.11    Haydon, R.C.12    He, T.C.13


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.