Inhibition of WTA synthesis blocks the cooperative action of pbps and sensitizes MRSA to β-lactams

ACS Chemical Biology

Volumn 8, Issue 1, 2013, Pages 226-233

  Farha, Maya A ^a   Leung, Alexander ^a   Sewell, Edward W ^a   D'Elia, Michael A ^a   Allison, Sarah E ^a   Ejim, Linda ^a   Pereira, Pedro M ^b   Pinho, Mariana G ^b   Wright, Gerard D ^a   Brown, Eric D ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; BACTERIAL PROTEIN; BETA LACTAM ANTIBIOTIC; CEFACLOR; CEFADROXIL; CEFUROXIME; CHLORAMPHENICOL; CLARITHROMYCIN; CYCLOSERINE; DAPTOMYCIN; ERYTHROMYCIN; FOSFOMYCIN; KANAMYCIN; LEVOFLOXACIN; MINOCYCLINE; N ACETYLGLUCOSAMINE 1 PHOSPHATE TRANSFERASE; NEOMYCIN; NORFLOXACIN; NOVOBIOCIN; PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 2; PENICILLIN BINDING PROTEIN 4; PEPTIDOGLYCAN; STREPTOMYCIN; TEICHOIC ACID; TETRACYCLINE; TICLOPIDINE; TRIMETHOPRIM; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL MEMBRANE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; DRUG SCREENING; DRUG SENSITIZATION; DRUG TARGETING; EXPERIMENTAL MODEL; GALLERIA MELLONELLA; GENE DELETION; IN VITRO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN FUNCTION; PROTEIN STABILITY; TARO GENE;

BETA-LACTAMS; CELL WALL; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; PENICILLIN-BINDING PROTEINS; TEICHOIC ACIDS;

COLOCASIA ESCULENTA; GALLERIA MELLONELLA; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 84872572985     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb300413m     Document Type: Article

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